The use of a medical dictionary for regulatory activities terminology (MedDRA) in prescription-event monitoring in Japan (J-PEM).


:The Medical Dictionary for Regulatory Activities Terminology (MedDRA) version 2.1 (V2.1) was released in March 1999 accompanied by the MedDRA/J V2.1J specifically for Japanese users. In prescription-event monitoring in Japan (J-PEM), we have employed the MedDRA/J for data entry, signal generation and event listing. In J-PEM, the lowest level terms (LLTs) in the MedDRA/J are used in data entry because the richness of LLTs is judged to be advantageous. A signal is generated normally at the preferred term (PT) level, but it has been found that various reporters describe the same event using descriptions that are potentially encoded by LLTs under different PTs. In addition, some PTs are considered too specific to generate the proper signal. In the system used in J-PEM, when an LLT is selected as a candidate to encode an event, another LLT under a different PT, if any, is displayed on the computer screen so that it may be coded instead of, or in addition to, the candidate LLT. The five-level structure of the MedDRA is used when listing events but some modification is required to generate a functional event list.


Int J Med Inform


Yokotsuka M,Aoyama M,Kubota K




Has Abstract


2000-07-01 00:00:00














  • Evaluation framework for automatic privacy auditing tools for hospital data breach detections: A case study.

    abstract:OBJECTIVE:We aim to 1) design an evaluation framework to examine the accuracy of automatic privacy auditing tools, 2) apply the evaluation method at a hospital to validate the performance of an auditing tool that uses a machine learning algorithm to automate user access auditing, and 3) recommend further improvements i...

    journal_title:International journal of medical informatics

    pub_type: 杂志文章


    authors: Yesmin T,Carter MW

    更新日期:2020-06-01 00:00:00

  • Automation bias: empirical results assessing influencing factors.

    abstract:OBJECTIVE:To investigate the rate of automation bias - the propensity of people to over rely on automated advice and the factors associated with it. Tested factors were attitudinal - trust and confidence, non-attitudinal - decision support experience and clinical experience, and environmental - task difficulty. The par...

    journal_title:International journal of medical informatics

    pub_type: 杂志文章


    authors: Goddard K,Roudsari A,Wyatt JC

    更新日期:2014-05-01 00:00:00

  • Predicting waiting time to treatment for emergency department patients.

    abstract:BACKGROUND:The current systems of reporting waiting time to patients in public emergency departments (EDs) has largely relied on rolling average or median estimators which have limited accuracy. This study proposes to use machine learning (ML) algorithms that significantly improve waiting time forecasts. METHODS:By im...

    journal_title:International journal of medical informatics

    pub_type: 杂志文章


    authors: Pak A,Gannon B,Staib A

    更新日期:2021-01-01 00:00:00

  • Feasibility of 30-day hospital readmission prediction modeling based on health information exchange data.

    abstract:INTRODUCTION:Unplanned 30-day hospital readmission account for roughly $17 billion in annual Medicare spending. Many factors contribute to unplanned hospital readmissions and multiple models have been developed over the years to predict them. Most researchers have used insurance claims or administrative data to train a...

    journal_title:International journal of medical informatics

    pub_type: 杂志文章,meta分析,多中心研究


    authors: Swain MJ,Kharrazi H

    更新日期:2015-12-01 00:00:00

  • Identifying and prioritizing the tools/techniques of knowledge management based on the Asian Productivity Organization Model (APO) to use in hospitals.

    abstract:INTRODUCTION:Appropriate knowledge, correct information, and relevant data are vital in medical diagnosis and treatment systems. Knowledge Management (KM) through its tools/techniques provides a pertinent framework for decision-making in healthcare systems. The objective of this study was to identify and prioritize the...

    journal_title:International journal of medical informatics

    pub_type: 杂志文章


    authors: Khajouei H,Khajouei R

    更新日期:2017-12-01 00:00:00

  • Investigating the determinants of Chinese adult children's intention to use online health information for their aged parents.

    abstract:BACKGROUND:The increasing number of older people and the dissemination of health information via the Internet have emerged and both are challenging to Chinese society. Available online health information highlights the importance of decision making processes, specially in relation to the elderly who almost have no onli...

    journal_title:International journal of medical informatics

    pub_type: 杂志文章


    authors: Bao Y,Hoque R,Wang S

    更新日期:2017-06-01 00:00:00

  • Parametric estimation of the continuous non-stationary spectrum and its dynamics in surface EMG studies.

    abstract::Frequency spectrum of surface electromyographic signals (SEMGs) exhibit a non-stationary nature even in the case of constant level isometric muscle contractions due to changes related to muscle fatigue processes. These changes can be evaluated by methods for estimation of time-varying (TV) spectrum. The most widely ad...

    journal_title:International journal of medical informatics

    pub_type: 杂志文章


    authors: Korosec D

    更新日期:2000-09-01 00:00:00

  • Clinical information seeking behavior of physicians: A systematic review.

    abstract:INTRODUCTION:Physicians encounter a large number of questions during patient care. Therefore, finding high-quality evidence provides a good opportunity to improve patient care and continue learning. OBJECTIVES:The present study aims to obtain a comprehensive understanding of the physicians' clinical information-seekin...

    journal_title:International journal of medical informatics

    pub_type: 杂志文章


    authors: Daei A,Soleymani MR,Ashrafi-Rizi H,Zargham-Boroujeni A,Kelishadi R

    更新日期:2020-07-01 00:00:00

  • The role of standardized data and terminological systems in computerized clinical decision support systems: literature review and survey.

    abstract:INTRODUCTION:Clinical decision support systems (CDSSs) should be seamlessly integrated with existing clinical information systems to enable automatic provision of advice at the time and place where decisions are made. It has been suggested that a lack of agreed data standards frequently hampers this integration. We per...

    journal_title:International journal of medical informatics

    pub_type: 杂志文章,评审


    authors: Ahmadian L,van Engen-Verheul M,Bakhshi-Raiez F,Peek N,Cornet R,de Keizer NF

    更新日期:2011-02-01 00:00:00

  • Medical informatics at Heidelberg/Heilbronn: status-evaluation-new challenges in a specialised curriculum for medical informatics after thirty years of evolution.

    abstract::After reporting on characteristics, structure and contents of the specialised informatics-based curriculum for medical informatics (MI) at the University of Heidelberg/University of Applied Sciences Heilbronn, the paper describes the development during the last 5 years, and in particular a complementary health care or...

    journal_title:International journal of medical informatics

    pub_type: 杂志文章


    authors: Leven FJ,Knaup P,Schmidt D,Wetter T

    更新日期:2004-03-18 00:00:00

  • The Yale Guideline Recommendation Corpus: a representative sample of the knowledge content of guidelines.

    abstract:OBJECTIVE:To develop and characterize a large, representative sample of guideline recommendations that can be used to better understand how current recommendations are written and to test the adequacy of guideline models. We refer to this sample as the Yale Guideline Recommendation Corpus (YGRC). METHOD:To develop the...

    journal_title:International journal of medical informatics

    pub_type: 杂志文章


    authors: Hussain T,Michel G,Shiffman RN

    更新日期:2009-05-01 00:00:00

  • Speech recognition for the anaesthesia record during crisis scenarios.

    abstract:INTRODUCTION:This article describes the evaluation of a prototype speech-input interface to an anaesthesia patient record, conducted in a full-scale anaesthesia simulator involving six doctor-nurse anaesthetist teams. OBJECTIVE:The aims of the experiment were, first, to assess the potential advantages and disadvantage...

    journal_title:International journal of medical informatics

    pub_type: 杂志文章


    authors: Alapetite A

    更新日期:2008-07-01 00:00:00

  • A deep learning solution to recommend laboratory reduction strategies in ICU.

    abstract:OBJECTIVE:To build a machine-learning model that predicts laboratory test results and provides a promising lab test reduction strategy, using spatial-temporal correlations. MATERIALS AND METHODS:We developed a global prediction model to treat laboratory testing as a series of decisions by considering contextual inform...

    journal_title:International journal of medical informatics

    pub_type: 杂志文章


    authors: Yu L,Li L,Bernstam E,Jiang X

    更新日期:2020-12-01 00:00:00

  • Which barriers affect morbidity registration performance of GP trainees and trainers?

    abstract:BACKGROUND:Diagnosis coding percentages in the specialty training of general practitioners (GPs) are generally high, but not perfect, indicating barriers against coding still exist, possibly influencing the validity of data based on electronic patient records (EPRs). OBJECTIVE:To study the relationship between barrier...

    journal_title:International journal of medical informatics

    pub_type: 杂志文章


    authors: de Jong J,Visser MR,Wieringa-de Waard M

    更新日期:2013-08-01 00:00:00

  • Click yes to consent: Acceptability of incorporating informed consent into an internet-based testing program for sexually transmitted and blood-borne infections.

    abstract:BACKGROUND:Autonomous use of online health care services without interaction with a health care provider challenges existing models for achieving informed consent (IC); current examinations of this issue have focused on commercial direct-to-consumer genetic testing. As IC is integral to publicly funded clinical testing...

    journal_title:International journal of medical informatics

    pub_type: 杂志文章


    authors: Gilbert M,Bonnell A,Farrell J,Haag D,Bondyra M,Unger D,Elliot E

    更新日期:2017-09-01 00:00:00

  • Information quality of a Nursing Information System depends on the nurses: a combined quantitative and qualitative evaluation.

    abstract:PURPOSE:Providing access to patient information is the key factor in nurses' adoption of a Nursing Information System (NIS). In this study the requirements for information quality and the perceived quality of information are investigated. A teaching hospital in the Netherlands has developed a NIS as a module of the Hos...

    journal_title:International journal of medical informatics

    pub_type: 杂志文章


    authors: Michel-Verkerke MB

    更新日期:2012-10-01 00:00:00

  • Physician satisfaction with a critical care clinical information system using a multimethod evaluation of usability.

    abstract:INTRODUCTION:Physician satisfaction with electronic medical records has often been poor. Usability has frequently been identified as a source for decreased satisfaction. While surveys can identify many issues, and are logistically easier to administer, they may miss issues identified using other methods This study soug...

    journal_title:International journal of medical informatics

    pub_type: 杂志文章


    authors: Hudson D,Kushniruk A,Borycki E,Zuege DJ

    更新日期:2018-04-01 00:00:00

  • Measuring mobile patient safety information system success: an empirical study.

    abstract:OBJECTIVE:The Health Risk Reminders and Surveillance (HRRS) system was designed to deliver critical abnormal test results of severely ill patients from Laboratory, Radiology, and Pathology departments to physicians within 5 min using cell phone text messages. This paper explores the success of the HRRS system. METHOD:...

    journal_title:International journal of medical informatics

    pub_type: 杂志文章


    authors: Jen WY,Chao CC

    更新日期:2008-10-01 00:00:00

  • To decay is system: the challenges of keeping a health information system alive.

    abstract::Health information system (HIS) architecture and socio-technical approaches for system deployment have been topics of systematic research for decades. Sustainable operation in gradually changing environments, however, has not yet received sufficient attention. Even HIS that have gone life to the satisfaction of their ...

    journal_title:International journal of medical informatics

    pub_type: 杂志文章


    authors: Wetter T

    更新日期:2007-06-01 00:00:00

  • A wearable approach for intraoperative physiological stress monitoring of multiple cooperative surgeons.

    abstract::It is known that excessive levels of occupational stress affect professionals' technical and non-technical skills and surgeons are no exception. However, very few studies address this problem in neurosurgeons. A system for monitoring cardiovascular strain and autonomic imbalance during intracranial aneurysm procedures...

    journal_title:International journal of medical informatics

    pub_type: 杂志文章


    authors: Pimentel G,Rodrigues S,Silva PA,Vilarinho A,Vaz R,Silva Cunha JP

    更新日期:2019-09-01 00:00:00

  • Electronic consenting for conducting research remotely: A review of current practice and key recommendations for using e-consenting.

    abstract:BACKGROUND:Electronic approaches are becoming more widely used to obtain informed consent for research participation. Electronic consent (e-consent) provides an accessible and versatile approach to the consenting process, which can be enhanced with audio-visual and interactive features to improve participant engagement...

    journal_title:International journal of medical informatics

    pub_type: 杂志文章,评审


    authors: Skelton E,Drey N,Rutherford M,Ayers S,Malamateniou C

    更新日期:2020-11-01 00:00:00

  • Multi-tasking in practice: coordinated activities in the computer supported doctor-patient consultation.

    abstract:UNLABELLED:The paper provides detailed descriptions of general practitioners (GPs') interactions, both with their computers and their patients, with the aim of facilitating the detailed understanding of how GPs use their computers while in consultation with patients. The focus is on the coordinated activities of the do...

    journal_title:International journal of medical informatics

    pub_type: 杂志文章


    authors: Gibson M,Jenkings KN,Wilson R,Purves I

    更新日期:2005-07-01 00:00:00

  • Validating a decision support system for anti-epileptic drug treatment. Part II: adjusting anti-epileptic drug treatment.

    abstract::A model of expertise for monitoring antiepileptic drug treatment was implemented in a decision support system. We validated the advice of the system regarding treatment decisions at first follow-up with 265 paper cases based on patient records. The reference for comparison is based on the opinions of neurologists. We ...

    journal_title:International journal of medical informatics

    pub_type: 杂志文章


    authors: Smeets R,Talmon J,Meinardi H,Hasman A

    更新日期:1999-11-01 00:00:00

  • Evaluating e-consultation implementations based on use and time-line across various specialties.

    abstract:BACKGROUND:Electronic Consultation (e-consults) can provide improved access, enhance patient and provider satisfaction, and reduce beneficiary travel expenses. We explored how e-consults were implemented across three specialty areas, diabetes (Diab), gastroenterology (GI), and neurosurgery (Neuro), at two Veterans Affa...

    journal_title:International journal of medical informatics

    pub_type: 杂志文章


    authors: Parikh PJ,Mowrey C,Gallimore J,Harrell S,Burke B

    更新日期:2017-12-01 00:00:00

  • Electronic health record: design and implementation of a lab test request module.

    abstract:BACKGROUND:The electronic health record (EHR) has become a fundamental tool in health care. The ordering and inclusion of lab tests and results is one of the most frequently requested services by EHR users. We have designed, developed and implemented in Andalusia, an autonomous community in the south of Spain (8.3 mill...

    journal_title:International journal of medical informatics

    pub_type: 杂志文章


    authors: Gascón F,Herrera I,Vázquez C,Jiménez P,Jiménez J,Real C,Pérez F

    更新日期:2013-06-01 00:00:00

  • Semantic similarity-based alignment between clinical archetypes and SNOMED CT: an application to observations.

    abstract:PURPOSE:One of the main challenges of eHealth is semantic interoperability of health systems. But, this will only be possible if the capture, representation and access of patient data is standardized. Clinical data models, such as OpenEHR Archetypes, define data structures that are agreed by experts to ensure the accur...

    journal_title:International journal of medical informatics

    pub_type: 杂志文章


    authors: Meizoso García M,Iglesias Allones JL,Martínez Hernández D,Taboada Iglesias MJ

    更新日期:2012-08-01 00:00:00

  • Use with care: possibilities and constraints offered by computers in nursing clinical education.

    abstract::Funding constraints, demands for improved efficiency, low staff to student ratios and improved computer software (D. Wright, The use of multimedia computers and software in nurse education, Health Inf. 1 (3) (1995) 101-107.) all combine to produce a situation where a dramatic increase in the use of CBE for tertiary nu...

    journal_title:International journal of medical informatics

    pub_type: 杂志文章


    authors: Cheek J,Gillham D,Mills P

    更新日期:1998-06-01 00:00:00

  • SHARE road map for HealthGrids: methodology.

    abstract::The SHARE(1) project ( was asked to identify the key developments needed to achieve wide adoption and deployment of HealthGrids throughout Europe. The project was asked to organise these as milestones on a road map, so that all technical advances, social actions, economic investments and ethica...

    journal_title:International journal of medical informatics

    pub_type: 杂志文章


    authors: Olive M,Rahmouni H,Solomonides T,Breton V,Legré Y,Blanquer I,Hernandez V

    更新日期:2009-04-01 00:00:00

  • Medical support system for continuation of care based on XML web technology.

    abstract::In this paper, the implementation of an Internet-based telematic service for medical support is presented, which was developed and operated in pilot form within the INTRANET HEALTH CLINIC project--a 2-year project supported by the European Commission under the Health Telematics Programme. The aim of the application is...

    journal_title:International journal of medical informatics

    pub_type: 杂志文章


    authors: Stalidis G,Prentza A,Vlachos IN,Maglavera S,Koutsouris D

    更新日期:2001-12-01 00:00:00

  • Evacuation support system for improved medical documentation and information flow in the field.

    abstract:PURPOSE:Documentation of medical treatment and observation of patients during evacuation from the point of injury to definitive treatment is important both for optimizing patient treatment and managing the evacuation process. The current practice in military medical field documentation uses paper forms and voice commun...

    journal_title:International journal of medical informatics

    pub_type: 杂志文章


    authors: Walderhaug S,Meland PH,Mikalsen M,Sagen T,Brevik JI

    更新日期:2008-02-01 00:00:00