Ferritin iron absorption in man.

Abstract:

:The iron absorption from ferritin and hemosiderin biosynthetically labeled with radioiron was studied in 108 subjects. The geometric mean absorption of ferritin iron in both normal and iron-deficient subjects was 1.9 percent. Its mean absorption ranged from 0.9 percent in normal subjects to 2.5 percent in subjects with moderate iron deficiency and 5.7 percent in subjects with marked iron deficiency. The administration of this iron compound with vegetals in a meal showed distinctly lower absorption values than the absorption from either maize, wheat, or soybean. Ferritin iron absorption was also different from that of ferric chloride when they were administered together as a drink or mixed with maize or liver. The iron absorption from ferritin was markedly increased when it was administered with either meat or liver, but it did not reach the absorption level of these foods. It is still to be elucidated whether the difference in iron absorption between ferritin and vegetable foods administered together reflect that this iron is incompletely miscible with a nonheme iron pool or that it really forms a third iron pool.

journal_name

Blood

journal_title

Blood

authors

Layrisse M,Martínez-Torres C,Renzy M,Leets I

subject

Has Abstract

pub_date

1975-05-01 00:00:00

pages

689-98

issue

5

eissn

0006-4971

issn

1528-0020

journal_volume

45

pub_type

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