Crohn's disease associated with gastric cancer.

abstract：:A case of heterotopic gastric mucosa in the fundus of the gallbladder is reported. A 23-year-old man, who had been healthy and asymptomatic, visited our hospital because of abnormal findings in a liver enzyme test given during a routine health screening. Ultrasonography demonstrated a highly echogenic polypoid mass in...

journal_title：Journal of gastroenterology

authors： Uchiyama S,Imai S,Suzuki T,Arita A,Takeda K,Sujino H,Kameda H

更新日期：1995-08-01 00:00:00

abstract：:We report a 13-year-old girl who presented with hepatic failure and hemolytic anemia. Laboratory findings showed a normal serum copper level (104 microg/dl), high urinary copper level (2370 microg/dl), and low serum ceruloplasmin level (14.3 microg/dl). Slit-lamp examination revealed Kayser-Fleischer rings on her corn...

journal_title：Journal of gastroenterology

authors： Sakaida I,Kawaguchi K,Kimura T,Tamura F,Okita K

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:The p53 tumor suppressor protein plays a fundamental role in maintaining genomic integrity through its ability to arrest the cell cycle in G1 and induce apoptosis. The proapoptotic activity of p53 seems to be strictly related to proline-rich regions, homologous to the SH3 binding domain. In the literature, r...

journal_title：Journal of gastroenterology

authors： Vietri MT,Riegler G,Ursillo A,Caserta L,Cioffi M,Molinari AM

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:Oropharyngeal dysphagia (OD) is a major gastrointestinal motility disorder that causes severe nutritional and respiratory complications in elderly and neurological patients. In an earlier study, we found that stimulation of pharyngeal sensory neurons by capsaicinoids acting on transient receptor potential va...

journal_title：Journal of gastroenterology

authors： Rofes L,Arreola V,Martin A,Clavé P

更新日期：2014-12-01 00:00:00

abstract：:Gastric mucosal lesions are an important complication in endotoxemia. In order to define the role played by the vagus nerve and endothelial-derived relaxing factor (EDRF) in gastric mucosal blood flow, an investigation was carried out on four groups of rats: a control group; a group given lipopolysaccharide (LPS, 5 mg...

journal_title：Journal of gastroenterology

authors： Sakano T,Itoh K,Tanaka M,Arakawa Y,Matsuo Y

更新日期：1995-02-01 00:00:00

abstract：BACKGROUND:Endotoxin modulates esophageal motor function by increasing nitric oxide (NO) production. The aims of this study were to examine inducible nitric oxide synthase (iNOS) induction in the lower esophageal sphincter (LES) of endotoxemic opossums and to investigate the effects of aminoguanidine (AG), a selective ...

journal_title：Journal of gastroenterology

authors： Park H,Clark E,Cullen JJ,Koland JG,Kim MS,Conklin JL

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Polymorphisms in the gene for interleukin 1beta (IL-1B) have been found to increase the risks of gastric cancer and its precursors in response to Helicobacter pylori infection in white populations. however, there has been no independent confirmation of the role of IL-1B markers in gastric cancer patients fro...

journal_title：Journal of gastroenterology

authors： Lee KA,Ki CS,Kim HJ,Sohn KM,Kim JW,Kang WK,Rhee JC,Song SY,Sohn TS

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Circular RNAs (circRNAs) act as vital regulators of gene expression in a variety of cancers. However, the role of circRNAs in gastric cancer (GC) remains largely unexplored. Herein, we identified that circTMEM87A sponges miR-142-5p to promote GC progression through up-regulating ULK1 expression. METHODS:The...

journal_title：Journal of gastroenterology

authors： Wang H,Sun G,Xu P,Lv J,Zhang X,Zhang L,Wang S,Cao J,Xia Y,Xuan Z,Li B,Huang X,Jiang T,Fang L,Xu Z

更新日期：2020-11-06 00:00:00

abstract：:A 27-year-old woman with a 9-year history of ulcerative colitis involving the entire colon was admitted to our hospital in August 1992 because of bloody stools and left lower abdominal pain. She had been treated with sulfasalazine since 1983 and the colitis had been clinically quiescent or mild for 7 years. She had al...

journal_title：Journal of gastroenterology

authors： Seo M,Okada M,Osamura S,Hara S,Umeno T,Maeshiro K,Yamada Y,Yuh K

更新日期：1997-02-01 00:00:00

abstract：:We report a case of living-related partial liver transplantation for decompensated hepatitis B without reactivation of hepatitis B in the following 30 months, and we analyze the factors that indicate a favorable prognosis for transplantation. The 42-year-old female patient received continuously administered lamivudine...

journal_title：Journal of gastroenterology

authors： Hasegawa K,Hashimoto E,Kanai N,Ogawa M,Naritomi T,Taniai M,Takasaki K,Hayashi N

更新日期：2001-09-01 00:00:00

abstract：:Perianal fistulae are frequently seen complications in Crohn's disease. Although surgical procedures such as Seton's method have been devised, many patients still suffer from fistulae that are resistant to conventional therapy. We administered oral adsorbent to a patient with disease Crohn's who had a complicated peri...

journal_title：Journal of gastroenterology

authors： Tsujikawa T,Araki Y,Makino J,Uda K,Ihara T,Sasaki M,Fujiyama Y,Bamba T

更新日期：2000-01-01 00:00:00

abstract：:A rare case of simple ulcer of the colon in a 7-year-old girl is reported. Simple ulcer is clinically and pathologically recognized as a serious disease linked to intestinal Behcet's disease. Recently, some immunomodulators, such as thalidomide and antitumor necrosis factor monoclonal antibody, have been used to treat...

journal_title：Journal of gastroenterology

authors： Kasahara E,Yamagishi N,Tanaka M,Yashiro K

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Most studies evaluating visceral sensation measure visceromotor response (VMR) to colorectal distention (CRD). However, CRD itself induces visceral sensitization, and little is known about the detailed characteristics of this response. The present study tried to clarify this question. METHODS:VMR was determ...

journal_title：Journal of gastroenterology

authors： Nozu T,Kumei S,Miyagishi S,Takakusaki K,Okumura T

更新日期：2015-12-01 00:00:00

abstract：:Cytosolic phospholipase A2 (PLase A2) is activated by low Ca2+ concentrations and translocates from the cytosol to the cell membrane, releasing arachidonic acid; the arachidonic acid cascade then leads to the production of many inflammatory mediators. The aim of this study, accordingly, was to investigate the role of ...

journal_title：Journal of gastroenterology

authors： Morita H,Nakanishi K,Dohi T,Yasugi E,Oshima M

更新日期：1999-02-01 00:00:00

abstract：:A patient with hepatitis C virus (HCV)-related liver cirrhosis and hepatocellular carcinoma (HCC) was treated successfully with an orthotopic liver transplantation (OLT) followed by interferon therapy. The 36-year-old Japanese man was diagnosed as having liver cirrhosis in 1983. HCC was detected in 1991, and by 1994, ...

journal_title：Journal of gastroenterology

authors： Shibata M,Yanaga K,Morizane T,Yanagawa T,Hirakawa M,Ueno Y,Esquivel CO,Mitamura K

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Aberrant methylation of some cancer-related genes has been reported to correlate with sensitivity to chemotherapeutic agents. The present study was designed to determine whether DNA methylation in six cancer-related genes affects recurrence of gastric cancer in patients who received 5-fluorouracil-based adju...

journal_title：Journal of gastroenterology

authors： Mitsuno M,Kitajima Y,Ide T,Ohtaka K,Tanaka M,Satoh S,Miyazaki K

更新日期：2007-11-01 00:00:00

abstract：:We investigated the adverse effects of sulfasalazine in the treatment of inflammatory bowel disease in Japan. In our first survey, adverse effects were observed in 52 out of 751 patients with ulcerative colitis (6.9%) and in 8 out of 221 patients with Crohn's disease (3.6%); i.e., such effects were observed in 60 out ...

journal_title：Journal of gastroenterology

authors： Nakajima H,Munakata A,Yoshida Y

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:Linked color imaging (LCI) increases the visibility of early gastric cancers, which may be associated with characteristic findings including background purple mucosae. These lesions are found in areas of chronic gastritis and surrounding mucosa. The aim of this study is to objectively characterize these lesi...

journal_title：Journal of gastroenterology

authors： Fukuda H,Miura Y,Osawa H,Takezawa T,Ino Y,Okada M,Khurelbaatar T,Lefor AK,Yamamoto H

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:To further clarify the clinico-epidemiological features of autoimmune pancreatitis (AIP) in Japan, we conducted the fourth nationwide epidemiological survey. METHODS:This study consisted of two stage surveys; the number of AIP patients was estimated by the first survey and their clinical features were asses...

journal_title：Journal of gastroenterology

authors： Masamune A,Kikuta K,Hamada S,Tsuji I,Takeyama Y,Shimosegawa T,Okazaki K,Collaborators.

更新日期：2020-04-01 00:00:00

abstract：:Our objective was to determine whether the prevalence of vacuolating cytotoxin production differed among Helicobacter pylori isolates obtained from patients with chronic gastritis, gastric ulcer, or duodenal ulcer. We examined the vacuolating cytotoxin production of 114 clinical H. pylori isolates in rabbit gastic epi...

journal_title：Journal of gastroenterology

authors： Kodama K,Fujioka T,Ito A,Kubota T,Murakami K,Nasu M

更新日期：1996-11-01 00:00:00

abstract：BACKGROUND:This study examined the association of cholelithiasis post-cholecystectomy with subsequent cancers and evaluated the risk of cancer in patients with both cholelithiasis and cholecystectomy. METHODS:The Taiwanese National Health Insurance Research Database was used to identify 15545 newly diagnosed cholelith...

journal_title：Journal of gastroenterology

authors： Chen YK,Yeh JH,Lin CL,Peng CL,Sung FC,Hwang IM,Kao CH

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Rice extract has been shown to protect gastric mucosa from stress-induced damage. In this study, the antibiotic effect and the anti-inflammatory effect of orally administered aqueous rice extract on Helicobacter pylori infection and H. pylori-induced gastritis, respectively, in Mongolian gerbils were investi...

journal_title：Journal of gastroenterology

authors： Murakami M,Ota H,Sugiyama A,Ishizone S,Maruta F,Akita N,Okimura Y,Kumagai T,Jo M,Tokuyama T

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:The remnant stomach corresponds to the gastric cardia, but is exposed to a completely different environment. The present study was performed to investigate the role of Epstein-Barr virus (EBV) infection in patients with gastric remnant carcinoma (GRC). METHODS:Clinicopathological features, gastritis, and in...

journal_title：Journal of gastroenterology

authors： Kaizaki Y,Hosokawa O,Sakurai S,Fukayama M

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:The precise pathogenic mechanism of nonsteroidal antiinflammatory drug-induced small intestinal injury is still unknown. In the present study, we investigated the mechanism by which indomethacin induced mucosal injury by using an in vitro model of small intestine. METHODS:The colon cancer cell line Caco-2, ...

journal_title：Journal of gastroenterology

authors： Omatsu T,Naito Y,Handa O,Hayashi N,Mizushima K,Qin Y,Hirata I,Adachi S,Okayama T,Kishimoto E,Takagi T,Kokura S,Ichikawa H,Yoshikawa T

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND/AIMS:King's College Hospital (KCH) criteria and the model for end-stage liver disease (MELD) score are useful and widely-employed prognostic markers for acute liver failure (ALF). We previously reported that liver atrophy is an important prognostic factor for ALF. The aim of the present study was to assess t...

journal_title：Journal of gastroenterology

authors： Yamagishi Y,Saito H,Ebinuma H,Kikuchi M,Ojiro K,Kanamori H,Tada S,Horie Y,Kato S,Hibi T

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:It is controversial whether patients with gastric marginal zone lymphomas of mucosa associated lymphoid tissue (MALT) have higher risk of second malignancies. The aim of this study was to define the risk of second malignancies in these patients. METHODS:We analyzed prospective follow-up data of 146 consecut...

journal_title：Journal of gastroenterology

authors： Tajika M,Matsuo K,Ito H,Chihara D,Bhatia V,Kondo S,Tanaka T,Mizuno N,Hara K,Hijioka S,Imaoka H,Matsumoto K,Nakamura T,Yatabe Y,Yamao K,Niwa Y

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVE:Recently, guidelines for the treatment and prevention of ulcers induced by non-steroidal anti-inflammatory drugs (NSAIDs) were established. This study investigated the association between the current adherence to the guidelines and the incidence of gastric mucosal lesions caused by NSAIDs. METHODS:This study...

journal_title：Journal of gastroenterology

authors： Tsumura H,Fujita T,Tamura I,Morita Y,Yoshida M,Toyonaga T,Mukai H,Inokuchi H,Kutsumi H,Azuma T

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Gastric marker mucins (MUC5AC and MUC6) and intestinal marker molecules (MUC2 and CD10) have been used to determine the cell lineage of epithelial cell of gastric carcinoma (GC). METHODS:To clarify the characteristics of Epstein-Barr virus (EBV)-associated GC, 18 cases were immunohistochemically evaluated a...

journal_title：Journal of gastroenterology

authors： Barua RR,Uozaki H,Chong JM,Ushiku T,Hino R,Chang MS,Nagai H,Fukayama M

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:Combination therapy of intravenous hepatitis B immunoglobulin (ivHBIG) and nucleos(t)ide (NA) analogues is the best post-liver transplantation (LT) prophylactic measure for hepatitis B virus (HBV). However, to reduce the long-term drawbacks of ivHBIG, we evaluated the efficacy of sequential entecavir (ETV) m...

journal_title：Journal of gastroenterology

authors： Yi NJ,Choi JY,Suh KS,Cho JY,Baik M,Hong G,Lee KW,Kim W,Kim YJ,Yoon JH,Lee HS,Kim DG

更新日期：2013-12-01 00:00:00

abstract：:A new triple therapy using a proton pump inhibitor and two antibiotics shows high efficiency against Helicobacter pylori infection. The aim of this study was to determine the optimal dose and duration of lansoprazole (LA) administration in combination with amoxicillin (AMPC) and metronidazole (MNZ). A total of 91 pati...

journal_title：Journal of gastroenterology

authors： Nishikawa K,Sugiyama T,Ishizuka J,Kudo T,Komatsu Y,Katagiri M,Sukegawa M,Kagaya H,Kudo M,Kato M,Takeda H,Toyota J,Asaka M

更新日期：1999-01-01 00:00:00