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Activation of murine macrophage-like cells by granulocytin.

Abstract：

:Granulocytin, a C-type lectin from Sarcophaga peregrina (flesh fly), stimulated glucose consumption and cytokine production by the mouse macrophage-like cell line J774.1. When J774.1 cells were pretreated with tunicamycin, their granulocytin-dependent TNF-alpha production was greatly reduced. These results suggest that the stimulus of granulocytin is transmitted to J774.1 cells via the carbohydrate chain of granulocytin receptors located on their surface.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Fujita Y,Homma KJ,Natori S

doi

10.1006/bbrc.2000.3381

subject

Has Abstract

pub_date

2000-09-07 00:00:00

pages

850-3

issue

3

eissn

0006-291X

issn

1090-2104

pii

S0006-291X(00)93381-3

journal_volume

275

pub_type

杂志文章

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