Posterior uveal malignant melanoma: temporal stability and ethnic variation in rates in Israel.

abstract：:We retrospectively analysed data from 1751 patients with non-metastatic and non-inflammatory breast cancer treated in our institution between 1977 and 1989, in order to evaluate the link between age and prognosis in breast cancer. We chose three age groups (1): < or = 33 (n = 67), 34-40 ( n = 155), > 40 years (n = 152...

journal_title：Anticancer research

authors： Vanlemmens L,Hebbar M,Peyrat JP,Bonneterre J

更新日期：1998-05-01 00:00:00

abstract：:We have recently reported that phagocytosis of killed Saccharomyces cerevisiae, baker's yeast, induced apoptosis in human breast cancer cell lines MCF-7, ZR-75-1 and HCC70. In this study we have evaluated the effect of treatment with MGN-3, a modified arabinoxylan from rice bran, on phagocytosis and yeast-induced apop...

journal_title：Anticancer research

authors： Ghoneum M,Gollapudi S

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:Taxane-based chemotherapy is useful for peritoneal dissemination control in advanced/recurrent gastric cancer; however, insufficient relative dose intensity (RDI) may preclude disease control achievement. Nab-paclitaxel, with high tumour permeability, is a promising second- or later-line treatment. PATIENTS...

journal_title：Anticancer research

authors： Kanazawa Y,Fujita I,Kakinuma D,Arai H,Matsuno K,Shimoda T,Ko K,Kato S,Uchida E

更新日期：2017-05-01 00:00:00

abstract：AIM:To identify patients with breast cancer at risk for cardiotoxicity, we evaluated homoarginine (HA) behavior during adjuvant treatment. PATIENTS AND METHODS:Eighty-one patients received radiotherapy (RT) with or without endocrine treatment, and 19 received chemotherapy, RT and endocrine therapy. Serum HA, asymmetri...

journal_title：Anticancer research

authors： Aula H,Skyttä T,Tuohinen S,Luukkaala T,Hämäläinen M,Virtanen V,Raatikainen P,Moilanen E,Kellokumpu-Lehtinen PL

更新日期：2017-12-01 00:00:00

abstract：:Transferrin was covalently conjugated to adriamycin (Trf-adr) by the formation of a schiff base. This conjugate was found to bind to cell membrane trf receptors in a variety of human tumor cell lines. The Trf-adr conjugate was found to be active against sensitive and resistant cell lines e.g. Lovo, HL-60, H-meso and H...

journal_title：Anticancer research

authors： Singh M,Atwal H,Micetich R

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND:The effectiveness of postoperative adjuvant chemotherapy for surgically staged grade 3 endometrial cancer was investigated. PATIENTS AND METHODS:Sixty-three consecutive patients with grade 3 endometrial cancer (49 with surgical stage I-II disease and 14 with stage III disease) were treated surgically. Posto...

journal_title：Anticancer research

authors： Takeshima N,Ota T,Omatsu K,Hasumi K,Takizawa K

更新日期：2008-05-01 00:00:00

abstract：:Formalin-fixed paraffin-embedded tumor specimens from 95 patients with supratentorial astrocytic brain tumors were immunostained by a monoclonal antibody against the heat shock protein-27 (Hsp-27) using the streptavidin/peroxidase method. The immunohistochemical analysis was scored in a semiquantitative fashion incorp...

journal_title：Anticancer research

authors： Assimakopoulou M,Sotiropoulou-Bonikou G,Maraziotis T,Varakis I

更新日期：1997-07-01 00:00:00

abstract：:Basal level of asparagine synthetase mRNA in BALB3T3 cells was elevated when the cells were shifted from medium containing a high concentration (3.3 mM) of asparagine to one lacking asparagine. We then studied whether the expression of asparagine synthetase mRNA is also mediated through other asparagine-independent si...

journal_title：Anticancer research

authors： Chiyo T,Hongo S,Takeda M

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND:Gastric cancer is the third most frequent type of neoplasia. In northern Brazil, the State of Pará has a high incidence of this type of neoplasia. Limited data are available so far on the genetic events involved in this disease. MATERIALS AND METHODS:Dual-color fluorescence in situ hybridization (FISH) for ...

journal_title：Anticancer research

authors： Calcagno DQ,Leal MF,Taken SS,Assumpção PP,Demachki S,Smith Mde A,Burbano RR

更新日期：2005-11-01 00:00:00

abstract：:The antitumor effect of endogenous tumor necrosis factor (en-TNF) with cyclophosphamide (CY) was analyzed using the murine Meth A tumor model. En-TNF was induced by the administration of interferon-gamma (4 micrograms/kg: 1 x 10(4) units/ mouse) as a primer and Streptococcus preparation OK-432 (100 KE/kg) as a trigger...

journal_title：Anticancer research

authors： Inagawa H,Ohshiro S,Nishizawa T,Goto S,Soma G,Mizuno D

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND/AIM:It is well-known that inflammatory bowel disease (IBD) poses an increased, yet not definitely estimated, risk of colitis-associated colon cancer (CAC), which is considered a more aggressive and distinct in both genetic and molecular levels clinical entity compared to sporadic colorectal cancer (CRC). The...

journal_title：Anticancer research

authors： Antoniou E,Margonis GA,Angelou A,Zografos GC,Pikoulis E

更新日期：2015-01-01 00:00:00

abstract：:The relationship between production of Colony-Stimulating Factor (CSF) and metastasis has been investigated in the TS/A murine model. CSF production was determined in TS/A cell variants isolated through serial in vivo selection of lung metastatic nodules induced by intravenous or subcutaneous injection of tumor cells ...

journal_title：Anticancer research

authors： Nicoletti G,Lollini PL,Bagnara GP,De Giovanni C,Del Re B,Bons L,Prodi G,Nanni P

更新日期：1987-07-01 00:00:00

abstract：:Considerable progress has recently been achieved in understanding the pathogenesis of human immunodeficiency virus type 1 (HIV-1), and in improving the efficacy of antiretroviral therapies for the treatment of patients with the acquired immunodeficiency syndrome (AIDS). The pharmacological properties of new drugs are ...

journal_title：Anticancer research

authors： Romano G,Massi D,Giordano A

更新日期：1998-07-01 00:00:00

abstract：AIM:To evaluate the influence on relapse-free survival (RFS) and overall survival (OS) of a transitory protective stoma (TPS) at the time of complete cytoreductive surgery for advanced-stage ovarian cancer. PATIENTS AND METHODS:From our Institution, we retrospectively selected patients from 2006 to 2011 with ovarian c...

journal_title：Anticancer research

authors： Canlorbe G,Touboul C,Chargari C,Bentivegna E,Maulard A,Pautier P,Genestie C,Morice P,Gouy S

更新日期：2018-03-01 00:00:00

abstract：AIM:To evaluate the role of low mechanical index (MI) contrast-enhanced sonography (CEUS) for the characterization of small hepatocellular carcinomas (HCC) in cirrhotic patients by comparing the results to ultrafast dynamic gadolinium-enhanced magnetic resonance imaging (MRI) studies. MATERIALS AND METHODS:Between Sep...

journal_title：Anticancer research

authors： Giorgio A,De Stefano G,Coppola C,Ferraioli G,Esposito V,Di Sarno A,Giorgio V,De Stefano M,Sangiovanni V,Liorre G,Del Viscovo L

更新日期：2007-11-01 00:00:00

abstract：:2-4 Dinitrochlorobenzene (D.N.C.B.) is a synthetic primary allergenic molecule which has proved to have at least two useful clinical applications as regards neoplastic conditions. As a diagnostic measure, it serves in the detection of global alterations of cellular immunity. As a therapeutical measure, its epicutaneou...

journal_title：Anticancer research

authors： Truchetet F,Heid E,Friedel J,Chartier C,Grosshans E

更新日期：1989-11-01 00:00:00

abstract：BACKGROUND/AIM:Lung cancer is the first cause of cancer related deaths in both males and females. Epithelial-mesenchymal transition (EMT) is a reversible process by which epithelial cells transform to mesenchymal stem cells by losing their cell polarity and cell-to-cell adhesion, gaining migratory and invasive properti...

journal_title：Anticancer research

authors： Tsoukalas N,Aravantinou-Fatorou E,Tolia M,Giaginis C,Galanopoulos M,Kiakou M,Kostakis ID,Dana E,Vamvakaris I,Korogiannos A,Tsiambas E,Salemis N,Kyrgias G,Karameris A,Theocharis S

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Prediction of biological behavior is crucial for selection of new therapeutic modalities in GIST. Here, we aimed to assess whether KIT and PDGFRA mutations have survival impact in gastrointestinal stromal tumors (GIST). PATIENTS AND METHODS:Fifty-five Brazilian patients with completely resected GIST were ex...

journal_title：Anticancer research

authors： Braggio E,Braggio Dde A,Small IA,Lopes LF,Valadão M,Gouveia ME,Moreira Ados S,Linhares E,Romano S,Bacchi CE,Renault IZ,Guimarães DP,Ferreira CG

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Hyaluronan is one of the main components of the extracellular matrix. It is synthesized at the cell plasma membrane by specific hyaluronan synthases (HAS). Although a large number of studies have described hyaluronan in pleural effusion from malignant mesothelioma, the source of hyaluronan in malignant mesot...

journal_title：Anticancer research

authors： Liu Z,Dobra K,Hauzenberger D,Klominek J

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:Circulating nucleosomes are valuable biomarkers for therapy monitoring and estimation of prognosis in cancer disease. While epigenetic and genetic modifications of DNA have been reported in blood of cancer patients, little is known about modifications of histones on circulating nucleosomes. PATIENTS AND MET...

journal_title：Anticancer research

authors： Leszinski G,Gezer U,Siegele B,Stoetzer O,Holdenrieder S

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND/AIM:Inflammation is a key process in gastric carcinogenesis. Cytokines are mediators of inflammation and are involved in metastasis and tumorigenicity. We previously assessed the role of cytokine gene polymorphisms in gastric cancer risk in Chile. In the present study, we aimed to analyze whether these polym...

journal_title：Anticancer research

authors： Gonzalez-Hormazabal P,Romero S,Musleh M,Bustamante M,Stambuk J,Pisano R,Lanzarini E,Chiong H,Rojas J,Castro VG,Jara L,Berger Z

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:A number of association studies have focused on the effect of polymorphisms related to DNA repair or the xenobiotic pathway, on the susceptibility to gastric cancer (GC). Here, the possible association between common polymorphisms in the X-ray repair cross-complementing groups (XRCC) 1, and glutathione-S-tra...

journal_title：Anticancer research

authors： Tahara T,Shibata T,Nakamura M,Yamashita H,Yoshioka D,Okubo M,Yonemura J,Ishizuka T,Maruyama N,Kamano T,Kamiya Y,Fujita H,Nakagawa Y,Nagasaka M,Iwata M,Yamada H,Hirata I,Arisawa T

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Clofarabine is a second-generation nucleoside analogue. The aim of the study was the analysis of ex vivo activity of clofarabine and 14 other anticancer drugs in pediatric and adult acute lymphoblastic (ALL) and myeloid (AML) leukemia. PATIENTS AND METHODS:The ex vivo drug resistance profile was analyzed in...

journal_title：Anticancer research

authors： Styczynski J,Gil L,Derwich K,Wachowiak J,Balwierz W,Badowska W,Krawczuk-Rybak M,Matysiak M,Wieczorek M,Balcerska A,Sonta-Jakimczyk D,Stefaniak J,Kowalczyk J,Urasinski T,Sobol G,Komarnicki M,Wysocki M

更新日期：2009-05-01 00:00:00

abstract：:A copper complex with superoxide dismutase mimetic activity, Cu(II)2 (3,5-diisopropylsalicylate)4 (CuDIPS), was tested for activity against mammary cancer in female C3H/HeNCR mice. Initiation of treatment at 20 or at 30 weeks of age had a limited beneficial effect on survival rates. Further, a small, but not statistic...

journal_title：Anticancer research

authors： Crispens CG Jr,Sorenson JR

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:In the present study, 3 cytotoxic agents were combined as front-line chemotherapy in advanced non-small cell lung cancer (NSCLC) patients. All 3 drugs have been used in other 2-agent combinations and have been shown to be effective as first-line therapy. PATIENTS AND METHODS:Sixty-one (53 male, 8 female, me...

journal_title：Anticancer research

authors： Dimitroulis J,Toubis M,Antoniou D,Marosis C,Armenaki U,Stathopoulos GP,Giamboudakis P,Veslemes M,Michalopoulou P,Christou F,Georgatou N,Grigoratou T,Karaindros D,Katis K,SOLCA Study Group.

更新日期：2006-03-01 00:00:00

abstract：:Binding of 20-[3H]-phorbol 2, 13-dibutyrate [( 3H] PDB) to intact human K 562 cells was characterized. Specific binding of [3H] PDB to K 562 cells at 20 degrees C or 37 degrees C reached a maximum within 15-20 min. Maximal specific [3H] PDB binding to K 562 cells was followed by a decline (down regulation) of radioact...

journal_title：Anticancer research

authors： Louache F,Villeval JL,Pelicci PG,Rouis M,Titeux M,Henri A,Rochant H,Thomopoulos P,Testa U

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND/AIM:Gefitinib and erlotinib were shown to be particularly effective in a clinically selected subpopulation of non-small cell lung cancer patients (NSCLC): adenocarcinoma histology, non-smoking status, Asian origin and female gender have been associated with improved clinical benefit compared to the unselecte...

journal_title：Anticancer research

authors： Bonanno L,Schiavon M,Nardo G,Bertorelle R,Bonaldi L,Galligioni A,Indraccolo S,Pasello G,Rea F,Favaretto A

更新日期：2010-12-01 00:00:00

abstract：AIM:We aimed to retrospectively investigate the outcomes and pathological effects of retrograde superselective intra-arterial chemoradiotherapy (IACRT) combined with hyperthermia on metastatic lymph nodes of patients with oral squamous cell carcinoma. PATIENTS AND METHODS:Patients with lymph node metastasis from oral ...

journal_title：Anticancer research

authors： Nozato T,Koizumi T,Hayashi Y,Iida M,Iwai T,Oguri S,Hirota M,Kioi M,Koike I,Hata M,Tohnai I,Mitsudo K

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Chkl is a checkpoint gene that is activated after DNA damage. It phosphorylates and inactivates Cdc25C at the late G2 phase. The inactivation of Cdc25C and consequently, the inactivation of Cdc2, are required for the G2 arrest induced by DNA damage. METHODS:We treated 184B5 cell line and its E6 transformed ...

journal_title：Anticancer research

authors： Luo Y,Rockow-Magnone SK,Joseph MK,Bradner J,Butler CC,Tahir SK,Han EK,Ng SC,Severin JM,Gubbins EJ,Reilly RM,Rueter A,Simmer RL,Holzman TF,Giranda VL

更新日期：2001-01-01 00:00:00

abstract：:The antitumor effects of the somatostatin structural derivative TT-232 in different rodent and xenograft tumor models are summarized in this report. TT-232 had previously been shown to inhibit the proliferation of a large number of cancer cell lines in vitro and reduce the size of different tumors in animal models in ...

journal_title：Anticancer research

authors： Tejeda M,Gaál D,Hullán L,Hegymegi-Barakonyi B,Kéri G

更新日期：2006-09-01 00:00:00