Sex ratio in offspring of those affected by dioxin and dioxin-like compounds: the Yusho, Seveso, and Yucheng incidents.

Abstract:

:Sex ratios in the offspring of those affected by dioxins or dioxin-like compounds have been reported from Seveso, Italy and Yucheng, Taiwan. The sex ratio of live births in Yusho, Japan after a similar accidental massive exposure to polychlorinated biphenyls (PCBs) and polychlorinated dibenzofurans (PCDFs) in 1968 are reviewed. Data on all births among parents exposed to the compounds from 1968 to 1977 in Fukuoka and a region of Nagasaki, the two areas affected, are reported. In total there were 85 live births in those regions. The sex ratio was not significantly different from normal (0.513). To evaluate hormonal disrupting activity or effects on reproductive outcome by PCBs and PCDFs, a further investigation of sex in offspring of the Yusho victims, especially offspring of those who were younger than 19 years of age at the time of the Yusho incident, is needed.

journal_name

Occup Environ Med

authors

Yoshimura T,Kaneko S,Hayabuchi H

doi

10.1136/oem.58.8.540

subject

Has Abstract

pub_date

2001-08-01 00:00:00

pages

540-1

issue

8

eissn

1351-0711

issn

1470-7926

journal_volume

58

pub_type

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