Cross cultural differences in health related quality of life in adolescents with cystic fibrosis.

Abstract:

PURPOSE:Quality of Life (QoL) is an important outcome measure in health care and pharmacological trials. The trend towards multinational clinical trials may be problematic because it is unclear as to whether, or to what extent, QoL-measures are comparable across cultures. This study compared QoL between English and German adolescents with Cystic Fibrosis (CF) and their healthy peers. METHOD:The study comprised a cross-sectional design. The English subjects formed two groups; 58 adolescents with CF and 49 healthy controls. The German subjects consisted of 26 adolescents with CF and 75 healthy controls. Quality of life was measured using the English and German versions of the SF-36. Demographic (age and gender) and clinical data (FEV1% predicted and BMI) were also recorded. RESULTS:The English and German CF groups had similar age-adjusted lung function and body mass index. Both the English CF and control groups reported a poorer quality of life than their respective German counterparts across several domains of the SF-36. These were limitations in activities due to physical health problems and emotional difficulties, social functioning, energy and vitality and pain. CONCLUSIONS:The differences in quality of life between English and German adolescents with CF appear to be either culturally determined or due to idiosyncrasies in the translations of the SF-36. rather than a consequence of their disease or its management.

journal_name

Disabil Rehabil

authors

Abbott J,Baumann U,Conway S,Etherington C,Gee L,Von Der Schulenburg JM,Webb K

doi

10.1080/09638280110072913

subject

Has Abstract

pub_date

2001-12-15 00:00:00

pages

837-44

issue

18

eissn

0963-8288

issn

1464-5165

journal_volume

23

pub_type

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