Lipid chemotaxis and signal transduction in Myxococcus xanthus.

Abstract:

:The lipid phosphatidylethanolamine (PE) is the first chemoattractant to be described for a surface-motile bacterium. In Myxococcus xanthus, the specific activity of PE is determined by its fatty acid components. Two active species have been identified: dilauroyl PE and dioleoyl PE. Excitation to dilauroyl PE requires fibril appendages and the presence of two cytoplasmic chemotaxis systems, of which one (Dif) appears to mediate excitation and the other (Frz) appears to mediate adaptation. A possible mechanism for fibril-mediated signal transduction is discussed, along with the potential roles for PE chemotaxis in the context of the M. xanthus life cycle.

journal_name

Trends Microbiol

journal_title

Trends in microbiology

authors

Kearns DB,Shimkets LJ

doi

10.1016/s0966-842x(01)01948-5

subject

Has Abstract

pub_date

2001-03-01 00:00:00

pages

126-9

issue

3

eissn

0966-842X

issn

1878-4380

pii

S0966-842X(01)01948-5

journal_volume

9

pub_type

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