Abstract：
STUDY DESIGN:A case report. OBJECTIVES:To demonstrate stimulating action of F XIII in wound healing of complicated pressure sores. SETTING:A Spinal Cord Injury Center in Germany. METHODS:Clinical exam, clinical and photographic wound control, biochemical serum monitoring. RESULTS:Recurrent pressure sores in plegic patients are common complications requiring long-standing conservative or operative therapy. Additional risk factors such as diabetes increase the complication rate for surgery. Surgery itself may be difficult in recurrent pressure sores due to limited remaining soft tissues. We report the case and treatment of a 47-year-old patient with long-standing and recurrent ulcers and complications after flap surgery. As a final option we added plasma transglutaminase (factor XIII) to our treatment scheme which changed the course of the disease dramatically and we achieved complete and rapid healing. CONCLUSION:Our experience suggests that F XIII has a positive role in treating pressure sores as shown already in several other surgical fields. Its use is giving the surgeon an additional tool in complicated cases.
journal_name
Spinal Cordjournal_title
Spinal cordauthors
Becker SW,Weidt F,Röhl Kdoi
10.1038/sj.sc.3101092subject
Has Abstractpub_date
2001-02-01 00:00:00pages
114-7issue
2eissn
1362-4393issn
1476-5624journal_volume
39pub_type
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