Small nodules detected on chest radiography: does size predict calcification?

Abstract:

STUDY OBJECTIVES:To determine whether the likelihood of lung nodule calcification can be predicted from nodule size as measured on a chest radiograph (CXR). DESIGN:Retrospective review of CXRs of patients with lung nodules < or =1 cm in size detected on CT scanning. CT images were used to identify calcifications and to provide spatial localization for readers to visualize nodules on a CXR and to measure their size. A subset of these nodules then was reexamined by different readers who did not view the CT scans SETTING:Two university hospitals (Albuquerque, NM; Dallas, TX) and a US Air Force/Veterans Administration medical center (Albuquerque, NM). PATIENTS:Two hundred thirty-six nodules in 185 patients RESULTS:One half of the nodules (118) seen on CT scans could not be located on CXR, of which 8 (7%) were calcified. The prevalence of calcifications in the other 118 nodules visualized on CXRs was much higher (71 of 118 nodules [60%]; p<0.005). Among the nodules visualized on CXRs, those < 7 mm in diameter (44 of 57 nodules [77%]) were more likely to be calcified than those > or = 7 mm in diameter (27 of 61 nodules [44%]; p<0.005). Radiographs of 42 of the smallest nodules visualized on CXRs by the initial readers later were examined prospectively by different readers who did not have access to the CT images. Thirty of 33 of the calcified nodules (91%) but only 3 of 9 of the noncalcified nodules (33%) were detected (p<0.005). These readers also recorded 40 additional small nodules that were not seen on CT scans, which were considered to be false-positives. CONCLUSIONS:Nodules detected on CXRs that measure <7 mm in size are likely to be calcified or to represent a false-positive finding.

journal_name

Chest

journal_title

Chest

authors

Ketai L,Malby M,Jordan K,Meholic A,Locken J

doi

10.1378/chest.118.3.610

subject

Has Abstract

pub_date

2000-09-01 00:00:00

pages

610-4

issue

3

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(15)36464-3

journal_volume

118

pub_type

杂志文章,多中心研究

相关文献

CHEST文献大全
  • Intrapleural therapy for malignant pleural effusions. A randomized comparison of bleomycin and tetracycline.

    abstract::Between December 1985 and August 1988, there were 115 patients at 13 centers who were entered on a randomized comparison of tetracycline and bleomycin for treatment of malignant pleural effusions. Fifteen patients were not treated, primarily due to rapid progression of systemic cancer. Fifteen patients entered on a hi...

    journal_title:Chest

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1378/chest.100.6.1528

    authors: Ruckdeschel JC,Moores D,Lee JY,Einhorn LH,Mandelbaum I,Koeller J,Weiss GR,Losada M,Keller JH

    更新日期:1991-12-01 00:00:00

  • Diaphragmatic motion studied by m-mode ultrasonography: methods, reproducibility, and normal values.

    abstract:BACKGROUND:Although diaphragmatic motion is readily studied by ultrasonography, the procedure remains poorly codified. The aim of this prospective study was to determine the reference values for diaphragmatic motion as recorded by M-mode ultrasonography. METHODS:Two hundred ten healthy adult subjects (150 men, 60 wome...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.08-1541

    authors: Boussuges A,Gole Y,Blanc P

    更新日期:2009-02-01 00:00:00

  • Administration of anti-TNF antibody improves left ventricular function in septic shock patients. Results of a pilot study.

    abstract::In this pilot study, murine monoclonal anti-TNF antibody (2 mg/kg) was administered to ten patients within 24 h of septic shock which persisted after initial resuscitation with intravenous fluids and adrenergic agents. This treatment resulted in a reduction in heart rate (from 122 +/- 10 to 113 +/- 10 beats per minute...

    journal_title:Chest

    pub_type: 临床试验,杂志文章

    doi:10.1378/chest.101.3.810

    authors: Vincent JL,Bakker J,Marécaux G,Schandene L,Kahn RJ,Dupont E

    更新日期:1992-03-01 00:00:00

  • Increased lung function decline in blue-collar workers exposed to welding fumes.

    abstract:BACKGROUND:There is no consensus at the present time about the effect of welding on lung function decline. This study compared lung function decline between blue-collar workers exposed and not exposed to welding fumes in a French longitudinal cohort of 21,238 subjects aged 37 to 52 years at inclusion. METHODS:Medical ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.11-0647

    authors: Thaon I,Demange V,Herin F,Touranchet A,Paris C

    更新日期:2012-07-01 00:00:00

  • Propranolol-induced urticaria: successful therapy with tolamolol.

    abstract::Urticaria with systemic effects occurred in a patient being treated with propranolol and was reproducible upon rechallenge with the drug; Successful beta-adrenergic blocking therapy was achieved using a new agent, tolamolol, with no evidence of any adverse effects. ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.67.4.496

    authors: Seides SF,Ruskin JN,Damato AN

    更新日期:1975-04-01 00:00:00

  • Percutaneous balloon pericardiotomy for malignant pericardial tamponade.

    abstract::Recurrent pericardial effusion or tamponade can complicate malignant disease. The medical approach with pharmacologic agents has a high recurrence rate. Balloon pericardiotomy (BP) may provide a less invasive alternative to surgery. We performed BP in ten high-risk patients with malignant pericardial tamponade (MPT). ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.108.6.1499

    authors: Galli M,Politi A,Pedretti F,Castiglioni B,Zerboni S

    更新日期:1995-12-01 00:00:00

  • The clinical use of lung MRI in cystic fibrosis: what, now, how?

    abstract::To assess airway and lung parenchymal damage non-invasively in cystic fibrosis (CF), chest MRI has been historically out of the scope of routine clinical imaging due to technical difficulties such as the low proton density and respiratory and cardiac motion. However, technological breakthroughs have recently emerged t...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1016/j.chest.2020.12.008

    authors: Dournes G,Walkup LL,Benlala I,Willmering MM,Macey J,Bui S,Laurent F,Woods JC

    更新日期:2020-12-17 00:00:00

  • Hydrochlorothiazide-induced noncardiogenic pulmonary edema: BAL fluid analysis.

    abstract::Hydrochlorothiazide (HCTZ)-induced pulmonary disease has been described as either an allergic interstitial pneumonitis or a cause of noncardiogenic pulmonary edema. The mechanism of this rare life-threatening side effect is largely unknown. Many patients show peripheral leukopenia and extensive immunologic studies rev...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.10-0944

    authors: Darwish OS,Criley J

    更新日期:2011-01-01 00:00:00

  • Loss of caveolin and heme oxygenase expression in severe pulmonary hypertension.

    abstract::Caveolae are cell plasma membrane microdomains implicated in organizing and concentrating many signaling molecules. In the lung, caveolae are in endothelium, smooth muscle, fibroblasts, and pneumocytes. Caveolin is the main structural protein of caveolae. Caveolin 1 is down-regulated in transformed cells and may be a ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.129.3.696

    authors: Achcar RO,Demura Y,Rai PR,Taraseviciene-Stewart L,Kasper M,Voelkel NF,Cool CD

    更新日期:2006-03-01 00:00:00

  • A 60-year-old woman with cough, dyspnea, and atelectasis 19 years after liver transplant.

    abstract::A 60-year-old black woman presented with nonproductive cough of 1-month duration. She had also experienced rapidly progressive dyspnea for 1 week and one bout of vomiting a day before presentation. Her symptoms had failed to improve with a course of amoxicillin-clavulanate. Her medical history was significant for diab...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.15-0388

    authors: Panchabhai TS,Bandyopadhyay D,Alraiyes AH,Mehta AC,Almeida FA

    更新日期:2015-10-01 00:00:00

  • Transforming growth factor-beta 1 and extracellular matrix-associated fibronectin expression in pulmonary lymphangioleiomyomatosis.

    abstract:STUDY OBJECTIVES:Lymphangioleiomyomatosis (LAM) is a rare disorder of unknown etiology, affecting almost exclusively women of childbearing age, that is associated with the proliferation of spindle cells and cystic changes in the affected lung. The underlying processes that contribute to this disease are poorly understo...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.125.3.1063

    authors: Evans SE,Colby TV,Ryu JH,Limper AH

    更新日期:2004-03-01 00:00:00

  • Rheumatoid nodules in the trachea.

    abstract::We describe the first case of endotracheal rheumatoid nodules in a 45-year-old Chinese man with rheumatoid arthritis. He developed exacerbation of polyarthritis, new subcutaneous nodules and fibrosing alveolitis. At bronchoscopy, four whitish nodules were detected at the tracheal wall, and biopsy showed fibrinoid necr...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.103.1.301

    authors: Ip MS,Wong MP,Wong KL

    更新日期:1993-01-01 00:00:00

  • Inhaled Tranexamic Acid for Hemoptysis Treatment: A Randomized Controlled Trial.

    abstract:BACKGROUND:Tranexamic acid (TA) is an antifibrinolytic drug currently used systemically to control bleeding. To date, there have been no prospective studies of the effectiveness of inhaled TA for the treatment of hemoptysis. OBJECTIVES:The goal of this study was to prospectively assess the effectiveness of TA inhalati...

    journal_title:Chest

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.chest.2018.09.026

    authors: Wand O,Guber E,Guber A,Epstein Shochet G,Israeli-Shani L,Shitrit D

    更新日期:2018-12-01 00:00:00

  • Pulmonary function following the adult respiratory distress syndrome.

    abstract::Fifteen patients (range of ages, 18 to 35 years) who survived an acute episole of the adult respiratory distress syndrome caused by mechanical or thermal injuries, sepsis, and shock were studied during 1 to 30 months after recovery. The patients had had no previous pulmonary diseases, and only two had been smokers. Al...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.74.3.247

    authors: Yahav J,Lieberman P,Molho M

    更新日期:1978-09-01 00:00:00

  • Coronary artery aneurysm. A review of the literature with a report of 11 new cases.

    abstract::In a prospective study, 11 (1.5 percent) of 742 patients had angiographically proven coronary artery aneurysms. The clinical picture was similar to that of patients with severe coronary artery disease. The coronary artery aneurysms were multiple and were associated with extensive coronary atherosclerosis in ten of the...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.69.5.630

    authors: Falsetti HL,Carrol RJ

    更新日期:1976-05-01 00:00:00

  • Outcomes of Nurse Practitioner-Delivered Critical Care: A Prospective Cohort Study.

    abstract:BACKGROUND:Acute care nurse practitioners (ACNPs) are increasingly being employed in ICUs to offset physician shortages, but no data exist about outcomes of critically ill patients continuously cared for by ACNPs. METHODS:Prospective cohort study of all admissions to an adult medical ICU in an academic, tertiary-care ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1016/j.chest.2015.12.015

    authors: Landsperger JS,Semler MW,Wang L,Byrne DW,Wheeler AP

    更新日期:2016-05-01 00:00:00

  • Nutrition in the ICU: an evidence-based approach.

    abstract::Providing artificial nutrition is an important part of caring for critically ill patients. However, because of a paucity of robust data, the practice has been highly variable and often based more on dogma than evidence. A number of studies have been published investigating many different aspects of critical care nutri...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.13-1158

    authors: Desai SV,McClave SA,Rice TW

    更新日期:2014-05-01 00:00:00

  • Measurement of respiratory acoustic signals. Effect of microphone air cavity width, shape, and venting.

    abstract:STUDY OBJECTIVE:We have previously investigated the effects of microphone type and coupler air chamber depth on lung sound characteristics. We now report the results of experiments exploring the effects of air chamber width, shape, and venting on lung sounds. DESIGN:We used a single electret microphone with a variety ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.108.4.1004

    authors: Kraman SS,Wodicka GR,Oh Y,Pasterkamp H

    更新日期:1995-10-01 00:00:00

  • Flexible fiberoptic bronchoscopy. An analysis of proficiency.

    abstract::The purpose of this study was to determine the number of procedures necessary to become proficient in flexible fiberoptic bronchoscopic examination. I performed 99 bronchoscopic procedures during a formal training program under the direct supervision of instructors with varying experience. There were no statistical di...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.77.1.65

    authors: Dull WL

    更新日期:1980-01-01 00:00:00

  • Treatment of diffuse tracheomalacia secondary to relapsing polychondritis with continuous positive airway pressure.

    abstract::Relapsing polychondritis (RP) is a rare disease characterized by recurrent inflammation and destruction of the cartilaginous structures. Tracheobronchial chondritis is a dreaded complication of RP. We wish to report a case of RP of the trachea and bronchi which was treated with nasal continuous positive airway pressur...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.112.6.1701

    authors: Adliff M,Ngato D,Keshavjee S,Brenaman S,Granton JT

    更新日期:1997-12-01 00:00:00

  • Recurrent syncope for over a decade due to idiopathic ventricular fibrillation.

    abstract::A 35-year-old man had a history of recurrent syncope for more than a decade. During a witnessed episode, an ambulatory electrocardiographic recording showed ventricular flutter/fibrillation that lasted for 2 1/2 minutes and terminated spontaneously without adverse neurologic sequelae. No structural heart disease and n...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.106.5.1601

    authors: Masrani K,Cowley C,Bekheit S,el-Sherif N

    更新日期:1994-11-01 00:00:00

  • Coccidioidal pericarditis.

    abstract::A 26-year-old man developed coccidioidomycosis which resulted in myocarditis associated with congestive heart failure. A pericardial effusion developed and progressed to constrictive pericarditis. A pericardiectomy was performed and revealed that the pericarditis was due to Coccidioides immitis. The patient was subseq...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.70.5.670

    authors: Schwartz EL,Waldmann EB,Payne RM,Goldfarb D,Kinard SA

    更新日期:1976-11-01 00:00:00

  • Comparison of the effectiveness of tetracycline and minocycline as pleural sclerosing agents in rabbits.

    abstract::Parenteral tetracycline, one of the most commonly used agents for producing pleurodesis, is no longer available because of stricter regulations governing the manufacturing process. The objective of this project was to determine whether minocycline, a tetracycline derivative, is an effective sclerosant in an experiment...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.106.2.577

    authors: Light RW,Wang NS,Sassoon CS,Gruer SE,Vargas FS

    更新日期:1994-08-01 00:00:00

  • Isolated reduction in single-breath diffusing capacity in the evaluation of exertional dyspnea.

    abstract:UNLABELLED:STUDY SETTINGS AND INTERVENTIONS: Sixty individuals complaining of dyspnea on exertion, but with normal spirometry and lung volumes and normal chest roentgenograms were reviewed for this study. These individuals were selected from a large group of outpatients (552 individuals over a seven-year period) who we...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.101.4.965

    authors: Mohsenifar Z,Collier J,Belman MJ,Koerner SK

    更新日期:1992-04-01 00:00:00

  • Hemianomalous pulmonary venous connection of the left lung surgically corrected.

    abstract::Hemianomalous pulmonary venous connection is a rare congenital abnormality that leads to significant left-to-right shunt and complications related to that. Earlier surgical correction of this disorder was associated with the problem of stenosis at the anastomotic site with the left atrium. We describe the diagnosis of...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.101.6.1718

    authors: Murali VP,Bahuleyan CG,Jayakumar K,Ramanarayan PV,Nair GR

    更新日期:1992-06-01 00:00:00

  • Occult pulmonary abnormalities in asymptomatic asthmatic children.

    abstract::The pulmonary status of 178 asymptomatic asthmatic children with normal time-volume spirograms was further evaluated using flow-volume loops, body plethysmographic studies, and blood gas tensions in arterialized capillary blood. Residual volume (RV) was abnormal in 26%, total lung capacity (TLC) in 33%, RV/TLC% in 41%...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.71.3.361

    authors: Cooper DM,Cutz E,Levison H

    更新日期:1977-03-01 00:00:00

  • Effects of omega-3 polyunsaturated fatty acids on inflammatory markers in COPD.

    abstract:BACKGROUND:COPD, the fifth-leading cause of death worldwide, is characterized by chronic inflammation. However, no available agent can effectively cure this inflammation. A dietary supplement containing omega-3 polyunsaturated fatty acids (PUFAs) has anti-inflammatory effects. In this study, we hypothesized that nutrit...

    journal_title:Chest

    pub_type: 杂志文章,随机对照试验,收录出版

    doi:10.1378/chest.128.6.3817

    authors: Matsuyama W,Mitsuyama H,Watanabe M,Oonakahara K,Higashimoto I,Osame M,Arimura K

    更新日期:2005-12-01 00:00:00

  • Pulmonary hypertension and right heart failure in patients with beta-thalassemia intermedia.

    abstract::We analyzed seven patients with beta-thalassemia intermedia presenting with congestive heart failure secondary to pulmonary hypertension. This condition has been recognized only recently as part of the clinical spectrum of beta-thalassemia. Our group of patients included two men and five women with the clinical pictur...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.107.1.50

    authors: Aessopos A,Stamatelos G,Skoumas V,Vassilopoulos G,Mantzourani M,Loukopoulos D

    更新日期:1995-01-01 00:00:00

  • Effect of a beta 2-agonist (broxaterol) on respiratory muscle strength and endurance in patients with COPD with irreversible airway obstruction.

    abstract::The effect of broxaterol, a new beta 2-agonist, on respiratory muscle endurance and strength was studied in a double-blind, placebo-controlled, randomized crossover clinical trial in 16 patients with chronic obstructive pulmonary disease (COPD) with irreversible airway obstruction (FEV1 = 57.1 percent of predicted). O...

    journal_title:Chest

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1378/chest.101.1.133

    authors: Nava S,Crotti P,Gurrieri G,Fracchia C,Rampulla C

    更新日期:1992-01-01 00:00:00

  • Emergency room intubations--complications and survival.

    abstract::Forty-three consecutive patients requiring endotracheal intubation in an emergency room were studied prospectively to define the complications associated with intubation and the survival of these patients, and to evaluate emergency room policies. The indications for intubation were acute respiratory failure (ARF) in 2...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.75.5.541

    authors: Taryle DA,Chandler JE,Good JT Jr,Potts DE,Sahn SA

    更新日期:1979-05-01 00:00:00