Abstract:
BACKGROUND:The amplitude of the auditory P3 event-related potential is reduced in patients with axes I and II disorders. Data regarding P3 amplitude and normal personality traits in healthy individuals have been inconsistent, however, although more extreme variants of dimensional traits such as neuroticism and extraversion are associated with psychiatric morbidity. METHODS:Male subjects (n = 18) recruited from the community completed the NEO Five-Factor Inventory, which consists of five scales: Neuroticism, Extraversion, Openness, Agreeableness, and Conscientiousness. P3 potentials were generated using an auditory discrimination paradigm to which a third, novel stimulus was added. Partial least squares analysis, a multivariate statistical procedure, was used to test the relationship, in both stimulus conditions, between P3 amplitude at six electrode sites and the five personality dimensions. RESULTS:P3 amplitude across conditions and sites was positively related to Extraversion, Openness, Agreeableness, and Conscientiousness and negatively related to Neuroticism. CONCLUSIONS:Previous studies have shown that both reduced P3 amplitude and a high Neuroticism/low Extraversion-Openness-Agreeableness-Conscientiousness trait pattern are associated with the presence of, and risk for, substantial psychiatric morbidity. Our results suggest that processes indexed by auditory P3 amplitude are related to these broad personality dimensions in healthy individuals.
journal_name
Biol Psychiatryjournal_title
Biological psychiatryauthors
Gurrera RJ,O'Donnell BF,Nestor PG,Gainski J,McCarley RWdoi
10.1016/s0006-3223(00)01067-2subject
Has Abstractpub_date
2001-06-01 00:00:00pages
922-9issue
11eissn
0006-3223issn
1873-2402pii
S0006322300010672journal_volume
49pub_type
杂志文章abstract::The aim of the present study was to evaluate the pattern of basal cortisol release in PTSD and major depression using a chronobiological analysis. Plasma for cortisol determination was obtained from 15 combat veterans with PTSD, 14 subjects with major depression, and 15 normal men every 30 min during a 24-hour period ...
journal_title:Biological psychiatry
pub_type: 杂志文章
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journal_title:Biological psychiatry
pub_type: 临床试验,杂志文章
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journal_title:Biological psychiatry
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pub_type: 临床试验,杂志文章
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pub_type: 杂志文章,meta分析
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pub_type: 临床试验,杂志文章
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pub_type: 杂志文章,评审
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pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1998-09-01 00:00:00
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journal_title:Biological psychiatry
pub_type: 杂志文章,meta分析
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更新日期:2007-04-01 00:00:00
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journal_title:Biological psychiatry
pub_type: 杂志文章
doi:10.1016/j.biopsych.2004.01.024
更新日期:2004-05-15 00:00:00
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pub_type: 杂志文章
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pub_type: 临床试验,杂志文章
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更新日期:1998-11-15 00:00:00
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journal_title:Biological psychiatry
pub_type: 临床试验,杂志文章
doi:10.1016/j.biopsych.2005.04.022
更新日期:2005-09-15 00:00:00
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pub_type: 杂志文章
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