The application of image fusion in stereotactic brachytherapy of brain tumours.

Abstract:

BACKGROUND:The visualization of any morphological volume (i.e. CT, MRI) together with an additional second morphological volume (i.e. CT, MRI) or functional data set, which may come from SPECT or PET, is a new method for treatment planning, verification and follow-up of interstitial irradiation. METHOD:The authors present their experience on interstitial irradiation of brain tumours with stereotactically implanted I-125 seeds supported by image fusion. The image fusion was performed by the BrainLab-Target 1.13 software on Alfa 430 (Digital) workstation before, during, and after interstitial irradiation of brain tumours with Iodine125 seeds. RESULTS AND INTERPRETATION:On the basis of 20 brachytherapeutic image fusion of stereotactic CT (slices with fiducials) with additional stereotactic CT, MRI, PET and SPECT images provides more accurate and precise target volume, more exact localization of catheters and isotope seeds (verification fusion), differentiation between the localization and amount of the necrotic and proliferating parts of the tumours and shows the volume changes in consequence of interstitial irradiation. The image fusion should help to improve the accuracy and minimize the perifocal morbidity of interstitial irradiation.

journal_name

Acta Neurochir (Wien)

journal_title

Acta neurochirurgica

authors

Julow J,Major T,Emri M,Valálik I,Sági S,Mangel L,Németh G,Trón L,Várallyay G,Solymosi D,Hável J,Kiss T

doi

10.1007/s007010070022

subject

Has Abstract

pub_date

2000-01-01 00:00:00

pages

1253-8

issue

11

eissn

0001-6268

issn

0942-0940

journal_volume

142

pub_type

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