Relationships between depression and psychotic symptoms of schizophrenia during an acute episode and stable period.

Abstract:

:The aim of the present study is to explore the relationship between depression and psychotic symptoms of schizophrenia over the course of illness. Sixty-eight patients meeting DSM-IV criteria for schizophrenia were enrolled, 27 in an acute episode, 41 when stable. Assessments were performed using the Calgary Depression Scale for Schizophrenia (CDSS) for depression and the Positive and Negative Syndrome Scale (PANSS) for psychotic symptoms. When considering patients in an acute episode (52% depressed), the CDSS score was correlated only with the PANSS positive sub-scale score. For patients in the stable period (38% depressed), the CDSS score was correlated with positive as well as negative and general psychopathology sub-scale scores. Hence, the relationship between depression and other symptoms of schizophrenia appear to differ during different stages of illness.

journal_name

Schizophr Res

journal_title

Schizophrenia research

authors

Lançon C,Auquier P,Reine G,Bernard D,Addington D

doi

10.1016/s0920-9964(00)00002-5

subject

Has Abstract

pub_date

2001-03-01 00:00:00

pages

135-40

issue

2-3

eissn

0920-9964

issn

1573-2509

pii

S0920996400000025

journal_volume

47

pub_type

杂志文章
  • Psychotic disorder symptom rating scales: Are dichotomous or multi-point scales more clinically useful?-An ICD-11 field study.

    abstract::Classifications of psychotic disorders are moving towards utilizing dimensional symptom domains as the preferred mechanism for describing psychotic symptomatology. The ICD-11 has proposed six symptom domains (Positive symptoms, Negative symptoms, Depressive symptoms, Manic symptoms, Psychomotor symptoms, and Cognitive...

    journal_title:Schizophrenia research

    pub_type: 杂志文章

    doi:10.1016/j.schres.2018.07.006

    authors: Keeley JW,Gaebel W,First MB,Peterson DL,Rebello T,Sharan P,Reed GM

    更新日期:2018-12-01 00:00:00

  • Antipsychotic treatment patterns and hospitalizations among adults with schizophrenia.

    abstract:OBJECTIVE(S):To characterize the longitudinal patterns of antipsychotic treatment and to investigate the relationship between antipsychotic treatment patterns and acute hospitalizations among adults with schizophrenia. We hypothesized that continuous antipsychotic treatment would be associated with fewer hospitalizatio...

    journal_title:Schizophrenia research

    pub_type: 杂志文章

    doi:10.1016/j.schres.2007.12.475

    authors: dosReis S,Johnson E,Steinwachs D,Rohde C,Skinner EA,Fahey M,Lehman AF

    更新日期:2008-04-01 00:00:00

  • Adolescent developmental change in topography of EEG amplitude.

    abstract::EEGs were recorded from 32 channels in 30 normal males, ages 16-22. Delta activity decreased throughout this age range. This decrease was greatest in the left frontal and temporal regions; no occipital lead showed this pattern. Relative EEG amplitude analysis, based on normalized maps, revealed decreases with age acro...

    journal_title:Schizophrenia research

    pub_type: 杂志文章

    doi:10.1016/0920-9964(92)90039-8

    authors: Buchsbaum MS,Mansour CS,Teng DG,Zia AD,Siegel BV Jr,Rice DM

    更新日期:1992-07-01 00:00:00

  • Examining hippocampal function in schizophrenia using a virtual reality spatial navigation task.

    abstract:BACKGROUND:Structural pathology in the hippocampus is well-documented in schizophrenia, but brain functional changes have not been consistently found. We used spatial navigation in a virtual reality environment, a task that is known to produce robust hippocampal activation in healthy subjects, to examine task-related a...

    journal_title:Schizophrenia research

    pub_type: 杂志文章

    doi:10.1016/j.schres.2016.02.033

    authors: Salgado-Pineda P,Landin-Romero R,Portillo F,Bosque C,Pomes A,Spanlang B,Franquelo JC,Teixido C,Sarró S,Salvador R,Slater M,Pomarol-Clotet E,McKenna PJ

    更新日期:2016-04-01 00:00:00

  • Relative indices of treatment effect may be constant across different definitions of response in schizophrenia trials.

    abstract:BACKGROUND:In randomized controlled trials of antipsychotics, various cutoffs have been used to define response on continuous outcome measures. AIMS:To find a summary effect measure that remains constant across different definitions of response. METHOD:We conducted secondary analyses of individual patient data from 1...

    journal_title:Schizophrenia research

    pub_type: 杂志文章,meta分析

    doi:10.1016/j.schres.2010.10.016

    authors: Furukawa TA,Akechi T,Wagenpfeil S,Leucht S

    更新日期:2011-03-01 00:00:00

  • An assessment of the Wisconsin Card Sorting Test as an indicator of liability to schizophrenia.

    abstract::In order to test the hypothesis that a poor performance in the Wisconsin test (WCST) may be an indicator of liability to schizophrenia, we compared the WCST performances of patients with DSM III-R schizophrenia, normal controls, and patients with schizotypal personality disorder (SZT PD). While schizophrenic patients ...

    journal_title:Schizophrenia research

    pub_type: 杂志文章

    doi:10.1016/0920-9964(94)90007-8

    authors: Battaglia M,Abbruzzese M,Ferri S,Scarone S,Bellodi L,Smeraldi E

    更新日期:1994-12-01 00:00:00

  • Reduced auditory P300 amplitude, medial temporal volume reduction and psychopathology in schizophrenia.

    abstract::Twenty-five schizophrenic patients diagnosed by DSM-III-R underwent event-related potentials and magnetic resonance imaging scans. Latency and amplitude of P300 waveform were measured using an auditory odd-ball paradigm. Anterior and posterior volumes of the superior temporal gyrus and medial temporal structure were m...

    journal_title:Schizophrenia research

    pub_type: 杂志文章

    doi:10.1016/s0920-9964(97)00055-8

    authors: Kawasaki Y,Maeda Y,Higashima M,Nagasawa T,Koshino Y,Suzuki M,Ide Y

    更新日期:1997-08-29 00:00:00

  • Psychotic experiences in childhood are associated with increased structural integrity of the left arcuate fasciculus - A population-based case-control study.

    abstract::Around 1 in 5 children under 13 years old experience sub-clinical psychotic experiences (PEs) like hallucinations and delusions. While PEs in childhood are a significant risk factor for adult psychotic disorders, the majority of those experiencing childhood PEs do not develop a psychotic disorder. Individual differenc...

    journal_title:Schizophrenia research

    pub_type: 杂志文章

    doi:10.1016/j.schres.2019.08.022

    authors: Dooley N,O'Hanlon E,Healy C,Adair A,McCandless C,Coppinger D,Kelleher I,Clarke M,Leemans A,Frodl T,Cannon M

    更新日期:2020-01-01 00:00:00

  • Impact of physical activity on functioning of patients with first-episode psychosis--a 6 months prospective longitudinal study.

    abstract::There has been increasing interest in studying the impact of physical activity on the psychological and physical well-being and functioning in patients with first-episode psychosis. The exploration of factors which contribute to physical activity in psychosis may open up opportunities for improvement of functional out...

    journal_title:Schizophrenia research

    pub_type: 杂志文章

    doi:10.1016/j.schres.2013.08.034

    authors: Lee EH,Hui CL,Chang WC,Chan SK,Li YK,Lee JT,Lin JJ,Chen EY

    更新日期:2013-11-01 00:00:00

  • MATRICS cognitive consensus battery (MCCB) performance in children, adolescents, and young adults.

    abstract:BACKGROUND:Neurodevelopmental models of schizophrenia suggest that cognitive deficits may be observed during childhood and adolescence, long before the onset of psychotic symptoms. Elucidating the trajectory of normal cognitive development during childhood and adolescence may therefore provide a basis for identifying s...

    journal_title:Schizophrenia research

    pub_type: 杂志文章

    doi:10.1016/j.schres.2013.11.023

    authors: Nitzburg GC,Derosse P,Burdick KE,Peters BD,Gopin CB,Malhotra AK

    更新日期:2014-01-01 00:00:00

  • Area deprivation, urbanicity, severe mental illness and social drift - A population-based linkage study using routinely collected primary and secondary care data.

    abstract::We investigated whether associations between area deprivation, urbanicity and elevated risk of severe mental illnesses (SMIs, including schizophrenia and bipolar disorder) is accounted for by social drift or social causation. We extracted primary and secondary care electronic health records from 2004 to 2015 from a po...

    journal_title:Schizophrenia research

    pub_type: 杂志文章

    doi:10.1016/j.schres.2020.03.044

    authors: Lee SC,DelPozo-Banos M,Lloyd K,Jones I,Walters JTR,Owen MJ,O'Donovan M,John A

    更新日期:2020-06-01 00:00:00

  • Longitudinal course of self-labeling, stigma stress and well-being among young people at risk of psychosis.

    abstract::Stigma may undermine the well-being of young people at risk of psychosis. We therefore measured self-labeling, stigma variables and well-being at baseline and again one year later among 77 at-risk participants. An increase in self-labeling during this period predicted heightened stigma stress after one year and a decr...

    journal_title:Schizophrenia research

    pub_type: 杂志文章

    doi:10.1016/j.schres.2014.07.016

    authors: Rüsch N,Müller M,Heekeren K,Theodoridou A,Metzler S,Dvorsky D,Corrigan PW,Walitza S,Rössler W

    更新日期:2014-09-01 00:00:00

  • A preliminary study of interactive questioning methods to assess and improve understanding of informed consent among patients with schizophrenia.

    abstract::Growing recognition of the inadequacy of traditional methods of providing informed consent, especially for individuals vulnerable to impaired decisional capacity, has spurred recent interest in how to assess and improve components of consent-related decision making. In this preliminary study, we aimed to compare diffe...

    journal_title:Schizophrenia research

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.schres.2004.06.009

    authors: Eyler LT,Mirzakhanian H,Jeste DV

    更新日期:2005-06-15 00:00:00

  • Adverse pregnancy outcome in schizophrenic women: occurrence and risk factors.

    abstract::Low birth weight and preterm birth are important predictors of infant mortality and morbidity, and may increase the risk of schizophrenia. These adverse outcomes of pregnancy could be associated, therefore, with increased risk in children genetically predisposed to schizophrenia. The aim of this review was to describe...

    journal_title:Schizophrenia research

    pub_type: 杂志文章,评审

    doi:10.1016/s0920-9964(98)00065-6

    authors: Bennedsen BE

    更新日期:1998-09-07 00:00:00

  • Evidence for schizophrenia susceptibility alleles in the Indian population: An association of neurodevelopmental genes in case-control and familial samples.

    abstract::Schizophrenia is a severe psychiatric disorder with lifetime prevalence of ~1% worldwide. A genotyping study was conducted using a custom panel of Illumina 1536 SNPs in 840 schizophrenia cases and 876 controls (351 patients and 385 controls from North India; and 436 patients, 401 controls and 143 familial samples with...

    journal_title:Schizophrenia research

    pub_type: 杂志文章,meta分析

    doi:10.1016/j.schres.2014.12.031

    authors: Jajodia A,Kaur H,Kumari K,Gupta M,Baghel R,Srivastava A,Sood M,Chadda RK,Jain S,Kukreti R

    更新日期:2015-03-01 00:00:00

  • Motor abnormalities and cognitive impairment in first-episode psychosis patients, their unaffected siblings and healthy controls.

    abstract::Motor abnormalities (MAs) may be already evidenced long before the beginning of illness and are highly prevalent in psychosis. However, the extent to which the whole range of MAs are related to cognitive impairment in psychosis remains understudied. This study aimed to examine comparatively the relationships between t...

    journal_title:Schizophrenia research

    pub_type: 杂志文章

    doi:10.1016/j.schres.2017.10.035

    authors: Cuesta MJ,Moreno-Izco L,Ribeiro M,López-Ilundain JM,Lecumberri P,Cabada T,Lorente-Omeñaca R,Sánchez-Torres AM,Gómez MS,Peralta V

    更新日期:2018-10-01 00:00:00

  • Further evidence for an association between schizophrenia and the HLA DQB1 gene locus.

    abstract::A case-control study was conducted in Singapore, in order to examine a proposed association between schizophrenia and the HLA DQB1 gene locus. The probands were male inpatients of Chinese ethnicity with schizophrenia (ICD-10 criteria, n = 102) and the controls were adults matched for gender and ethnicity (n = 111). Po...

    journal_title:Schizophrenia research

    pub_type: 杂志文章

    doi:10.1016/0920-9964(95)00023-2

    authors: Nimgaonkar VL,Rudert WA,Zhang XR,Tsoi WF,Trucco M,Saha N

    更新日期:1995-12-01 00:00:00

  • Differences in distribution of ages of onset in males and females with schizophrenia.

    abstract::An earlier age at onset of schizophrenia in men as opposed to women, has been widely reported, but hitherto, insufficient account has been taken of parameters that might confound this finding. Furthermore, few explanatory models have accounted for the differences in shape of the age-at-onset distributions in males and...

    journal_title:Schizophrenia research

    pub_type: 杂志文章

    doi:10.1016/s0920-9964(98)00070-x

    authors: Castle D,Sham P,Murray R

    更新日期:1998-10-09 00:00:00

  • Pronounced prefronto-temporal cortical thinning in schizophrenia: Neuroanatomical correlate of suicidal behavior?

    abstract::Schizophrenia is characterized by increased mortality for which suicidality is the decisive factor. An analysis of cortical thickness and folding to further elucidate neuroanatomical correlates of suicidality in schizophrenia has not yet been performed. We searched for relevant brain regions with such differences betw...

    journal_title:Schizophrenia research

    pub_type: 杂志文章

    doi:10.1016/j.schres.2016.08.010

    authors: Besteher B,Wagner G,Koch K,Schachtzabel C,Reichenbach JR,Schlösser R,Sauer H,Schultz CC

    更新日期:2016-10-01 00:00:00

  • Neurocognitive and linguistic correlates of positive and negative formal thought disorder: A meta-analysis.

    abstract::Executive dysfunction and language impairment are the most prominent neuropsychological models of formal thought disorder (FTD) in schizophrenia. However, available studies have provided contradictory findings regarding the accuracy of these models. Furthermore, specific neurocognitive underpinnings of positive FTD (P...

    journal_title:Schizophrenia research

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.schres.2019.05.025

    authors: Bora E,Yalincetin B,Akdede BB,Alptekin K

    更新日期:2019-07-01 00:00:00

  • Decreased synaptic and mitochondrial density in the postmortem anterior cingulate cortex in schizophrenia.

    abstract::Schizophrenia (SZ) is a mental illness characterized by psychosis, negative symptoms, and cognitive deficits. The anterior cingulate cortex (ACC), a structurally and functionally diverse region, is one of several brain regions that is abnormal in SZ. The present study compared synaptic organization and mitochondrial n...

    journal_title:Schizophrenia research

    pub_type: 杂志文章

    doi:10.1016/j.schres.2015.07.016

    authors: Roberts RC,Barksdale KA,Roche JK,Lahti AC

    更新日期:2015-10-01 00:00:00

  • Ventral and dorsal visual pathways exhibit abnormalities of static and dynamic connectivities, respectively, in patients with schizophrenia.

    abstract::Previous studies suggest that schizophrenia-related visual perceptual abnormalities are primarily attributed to deficits of the dorsal rather than ventral visual pathway. In this study, we comparatively explored changes in dorsal and ventral networks in schizophrenia patients in both static and dynamic functional conn...

    journal_title:Schizophrenia research

    pub_type: 杂志文章

    doi:10.1016/j.schres.2018.12.005

    authors: Deng Y,Liu K,Cheng D,Zhang J,Chen H,Chen B,Li Y,Wang W,Kong Y,Wen G

    更新日期:2019-04-01 00:00:00

  • Validation of mismatch negativity and P3a for use in multi-site studies of schizophrenia: characterization of demographic, clinical, cognitive, and functional correlates in COGS-2.

    abstract::Mismatch negativity (MMN) and P3a are auditory event-related potential (ERP) components that show robust deficits in schizophrenia (SZ) patients and exhibit qualities of endophenotypes, including substantial heritability, test-retest reliability, and trait-like stability. These measures also fulfill criteria for use a...

    journal_title:Schizophrenia research

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.schres.2014.09.042

    authors: Light GA,Swerdlow NR,Thomas ML,Calkins ME,Green MF,Greenwood TA,Gur RE,Gur RC,Lazzeroni LC,Nuechterlein KH,Pela M,Radant AD,Seidman LJ,Sharp RF,Siever LJ,Silverman JM,Sprock J,Stone WS,Sugar CA,Tsuang DW,Tsuang MT

    更新日期:2015-04-01 00:00:00

  • Structural correlates of formal thought disorder in schizophrenia: An ultra-high field multivariate morphometry study.

    abstract:BACKGROUND:Persistent formal thought disorder (FTD) is one of the most characteristic features of schizophrenia. Several neuroimaging studies report spatially distinct neuroanatomical changes in association with FTD. Given that most studies so far have employed a univariate localisation approach that obscures the study...

    journal_title:Schizophrenia research

    pub_type: 杂志文章

    doi:10.1016/j.schres.2015.07.022

    authors: Palaniyappan L,Mahmood J,Balain V,Mougin O,Gowland PA,Liddle PF

    更新日期:2015-10-01 00:00:00

  • Reduced fractional anisotropy and axial diffusivity in white matter in 22q11.2 deletion syndrome: a pilot study.

    abstract::Individuals with 22q11.2 deletion syndrome (22q11.2DS) evince a 30% incidence of schizophrenia. We compared the white matter (WM) of 22q11.2DS patients without schizophrenia to a group of matched healthy controls using Tract-Based-Spatial-Statistics (TBSS). We found localized reduction of Fractional Anisotropy (FA) an...

    journal_title:Schizophrenia research

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.schres.2012.06.032

    authors: Kikinis Z,Asami T,Bouix S,Finn CT,Ballinger T,Tworog-Dube E,Kucherlapati R,Kikinis R,Shenton ME,Kubicki M

    更新日期:2012-10-01 00:00:00

  • Repetitive transcranial magnetic stimulation for negative symptoms of schizophrenia: a randomized controlled pilot study.

    abstract:BACKGROUND:Negative symptoms in schizophrenia are associated with deficits in executive function and frequently prove highly resistant to neuroleptic medication. Using repetitive transcranial magnetic stimulation (rTMS) to activate the prefrontal cortex has been suggested as a treatment for negative symptoms. METHODS:...

    journal_title:Schizophrenia research

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.schres.2007.03.016

    authors: Mogg A,Purvis R,Eranti S,Contell F,Taylor JP,Nicholson T,Brown RG,McLoughlin DM

    更新日期:2007-07-01 00:00:00

  • Two complex genotypes relevant to the kynurenine pathway and melanotropin function show association with schizophrenia and bipolar disorder.

    abstract::Prior studies of mRNA expression, protein expression, and pathway metabolite levels have implicated dysregulation of the kynurenine pathway in the etiology of schizophrenia and bipolar disorder. Here we investigate whether genes involved in kynurenine pathway regulation might interact with genes that respond to kynure...

    journal_title:Schizophrenia research

    pub_type: 杂志文章

    doi:10.1016/j.schres.2009.05.014

    authors: Miller CL,Murakami P,Ruczinski I,Ross RG,Sinkus M,Sullivan B,Leonard S

    更新日期:2009-09-01 00:00:00

  • Trends in psychiatric hospitalisation of people with schizophrenia: a register-based investigation over the last three decades.

    abstract::The number of psychiatric beds has declined considerably in many countries over the past decades. Long-term studies on the impact of these health care changes for the severely mentally ill, however, are still scarce. This epidemiological study investigates the use of inpatient psychiatric services by people with schiz...

    journal_title:Schizophrenia research

    pub_type: 杂志文章

    doi:10.1016/j.schres.2007.07.006

    authors: Lay B,Nordt C,Rössler W

    更新日期:2007-12-01 00:00:00

  • Autoimmune diseases, gastrointestinal disorders and the microbiome in schizophrenia: more than a gut feeling.

    abstract::Autoimmunity, gastrointestinal (GI) disorders and schizophrenia have been associated with one another for a long time. This paper reviews these connections and provides a context by which multiple risk factors for schizophrenia may be related. Epidemiological studies strongly link schizophrenia with autoimmune disorde...

    journal_title:Schizophrenia research

    pub_type: 杂志文章,评审

    doi:10.1016/j.schres.2014.06.027

    authors: Severance EG,Yolken RH,Eaton WW

    更新日期:2016-09-01 00:00:00

  • Behavioral effects of non-viral mediated RNA interference of synapsin II in the medial prefrontal cortex of the rat.

    abstract::Synapsin II is a synaptic vesicle-associated phosphoprotein that has been implicated in the pathophysiology of schizophrenia. Researchers have demonstrated reductions in synapsin II mRNA and protein in post-mortem prefrontal cortex and hippocampus samples from patients with schizophrenia. Synapsin II protein expressio...

    journal_title:Schizophrenia research

    pub_type: 杂志文章

    doi:10.1016/j.schres.2012.01.029

    authors: Dyck BA,Tan ML,Daya RP,Basu D,Sookram CD,Thomas N,Mishra RK

    更新日期:2012-05-01 00:00:00