Effect of growth medium on potential of Streptomyces Anulatus spores to induce inflammatory responses and cytotoxicity in RAW264.7 macrophages.

abstract：:Tire and road wear particles (TRWP) are a component of ambient particulate matter (PM) produced from the interaction of tires with the roadway. Inhalation of PM has been associated with cardiopulmonary morbidities and mortalities thought to stem from pulmonary inflammation. To determine whether TRWP may contribute to ...

journal_title：Inhalation toxicology

authors： Kreider ML,Doyle-Eisele M,Russell RG,McDonald JD,Panko JM

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Gastroesophageal reflux of bile acids plays an important role in the development of Barrett's esophagus (BE)-associated esophageal adenocarcinoma (EAC). Cigarette smoke has been demonstrated to exacerbate the effects of reflux and thus the initial stages of EAC carcinogenesis. To date, no in vivo studies hav...

journal_title：Inhalation toxicology

authors： Aiyer HS,Li Y,Harper N,Myers SR,Martin RC

更新日期：2011-04-01 00:00:00

abstract：:To investigate effects of neurobehavioral disturbances in mice caused by sub-chronic exposure to low-dose volatile organic compounds (VOCs) and the possible mechanism for these effects, 60 male Kunming mice were exposed in 5 similar static chambers, 0 (control) and 4 different doses of VOCs mixture (G1-4) for consecut...

journal_title：Inhalation toxicology

authors： Wang F,Li C,Liu W,Jin Y

更新日期：2014-03-01 00:00:00

abstract：:The effect of prenatal exposure to diesel exhaust (DE) was investigated. Twenty pregnant ICR mice were exposed to DE at the particle concentration of 1.0 mg/m3, from d 2 until d 16 postcoitum. Male offspring were kept alive until 12 wk of age, and then male reproductive organ weight, daily sperm production (DSP), seru...

journal_title：Inhalation toxicology

authors： Ono N,Oshio S,Niwata Y,Yoshida S,Tsukue N,Sugawara I,Takano H,Takeda K

更新日期：2007-03-01 00:00:00

abstract：:Wistar rats were exposed for 24 mo to diesel emissions containing a low (0.2 ppm, 0.21 mg/m(3)), medium (1.04 ppm, 1.18 mg/m(3)), or high (2.96 ppm, 3.05 mg/m(3)) concentration of NO(2) and particles, or diesel emissions containing a medium (1.12 ppm, 0.01 mg/m(3)) concentration of NO(2) without particles. At 6-mo int...

journal_title：Inhalation toxicology

authors： Kato A,Nagai A,Kagawa J

更新日期：2000-06-01 00:00:00

abstract：:Acute lung injury (ALI) induced by phosgene increases risk of serious edema and mortality. Increased permeability of the microvascular endothelium is implicated in the progression of ALI, but the processing interaction and time course activity of the vascular regulators in exudation are still not understood. The main ...

journal_title：Inhalation toxicology

authors： Zhang XD,Hai CX,Cai FL,Liang X,Liu R,Chen HL,Qin XJ,Feng AJ

更新日期：2008-07-01 00:00:00

abstract：:Objective: Ethanol is used as a solvent for flavoring chemicals in some electronic cigarette (e-cigarette) liquids (e-liquids). However, there are limited data available regarding the effects of inhalation of ethanol on blood alcohol concentration (BAC) during e-cigarette use. In this study, a modified physiologically...

journal_title：Inhalation toxicology

authors： More SL,Thornton SA,Maskrey JR,Sharma A,de Gandiaga E,Cheng TJ,Fung ES,Bernal AJ,Madl AK

更新日期：2020-01-01 00:00:00

abstract：:Respiratory disturbances play a central role in chemical warfare nerve agent (CWNA) induced toxicity; they are the starting point of mass casualty and the major cause of death. We developed a microinstillation technique of inhalation exposure to nerve agent VX and assessed lung injury by biochemical analysis of the br...

journal_title：Inhalation toxicology

authors： Graham JR,Wright BS,Rezk PE,Gordon RK,Sciuto AM,Nambiar MP

更新日期：2006-06-01 00:00:00

abstract：:With growing evidence of the association between daily mortality and air pollution in adults, it is important to investigate whether infants are also susceptible to the adverse health effects of ambient air pollutants. The purpose of this study is to examine the relationship between air pollution and postneonatal mort...

journal_title：Inhalation toxicology

authors： Tsai SS,Chen CC,Hsieh HJ,Chang CC,Yang CY

更新日期：2006-03-01 00:00:00

abstract：CONTEXT:Heart rate alterations associated with exposure to particulate matter (PM) and gaseous pollutants have been observed in epidemiological studies and animal experiments. Nevertheless, the time-lag of these associations is still unclear. OBJECTIVE:Determine the association at different time-lags between the compl...

journal_title：Inhalation toxicology

authors： Ramos-Bonilla JP,Breysse PN,Dominici F,Geyh A,Tankersley CG

更新日期：2010-03-01 00:00:00

abstract：:Inhalation exposure systems are necessary tools for determining the dose-response relationship of inhaled toxicants under a variety of exposure conditions. The objective of this project was to develop an automated computer controlled system to expose small laboratory animals to precise concentrations of airborne multi...

journal_title：Inhalation toxicology

authors： McKinney W,Chen B,Frazer D

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVES:Rodents used in scientific research are typically housed in cages containing natural bedding materials. Despite extensive evidence of biological harm from inhaled particulate matter (PM), relatively little work has been performed to measure bedding-generated PM exposure in caged animals used in basic science...

journal_title：Inhalation toxicology

authors： Hudda N,Durant JL,Nemeth A,Mann P,Petitto J,Brugge D,Nephew BC

更新日期：2019-08-01 00:00:00

abstract：:In order to evaluate the chronic effect of polymerized toner particles on the lung, inflammation- and fibrosis-related genes were analyzed and 8-hydroxydeoxyguanosine (8-OHdG) was examined by using the lung tissue of rats subjected to 24 months of toner inhalation exposure. Wistar female rats were divided into four gr...

journal_title：Inhalation toxicology

authors： Morimoto Y,Hirohashi M,Kasai T,Oyabu T,Ogami A,Myojo T,Murakami M,Nishi K,Kadoya C,Todoroki M,Yamamoto M,Kawai K,Kasai H,Tanaka I

更新日期：2009-09-01 00:00:00

abstract：:Exposure to toluene, one of the major components of glue, can lead to cardiac arrhythmias and sudden sniffing death syndrome. QT dispersion is a useful risk marker for cardiac arrhythmias and sudden cardiac death. The aim of this study was to investigate the effects of glue abuse on QT interval and QT dispersion. The ...

journal_title：Inhalation toxicology

authors： Alper AT,Akyol A,Hasdemir H,Nurkalem Z,Güler O,Güvenç TS,Erdinler I,Cakmak N,Eksik A,Gürkan K

更新日期：2008-01-01 00:00:00

abstract：:Halomethanes (HMs) can be formed during the chlorination process to obtain drinking water. In liver cells, HMs had been shown to be mutagenic and carcinogenic; however, their bioactivation by CYP 2E1 and GSTT1 is required. Although inhalation is the most common pathway of exposure, reports on the toxic effects induced...

journal_title：Inhalation toxicology

authors： Nájera-Martínez M,García-Latorre EA,Reyes-Maldonado E,Domínguez-López ML,Vega-López A

更新日期：2012-09-01 00:00:00

abstract：:The understanding of historical ambient asbestos concentrations is critical to exposure mapping and retrospective health impact studies involving asbestos related diseases. Two presentations at the University of Montana Center for Environmental Health Sciences Asbestos Conference (July 28, 2005) introduced novel metho...

journal_title：Inhalation toxicology

authors： Webber JS,Getman M,Ward TJ

更新日期：2006-11-01 00:00:00

abstract：:In February 2006, an IARC Monographs Working Group reevaluated the carcinogenic hazards to humans of carbon black, titanium dioxide, and talc, which belong to the group of poorly soluble, low-toxicity particles. The review of the relevant literature and the evaluations by the Working Group will be published in Volume ...

journal_title：Inhalation toxicology

authors： Baan RA

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Increases in particulate matter less than 2.5 µm (PM(2.5)) in ambient air is linked to acute cardiovascular morbidity and mortality. Specific components and potential emission sources of PM(2.5) responsible for adverse health effects of cardiovascular function are unclear. METHODS:Spontaneously hypertensive...

journal_title：Inhalation toxicology

authors： Kamal AS,Rohr AC,Mukherjee B,Morishita M,Keeler GJ,Harkema JR,Wagner JG

更新日期：2011-06-01 00:00:00

abstract：:Epidemiological studies have reported increased morbidity in human populations following inhalation of elevated levels of urban particulate matter. These responses are especially prevalent in populations with chronic obstructive pulmonary diseases, including chronic bronchitis. Toxicological studies have reported alte...

journal_title：Inhalation toxicology

authors： Clarke RW,Catalano PJ,Koutrakis P,Murthy GG,Sioutas C,Paulauskis J,Coull B,Ferguson S,Godleski JJ

更新日期：1999-08-01 00:00:00

abstract：:In order to conserve material that is available in limited quantities, "directed-flow" nose-only exposure systems have at times been run at flow rates close to the minute ventilation of the animal. Such low-flow-rate conditions can contribute to a decrease of test substance concentration in inhaled air; near the anima...

journal_title：Inhalation toxicology

authors： Moss OR,James RA,Asgharian B

更新日期：2006-01-01 00:00:00

abstract：:It is important to conduct a risk assessment that includes hazard assessment and exposure assessment for the safe production and handling of newly developed nanomaterials. We conducted an inhalation study of a multi-wall carbon nanotube (MWCNT) as a hazard assessment. Male Wistar rats were exposed to well-dispersed MW...

journal_title：Inhalation toxicology

authors： Oyabu T,Myojo T,Morimoto Y,Ogami A,Hirohashi M,Yamamoto M,Todoroki M,Mizuguchi Y,Hashiba M,Lee BW,Shimada M,Wang WN,Uchida K,Endoh S,Kobayashi N,Yamamoto K,Fujita K,Mizuno K,Inada M,Nakazato T,Nakanishi J,Tanaka

更新日期：2011-11-01 00:00:00

abstract：:The Toxicological Evaluation of Realistic Emissions Source Aerosols (TERESA) study was carried out at three US coal-fired power plants to investigate the potential toxicological effects of primary and photochemically aged (secondary) particles using in situ stack emissions. The exposure system designed successfully si...

journal_title：Inhalation toxicology

authors： Kang CM,Gupta T,Ruiz PA,Wolfson JM,Ferguson ST,Lawrence JE,Rohr AC,Godleski J,Koutrakis P

更新日期：2011-08-01 00:00:00

abstract：OBJECTIVE:Dimethyl sulfide (DMS, CAS 75-18-3) is an industrial chemical. It is both an irritant and neurotoxicant that may be life-threatening because of accidental release. The effects of DMS on public health and associated public health response depend on the exposure concentration and duration. However, currently, p...

journal_title：Inhalation toxicology

authors： Demchuk E,Ball SL,Le SL,Prussia AJ

更新日期：2018-01-01 00:00:00

abstract：:Washed human erythrocytes were incubated with titanium dioxide (TiO2) particles at 37 degrees C for 1 hr and hemolysis was determined by the percentage of hemoglobin released (optical density at 540 nm; OD540) from the cells. Effects of TiO2 on OD540 were corrected and dose-response curves were analyzed by the Hill pl...

journal_title：Inhalation toxicology

authors： Aisaka Y,Kawaguchi R,Watanabe S,Ikeda M,Igisu H

更新日期：2008-07-01 00:00:00

abstract：:We used inert melamin particles that are very well defined in size (diameters: 0.5, 1.9, 6.8 microm) to study the effects of ambient particles of <10 microm (PM(10)) on phagocytosis. Dose-response functions were found between the amount of added melamin particle mass and the toxicity. Fine particles (0.5 microm) were ...

journal_title：Inhalation toxicology

authors： Monn C,Fendt R,Koller T

更新日期：2002-04-01 00:00:00

abstract：:Wollastonite is a naturally occurring calcium silicate (CaSiO(3)) that is produced in both powder and fibrous forms. It is a valuable industrial mineral used in plastics, ceramics, metallurgical applications, paint, and friction products. For some applications wollastonite serves as an asbestos replacement. To varying...

journal_title：Inhalation toxicology

authors： Maxim LD,McConnell EE

更新日期：2005-08-01 00:00:00

abstract：:Species differences in the handling of particles are topics of interest for setting ambient particulate matter standards as well as for studies involving the phenomenon of lung overload and the implications, if any, of such studies for workplace dust exposure standards. The dosimetry of inhaled particles differs among...

journal_title：Inhalation toxicology

authors： Miller FJ

更新日期：2000-01-01 00:00:00

abstract：:Recent studies have shown that air pollution is a risk factor for hospitalization for pneumonia. However, there is limited evidence to suggest what subpopulations are at greater risk from air pollution. This study was undertaken to examine the modifying effect of specific secondary diagnosis (including hypertension, d...

journal_title：Inhalation toxicology

authors： Cheng MF,Tsai SS,Chiu HF,Sung FC,Wu TN,Yang CY

更新日期：2009-11-01 00:00:00

abstract：:The World Health Organization identified urban outdoor air pollution as the eighth highest mortality risk factor in high-income countries. Exposure to ambient pollutants such as ozone (O3) increases the number of hospital admissions. O3 is a highly reactive gas that reacts with cells lining the airways, producing the ...

journal_title：Inhalation toxicology

authors： González-Guevara E,Martínez-Lazcano JC,Custodio V,Hernández-Cerón M,Rubio C,Paz C

更新日期：2014-07-01 00:00:00

abstract：:Nasal efficiency for removing fine particles from inhaled air may be affected by variations in nasal structure associated with race. In 11 African American and 11 Caucasian adults (age 18-31 yr) we measured the fractional deposition (DF) of fine particles (1 and 2 mum mass median aerodynamic diameter) (MMAD) for oral ...

journal_title：Inhalation toxicology

authors： Bennett WD,Zeman KL

更新日期：2005-11-01 00:00:00