Abstract:
:As a continuation of our previous work, where we have demonstrated that in chronic otitis media the picture in the submucosa-bone marginal zone is dominated by capillary proliferation and occurrence of a mononuclear, histiocyte-like cell containing lysosome-like cytoplasmatic bodies, we now report the presence of considerable activity of acid phosphatase in close relation to the eroded bone. The activity was localized both extracellularly, spread along the bony surface, as well as intracellularly in mononuclear, histiocyte-like cells. The acid phosphatase is the "marker" enzyme for lysosomes, and cells with these lysosomes guarantee the presence of enzymatic activity capable of attacking bone collagen. It is difficult to avoid the conclusion that the lysosomes and their enzymes are directly involved in the processes of bone resorption.
journal_name
Acta Otolaryngoljournal_title
Acta oto-laryngologicaauthors
Thomsen J,Bretlau P,Kristensen HKdoi
10.3109/00016487509124704subject
Has Abstractpub_date
1975-05-01 00:00:00pages
400-8issue
5-6eissn
0001-6489issn
1651-2251journal_volume
79pub_type
杂志文章abstract:CONCLUSION:Chemosensory event-related potentials (CSERPs) were identified in all measurements using the 20 s and the 10 s inter-stimulus interval (ISI) protocol, reducing the recording time to 75% or 57% compared with the standard protocol. A possible explanation for the rising CSERP amplitudes by shortening the ISI in...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016480802644605
更新日期:2009-11-01 00:00:00
abstract::Cisplatin ototoxicity is known to involve mainly the organ of Corti. Outer hair cells (OHCs). especially in the basal turn, are preferentially involved. One possible mechanism of ototoxicity might be alteration of the antioxidant system causing an increase in free radicals. It has been demonstrated that heat shock pro...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/000164800750000793
更新日期:2000-03-01 00:00:00
abstract::Conventional (visual) analysis of EMG was compared to a computerized quantitative method (turns/amplitude). Ten patients with a clinical history of peripheral nerve lesion were examined in order to investigate whether quantitative analysis of EMG increased the diagnostic sensitivity of peripheral nerve lesions to the ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489409126023
更新日期:1994-01-01 00:00:00
abstract::The fear of destroying an anticipated growth centre has, with time, induced the postponement of nasal septal operations until adult age. Underdevelopment of the nose and middle face is otherwise believed to be the long-term result. In order to test this hypothesis, subepichondrial surgery was performed in growing dome...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488509104794
更新日期:1985-09-01 00:00:00
abstract:CONCLUSION:Each of eight patients with bilateral microtia and atresia underwent bilateral reconstruction of the auricles and external auditory canals and were fitted bilateral canal-type hearing aids in the operated ears to replace a bone conduction hearing aid. The ability to discriminate inter-aural intensity differe...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2016.1249947
更新日期:2017-04-01 00:00:00
abstract:CONCLUSION:Bilateral electric acoustic stimulation (EAS) effectively improved speech perception in noise and sound localization in patients with high-frequency hearing loss. OBJECTIVE:To evaluate bilateral EAS efficacy of sound localization detection and speech perception in noise in two cases of high-frequency hearin...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2014.951453
更新日期:2015-02-01 00:00:00
abstract::A case-control design was used to assess eye-head-trunk coordination for community-dwelling elders performing a stand-walk task. Eighteen elders with a high risk of falling were matched to 18 subjects with low risk on the basis of age, living status (living alone or with someone) and category of residence (independent...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480152583656
更新日期:2001-09-01 00:00:00
abstract:CONCLUSIONS:Flat-panel cone-beam computed tomography (CBCT) is able to assess the trajectory of the implanted cochlear implant (CI) array. This is essential to determine specific effects of electrode design and surgical innovations on outcomes in cochlear implantation. CBCT is a non-invasive approach yielding similar d...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2011.644805
更新日期:2012-04-01 00:00:00
abstract::We studied the pathological changes in the temporal bone and brainstem, with particular attention to the autolysis of red blood cells in and around the blood vessels, in six cases of brainstem death determined by auditory brainstem responses (ABRs). Our findings showed that the cochlea, the visceral organs and the spi...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489509139287
更新日期:1995-03-01 00:00:00
abstract:CONCLUSION:PET-CT scans seem to be sufficient to rule out residual tumour at the primary site. Patients with positive or equivocal PET findings should be scheduled for endoscopy with biopsy or a second PET-CT scan. OBJECTIVES:Assessment of remission at the primary site, in patients treated with organ preservation ther...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2014.895038
更新日期:2014-06-01 00:00:00
abstract:CONCLUSION:The results of this study suggest that treatment with radical scavengers has the potential to become an effective new therapy for age-related hearing loss. OBJECTIVE:To assess the efficacy of treatment with radical scavengers for age-related hearing loss. SUBJECTS AND METHODS:Rebamipide (300 mg/day), alpha...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480802008215
更新日期:2009-01-01 00:00:00
abstract::In 6 pigs a bronchoscopical resection of the tracheal mucosa was performed using CO2-laser on one side, and an electric high-frequency cutting loop (ECL) on the other. The pigs were sacrificed 3 months later. On macroscopic examination the tracheal mucosa appeared almost normal on the laser-resected side, while severe...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488909127514
更新日期:1989-03-01 00:00:00
abstract::Four groups of guinea pigs received different doses of cis-platinum. SEM and TEM showed a direct relation between the dose and the damage. The first row of OHC is the first one to be damaged. The IHC are more resistant than the OHC. The pattern of destruction is similar to the one produced by the aminoglucoside antibi...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488509108921
更新日期:1985-03-01 00:00:00
abstract::Preyer's reflex, the elicitation of startle response to auditory stimuli, has been widely used for the evaluation of hearing in rodents and other animals. Surprisingly, however, the sensitivity and specificity of Preyer's reflex in the assessment of hearing has not been adequately studied. The aim of this study was to...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:
更新日期:2001-07-01 00:00:00
abstract:OBJECTIVES:Hearing loss after spinal anesthesia has been reported to be related to the transmission of a reduced subarachnoid pressure to the inner ear via the cochlear aqueduct due to loss of spinal fluid. However, there are also some controversies related to this phenomenon, which require systematic investigation. M...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480410017143
更新日期:2004-12-01 00:00:00
abstract::The trachea whole organ perfusion technique was used to study the effect of tumor necrosis factor alpha (TNF alpha) and interleukin-1 alpha (IL-1 alpha) on the adherence of otitis media pathogen Streptococcus pneumoniae (Spn) type 6A. Tracheas were removed from chinchillas and divided equally. One-half trachea was act...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489950181981
更新日期:1999-01-01 00:00:00
abstract::Juvenile nasopharyngeal angiofibroma is a disease afflicting mainly adolescent males. The lesion is benign but characterized by local aggressive growth. In advanced cases the tumour may extend intracranially. In this study 18 cases of juvenile nasopharyngeal angiofibroma were investigated. Tumour extension was assesse...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488809119456
更新日期:1988-01-01 00:00:00
abstract::The experimental use of jejunal free grafts with microvascular anastomosis in the head and neck region has been reported in pharyngeal and esophageal reconstruction. Lack of a suitable animal model has limited basic research for cutaneous or myocutaneous microvascular techniques. This investigation upon appropriate gr...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488409107574
更新日期:1984-09-01 00:00:00
abstract:CONCLUSIONS:1. The principle of bilateral symmetry depends on the chordal cartilage that is the keystone in cranial base ossification in rats and humans, due to its anatomical situation and for the production of the chordin protein that regulates the bone morphogenetic protein BMP-7. 2. In humans and in rats, foramen l...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2011.642814
更新日期:2012-04-01 00:00:00
abstract::The expression of vascular cell adhesion molecule-1 (VCAM-1), alpha4-integrin and L-selectin was dynamically observed using an immunohistochemical approach during labyrinthitis induced by inoculation of keyhole limpet hemocyanin into the scala tympani of animals that had been systemically sensitized to it. At the same...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/000164800750000414
更新日期:2000-08-01 00:00:00
abstract:CONCLUSION:A simple measuring box to determine lip-shift angle and eye-width narrowing offered simultaneous and objective data on outcome dysfunction. The method is as easy as visual approaches. The method is objective and as easy as visual access. It is practical for routine clinical use in any clinic. OBJECTIVES:The...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2011.626793
更新日期:2012-01-01 00:00:00
abstract:CONCLUSION:Speech thresholds measured using Cantonese Hearing in Noise Test (CHINT) and cortical evoked response audiometry (CERA) thresholds were highly correlated with pure-tone behavioral results. Both tests are considered to provide good estimates of hearing thresholds and can be employed to confirm the degree of h...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480701642189
更新日期:2008-06-01 00:00:00
abstract::Olfactory and respiratory epithelia was prepared for thin-section and freeze-fracture replicas, and were investigated using electron microscopy. Three cell types were identified in the olfactory epithelium: olfactory receptor neurons (ORN), sustentacular cells (SC) and basal cells (BC); and respiratory epithelial cell...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488909125526
更新日期:1989-09-01 00:00:00
abstract::Intracellular calcium concentrations ([Ca2+]i) in type I cochlear spiral ganglion cells (SGCs) of the guinea pig were measured by digital imaging microscopy and the Ca(2+)-sensitive dye Fura-2. Extracellular ATP induced elevation of [Ca2+]i in type I SGCs in a concentration-dependent manner. The ATP-induced elevation ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489709113435
更新日期:1997-07-01 00:00:00
abstract:OBJECTIVE:Multiple patches of atrophy have been reported in the stria vascularis (SV) in elderly persons with presbycusis The aim of this study was to investigate the correlation between sensorineural hearing loss and this strial condition. MATERIALS AND METHODS:We established a new animal model comprising two small l...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/0001648021000028131
更新日期:2003-04-01 00:00:00
abstract::Using electron microscopy and GABA immunohistochemistry we evaluated the effects on human embyronic organ of Corti tissue culture of exposure to the ototoxic aminoglycoside antibiotic neomycin at a dose of 1 mM for 48 to 96 hrs. Neomycin induces the formation of multilamellar myeloid structures. These lesions, found o...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489609137929
更新日期:1996-11-01 00:00:00
abstract::Dysphagia is a common presenting complaint in otolaryngology practice, and there are many causes. Forestier syndrome is a rare cause of dysphagia. It is also known as diffuse idiopathic skeletal hyperostosis (DISH) syndrome or vertebral ankylosing hyperostosis. Forestier syndrome consists of anterolateral perivertebra...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480500504192
更新日期:2006-07-01 00:00:00
abstract::The embryonic development of the crista ampullaris of the CBA/CBA mouse was followed both in organ culture of explanted inner ears of the 16th gestational day and in vivo from the 16th gestational day until the 21st day, an age corresponding to birth. Cytodifferentiation of the sensory epithelium of the crista ampulla...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488309132868
更新日期:1983-07-01 00:00:00
abstract::The input from fore- and hindlimbs to the vestibular nuclear complex (VNC) was investigated in awake cats. Electrical stimulus was given to the sciatic, radial and vestibular nerves bilaterally and single unit responses were recorded in the VNC with extracellular technique. The position of the microelectrode was histo...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487909126395
更新日期:1979-01-01 00:00:00
abstract:CONCLUSION:Coexistent migraine affects relevant clinical features of patients with Ménière's disease (MD). OBJECTIVE:Epidemiological studies have shown an association between migraine and MD. We sought to determine whether the coexistence of migraine affects any clinical features in patients with MD. PATIENTS AND MET...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480701242469
更新日期:2007-12-01 00:00:00