Polymorphisms in the Human SNAIL (SNAI1) gene.

Abstract:

:The human SNAIL is an important developmental protein involved in the formation of mesoderm and neural crest. The protein contains three classic and one atypical zinc-finger motif. The SNAI1 gene is composed of three exons. We have identified three SNPs in non-coding regions, two in the 5'UTR and one in intron 1, which can be detected by PCR followed by restriction enzyme digestion. We also identified a GGG/GGGG polymorphism in intron 1. We screened CEPH DNAs for these polymorphisms.

journal_name

Mol Cell Probes

authors

Okajima K,Paznekas WA,Burstyn T,Jabs EW

doi

10.1006/mcpr.2000.0332

subject

Has Abstract

pub_date

2001-02-01 00:00:00

pages

53-5

issue

1

eissn

0890-8508

issn

1096-1194

pii

S0890-8508(00)90332-3

journal_volume

15

pub_type

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