The production of superantigenic exotoxins by coagulase-negative staphylococci isolated from human skin lesions.

Abstract:

:We examined the production of superantigenic exotoxins in 136 coagulase-negative staphylococci isolated from various skin lesions in humans using a reversed passive latex agglutination test (Denka Seiken). As a control we examined the same in 50 Staphylococcus aureus strains isolated from non-infective skin ulcers in humans. Of the 136 strains of coagulase negative-staphylococci, 9 (6.6%) produced one or more identifiable exotoxins. In contrast, 21 (42%) out of the 50 S. aureus strains produced one or more identifiable exotoxins (P<0.01).

journal_name

J Dermatol Sci

authors

Akiyama H,Yamasaki O,Tada J,Arata J

doi

10.1016/s0923-1811(00)00122-5

subject

Has Abstract

pub_date

2000-11-01 00:00:00

pages

142-5

issue

2

eissn

0923-1811

issn

1873-569X

pii

S0923-1811(00)00122-5

journal_volume

24

pub_type

杂志文章
  • Glutathione in human melanoma cells. Effects of cysteine, cysteine esters and glutathione isopropyl ester.

    abstract::Thiols are of great importance for the regulation of many cellular functions including metabolism, transport and cell protection. In this study the usefulness of L-cysteine methyl and octyl esters, of N,S-diacetyl-L-cysteine methyl ester and glutathione isopropyl ester as cellular cysteine and GSH delivery systems was...

    journal_title:Journal of dermatological science

    pub_type: 杂志文章

    doi:10.1016/0923-1811(90)90008-2

    authors: Karg E,Tunek A,Brötell H,Hallberg A,Rosengren E,Rorsman H

    更新日期:1990-01-01 00:00:00

  • Effects of kestose on gut mucosal immunity in an atopic dermatitis mouse model.

    abstract:BACKGROUND:Atopic dermatitis (AD) is recently increasing among populations, but the underlying mechanisms remain controversial. Interactions between the gut microbiota and mucosal immunity are considered to be a crucial etiology. Fructooligosaccharide (FOS), prebiotics have been reported as activators of the gut microb...

    journal_title:Journal of dermatological science

    pub_type: 杂志文章

    doi:10.1016/j.jdermsci.2017.10.006

    authors: Kim HJ,Lee SH,Go HN,Ahn JR,Kim HJ,Hong SJ

    更新日期:2018-01-01 00:00:00

  • Cloning of the hamster androgen receptor gene.

    abstract::Flank organs of male Golden Syrian hamsters contain sebaceous glands and hair follicles whose morphology and function are highly dependent on androgen, which makes these organs a useful model to study androgen action. In order to investigate molecular mechanisms of androgen action, we cloned a cDNA encoding the hamste...

    journal_title:Journal of dermatological science

    pub_type: 杂志文章

    doi:10.1016/s0923-1811(00)00172-9

    authors: Shiba K,Hamaguchi T,Kataoka K,Yamaguchi Y,Handa H,Adachi K

    更新日期:2001-07-01 00:00:00

  • Tumor-associated M2 macrophages in mycosis fungoides acquire immunomodulatory function by interferon alpha and interferon gamma.

    abstract:BACKGROUND:Tumor-associated M2 macrophages (TAMs) produce chemokines that affect the formation of cutaneous T-cell lymphoma (CTCL) by stromal factors. Since IFNs are an effective treatment for advanced-stage mycosis fungoides (MF), we hypothesized that IFNs might modulate M2 macrophages. OBJECTIVE:To prove our hypothe...

    journal_title:Journal of dermatological science

    pub_type: 杂志文章

    doi:10.1016/j.jdermsci.2016.05.004

    authors: Furudate S,Fujimura T,Kakizaki A,Hidaka T,Asano M,Aiba S

    更新日期:2016-09-01 00:00:00

  • Sequence analysis and characterization of FAR-17c, an androgen-dependent gene in the flank organs of hamsters.

    abstract::This study reports on the isolation and characterization of a cDNA clone, regulated by androgen transcriptionally, in male Golden hamsters' flank organs. Previous studies have reported on the cloning of an androgen-dependent gene, FAR-17a, from the same hamster organ. After castration, the FAR-17c transcription rate d...

    journal_title:Journal of dermatological science

    pub_type: 杂志文章

    doi:10.1016/0923-1811(94)00357-k

    authors: Ideta R,Seki T,Adachi K

    更新日期:1995-03-01 00:00:00

  • Immunohistochemical evaluation of tenascin in benign eccrine gland tumors: comparison with laminin and fibronectin.

    abstract::Surgically resected specimens of skin appendage tumors, spiradenoma, poroma of eccrine glands, syringoadenoma, syringoadenoma papilliferum and mixec tumor of skin were evaluated for tenascin, as well as the basement membrane-associated protein laminin, and the extracellular matrix protein fibronectin, using immunohist...

    journal_title:Journal of dermatological science

    pub_type: 杂志文章

    doi:10.1016/0923-1811(94)00369-p

    authors: Mori M,Shrestha P,Takagi H,Ogata K,Takai Y

    更新日期:1995-03-01 00:00:00

  • Both Th2 and Th1 chemokines (TARC/CCL17, MDC/CCL22, and Mig/CXCL9) are elevated in sera from patients with atopic dermatitis.

    abstract:BACKGROUND:Chemokines and their receptors are important elements for the selective attraction and activation of various subsets of leukocytes. Expression of CXCR3 ligands, such as monokine induced by IFN-gamma (Mig) leads to preferential Th1 recruitment, whereas CCR4 ligands, thymus and activation regulated chemokine (...

    journal_title:Journal of dermatological science

    pub_type: 杂志文章

    doi:10.1016/j.jdermsci.2004.01.001

    authors: Shimada Y,Takehara K,Sato S

    更新日期:2004-05-01 00:00:00

  • Keratinocyte growth factor and keratin gene regulation.

    abstract::Keratinocyte growth factor (KGF) is a stromally derived paracrine mitogen that belongs to the fibroblast growth factor (FGF) family. It is secreted by dermal fibroblasts and specifically promotes keratinocyte proliferation. We have recently shown that epidermal growth factor (EGF) and transforming growth factor beta (...

    journal_title:Journal of dermatological science

    pub_type: 杂志文章

    doi:10.1016/0923-1811(94)00350-n

    authors: Latkowski JM,Freedberg IM,Blumenberg M

    更新日期:1995-01-01 00:00:00

  • The role of immunohistochemistry in the diagnosis of the non-lethal forms of junctional epidermolysis bullosa.

    abstract::Skin biopsies from four patients with similar clinical phenotypes of non-lethal junctional epidermolysis bullosa (JEB) were investigated by electron microscopy and immunohistochemistry. Electron microscopy revealed cleavage within the lamina lucida in each case, but in addition, there was considerable variability in t...

    journal_title:Journal of dermatological science

    pub_type: 杂志文章

    doi:10.1016/s0923-1811(96)00554-3

    authors: McGrath JA,Eady RA

    更新日期:1997-01-01 00:00:00

  • Epidermal turnover time.

    abstract::Epidermal turnover time is the time taken for the epidermis to replace itself. The turnover time can be subdivided; when the epidermis is divided into proliferative compartment, differentiated compartment, and stratum corneum, the total turnover time is the sum of the turnover time of each compartment. Using Weinstein...

    journal_title:Journal of dermatological science

    pub_type: 杂志文章

    doi:10.1016/0923-1811(94)90057-4

    authors: Iizuka H

    更新日期:1994-12-01 00:00:00

  • Cultured keratinocytes from plectin/HD1-deficient epidermolysis bullosa simplex showed altered ability of adhesion to the matrix.

    abstract::Epidermolysis bullosa simplex associated with late onset of muscular dystrophy has been found to show defective expression of plectin, an intracytoplasmic protein in hemidesmosomes. In this report, we examined ability of cell-to-matrix attachment of cultured keratinocytes derived from a case with this disease by vario...

    journal_title:Journal of dermatological science

    pub_type: 杂志文章

    doi:10.1016/s0923-1811(00)00100-6

    authors: Kurose K,Mori O,Hachisuka H,Shimizu H,Owaribe K,Hashimoto T

    更新日期:2000-12-01 00:00:00

  • The Yucatan miniature swine as an in vivo model for screening skin depigmentation.

    abstract::The usefulness of the Yucatan miniature pig as a screen for skin dipigmenting activity by topical application was evaluated with standard compounds. This is a naturally occurring breed of swine with light brown to dark brown skin that is relatively hairless. The skin morphology, including the pattern of pigment distri...

    journal_title:Journal of dermatological science

    pub_type: 杂志文章

    doi:10.1016/0923-1811(91)90007-k

    authors: Nair X,Tramposch KM

    更新日期:1991-12-01 00:00:00

  • Update on contact dermatitis 2007: Medical pearls from the annual meeting of the British Contact Dermatitis Society at the annual meeting of the British Association of Dermatologists.

    abstract::Contact dermatitis is an integral part of dermatology. Many patients affected by contact dermatitis suffer significant morbidity and require prompt diagnosis and treatment. Here we give an overview of contact dermatitis related presentations made during the British Contact Dermatitis Society at 87th annual meeting of ...

    journal_title:Journal of dermatological science

    pub_type:

    doi:10.1016/j.jdermsci.2008.02.002

    authors: Alexandroff AB,Gawkrodger DJ

    更新日期:2008-09-01 00:00:00

  • Involvement of the lipoprotein receptor LRP1 in AMP-IBP5-mediated migration and proliferation of human keratinocytes and fibroblasts.

    abstract:BACKGROUND:Antimicrobial peptide derived from insulin-like growth factor binding protein-5 (AMP-IBP5) is a potent antimicrobial agent that possesses various immunomodulatory activities. The parent protein of AMP-IBP5, IGFBP-5, has been shown to exert its effects via an insulin-like growth factor-1 receptor-independent ...

    journal_title:Journal of dermatological science

    pub_type: 杂志文章

    doi:10.1016/j.jdermsci.2020.07.003

    authors: Chieosilapatham P,Yue H,Ikeda S,Ogawa H,Niyonsaba F

    更新日期:2020-09-01 00:00:00

  • miR-128 targets the CC chemokine ligand 18 gene (CCL18) in cutaneous malignant melanoma progression.

    abstract:BACKGROUND:The CC chemokine ligand 18 (CCL18) has a higher expression in some tumors, while the CCL18 level can be a marker of tumor progression and prognosis. We previously reported that the expression of CCL18 gene was dramatically up-regulated in cutaneous malignant melanoma (CMM) and its expression levels were corr...

    journal_title:Journal of dermatological science

    pub_type: 杂志文章

    doi:10.1016/j.jdermsci.2018.06.011

    authors: Song H,Tao Y,Ni N,Zhou X,Xiong J,Zeng X,Xu X,Qi J,Sun J

    更新日期:2018-09-01 00:00:00

  • Ultraviolet irradiation-induced inhibition of histone deacetylase 4 increases the expression of matrix metalloproteinase-1 but decreases that of type I procollagen via activating JNK in human dermal fibroblasts.

    abstract:BACKGROUND:Ultraviolet (UV) irradiation is the main contributing factor for skin aging. UV irradiation induces epigenetic changes in skin. It increases the activity of histone acetylases (HATs) but decreases that of histone deacetylases (HDACs). OBJECTIVE:We aimed to investigate alterations in all classes of HDACs and...

    journal_title:Journal of dermatological science

    pub_type: 杂志文章

    doi:10.1016/j.jdermsci.2020.11.008

    authors: Lee Y,Shin MH,Kim MK,Park CH,Shin HS,Lee DH,Chung JH

    更新日期:2020-12-03 00:00:00

  • Resolvin D1 attenuates imiquimod-induced mice psoriasiform dermatitis through MAPKs and NF-κB pathways.

    abstract:BACKGROUND:Resolvin D1 (RvD1), a pro-resolution lipid mediator derived from docosahexaenoic acid (DHA), has been described to promote several kinds of inflammatory resolution. However, the effects and anti-inflammatory mechanisms of RvD1 on psoriasis have not been previously reported. OBJECTIVE:The present study aimed...

    journal_title:Journal of dermatological science

    pub_type: 杂志文章

    doi:10.1016/j.jdermsci.2017.10.016

    authors: Xu J,Duan X,Hu F,Poorun D,Liu X,Wang X,Zhang S,Gan L,He M,Zhu K,Ming Z,Chen H

    更新日期:2018-02-01 00:00:00

  • A novel niche for skin derived precursors in non-follicular skin.

    abstract:BACKGROUND:Skin derived precursors (SKP) comprise a subset of specialized dermal cells that can be distinguished from fibroblast by their capacity for spheroidal growth. Recent investigations have shown that hair follicles constitute a niche for this cell type, but their localization and their definite function in non-...

    journal_title:Journal of dermatological science

    pub_type: 杂志文章

    doi:10.1016/j.jdermsci.2012.10.007

    authors: Ruetze M,Knauer T,Gallinat S,Wenck H,Achterberg V,Maerz A,Deppert W,Knott A

    更新日期:2013-02-01 00:00:00

  • Effect of cyclosporin A on suppressor T cells.

    abstract::The effect of cyclosporin A (CsA) on suppressor T cells (Ts) was evaluated by in vitro incubation with afferent-phase Ts (Ts-aff) and efferent-phase Ts (Ts-eff). 2,4-Dinitro-1-fluorobenzene (DNFB) and hen egg-white lysozyme (HEL) were used as antigens. Both Ts-aff and Ts-eff were resistant to high- and low-dose CsA tr...

    journal_title:Journal of dermatological science

    pub_type: 杂志文章

    doi:10.1016/0923-1811(90)90218-3

    authors: Ishii N,Ishii H,Ono H,Horiuchi Y,Nakajima H,Aoki I

    更新日期:1990-03-01 00:00:00

  • rAAV2-mediated restoration of LEKTI in LEKTI-deficient cells from Netherton patients.

    abstract:BACKGROUND:Netherton syndrome (NS, MIM 256500) is a potential live threatening autosomal-recessive skin disorder clinically characterized by the trias of congenital erythroderma, hair shaft anomalies and atopic diathesis. It is caused by mutations in the gene SPINK5 resulting in a deficiency of its processed protein na...

    journal_title:Journal of dermatological science

    pub_type: 杂志文章

    doi:10.1016/j.jdermsci.2010.12.004

    authors: Roedl D,Oji V,Buters JT,Behrendt H,Braun-Falco M

    更新日期:2011-03-01 00:00:00

  • Spatial data analysis by epidermal Langerhans cells reveals an elegant system.

    abstract::Langerhans cells are dendritic cells situated in the mammalian epidermis. In human epidermis, the concentration is between 460 and 1000 mm(-2). Langerhans cells fulfill an essential role in skin immune responses. Numerous scientific reports on Langerhans cells have appeared, but with no systematic research on the patt...

    journal_title:Journal of dermatological science

    pub_type: 杂志文章

    doi:10.1016/s0923-1811(00)00129-8

    authors: Numahara T,Tanemura M,Nakagawa T,Takaiwa T

    更新日期:2001-04-01 00:00:00

  • Identification of mutations in the prostaglandin transporter gene SLCO2A1 and its phenotype-genotype correlation in Japanese patients with pachydermoperiostosis.

    abstract:BACKGROUND:Pachydermoperiostosis (PDP) is a rare genetic disorder characterized by 3 major symptoms: pachydermia including cutis verticis gyrata (CVG), periostosis, and finger clubbing. Recently, a homozygous mutation in the gene HPGD, which encodes 15-hydroxyprostaglandin dehydrogenase (15-PGDH), was found to be assoc...

    journal_title:Journal of dermatological science

    pub_type: 杂志文章

    doi:10.1016/j.jdermsci.2012.07.008

    authors: Sasaki T,Niizeki H,Shimizu A,Shiohama A,Hirakiyama A,Okuyama T,Seki A,Kabashima K,Otsuka A,Ishiko A,Tanese K,Miyakawa S,Sakabe J,Kuwahara M,Amagai M,Okano H,Suematsu M,Kudoh J

    更新日期:2012-10-01 00:00:00

  • Differential down-regulation of COX-2 and MMP-13 in human skin fibroblasts by glucosamine-hydrochloride.

    abstract:BACKGROUND:Evidence suggests anti-inflammatory effects of glucosamine (GS) on inflammatory diseases. COX-2 is an enzyme to produce prostaglandins. MMPs are the family of matrix metalloproteinases degradable of ECM. Excess expression of COX-2 or MMPs involves in skin inflammation. OBJECTIVE:We evaluated whether GS-HCl ...

    journal_title:Journal of dermatological science

    pub_type: 杂志文章

    doi:10.1016/j.jdermsci.2009.06.017

    authors: Hong H,Park YK,Choi MS,Ryu NH,Song DK,Suh SI,Nam KY,Park GY,Jang BC

    更新日期:2009-10-01 00:00:00

  • A lamellar body mimetic system for the treatment of oxazolone-induced atopic dermatitis in hairless mice.

    abstract:BACKGROUND:Atopic dermatitis is a common skin disease characterized by a Th2 cell-dominant inflammatory infiltrate, elevated serum IgE levels and impaired epidermal barrier function. It is associated to abnormal epidermal lamellar body secretion, producing alteration in lipid composition and extracellular lamellar memb...

    journal_title:Journal of dermatological science

    pub_type: 杂志文章

    doi:10.1016/j.jdermsci.2018.01.010

    authors: Moner V,Fernández E,Calpena AC,Garcia-Herrera A,Cócera M,López O

    更新日期:2018-05-01 00:00:00

  • Epithelial-mesenchymal transition in the skin.

    abstract::Epithelial-mesenchymal transition (EMT) plays important roles not only in the morphogenesis but also in wound repair, tissue fibrosis and cancer progression. Recently, regulatory mechanism of this process has been elaborately elucidated. EMT can be a new therapeutic target for treating skin ulcer, fibrosing alopecia, ...

    journal_title:Journal of dermatological science

    pub_type: 杂志文章,评审

    doi:10.1016/j.jdermsci.2010.11.015

    authors: Nakamura M,Tokura Y

    更新日期:2011-01-01 00:00:00

  • Genetically engineered mouse models for skin research: taking the next step.

    abstract::Genetically engineered mouse models are invaluable to investigators in nearly all areas of biomedical research. The use of genetically engineered mice has allowed researchers to explore fundamental functions of genes in a mammal that shares substantial similarities with human physiology and pathology. Genetically engi...

    journal_title:Journal of dermatological science

    pub_type: 杂志文章,评审

    doi:10.1016/j.jdermsci.2008.03.012

    authors: Chen J,Roop DR

    更新日期:2008-10-01 00:00:00

  • Two- and three-dimensional observations of human terminal and vellus hair follicles.

    abstract::Extracted human terminal and vellus hair follicles were prepared by EDTA and examined by light and electron microscopes. These samples were morphologically well preserved and enabled us to observe 3-dimensional (3-D) views of the outer surfaces of hair follicles. Interestingly, the bulge areas of terminal and vellus h...

    journal_title:Journal of dermatological science

    pub_type: 杂志文章

    doi:10.1016/0923-1811(94)90030-2

    authors: Narisawa Y,Hashimoto K,Kohda H

    更新日期:1994-07-01 00:00:00

  • Failure to detect paramyxovirus RNA in the skin of connective tissue disease.

    abstract::Etiology of connective tissue disease is unknown. The association of infectious agents has been suspected serologically, ultrastructurally and recently by means of molecular biological techniques. We extracted RNA from lesions of 25 discoid lupus erythematosus, 9 systemic LE, and 3 systemic sclerosis biopsies, and rev...

    journal_title:Journal of dermatological science

    pub_type: 杂志文章

    doi:10.1016/0923-1811(95)00422-x

    authors: Fujiwara H,Fujiwara K,Yotsumoto S,Hashimoto K

    更新日期:1996-01-01 00:00:00

  • PUVA therapy: current concerns in Japan.

    abstract::Photochemotherapy using methoxsalen in combination with long-wave ultraviolet light (PUVA) is an essential modality in the treatment of various skin diseases. Major therapeutic regimens include oral, topical and water-delivery methods. An adequate regimen should be chosen regarding cases of disease, extent of involvem...

    journal_title:Journal of dermatological science

    pub_type: 杂志文章,评审

    doi:10.1016/s0923-1811(98)00065-6

    authors: Danno K

    更新日期:1999-02-01 00:00:00

  • European ancestry and polymorphisms in DNA repair genes modify the risk of melanoma: a case-control study in a high UV index region in Brazil.

    abstract:BACKGROUND:UV radiation is the major environmental factor related to development of cutaneous melanoma. Besides sun exposure and the influence of latitude, some host characteristics such as skin phototype and hair and eye color are also risk factors for melanoma. Polymorphisms in DNA repair genes could be good candidat...

    journal_title:Journal of dermatological science

    pub_type: 杂志文章

    doi:10.1016/j.jdermsci.2011.06.003

    authors: Gonçalves FT,Francisco G,de Souza SP,Luiz OC,Festa-Neto C,Sanches JA,Chammas R,Gattas GJ,Eluf-Neto J

    更新日期:2011-10-01 00:00:00