A model of global forebrain ischemia/reperfusion in the awake rat.

abstract：:In addition to its possible role as a replacement source in CNS degenerative diseases, neural transplantation may be used to augment the normal production of neuroactive substances. Our laboratory at the University of Illinois at Chicago has shown, in both acute and chronic pain models, that transplantation of adrenal...

journal_title：Neurological research

authors： Pappas GD,Lazorthes Y,Bès JC,Tafani M,Winnie AP

更新日期：1997-02-01 00:00:00

abstract：:Objective: Remote limb ischemic postconditioning (RIPostC) protects the brain from damage induced by transient focal ischemia/reperfusion. However, the underlying mechanism remains unclear. Methods: RIPostC induced by 10 min of occlusion and another 10 min releasing of blood flow for three cycles in the hind limbs was...

journal_title：Neurological research

authors： Liu C,Yang J,Zhang C,Geng X,Zhao H

更新日期：2019-01-01 00:00:00

abstract：:The purpose of the present study was to examine the effect of nilvadipine (a dihydropyridine-type calcium entry blocker) on the cerebral circulation, experimental models of cerebral ischemia were used to measure abrupt changes in the cortical cerebral blood flow (CBF) at the 'penumbra' (the boundary region between the...

journal_title：Neurological research

authors： Tanaka R,Miyasaka Y,Maruyama S,Nagai S,Fujii K

更新日期：1996-08-01 00:00:00

abstract：:Although radiation injuries to the brain are well documented, immediate early histological changes in the brain remain to be defined. The present study characterizes glial injury provoked in adult rat white matter within 24 h after a single irradiation of the whole brain (10 or 20 Gray). Irradiated brains were histolo...

journal_title：Neurological research

authors： Kurita H,Kawahara N,Asai A,Ueki K,Shin M,Kirino T

更新日期：2001-12-01 00:00:00

abstract：OBJECTIVE:To investigate the clinical application of adjuvant coiling techniques in treating anterior-circulation wide-necked aneurysms. METHODS:Over 4·5 years, 93 anterior-circulation wide-neck aneurysms in 81 patients were treated with different endovascular techniques: balloon-assisted, stent-assisted, and double-m...

journal_title：Neurological research

authors： Pan J,Xiao F,Szeder V,Yan M,Fan W,Gu J,He L,Zhan R

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVES:Progesterone modulates dopamine (DA) release in corpus striatum. Our objective was to evaluate the effect of the i.c.v injection of the neurosteroid allopregnanolone (ALL), a progesterone metabolite on dopaminergic activity in the corpus striatum of rats under different gonadal hormonal conditions. METHODS:...

journal_title：Neurological research

authors： Laconi MR,Reggiani PC,Penissi A,Yunes R,Cabrera RJ

更新日期：2007-09-01 00:00:00

abstract：OBJECTIVES:This study sought to compare the atherosclerotic plaque burden between middle cerebral artery (MCA) and extracranial carotid artery (ECA) in ischemic stroke patients using high-resolution, black-blood (HR BB) MRI and to investigate the relationship between plaque burden found in both arteries and stroke seve...

journal_title：Neurological research

authors： Cao Y,Sun Y,Zhou B,Zhao H,Zhu Y,Xu J,Liu X

更新日期：2017-04-01 00:00:00

abstract：:This paper describes a test prototype for precision robot-assisted surgery using a hexapod operating robot and a movable operating cockpit for tactile feedback. The objective of the work described is twofold: 1, to evaluate the use of hexapod robots for precisely manipulating endoscopes and surgical instruments in sub...

journal_title：Neurological research

authors： Urban V,Wapler M,Weisener T,Schönmayr R

更新日期：1999-01-01 00:00:00

abstract：OBJECTIVE:Spinal cord injury (SCI) causes muscle atrophy, which is particularly severe, due to inability to perform tetanic contractions, when lower motor neurons (LMN) are involved. We performed a longitudinal study in 25 Europeans suffering from complete conus cauda syndrome from 0.7 to 8.7 years comparing functional...

journal_title：Neurological research

authors： Kern H,Carraro U,Adami N,Hofer C,Loefler S,Vogelauer M,Mayr W,Rupp R,Zampieri S

更新日期：2010-02-01 00:00:00

abstract：:A new suction device for microneurosurgery is presented. A surgical cottonoid is covered with a polyethylene film so that vacuum power is maintained throughout the length of the cottonoid. One end is connected to a vacuum pump via a plastic tube. Five to 10 mm of the surgical cottonoid are exposed for suctioning at th...

journal_title：Neurological research

authors： Sakatani K,Zuo H

更新日期：1998-09-01 00:00:00

abstract：OBJECTIVE:Neurovascular ultrasound (nUS) is widely used as a screening and monitoring tool in patients with spontaneous cervical artery dissection (sCAD). The aim of the study was to describe the sonographical course of the affected arteries in patients with a MRI-proven sCAD by repetitive nUS. METHODS:Thirty-seven co...

journal_title：Neurological research

authors： Sengelhoff C,Nebelsieck J,Nassenstein I,Maintz D,Nabavi DG,Kuhlenbaeumer G,Ringelstein EB,Dittrich R

更新日期：2008-09-01 00:00:00

abstract：:More reliable prediction of outcome would be helpful for clinicians who treat severely head-injured patients. To determine if neural network modeling would improve outcome prediction compared with standard logistic regression analysis and to determine if data available 24 h after severe head injury allows better predi...

journal_title：Neurological research

authors： Lang EW,Pitts LH,Damron SL,Rutledge R

更新日期：1997-06-01 00:00:00

abstract：OBJECTIVE:Current chemotherapy treatments available for treating high-grade brain tumors, Temozolomide (TMZ) or Bevacizumab (BEV), not only have specific anti-tumor mechanisms, but also have an effect on mitochondria. However, effects of both drugs on mitochondria isolated from human brain tumors have not been thorough...

journal_title：Neurological research

authors： Nanegrungsunk D,Apaijai N,Yarana C,Sripetchwandee J,Limpastan K,Watcharasaksilp W,Vaniyapong T,Chattipakorn N,Chattipakorn SC

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Ischemic stroke is one of the most common causes of death worldwide. Early and accurate prediction of outcome in acute ischemic stroke (AIS) is important and influences risk-optimized therapeutic strategies. We investigated the changes in high-sensitivity C-reactive protein (Hs-CRP) and homocysteine (HCY) le...

journal_title：Neurological research

authors： Tu WJ,Zhao SJ,Liu TG,Yang DG,Chen H

更新日期：2013-11-01 00:00:00

abstract：OBJECT:The pathologies resulting from traumatic brain injury (TBI) have been thoroughly studied, but rarely have the effects of bleeding and coagulation in the early stage of TBI been considered. In this study, we investigated the effects of topical Surgiflo® application on brain injury in experimental TBI mice using S...

journal_title：Neurological research

authors： Guo D,Li D,Li J,Li Y,Hu X,Guan F,Yang B

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVE:In order to test for mechanisms of whole brain radio therapy side effects and possible neuroprotective measures, a rodent model is desirable. In many models, a high single dose of 8-20 Gray (Gy) of whole brain irradiation is used. These experimental radiation protocols do not closely reflect the clinical situ...

journal_title：Neurological research

authors： Semmler A,Garbe S,Moskau S,Frisch C,Eter N,Schlegel U,Linnebank M

更新日期：2013-05-01 00:00:00

abstract：:Ahead of Print article withdrawn by publisher. ...

journal_title：Neurological research

authors： Ma CX,Yin WN,Cai BW,He M,Wu J,Wang JY,Zeng Y,Ding JL,You C

更新日期：2009-08-21 00:00:00

abstract：:We studied brain temperature and the effect of mild hypothermia in 58 patients after severe head injury (SHI). Brain tissue oxygen tension (ptiO2), carbon dioxide tension (ptiCO2), tissuie pH (pHti) and temperature (T.br) were measured using a multiparameter probe. Microdialysis was performed to measure glucose, lacta...

journal_title：Neurological research

authors： Soukup J,Zauner A,Doppenberg EM,Menzel M,Gilman C,Bullock R,Young HF

更新日期：2002-03-01 00:00:00

abstract：OBJECTIVE:Glutamate antagonists are very attractive drugs in laboratory works to protect neural tissue against ischemia. In this work, the effects of magnesium, MK-801 and combination of magnesium and MK-801 on blood-brain barrier (BBB) and brain edema after experimentally induced traumatic brain injury are evaluated. ...

journal_title：Neurological research

authors： Imer M,Omay B,Uzunkol A,Erdem T,Sabanci PA,Karasu A,Albayrak SB,Sencer A,Hepgul K,Kaya M

更新日期：2009-11-01 00:00:00

abstract：:Monitoring of regional cerebral oxygen saturation (r. cereb. O2 satn.) was carried out continuously in 12 healthy subjects (mean age 35.2 +/- 4.4 years; range 26-41 years; 4 women, 8 men), prior to, during and following acupuncture. Measurements were obtained with the INVOS 3100 cerebral oximeter (Somanetics Corp., Tr...

journal_title：Neurological research

authors： Litscher G,Schwarz G,Sandner-Kiesling A,Hadolt I,Eger E

更新日期：1998-01-01 00:00:00

abstract：:Excessive entry of Ca2+ into injured cochlear neurons activates various Ca(2+)-activated enzymes and subsequent spiral ganglion cell death. Therefore, preventing intracellular calcium overload by using Ca2+ channel antagonists may become an important countermeasure to spiral ganglion cell death. We experimentally inve...

journal_title：Neurological research

authors： Sekiya T,Yagihashi A,Asano K,Suzuki S

更新日期：2002-12-01 00:00:00

abstract：:Electrical stimulation of peripheral nerves can be used to cause muscle contraction, to activate reflexes, and to modulate some functions of the central nervous system (neuromodulation). If applied to the spinal cord or nerves controlling the lower urinary tract, electrical stimulation can produce bladder or sphincter...

journal_title：Neurological research

authors： Jezernik S,Craggs M,Grill WM,Creasey G,Rijkhoff NJ

更新日期：2002-07-01 00:00:00

abstract：:Objective: The protective effects of 2%-4% hydrogen gas in delayed encephalopathy after acute carbon monoxide poisoning (DEACMP) have been previously reported. This study aimed to assess the neuroprotective effects of high concentration hydrogen (HCH) on DEACMP.Methods: A total of 36 male Sprague-Dawley rats were divi...

journal_title：Neurological research

authors： Shen M,Zheng Y,Zhu K,Cai Z,Liu W,Sun X,Liu J,Zhu D

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:The present study was undertaken to evaluate whether resveratrol (RSV) modulates membrane lipid composition, as well as on ganglioside profile in ischemia/reperfusion injury. METHODS:Global cerebral ischemia was induced by four-vessel occlusion for 10 minutes. RSV (30 mg/kg) or vehicle was intraperitoneally...

journal_title：Neurological research

authors： Simão F,Matté A,Breier AC,Kreutz F,Trindade VM,Netto CA,Salbego CG

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to characterize mouse neural stem cells (NSC) transduced by a multigenic lentiviral vector (LV) and stably express recombinant human nerve growth factor (rhNGF). We obtained NSC-derived cell lines which express human NGF in relevant amount to exploit their ability for therapeuti...

journal_title：Neurological research

authors： Cenciarelli C,Budoni M,Mercanti D,Fernandez E,Pallini R,Aloe L,Cimino V,Maira G,Casalbore P

更新日期：2006-07-01 00:00:00

abstract：OBJECTIVE:Leptin may be associated with cardiovascular disease. We tested to determine whether leptin is a marker for first-ever acute ischemic stroke (AIS) in a nested case-referent study. METHODS:Consecutive patients with first-ever AIS from May 2017 to December 2017 were included. Referents were matched for sex, ag...

journal_title：Neurological research

authors： Liu G,Dong M,Ma S,Fu L,Xiao Y,Zhong L,Geng J

更新日期：2019-02-01 00:00:00

abstract：:Neural stem cells (NSCs) are self-renewable, multipotential cells capable of differentiating into the three major neural cell types, but the mechanisms which regulate their development are not fully understood. Both basic fibroblast growth factor (bFGF) and epidermal growth factor (EGF) promote the proliferation of NS...

journal_title：Neurological research

authors： Reimers D,López-Toledano MA,Mason I,Cuevas P,Redondo C,Herranz AS,Lobo MV,Bazán E

更新日期：2001-09-01 00:00:00

abstract：OBJECTIVES:In the clinical set, autologus nerve grafts are the current option for reconstruction of nerve tissue losses. The length of the nerve graft has been suggested to affect outcomes. Experiments were performed in the rat in order to test this assumption and to detect a possible mechanism to explain differences i...

journal_title：Neurological research

authors： Bertelli JA,Taleb M,Mira JC,Ghizoni MF

更新日期：2005-09-01 00:00:00

abstract：:Anoxic depolarization (AD) is one of the major physiological characteristics in the ischemic core. The effect of mild hypothermia on the appearance of AD and subsequent brain injury following profound ischemia is studied to evaluate the protective mechanism of hypothermia against severe ischemia. Sprague-Dawley rats w...

journal_title：Neurological research

authors： Kaminogo M,Ichikura A,Onizuka M,Takahata H,Matsuo Y,Kitagawa N,Shibata S

更新日期：1999-10-01 00:00:00

abstract：OBJECTIVE:In this clinical case-control study, we investigated statin treatment in stroke patients on a range of inflammatory effectors in peripheral blood. We focus on RhoA GTPase and its downstream effectors as a future inflammatory target in stroke treatment. METHODS:Data from 10 patients already on statins at stro...

journal_title：Neurological research

authors： Schultz NEØ,Hasseldam H,Rasmussen RS,Vindegaard N,McWilliam O,Iversen HK,Johansen FF

更新日期：2019-04-01 00:00:00