Abstract:
INTRODUCTION:Visual hallucinosis occurs frequently amongst patients with dementia and there is some evidence of an association between hallucinosis and impaired visual function. This study examined the association between objectively rated visual acuity, ambient illumination levels and hallucinosis in patients with dementia. METHODS:Thirty dementia patients with visual hallucinosis plus 30 non-hallucinating dementia patients were recruited from referrals to community mental health teams in Leicestershire. Data were collected by means of a carer interview (including the Neuro-Psychiatric Inventory (NPI) and Clinical Dementia Rating Scale (CDR)), patient assessment (including Mini-Mental State Examination (MMSE) and measures of corrected visual acuity) and photometric assessment of the room most frequently occupied by the subject. RESULTS:Hallucinators and non-hallucinators did not differ significantly in respect of age, cognitive status or global dementia severity. Fifty per cent of hallucinators had a Snellen visual acuity of 6/24 or worse compared with 27% of non-hallucinators. Comparison of LogMAR transformed values for distance (Snellen chart) and near-vision (Sussex test-types) revealed significantly worse visual acuity for hallucinators on both measures (Mann-Whitney p < 0.05 and p < 0.01, respectively). Ambient illumination in the centre of the room under conditions of natural plus artificial lighting was significantly lower for hallucinating subjects than for non-hallucinators (median values 200 versus 345 Lux respectively; Mann-Whitney p < 0.05). CONCLUSION:These results are consistent with previous findings suggesting an association between visual hallucinations and poor visual acuity in patients with dementia, and introduce environmental illumination as another possible aetiologically relevant factor. Interventions aimed at improving visual function in this patient group now require evaluation.
journal_name
Int J Geriatr Psychiatryjournal_title
International journal of geriatric psychiatryauthors
Murgatroyd C,Prettyman Rdoi
10.1002/gps.426subject
Has Abstractpub_date
2001-07-01 00:00:00pages
709-13issue
7eissn
0885-6230issn
1099-1166journal_volume
16pub_type
杂志文章abstract:BACKGROUND:Many studies have sought to determine the predictors of institutionalization of patients with dementia. Such studies, performed in developed western societies, have come to various conclusions which may not be supported in an East Asian culture such as that found in Korea. OBJECTIVES:This study aimed to det...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/gps.494
更新日期:2002-02-01 00:00:00
abstract:BACKGROUND:The burgeoning field of gerontechnology, which is the interdisciplinary field of applying technology to ageing issues, has focused primarily on "active ageing" and maintaining independence for older adults. To date, there has been less focus on people who develop dementia. Here, we argue for the field of ger...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/gps.4906
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND:Cognitive screening instruments are either too long for routine clinical use or not sensitive to distinguish mild cognitive impairment (MCI) from normal cognition (NC) or dementia. OBJECTIVE:To evaluate the sensitivity and specificity of the AB Cognitive Screen (ABCS) and its subtests with a view to improvi...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/gps.1659
更新日期:2007-03-01 00:00:00
abstract:OBJECTIVE:To compare performance of patients with mild-moderate Alzheimer's disease (AD) and vascular dementia (VaD) on tests of executive functioning and working memory. METHODS:Patients with AD (n = 76) and VaD (n = 46) were recruited from a memory clinic along with dementia free participants (n = 28). They underwen...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/gps.2375
更新日期:2010-06-01 00:00:00
abstract:OBJECTIVE:This study examined the association between a history of heavy alcohol use and smoking, presence of the apolipoprotein-E epsilon 4 allele (APOE epsilon4), and age of disease onset in a community dwelling sample of 685 Alzheimer's disease (AD) patients spanning three ethnic groups. DESIGN:Cross-sectional stud...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/gps.2372
更新日期:2010-05-01 00:00:00
abstract:OBJECTIVES:To investigate the effect of cobalamin/folate supplementation on cognitive function in elderly patients with dementia. METHOD:The cobalamin/folate status of the patients was evaluated by measuring plasma homocysteine, serum methylmalonic acid, serum cobalamin and blood folate. Thirty-three patients were stu...
journal_title:International journal of geriatric psychiatry
pub_type: 临床试验,杂志文章
doi:10.1002/gps.388
更新日期:2001-06-01 00:00:00
abstract:OBJECTIVE:To evaluate variables associated with quality of life (QOL) in dementia residents in a long-term care facility using a recently standardized and validated dementia-specific QOL scale (ADRQL). METHOD:A cross-sectional, case-control design was employed using validated scales to assess dementia-related symptoma...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/(sici)1099-1166(200002)15:2<181::aid-gps96
更新日期:2000-02-01 00:00:00
abstract:OBJECTIVE:To evaluate the prevalence, clinical features, and comorbidities of restless legs syndrome (RLS) among psychogeriatric patients in an out-patient clinical setting. METHODS:Cross-sectional study of a sample of 100 non-demented psychogeriatric outpatients that were assessed for the presence of RLS using the Re...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/gps.2674
更新日期:2011-12-01 00:00:00
abstract:BACKGROUND:Depression frequently co-occurs with cognitive decline, but the nature of this association is unclear. We examined relations of late-life depressive symptom patterns to subsequent domain-specific cognitive changes. METHODS:Depressive symptoms were measured at up to 3 timepoints among 11,675 Nurses' Health S...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/gps.4618
更新日期:2017-12-01 00:00:00
abstract:OBJECTIVE:To examine the effectiveness of dementia programmes and report factors related to programme outcomes. To describe the characteristics which placed hostel residents at risk for nursing home placement and to measure changes in dependencies and impairments over 2 years. DESIGN:Longitudinal, quasi-experimental u...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/(sici)1099-1166(199702)12:2<173::aid-gps59
更新日期:1997-02-01 00:00:00
abstract:OBJECTIVE:Neuropsychiatric symptoms (NPs) affect almost all patients with Alzheimer disease (AD). Because of the complications associated with the pharmacological treatment, nonpharmacological treatment (such as physical activity) can be considered as an additional complementary treatment option for NPs. The aim of thi...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章,评审
doi:10.1002/gps.4962
更新日期:2019-09-01 00:00:00
abstract:OBJECTIVES:To investigate the efficacy of the chronic usage of the cholinesterase inhibitor rivastigmine in patients with dementia in the prevention of delirium in case of hospitalisation. DESIGN:Retrospective cohort study. SETTING:Non-geriatric wards of an 1120 bed general teaching hospital in s-Hertogenbosch, The N...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/gps.1138
更新日期:2004-07-01 00:00:00
abstract:OBJECTIVES:The objective of this study was to evaluate the effect of tumour necrosis factor-alpha inhibitors (TNF-αI) on Alzheimer's disease-associated pathology. DESIGN:A literature search of PubMed, Embase, PsychINFO, Web of Science, Scopus, and the Cochrane Library databases for human and animal studies that evalua...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/gps.4871
更新日期:2018-05-01 00:00:00
abstract:OBJECTIVES:The present cross-sectional study analyzed the prevalence and severity of depressive symptoms among patients with Alzheimer's disease (DAT), vascular dementia (VAD), and among the cognitively normal elderly. Putative risk factors contributing to depression were likewise evaluated. METHODS:Seventy-six DAT pa...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/gps.360
更新日期:2001-05-01 00:00:00
abstract:OBJECTIVE:To investigate patient predictors of response to treatment of Major Depressive Episode (MDE) in Alzheimer's disease (AD). METHODS:Forty-four outpatients with AD and MDE were randomized to receive either sertraline or placebo in a 12-week placebo-controlled, flexible-dose clinical trial after a one week singl...
journal_title:International journal of geriatric psychiatry
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/gps.1048
更新日期:2004-02-01 00:00:00
abstract:BACKGROUND:Neuropsychiatric symptoms (NPS) are a common feature of Alzheimer's disease (AD), resulting in particular AD endophenotypes. The common AD genetic risk factor apolipoprotein E (APOE) has been suggested underlying these AD endophenotypes. METHODS:APOE genotyping, a comprehensive geriatric assessment (CGA), a...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/gps.2644
更新日期:2011-10-01 00:00:00
abstract:OBJECTIVES:The objectives of this study are to explore the feasibility of a multicomponent intervention programme and to evaluate its impacts on behavioural and psychological symptoms of dementia (BPSD) and psychological health of caregivers. METHODS:Fifty-six community-dwelling people with dementia (PWD) and knee ost...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/gps.5191
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND:Vascular dementia (VaD) is associated with impairments in cognitive, motor, and functional domains. Patients with VaD display diverse cognitive and motor deficits, however, and relationships between these impairments and independent living abilities remain unclear. OBJECTIVES:The purpose of the present stud...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/gps.539
更新日期:2002-02-01 00:00:00
abstract:OBJECTIVE:Apathy is one of the most frequent symptoms of dementia, whose underlying neurobiology is not well understood. The objective was to analyze the correlations of apathy and its dimensions with gray and white matter damage in the brain of patients with advanced Alzheimer's disease (AD). METHODS:The setting of t...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/gps.4548
更新日期:2017-08-01 00:00:00
abstract::A study to estimate the prevalence of dementia in a rural population was conducted in a community located on the outskirts of Madras city in South India. Seven hundred and fifty elderly 60 years of age and older, selected using the cluster sampling technique, were interviewed using the Geriatric Mental State schedule ...
journal_title:International journal of geriatric psychiatry
pub_type: 社论
doi:10.1002/(sici)1099-1166(199707)12:7<702::aid-gps48
更新日期:1997-07-01 00:00:00
abstract:OBJECTIVES:This integrative review aimed to synthesize studies that investigated the effects of acupressure on sleep quality, depression, anxiety, and agitation in older people, and to describe the acupressure procedures and techniques applied in the included studies. METHODS:A literature search was conducted using el...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/gps.5031
更新日期:2019-03-01 00:00:00
abstract:OBJECTIVE:Although the evidence base for the use of antipsychotics in older people with schizophrenia is generally of low quality, it tends to support the use of atypical antipsychotics. Only limited information regarding longer term adherence to these apparently more effective drugs is available. The aim of this study...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1002/gps.2354
更新日期:2010-04-01 00:00:00
abstract:OBJECTIVE:Minor stroke is characterized by mild neurological functional impairment and relatively good outcome. Little is known about the association between post-stroke depression (PSD) and outcomes of minor stroke. The aim of this study was to investigate the association between PSD and disability and quality of life...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/gps.4353
更新日期:2016-04-01 00:00:00
abstract:OBJECTIVES:The number of older adults with severe mental health problems such as schizophrenia is likely to double in the next 20 years. The needs of this patient group change across the life course, but difficulties with social functioning persist into older age. Poorer social functioning is associated with poorer out...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/gps.5264
更新日期:2020-05-01 00:00:00
abstract:OBJECTIVE:Exposure to negative life events (NLEs) and neuroticism are associated with dementia. It is unknown whether neuroticism explains or modifies the association of NLEs with dementia in older Black and White Brazilians. METHODS:A total of 1747 decedents 65 years and older White and Black (11% Black and 23% Mixed...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/gps.5491
更新日期:2020-12-30 00:00:00
abstract:OBJECTIVES:To identify factors which may contribute to prolonged length of stay in an elderly psychiatric inpatient setting. DESIGN:Retrospective case note study. METHODS:A list of all patients over the age of 65 discharged from a private psychiatric hospital over a three-year period excluding those with a length of ...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/gps.463
更新日期:2001-10-01 00:00:00
abstract:BACKGROUND:Hoarding disorder (HD) is a chronic and debilitating psychiatric condition. Midlife HD patients have been found to have neurocognitive impairment, particularly in areas of executive functioning, but the extent to which this is due to comorbid psychiatric disorders has not been clear. AIMS/METHOD:The purpose...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/gps.3940
更新日期:2013-11-01 00:00:00
abstract::A common phenomenon in South-East Asia is ageing of the population. This article describes the various stages of development of psychogeriatrics in Hong Kong, Singapore, Malaysia, Thailand, Indonesia and the Philippines. It is only in the last few years that more systematic development of psychogeriatric services has ...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/(sici)1099-1166(199710)12:10<989::aid-gps6
更新日期:1997-10-01 00:00:00
abstract:BACKGROUND:Alzheimer's disease (AD) causes progressive loss of memory and disability, especially in older people. As worldwide population grows older, AD is responsible for an important social and economical burden in many nations. People suffering from AD may experience health-related stigma that influences their atti...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/gps.3903
更新日期:2013-09-01 00:00:00
abstract:INTRODUCTION:Little is known about the prevalence of impaired executive control function (ECF) in community dwelling elderly or minority populations. We have determined the prevalence of cognitive impairment and impaired ECF in a community dwelling Mexican American elderly population, and their associations with functi...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/gps.1185
更新日期:2004-10-01 00:00:00