The Caregiver Activity Survey (CAS): longitudinal validation of an instrument that measures time spent caregiving for individuals with Alzheimer's disease.

abstract：OBJECTIVE:To find a blood biomarker and disease-related peptides in Alzheimer's disease (AD), we comprehensively detected serum peptides. METHODS:Ion intensity of serum peptides from 62 AD patients and 82 control subjects was measured by mass spectrometry. RESULTS:A total of 157 peptides were detected from 30 AD pati...

journal_title：International journal of geriatric psychiatry

authors： Noguchi M,Sato T,Nagai K,Utagawa I,Suzuki I,Arito M,Iizuka N,Suematsu N,Okamoto K,Kato T,Yamaguchi N,Kurokawa MS

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVE:The aims of this study were (a) to determine the frequency of APOE genotypes in dementia, (b) to relate e4 allele frequency to clinical symptomatology of dementia and (c) to relate e4 and assess risk factors for different types of dementia. DESIGN:Prospective clinical study setting older patients with dement...

journal_title：International journal of geriatric psychiatry

authors： Burlinson S,Burns A,Mann D,Pickering-Brown S,Owen F

更新日期：1998-03-01 00:00:00

abstract：OBJECTIVE:Psychosis, like other neuropsychiatric symptoms of dementia, has many features that make predictive modeling of its onset difficult. For example, psychosis onset is associated with both the absolute degree of cognitive impairment and the rate of cognitive decline. Moreover, psychotic symptoms, while more like...

journal_title：International journal of geriatric psychiatry

authors： Seltman HJ,Mitchell S,Sweet RA

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:This study examined changes in cognitive-functional relationships in vascular dementia (VaD) over the course of one year. METHODS:Twenty-four patients with probable VaD were administered the Dementia Rating Scale (DRS). Caregivers completed an informant-based measure of instrumental (IADL) and basic activit...

journal_title：International journal of geriatric psychiatry

authors： Jefferson AL,Cahn-Weiner D,Boyle P,Paul RH,Moser DJ,Gordon N,Cohen RA

更新日期：2006-08-01 00:00:00

abstract：OBJECTIVES:To explore the extent of and factors associated with male residents who change wandering status post nursing home admission. DESIGN:Longitudinal design with secondary data analyses. Admissions over a 4-year period were examined using repeat assessments with the Minimum Data Set (MDS) to formulate a model un...

journal_title：International journal of geriatric psychiatry

authors： King-Kallimanis B,Schonfeld L,Molinari VA,Algase D,Brown LM,Kearns WD,Davis DM,Werner DH,Beattie ER,Nelson AL

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVE:Modifiable risk factors for dementia were recently identified and compiled in a systematic review. The 'Lifestyle for Brain Health' (LIBRA) score, reflecting someone's potential for dementia prevention, was studied in a large longitudinal population-based sample with respect to predicting cognitive change ove...

journal_title：International journal of geriatric psychiatry

authors： Schiepers OJG,Köhler S,Deckers K,Irving K,O'Donnell CA,van den Akker M,Verhey FRJ,Vos SJB,de Vugt ME,van Boxtel MPJ

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:Among dementia professionals in several European countries, it is believed that dementia is under-diagnosed and under-treated to a greater extent among ethnic minorities than in the native population. It is unknown whether this belief holds true. The objective of this study was to compare the prevalence of re...

journal_title：International journal of geriatric psychiatry

authors： Nielsen TR,Vogel A,Phung TK,Gade A,Waldemar G

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVES:Dementia is the most common neurological disease in older adults; headaches, including migraines, are the most common neurological disorder across all ages. The objective of this study was to explore the relationship between migraines and dementia, including Alzheimer's disease (AD) and vascular dementia (Va...

journal_title：International journal of geriatric psychiatry

authors： Morton RE,St John PD,Tyas SL

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVE:This study evaluated the impact of an eight-session training program for aged care staff in managing dementia-related challenging behaviours. Participation in the training program with an additional five-session peer support group was compared with both participation in training only and a wait-list control c...

journal_title：International journal of geriatric psychiatry

authors： Davison TE,McCabe MP,Visser S,Hudgson C,Buchanan G,George K

更新日期：2007-09-01 00:00:00

abstract：OBJECTIVES:Older adults with psychiatric disorders have a substantially lower life expectancy than age-matched controls. Knowledge of risk factors may lead to targeting treatment and interventions to reduce this gap in life expectancy. In this study, we investigated whether frailty independently predicts mortality in o...

journal_title：International journal of geriatric psychiatry

authors： Benraad CEM,Haaksma ML,Karlietis MHJ,Oude Voshaar RC,Spijker J,Melis RJF,Olde Rikkert MGM

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:This study aimed to investigate the association of alcohol use disorder (AUD) with four candidate genes in older Korean men: aldehyde dehydrogenase 2 (ALDH2, 1/2), brain-derived neurotrophic factor (BDNF, val66met), serotonin transporter gene linked polymorphic region (5-HTTLPR, s/l), and methylenetetrahydro...

journal_title：International journal of geriatric psychiatry

authors： Shin S,Stewart R,Ferri CP,Kim JM,Shin IS,Kim SW,Yang SJ,Yoon JS

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVE:The objective of this study is to determine whether resilience is associated with depressive symptoms in geriatric populations. METHOD:A systematic review and meta-analysis were performed (up to March 2015) following the Preferred Reporting Items for Systematic Reviews and Meta-analysis recommendations on th...

journal_title：International journal of geriatric psychiatry

authors： Wermelinger Ávila MP,Lucchetti AL,Lucchetti G

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVES:The pattern of neural damage in dementia with Lewy Bodies (DLB) led us to hypothesize that patients with DLB would be particularly impaired on parallel ('pop-out') search tasks, relative to serial search tasks, and that this would serve to distinguish DLB from other forms of neurodegenerative disease, partic...

journal_title：International journal of geriatric psychiatry

authors： Cormack F,Gray A,Ballard C,Tovée MJ

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:Computer-administered assessment of cognitive function is being increasingly incorporated in clinical trials; however, its performance in these settings has not been systematically evaluated. DESIGN:The Seniors Health and Activity Research Program pilot trial (N = 73) developed a computer-based tool for ass...

journal_title：International journal of geriatric psychiatry

authors： Espeland MA,Katula JA,Rushing J,Kramer AF,Jennings JM,Sink KM,Nadkarni NK,Reid KF,Castro CM,Church T,Kerwin DR,Williamson JD,Marottoli RA,Rushing S,Marsiske M,Rapp SR,LIFE Study Group.

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to use group reminiscence therapy (GRT) as a nursing intervention to evaluate the post-test, 3-month and 6-month effects on depressive symptoms for institutionalised male veterans after a 4-week intervention. METHODS:A quasi-experimental design and purposive sampling was conduct...

journal_title：International journal of geriatric psychiatry

authors： Chueh KH,Chang TY

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Vascular dementia (VaD) is associated with impairments in cognitive, motor, and functional domains. Patients with VaD display diverse cognitive and motor deficits, however, and relationships between these impairments and independent living abilities remain unclear. OBJECTIVES:The purpose of the present stud...

journal_title：International journal of geriatric psychiatry

authors： Boyle PA,Cohen RA,Paul R,Moser D,Gordon N

更新日期：2002-02-01 00:00:00

abstract：OBJECTIVE:The study objective is to evaluate the use of qEEG data for the cross-sectional differentiation of mild cognitive impairment (MCI) from mild Alzheimer's disease (AD) and in the longitudinal prediction of cognitive decline in MCI. METHODS:Eighty-eight subjects with MCI and 42 subjects with mild probable AD we...

journal_title：International journal of geriatric psychiatry

authors： Luckhaus C,Grass-Kapanke B,Blaeser I,Ihl R,Supprian T,Winterer G,Zielasek J,Brinkmeyer J

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:Mild cognitive impairment (MCI) is a clinical concept that categorizes subjects who are in an intermediate cognitive state between normal aging and dementia. The aim of this study is to characterize behavior in MCI compared with Alzheimer's disease (AD) and healthy older patients. DESIGN:A cross-sectional a...

journal_title：International journal of geriatric psychiatry

authors： Van der Mussele S,Le Bastard N,Vermeiren Y,Saerens J,Somers N,Mariën P,Goeman J,De Deyn PP,Engelborghs S

更新日期：2013-03-01 00:00:00

abstract：:Dementia in community settings is often diagnosed by computerized algorithms. This study examines the extent to which independent diagnosticians agreed among themselves in diagnosing dementia, severity and type when presented with data obtained during a population-based incidence study of cognitive decline and dementi...

journal_title：International journal of geriatric psychiatry

authors： Kay DW,Dewey ME,McKeith IG,O'Cuill M,McCracken C,Fairbairn AF,Harrison R,Illing JC,Hrisos S

更新日期：1998-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the association between regular physical activity and the risk of incident dementia in older Japanese adults. METHODS:This was a retrospective cohort study performed in Okayama City, Japan. Overall, 51 477 older Japanese adults were followed from 2008 to 2014. A health checkup questionnaire was u...

journal_title：International journal of geriatric psychiatry

authors： Liu Y,Mitsuhashi T,Yamakawa M,Sasai M,Tsuda T,Doi H,Hamada J

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:It is unclear whether patients with late onset and patients with early onset present with different subtypes of depression. The aim of the study was to compare the prevalence of subtypes of ICD-10 single depressive episodes for patients with late onset (age >65 years) and patient with early onset (age < or = ...

journal_title：International journal of geriatric psychiatry

authors： Kessing LV

更新日期：2006-12-01 00:00:00

abstract：AIMS:The aim of the present study was to examine the factors influencing intentions to seek a cognitive status evaluation among first-degree relatives of persons with Alzheimer's disease. METHODS:Phone interviews were conducted with 93 first-degree relatives of persons with Alzheimer's disease, recruited from a large ...

journal_title：International journal of geriatric psychiatry

authors： Werner P,Heinik J

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:Little evidence is available about how quality of life (QoL) changes as dementia progresses. OBJECTIVES:We explored QoL trajectories over a 20-month period and examined what predicted change in QoL. METHOD:Fifty-one individuals with a diagnosis of Alzheimer's, vascular or mixed dementia (people with dement...

journal_title：International journal of geriatric psychiatry

authors： Clare L,Woods RT,Nelis SM,Martyr A,Marková IS,Roth I,Whitaker CJ,Morris RG

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVE:To elucidate the extent to which elderly people with cognitive impairment are able to answer questions about their quality of life.Design and setting308 elderly residents were interviewed within 2 weeks of admission to one of 30 residential or nursing homes in north-west England. MEASURES:The Mini-Mental Sta...

journal_title：International journal of geriatric psychiatry

authors： Mozley CG,Huxley P,Sutcliffe C,Bagley H,Burns A,Challis D,Cordingley L

更新日期：1999-09-01 00:00:00

abstract：OBJECTIVES:Physical symptoms are known to be associated with late life depression both cross-sectionally and over time. We attempted to determine if self-reported shortness of breath (SoB) is associated with depressive symptoms at long-term (3-year) follow-up in a community sample of older (65+) adults. METHODS:A samp...

journal_title：International journal of geriatric psychiatry

authors： Blazer DG,Hybels CF

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVES:The objectives of this study are to explore the feasibility of a multicomponent intervention programme and to evaluate its impacts on behavioural and psychological symptoms of dementia (BPSD) and psychological health of caregivers. METHODS:Fifty-six community-dwelling people with dementia (PWD) and knee ost...

journal_title：International journal of geriatric psychiatry

authors： Law W,Kwok TCY

更新日期：2019-12-01 00:00:00

abstract：OBJECTIVE:To assess the cost effectiveness of cholinesterase inhibitor (ChEI) treatment in patients with Alzheimer's disease (AD) and Dementia with Lewy bodies (DLB). METHOD:We used 4-month open label follow-up data from routine memory clinic patients. There were 852 patients with AD and 112 with DLB. We applied three...

journal_title：International journal of geriatric psychiatry

authors： Gustavsson A,Van Der Putt R,Jönsson L,McShane R

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVE:The purpose of this study is to assess whether atypical antipsychotic drug (AAD) use is associated with increased risk of falling among older (≥65 years) nursing home (NH) residents. METHODS:We conducted a nested case-control study using Resident Assessment Instrument Minimum Data Set 2.0 (RAI-MDS(©)) for NH...

journal_title：International journal of geriatric psychiatry

authors： Bozat-Emre S,Doupe M,Kozyrskyj AL,Grymonpre R,Mahmud SM

更新日期：2015-08-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to assess the short-term tolerability of two titration schedules of sublingual asenapine in older patients with psychosis, not associated with organic brain disease, and to compare asenapine pharmacokinetics in older patients versus younger adults with schizophrenia. METHODS:Patien...

journal_title：International journal of geriatric psychiatry

authors： Dubovsky SL,Frobose C,Phiri P,de Greef R,Panagides J

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Morbidity among elderly people has an important influence on their psychological well-being. Evaluation of the morbidity profile and its determinants, which have implications for management of medical problems of elderly people, are scarce in developing countries. Even the physicians' detection rate of menta...

journal_title：International journal of geriatric psychiatry

authors： Prakash O,Gupta LN,Singh VB,Singhal AK,Verma KK

更新日期：2007-11-01 00:00:00