Abstract:
:In eukaryotic cells, the membranes of different intracellular organelles have different lipid composition, and various biomembranes show an asymmetric distribution of lipid types across the membrane bilayer. Membrane lipid organization reflects a dynamic equilibrium of lipids moving across the bilayer in both directions. In this review, we summarize data supporting the role of specific membrane proteins in catalyzing transbilayer lipid movement, thereby controlling and regulating the distribution of lipids over the leaflets of biomembranes.
journal_name
Semin Cell Dev Bioljournal_title
Seminars in cell & developmental biologyauthors
Pomorski T,Hrafnsdóttir S,Devaux PF,van Meer Gdoi
10.1006/scdb.2000.0231subject
Has Abstractpub_date
2001-04-01 00:00:00pages
139-48issue
2eissn
1084-9521issn
1096-3634pii
S1084-9521(00)90231-3journal_volume
12pub_type
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