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The use of a medical dictionary for regulatory activities terminology (MedDRA) in prescription-event monitoring in Japan (J-PEM).

Abstract：

:The Medical Dictionary for Regulatory Activities Terminology (MedDRA) version 2.1 (V2.1) was released in March 1999 accompanied by the MedDRA/J V2.1J specifically for Japanese users. In prescription-event monitoring in Japan (J-PEM), we have employed the MedDRA/J for data entry, signal generation and event listing. In J-PEM, the lowest level terms (LLTs) in the MedDRA/J are used in data entry because the richness of LLTs is judged to be advantageous. A signal is generated normally at the preferred term (PT) level, but it has been found that various reporters describe the same event using descriptions that are potentially encoded by LLTs under different PTs. In addition, some PTs are considered too specific to generate the proper signal. In the system used in J-PEM, when an LLT is selected as a candidate to encode an event, another LLT under a different PT, if any, is displayed on the computer screen so that it may be coded instead of, or in addition to, the candidate LLT. The five-level structure of the MedDRA is used when listing events but some modification is required to generate a functional event list.

journal_name

Int J Med Inform

journal_title

International journal of medical informatics

authors

Yokotsuka M,Aoyama M,Kubota K

doi

10.1016/s1386-5056(00)00062-9

subject

Has Abstract

pub_date

2000-07-01 00:00:00

pages

139-53

issue

2-3

eissn

1386-5056

issn

1872-8243

pii

S1386-5056(00)00062-9

journal_volume

57

pub_type

杂志文章

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