Abstract:
:Hantaan (HTN) virus, the etiologic agent of clinically severe hemorrhagic fever with renal syndrome (HFRS), was first isolated in 1976 from lung tissues of striped field mice (Apodemus agrarius) captured in Songnae-ri, Kyungki-do, Korea. To clarify the genetic diversity and phylogenetic relationship among Korean strains of HTN virus, viral sequences of the partial S and M segments were amplified from lung tissues of 24 seropositive striped field mice captured between 1989 and 1998 at 11 sites in South Korea. The 771-nucleotide (nt) S segment sequences (coordinates 432 to 1202) of HTN virus strains from Yangju-kun differed by 10 to 40 nt (1.3 to 5.2%) from virus strains from Pocheon-kun, Songnae-ri and Nonsan-kun. Similar degrees of genetic variation were found in the G1 and G2 glycoprotein-encoding M segment. Phylogenetic trees, based on the partial S and M segments and generated by the maximum parsimony and neighbor-joining methods, demonstrated that virus strains from various geographic regions in South Korea showed a tendency to form two phylogenetic subgroups and were evolutionarily distinct from HTN virus strains from the People's Republic of China.
journal_name
Virus Genesjournal_title
Virus genesauthors
Song JW,Baek LJ,Kim SH,Kho EY,Kim JH,Yanagihara R,Song KJdoi
10.1023/a:1008199800011subject
Has Abstractpub_date
2000-10-01 00:00:00pages
227-32issue
3eissn
0920-8569issn
1572-994Xjournal_volume
21pub_type
杂志文章相关文献
VIRUS GENES文献大全abstract::The 5' non-coding region (5'-NCR) of 27 classical swine fever virus (CSFV) isolates from Lao People's Democratic Republic (Lao PDR) during 1997 and 1999 were amplified by RT-PCR. A 150-bp region of the 5'-NCR amplicons was analysed and compared with reference CSFV of European and Asian origin and a phylogenetic dendro...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-005-3253-0
更新日期:2005-12-01 00:00:00
abstract::Boid inclusion body disease (BIBD) is a viral disease of boids caused by reptarenavirus. In this study, tissue from naturally infected boid snakes were homogenized and propagated in African Monkey kidney (Vero) and rat embryonic fibroblast (REF) cells. Virus replication was determined by the presence of cytopathic eff...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-016-1345-7
更新日期:2016-10-01 00:00:00
abstract::A bovine viral diarrhea disease virus (BVDV) GS-4 was isolated in Western China form dairy cattle with respiratory disease. Genomic comparison analysis with the 5' half genome sequence encompassing the coding region of N(pro), capsid, and envelope glycoproteins showed that the GS-4 should be classified into BVDV-1b1, ...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-013-0917-z
更新日期:2013-08-01 00:00:00
abstract::Currently, virus-based vectors, namely derivatives of the adenovirus, are frequently used in a wide variety of ex vivo or local gene therapeutic applications. However, the efficacy of virus-based vectors in systemic applications is presently still extremely limited. Complex interactions of the various vector types wit...
journal_title:Virus genes
pub_type: 杂志文章,评审
doi:10.1007/s11262-017-1498-z
更新日期:2017-10-01 00:00:00
abstract::Proteins harbor domains or short linear motifs, which facilitate their functions and interactions. Finding functional motifs in protein sequences could predict the putative cellular roles or characteristics of hypothetical proteins. In this study, we present Shetti-Motif, which is an interactive tool to (i) map UniPro...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-016-1416-9
更新日期:2017-04-01 00:00:00
abstract::Recently, we reported that the frequency of hepatitis C virus (HCV) genotypes and subtypes has rapidly changed among intravenous drug users (IDUs) in Yunnan Province over the last 5 years; this is especially true for subtype 6a which has increased in frequency from 5 to 15%. Here, we assessed 120 HCV-positive plasma s...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-016-1420-0
更新日期:2017-04-01 00:00:00
abstract::Although Sapovirus (Caliciviridae) has been accepted as one of the causes of acute gastroenteritis worldwide, little is known about the genetic characteristics of the whole genome of sapoviruses in China, especially those that infect humans. Here we report the complete genome sequence of a sapovirus strain, Human/Zhej...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-016-1343-9
更新日期:2016-10-01 00:00:00
abstract::A low-cost rodent model of HIV infection and which presents high application value is an effective tool to investigate HIV infection and pathogenesis. However, development of such a small animal model has been hampered by the unsuitability of rodent cells for HIV-1 replication given that the retrovirus HIV-1 has high ...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-016-1423-x
更新日期:2017-04-01 00:00:00
abstract::Straw-colored fruit bats (Eidolon helvum), which have been identified as natural hosts for several zoonotic pathogens, such as lyssaviruses, henipaviruses, and ebolavirus, are associated with human settlements in Nigeria where they are commonly consumed as a delicacy. However, information on the viruses harbored by th...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-016-1331-0
更新日期:2016-08-01 00:00:00
abstract::Protein 2A is a non-structural protein of coxsackievirus B3 (CVB3), an important human pathogen that can cause a variety of human diseases. Protein 2A not only participates in viral life cycle, but also regulates host cell functions; however, the underlying mechanisms remain poorly understood. In order to better under...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-015-1270-1
更新日期:2016-04-01 00:00:00
abstract::Two ribozyme genes were designed to cut within the VP4 and VP3 sequences of foot and mouth disease virus (FMDV) Asia1 serotype genome. The two genes were synthesized and cloned into pBluescript under the control of the T3 promoter. The ribozyme designed to cut the VP4 gene contained two catalytic sequences targeted to...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/BF01702658
更新日期:1995-01-01 00:00:00
abstract::Orf virus (ORFV), a typical member of the Parapoxvirus genus within the family Poxviridae, which is the causative agent of Orf, a common epitheliotropic viral disease of sheep, goats, wild ruminants, and humans. In the present study, we sequenced the complete genomic sequences of two ORFV strains (ORFV-SY17, isolated ...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-019-01666-y
更新日期:2019-08-01 00:00:00
abstract::Brazil is one of the largest silk producers in the world. The domesticated silkworm (Bombyx mori) was formally introduced into the country in the twentieth century, and the state of Paraná is the main national producer. During larval stages, B. mori can be afflicted by many different infectious diseases, which lead to...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-014-1112-6
更新日期:2014-12-01 00:00:00
abstract::Orf virus (ORFV) strain D1701-V, a Parapoxvirus belonging to the family Poxviridae, became attractive as a novel virus vector system that we successfully used for the generation of recombinant vaccines. Therefore, the identification of viral genes involved in host tropisms or immune modulation is of great interest, as...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-014-1069-5
更新日期:2014-08-01 00:00:00
abstract::Coxsackieviruses are important human pathogens that induce myocarditis and pancreatitis. However, there are no vaccines or therapeutic reagents for their clinical treatment. Although RNA interference (RNAi)-based approaches to the prevention of viral production have been developed recently, limitations to the in vivo ...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-007-0192-y
更新日期:2008-02-01 00:00:00
abstract::The genomes (188 kbp) of the prototype Molluscum contagiosum virus type 1 (MCV-1) and a variant strain (MCV-1v) were characterized by construction of the physical maps of the viral DNA for the restriction enzymes BamHI, ClaI, EcoRI, and HindIII using a defined gene library harboring the DNA sequences of the MCV-1 geno...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/BF00125128
更新日期:1989-11-01 00:00:00
abstract::Cauliflower mosaic virus (CaMV) gene I encodes a protein (P1) that has been implicated in the control of virus movement in infected plants. To assist in the characterization of the mechanism of action of P1, gene I has been expressed efficiently in Spodoptera frugiperda (Sf) cells using recombinant baculovirus. Contro...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/BF01703753
更新日期:1992-01-01 00:00:00
abstract::H1 influenza A viruses that were distinct from the classical swine H1 lineage were identified in pigs in Canada in 2003–2004; antigenic and genetic characterization identified the hemagglutinin (HA) as human H1 lineage. The viruses identified in Canadian pigs were human lineage in entirety or double (human–swine) reas...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-009-0386-6
更新日期:2009-10-01 00:00:00
abstract::Novel duck reovirus (NDRV), the prototype strain of the species Avian orthoreovirus (ARV), is associated with high mortality in Pekin ducklings. σC is an outer capsid protein encoded by the S1 genome segment of NDRV which mediates attachment to host cells. Our previous studies using immunoprecipitation and mass spectr...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-020-01750-8
更新日期:2020-06-01 00:00:00
abstract::Nitric oxide (NO) has been shown to suppress Japanese encephalitis virus (JEV) RNA synthesis, viral protein accumulation, and virus release from infected cells. In this article, the potential viral structural proteins as the activators of NO product were studied at the molecular level. First, the genomic region encodi...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-008-0299-9
更新日期:2009-02-01 00:00:00
abstract::Enterovirus 96 (EV-96) is a recently described member of the species Enterovirus C and is associated with paralysis and myelitis. In this study, using metagenomic sequencing, we identified a new enterovirus 96 strain (EV-96-SZ/GD/CHN/2014) as the sole pathogen causing hand, foot, and mouth disease (HFMD). A genomic co...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-017-1431-5
更新日期:2017-06-01 00:00:00
abstract::Glycosylation on the globular head of the hemagglutinin (HA) protein of influenza virus acts as an important target for recognition and destruction of virus by innate immune proteins of the collectin family. In the current study, we have characterized the dynamic amino acid changes at N-linked glycosylation sites of f...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-013-0993-0
更新日期:2014-02-01 00:00:00
abstract::Porcine reproductive and respiratory syndrome (PRRS) is considered to be one of the most important infectious diseases affecting livestock. This study used gene sequence analysis of ORF5 and Nsp2 to determine the molecular epidemiology of PRRSV in different parts of the Guangxi province of China. These genes were sele...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-012-0824-8
更新日期:2013-02-01 00:00:00
abstract::Herpesvirus saimiri induces acute lymphomas and leukemias in primates and rabbits. Sequence divergence of the right end unique region of the genome classifies virus strains into three groups (A, B, and C), and previous studies have demonstrated correlation between DNA grouping and oncogenicity. In order to relate diff...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/BF01703599
更新日期:1994-01-01 00:00:00
abstract::The genome of equine arteritis virus (EAV) produces a 3' coterminal-nested set of six subgenomic (sg) viral RNAs during virus replication cycle, and each set possesses a common leader sequence of 206 nucleotides (nt) in length derived from the 5' end of the viral genome. Given the presence of the leader region within ...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-004-4589-6
更新日期:2005-01-01 00:00:00
abstract::Hepatitis C virus (HCV) infection is a major global health issue. Although the search for HCV treatments has resulted in great achievements, the current treatment methods have limitations, and new methods and drugs for hepatitis C treatment are still required. The aim of the present study was to investigate the effect...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-015-1285-7
更新日期:2016-02-01 00:00:00
abstract::Acinetobacter pittii is an important pathogen causing nosocomial infection worldwide. In this study, a multidrug-resistant A. pittii ABC38 was used as host bacterium to isolate the lytic phage vB_ApiP_XC38. The biological characteristics of vB_ApiP_XC38 were studied and the genome was sequenced and analyzed. vB_ApiP_X...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/s11262-020-01766-0
更新日期:2020-08-01 00:00:00
abstract::Virus-like particles (VLPs, named HmTV1-17), about 40 nm in diameter were found in the violet root rot fungus Helicobasidium mompa Tanaka strain No. 17, which had been isolated from an apple tree. Purified preparations of HmTV1-17 contained two species of double-stranded RNA (dsRNA), designated 17L and 17S. cDNAs were...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1023/a:1024453111809
更新日期:2003-05-01 00:00:00
abstract::The threat of highly virulent avian influenza, such as H5N1 and swine-origin H1N1 influenza viruses, bring out an urgent need to develop a universal influenza vaccine, which may provide cross-protection against different strain of influenza A viruses. The extra-domain of influenza M2 protein (M2e), which is almost com...
journal_title:Virus genes
pub_type: 杂志文章,评审
doi:10.1007/s11262-010-0547-7
更新日期:2011-02-01 00:00:00
abstract::We have extended our studies using the mouse lymphoid cell system to determine if polyomavirus (Py) cell type specificity is a consequence of the simple presence of either the A and B enhancers, or if specificity results from specific combinations or arrangements of the individual enhancer elements. Mouse fibroblasts ...
journal_title:Virus genes
pub_type: 杂志文章
doi:10.1007/BF00125683
更新日期:1987-11-01 00:00:00