Abstract:
STUDY OBJECTIVE:Factors influencing diastolic filling of the left ventricle may serve as critical determinants of both maximal cardiac output and oxygen uptake. This study was conducted to assess diastolic filling dynamics of the left ventricle during progressive upright cycle exercise in children. METHODS:Twelve boys aged 10 to 14 years underwent cycle testing with determination of transmitral flow velocities and pressure gradients as well as cardiac stroke volume using Doppler echocardiography. RESULTS:Estimated diastolic filling period shortened from 0.479 +/- 0.043 s at rest to 0.138 +/- 0.015 s at peak exercise. The peak and mean transmitral pressure gradient rose fourfold from rest to peak exercise. Mitral flow volume per beat rose by only 40% and remained stable beyond mild-to-moderate intensity work. CONCLUSIONS:Increases in transmitral pressure gradient with exercise may serve principally to augment velocity of ventricular filling with the progressively shortening diastolic time period.
journal_name
Chestjournal_title
Chestauthors
Rowland T,Mannie E,Gawle Ldoi
10.1378/chest.120.1.145subject
Has Abstractpub_date
2001-07-01 00:00:00pages
145-50issue
1eissn
0012-3692issn
1931-3543pii
S0012-3692(15)35806-2journal_volume
120pub_type
杂志文章相关文献
CHEST文献大全abstract::Residual volume (RV) was obtained by subtracting vital capacity from total lung capacity determined by the single breath helium dilution (TLCsb) to measure CO diffusing capacity in 2,680 subjects (8 to 64 years old) of a general population sample. There were 712 normal subjects (243 male and 469 female subjects) selec...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.102.4.1209
更新日期:1992-10-01 00:00:00
abstract::The echocardiographic appearance of fungal endocarditis of the aortic valve is described in a patient who subsequently died from this disease. In addition, the progressive growth of the vegetation on serial echocardiograms was recorded, and premature closure of the mitral valve was absent, notwithstanding perforation ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.70.2.300
更新日期:1976-08-01 00:00:00
abstract:BACKGROUND:The prevalence of COPD is estimated to 4 to 14%. According to the Global Initiative for Chronic Obstructive Lung Disease guidelines, COPD is divided into four stages. Patients with stage IV disease (very severe) have FEV1 < 30% of predicted values and/or respiratory insufficiency. The few studies that exist ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.130.3.666
更新日期:2006-09-01 00:00:00
abstract::To assess airway and lung parenchymal damage non-invasively in cystic fibrosis (CF), chest MRI has been historically out of the scope of routine clinical imaging due to technical difficulties such as the low proton density and respiratory and cardiac motion. However, technological breakthroughs have recently emerged t...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1016/j.chest.2020.12.008
更新日期:2020-12-17 00:00:00
abstract::We report a patient with situs inversus and ischemic heart disease who had myocardial revascularization with anastomosis of the right mammary artery to the anterior descending coronary artery. ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.94.4.886
更新日期:1988-10-01 00:00:00
abstract::There is now a new pathway and examination for sleep medicine, sponsored by the American Board of Internal Medicine, and a number of accredited sleep medicine fellowship programs through the Accreditation Council for Graduate Medical Education. This review takes an historical approach to discuss the process of educati...
journal_title:Chest
pub_type: 历史文章,杂志文章,评审
doi:10.1378/chest.10-0783
更新日期:2011-05-01 00:00:00
abstract::Extrinsic compression of the left main coronary artery (LMCA) can occur in patients with severe pulmonary hypertension and enlarged pulmonary artery trunk. It has been usually described in the setting of congenital defects such as atrial septal defect, ventricular septal defect, and, more rarely, isolated persistent d...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.08-2922
更新日期:2009-06-01 00:00:00
abstract:STUDY OBJECTIVES:Pulmonary rehabilitation (PR) that includes exercise training can improve exercise tolerance and quality of life for patients with COPD. However, the degree of benefit from PR is variable. We hypothesized that the exercise response to PR varies depending on the initial factors that limit exercise. DES...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.127.1.110
更新日期:2005-01-01 00:00:00
abstract::Due to concerns about the efficacy and safety of using pulmonary artery catheterization to evaluate hemodynamic status, noninvasive diagnostic testing has gained increased importance. This article focuses on both the supportive evidence and the limitations of applying the vascular pedicle width (VPW), which is the med...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.121.3.942
更新日期:2002-03-01 00:00:00
abstract:BACKGROUND:The coronavirus disease 2019 (COVID-19) pandemic has severely affected ICUs and critical care health-care providers (HCPs) worldwide. RESEARCH QUESTION:How do regional differences and perceived lack of ICU resources affect critical care resource use and the well-being of HCPs? STUDY DESIGN AND METHODS:Betw...
journal_title:Chest
pub_type: 杂志文章
doi:10.1016/j.chest.2020.09.070
更新日期:2020-09-11 00:00:00
abstract::Pulmonary embolism is a common and potentially lethal disease. Given the variable presentation and associated morbidity of this condition, an accurate and efficient diagnostic algorithm is required. Clinical pretest probability serves as the root of any diagnostic approach. We, thus, review several clinical decision r...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.10-2468
更新日期:2011-08-01 00:00:00
abstract::A total of 161 patients with chronic obstructive pulmonary disease (COPD) plus 100 control subjects (identified during a study of heart disease in 6,860 Japanese-American men aged 52 to 75 years who were residing in Hawaii) were analyzed for phenotype in search of the antitrypsin gene Z, which has been shown to be ass...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.72.4.489
更新日期:1977-10-01 00:00:00
abstract::A new, simpler method to re-expand collapsed lungs was introduced in 14 procedures in 12 critically ill patients. To close the bronchus, we wedge the fiberoptic bronchoscope into each segment or subsegment of the collapsed lung instead of using a balloon cuff. Room air was then insufflated into the atelectatic alveoli...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.97.2.435
更新日期:1990-02-01 00:00:00
abstract:OBJECTIVES:To review statistics on smoking prevalence and to analyze whether the implementation of national tobacco control legislation had an association with the prevalence of smoking, and thereby, with the occurrence of smoking-related lung diseases. DESIGN:Smoking prevalence rates (from 1960 to 2000), lung cancer ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.126.6.1825
更新日期:2004-12-01 00:00:00
abstract::We present a case of azathioprine-associated alveolitis diagnosed by gallium-67 scanning and transbronchial biopsy. The patient denied respiratory symptoms, exhibited spiking fevers, and had normal chest roentgenograms. Allopurinol inhibition of azathioprine metabolism may have been a contributing factor. ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.83.4.696
更新日期:1983-04-01 00:00:00
abstract::This study compared the bronchodilator effect in experimental canine asthma of dyphylline administered by aerosol and intravenous routes in doses producing equivalent concentrations of the drug in the plasma. Pulmonary resistance (RL) was calculated from simultaneous measurements of pressure and flow during fixed-volu...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.79.4.454
更新日期:1981-04-01 00:00:00
abstract:BACKGROUND:Clinical resolution of ventilator-associated pneumonia (VAP) determines the duration of treatment and mechanical ventilation. The aim of this study was to evaluate the influence of organisms and their susceptibility to treatment on outcomes. METHODS:Prospective observational study in three teaching ICUs. Si...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.07-2020
更新日期:2008-03-01 00:00:00
abstract::The adverse effects of prolonged immobility are due primarily to gravitational effects on blood flow and ventilation, impairment of the normal mucociliary escalator and possibly an increase in extravascular lung water. However, CLRT theoretically should reverse these abnormalities. The sequence of events that culminat...
journal_title:Chest
pub_type: 临床试验,杂志文章,随机对照试验,评审
doi:10.1378/chest.99.5.1263
更新日期:1991-05-01 00:00:00
abstract:CASE PRESENTATION:A 38-year-old man of Indian origin, who migrated to Greece 13 years prior to presentation, was admitted to our hospital with a 2-month history of nonprogressive, intermittent (mostly evening), low-grade (up to 38.5°C) fever, accompanied by night sweats, dry cough, mild dyspnea on exertion (modified Me...
journal_title:Chest
pub_type: 杂志文章
doi:10.1016/j.chest.2018.05.012
更新日期:2018-10-01 00:00:00
abstract:BACKGROUND:An arterial stiffness parameter, the cardio-ankle vascular index (CAVI), has been developed. CAVI is adjusted for BP and can be used to measure arterial stiffness with little influence of BP. The purpose of this study was to evaluate the reproducibility, validity, and clinical usefulness of CAVI among patien...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.09-0178
更新日期:2009-09-01 00:00:00
abstract::Considerable heterogeneity persists in the conduct and reporting of statistical analyses in the medical literature. Authors submitting manuscripts to CHEST are encouraged to adhere to the following guidelines where possible. ...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1016/j.chest.2019.10.064
更新日期:2020-07-01 00:00:00
abstract::Activated charcoal usually provides effective and safe treatment for drug overdose. We describe a patient who developed bronchiolitis obliterans and respiratory failure following aspiration of activated charcoal. This patient had a markedly reduced vital capacity with roentgenographic evidence of airtrapping. Chest ro...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.96.3.672
更新日期:1989-09-01 00:00:00
abstract::The influence of positive expiratory pressure (PEP) applied during inhalation of a beta 2-agonist in treatment of bronchial asthma was investigated in a randomized crossover study with two-week treatment periods. In one period, two puffs (0.5 mg) of terbutaline was given from a metered dose inhaler and inhaled through...
journal_title:Chest
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1378/chest.100.2.317
更新日期:1991-08-01 00:00:00
abstract::We describe a patient with hemodynamic deterioration and worsening mitral regurgitation related to right ventricular apex pacing. Time-dependent changes in papillary muscle contraction as well as ventricular remodeling by right ventricular apex pacing might be responsible for this rare but serious complication. ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.114.6.1776
更新日期:1998-12-01 00:00:00
abstract:INTRODUCTION:CT scan-guided fine-needle aspiration (FNA) of lung nodules is a well-established diagnostic technique. In our institution, both FNA and tissue core biopsy (using a 20-gauge needle) under CT scan guidance are routinely performed during the same procedure, and a preliminary diagnosis (an immediate assessmen...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.126.3.739
更新日期:2004-09-01 00:00:00
abstract:BACKGROUND:We aimed to evaluate the availability and practice of spirometry, training of technicians, and spirometer features and maintenance in Spain in both primary care (PC) and secondary care (SC) centers. METHODS:We used a nationwide, cross-sectional, 36-item telephone survey of health-care centers in Spain to ta...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.12-2690
更新日期:2013-08-01 00:00:00
abstract::Peripheral undefined pulmonary nodules have become a favorable indication for the videoendoscopic approach in thoracic surgery. In our latest experience, we also successfully applied this technique in centrally located lesions of the lung. In reviewing our first 29 cases, we looked for preoperative features of videoen...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.106.5.1570
更新日期:1994-11-01 00:00:00
abstract::The history holds the central role in distinguishing among asthma, chronic bronchitis, and emphysema. A personal or family history of atopy, a history of seasonal worsening of disease in response to a known environmental agent, perhaps seasonal, and marked variability in the severity of airflow obstruction, often with...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.87.1.35s
更新日期:1985-01-01 00:00:00
abstract::Exertional dyspnea is a common complaint for patients seen in pulmonary, cardiac, and general medicine clinics, and elucidating the cause is often challenging, particularly when physical examination, echocardiography, radiography, and pulmonary function test results are inconclusive. Invasive cardiopulmonary exercise ...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1016/j.chest.2020.05.552
更新日期:2020-11-01 00:00:00
abstract::Mitral, aortic, and coronary arterial disease have been described in the various mucopolysaccharidoses. We report the first successful combined aortic and mitral valve replacement in an adult female patient with severe aortic and mitral stenosis due to Scheie's syndrome, a mucopolysaccharide storage disease. Both annu...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.96.1.209
更新日期:1989-07-01 00:00:00