Abstract:
:Caffeoylglucosides, which have a glucose ring as a central linker, were synthesized from methyl D-glucosides, and their anti-HIV-1 activities were tested. Among them, four dicaffeoylglucosides (IC50 = 29.1+/-35.1 microM), 6a, 6b, 9b and 10b, showed HIV-1 integrase inhibitory activity as potent as L-chicoric acid.
journal_name
Bioorg Med Chem Lettjournal_title
Bioorganic & medicinal chemistry lettersauthors
Kim SN,Lee JY,Kim HJ,Shin CG,Park H,Lee YSdoi
10.1016/s0960-894x(00)00355-3subject
Has Abstractpub_date
2000-08-21 00:00:00pages
1879-82issue
16eissn
0960-894Xissn
1464-3405pii
S0960-894X(00)00355-3journal_volume
10pub_type
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