Seeing is believing: GFP transgenics illuminate synapse elimination.

Abstract:

:Synapses are lost during developmental synapse elimination. Until now, it has been impossible to follow elimination in the entirety of any neuron's branches and synapses. Using transgenic mice in which one or two of a muscle's motoneurons express variants of GFP, Keller-Peck et al. show in this issue of Neuron that elimination occurs asynchronously by local competitive interactions at each synaptic site, apparently independent of events elsewhere in the neuron's terminal field.

journal_name

Neuron

journal_title

Neuron

authors

Thompson WJ

doi

10.1016/s0896-6273(01)00380-4

subject

Has Abstract

pub_date

2001-08-16 00:00:00

pages

341-2

issue

3

eissn

0896-6273

issn

1097-4199

pii

S0896-6273(01)00380-4

journal_volume

31

pub_type

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