Abstract:
:The human papillomavirus (HPV) E6 protein is one of three oncoproteins encoded by the virus. It has long been recognized as a potent oncogene and is intimately associated with the events that result in the malignant conversion of virally infected cells. In order to understand the mechanisms by which E6 contributes to the development of human malignancy many laboratories have focused their attention on identifying the cellular proteins with which E6 interacts. In this review we discuss these interactions in the light of their respective contributions to the malignant progression of HPV transformed cells.
journal_name
Oncogenejournal_title
Oncogeneauthors
Mantovani F,Banks Ldoi
10.1038/sj.onc.1204869subject
Has Abstractpub_date
2001-11-26 00:00:00pages
7874-87issue
54eissn
0950-9232issn
1476-5594journal_volume
20pub_type
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