Inference on a collapsed margin in disease mapping.


:This paper describes a method for estimating the risk from a disease over a set of contiguous geographical regions, when data on a potentially important covariate, such as race, are not available. Conditions under which the extra margin can be recovered are suggested. An application to prostate cancer mortality among the non-white population in the counties of the U.S.A. is discussed.


Stat Med


Statistics in medicine


Byers S,Besag J




Has Abstract


2000-09-15 00:00:00














  • Rank-based principal stratum sensitivity analyses.

    abstract::We describe rank-based approaches to assess principal stratification treatment effects in studies where the outcome of interest is only well-defined in a subgroup selected after randomization. Our methods are sensitivity analyses, in that estimands are identified by fixing a parameter and then we investigate the sensi...

    journal_title:Statistics in medicine

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    authors: Lu X,Mehrotra DV,Shepherd BE

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  • Analysis of antiretroviral immunotherapy trials with potentially non-normal and incomplete longitudinal data.

    abstract::For many HIV-infected patients, use of antiretroviral therapy (ART) results in a sustained suppression of plasma viral load to undetectable levels. However, due to lack of antigenic stimulation, this may also result in a gradual loss of cell-mediated immune (CMI) responses that help control HIV infection. In concept, ...

    journal_title:Statistics in medicine

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    authors: Mogg R,Mehrotra DV

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  • Constructing binomial confidence intervals with near nominal coverage by adding a single imaginary failure or success.

    abstract::In this paper we present a simple method for constructing (1- alpha)100 per cent confidence intervals for binomial proportions with near nominal coverage for all underlying proportion parameters on the unit interval. This new method uses, with a slight modification, the standard normal approximation technique taught i...

    journal_title:Statistics in medicine

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    authors: Borkowf CB

    更新日期:2006-11-15 00:00:00

  • Extending the c-statistic to nominal polytomous outcomes: the Polytomous Discrimination Index.

    abstract::Diagnostic problems in medicine are sometimes polytomous, meaning that the outcome has more than two distinct categories. For example, ovarian tumors can be benign, borderline, primary invasive, or metastatic. Extending the main measure of binary discrimination, the c-statistic or area under the ROC curve, to nominal ...

    journal_title:Statistics in medicine

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    authors: Van Calster B,Van Belle V,Vergouwe Y,Timmerman D,Van Huffel S,Steyerberg EW

    更新日期:2012-10-15 00:00:00

  • Considerations for analysis of time-to-event outcomes measured with error: Bias and correction with SIMEX.

    abstract::For time-to-event outcomes, a rich literature exists on the bias introduced by covariate measurement error in regression models, such as the Cox model, and methods of analysis to address this bias. By comparison, less attention has been given to understanding the impact or addressing errors in the failure time outcome...

    journal_title:Statistics in medicine

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    authors: Oh EJ,Shepherd BE,Lumley T,Shaw PA

    更新日期:2018-04-15 00:00:00

  • Statistical interim monitoring of the Cardiac Arrhythmia Suppression Trial.

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    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验


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    journal_title:Statistics in medicine

    pub_type: 杂志文章


    authors: Van Houwelingen JC,Le Cessie S

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  • A survey of models for repeated ordered categorical response data.

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    journal_title:Statistics in medicine

    pub_type: 杂志文章


    authors: Agresti A

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  • Sample size to test for interaction between a specific exposure and a second risk factor in a pair-matched case-control study.

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    authors: Qiu P,Moeschberger ML,Cooke GE,Goldschmidt-Clermont PJ

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  • Two-stage residual inclusion for survival data and competing risks-An instrumental variable approach with application to SEER-Medicare linked data.

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    journal_title:Statistics in medicine

    pub_type: 杂志文章


    authors: Ying A,Xu R,Murphy J

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  • Hierarchical multiple informants models: examining food environment contributions to the childhood obesity epidemic.

    abstract::Methods for multiple informants help to estimate the marginal effect of each multiple source predictor and formally compare the strength of their association with an outcome. We extend multiple informant methods to the case of hierarchical data structures to account for within cluster correlation. We apply the propose...

    journal_title:Statistics in medicine

    pub_type: 杂志文章


    authors: Baek J,Sánchez BN,Sanchez-Vaznaugh EV

    更新日期:2014-02-20 00:00:00

  • Estimating net transition probabilities from cross-sectional data with application to risk factors in chronic disease modeling.

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    authors: Kassteele Jv,Hoogenveen RT,Engelfriet PM,Baal PH,Boshuizen HC

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  • Statistical comparison of two handwashing protocols.

    abstract::This paper describes statistical procedures for use in an experiment that compares two handwashing protocols. The evaluation of a handwashing protocol entails collection of the wash effluent. Colony counts for the effluent reflect the number of flora removed by the wash protocol. The analysis aims to formulate and est...

    journal_title:Statistics in medicine

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Le CT

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    journal_title:Statistics in medicine

    pub_type: 杂志文章


    authors: Sjölander A

    更新日期:2009-02-15 00:00:00

  • Robustness of the two independent samples t-test when applied to ordinal scaled data.

    abstract::One may encounter the application of the two independent samples t-test to ordinal scaled data (for example, data that assume only the values 0, 1, 2, 3) from small samples. This situation clearly violates the underlying normality assumption for the t-test and one cannot appeal to large sample theory for validity. In ...

    journal_title:Statistics in medicine

    pub_type: 杂志文章


    authors: Heeren T,D'Agostino R

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    journal_title:Statistics in medicine

    pub_type: 杂志文章


    authors: Hu Z,Follmann D

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    abstract:BACKGROUND:It has been recommended that onset of antidepressant action be assessed using survival analyses with assessments taken at least twice per week. However, such an assessment schedule is problematic to implement. The present study assessed the feasibility of comparing onset of action between treatments using a ...

    journal_title:Statistics in medicine

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    authors: Mallinckrodt CH,Detke MJ,Kaiser CJ,Watkin JG,Molenberghs G,Carroll RJ

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    journal_title:Statistics in medicine

    pub_type: 杂志文章


    authors: le Cessie S,de Vries EG,Buijs C,Post WJ

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  • Conditional power and predictive power based on right censored data with supplementary auxiliary information.

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    journal_title:Statistics in medicine

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    authors: Sun L,Wan Y

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    journal_title:Statistics in medicine

    pub_type: 杂志文章


    authors: Suissa S,Blais L

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    abstract::In recent years, follow-on biological products (biosimilars) have received much attention from both the biotechnology industry and the regulatory agencies, especially after the passage of the 2010 healthcare reform bill. Unlike the traditional small-molecule drug products, the development of biological products is not...

    journal_title:Statistics in medicine

    pub_type: 杂志文章


    authors: Yang J,Zhang N,Chow SC,Chi E

    更新日期:2013-02-10 00:00:00

  • Cancer immunotherapy trial design with cure rate and delayed treatment effect.

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    journal_title:Statistics in medicine

    pub_type: 杂志文章


    authors: Wei J,Wu J

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    journal_title:Statistics in medicine

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    authors: Barcella W,Iorio MD,Baio G,Malone-Lee J

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    journal_title:Statistics in medicine

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    authors: Liu A,Wu C,Schisterman EF

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    journal_title:Statistics in medicine

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    journal_title:Statistics in medicine

    pub_type: 杂志文章


    authors: Deng D

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    abstract::Disease incidence or disease mortality rates for small areas are often displayed on maps. Maps of raw rates, disease counts divided by the total population at risk, have been criticized as unreliable due to non-constant variance associated with heterogeneity in base population size. This has led to the use of model-ba...

    journal_title:Statistics in medicine

    pub_type: 杂志文章


    authors: Stern HS,Cressie N

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    journal_title:Statistics in medicine

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    authors: Lipsitz SR,Buoncristiani JF

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    journal_title:Statistics in medicine

    pub_type: 杂志文章


    authors: Zhou XH,Katz BP,Holleman E,Melfi CA,Dittus R

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    abstract::Diseases can be interconnected. In the recent years, there has been a surge of multidisease studies. Among them, HDN (human disease network) analysis takes a system perspective, examines the interconnections among diseases along with their individual properties, and has demonstrated great potential. Most of the existi...

    journal_title:Statistics in medicine

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    authors: Ma C,Li Y,Shia B,Ma S

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