Striate cortex increases contrast gain of macaque LGN neurons.

Abstract:

:Recurrent projections comprise a universal feature of cerebral organization. Here, we show that the corticofugal projections from the striate cortex (VI) to the lateral geniculate nucleus (LGN) robustly and multiplicatively enhance the responses of parvocellular neurons, stimulated by gratings restricted to the classical receptive field and modulated in luminance, by over two-fold in a contrast-independent manner at all but the lowest contrasts. In the equiluminant plane, wherein stimuli are modulated in chromaticity with luminance held constant, such enhancement is strongly contrast dependent. These projections also robustly enhance the responses of magnocellular neurons but contrast independently only at high contrasts. Thus, these results have broad functional significance at both network and neuronal levels by providing the experimental basis and quantitative constraints for a wide range of models on recurrent projections and the control of contrast gain.

journal_name

Vis Neurosci

journal_title

Visual neuroscience

authors

Przybyszewski AW,Gaska JP,Foote W,Pollen DA

doi

10.1017/s0952523800174012

subject

Has Abstract

pub_date

2000-07-01 00:00:00

pages

485-94

issue

4

eissn

0952-5238

issn

1469-8714

pii

S0952523800174012

journal_volume

17

pub_type

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