Prevention of secondary osteoporosis postmenopause in hemiplegia.

Abstract:

OBJECTIVES:To study secondary osteoporosis postmenopause in women with hemiplegia and to show the therapeutic effects of etidronate and how osteoporotic conditions relate to the activities of daily living (ADL). DESIGN:Eighty-one postmenopausal women with hemiplegia were admitted within 6 mo of their first cerebrovascular accident. The bone mineral density (BMD) and biochemical markers of bone turnover were measured at the time of admission. Forty women (treatment group) received a 2-wk administration of etidronate. Forty-one women (control group) were not administered etidronate. RESULTS:After completing a 3-mo rehabilitation program, BMD levels were remeasured. ADL was evaluated by FIM. The low ADL group had a larger decrease in BMD than the high ADL group. For the control group, the BMD rate of change on the paretic side of the femoral neck was -9.6%/3 mo for the low ADL group. BMD loss was reduced significantly by the administration of etidronate for the low ADL group. CONCLUSIONS:Results indicate that ADL corresponds to the progression of osteoporosis in postmenopausal women with hemiplegia and that increasing the level of ADL will reduce the progression of osteoporosis. Use of etidronate has also been proven to have a suppressive effect on the BMD decrease in women.

journal_name

Am J Phys Med Rehabil

authors

Ikai T,Uematsu M,Eun SS,Kimura C,Hasegawa C,Miyano S

doi

10.1097/00002060-200103000-00003

subject

Has Abstract

pub_date

2001-03-01 00:00:00

pages

169-74

issue

3

eissn

0894-9115

issn

1537-7385

journal_volume

80

pub_type

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