Xotx5b, a new member of the Otx gene family, may be involved in anterior and eye development in Xenopus laevis.

abstract：:Members of the cysteine-rich protein (CRP) define a subclass of LIM-only proteins implicated mainly in muscle differentiation. Until now, very little is known concerning the expression of CRP encoding genes during vertebrate development. We describe here the isolation of a trout (Oncorhynchus mykiss) gene encoding a c...

journal_title：Mechanisms of development

authors： Delalande JM,Rescan PY

更新日期：1998-08-01 00:00:00

abstract：:Lobopodium is a hyaline cytoplasmic protrusion which rotates circumferencially around a cell. This movement is called circus movement, which is seen in dissociated cells of amphibian embryos. Relative abundance of the lobopodia-forming cells changes temporally and spatially within Xenopus embryos, reflecting stage-dep...

journal_title：Mechanisms of development

authors： Minoura I,Nakamura H,Tashiro K,Shiokawa K

更新日期：1995-01-01 00:00:00

abstract：:Imitation Switch (ISWI) is a member of the SWI2/SNF2 superfamily of ATP-dependent chromatin remodelers, which regulate transcription and maintain chromatin structure by mobilizing nucleosomes using the energy of ATP. Four distinct ISWI complexes have been identified in Xenopus oocytes. The developmental role of Xenopu...

journal_title：Mechanisms of development

authors： Dirscherl SS,Henry JJ,Krebs JE

更新日期：2005-11-01 00:00:00

abstract：:Following tissue damage the immune response, including inflammation, has been considered an inevitable condition to build the host defense against invading pathogens. The recruitment of innate immune leukocytes to injured tissue is observed in both vertebrates and invertebrates. However, it is still not conclusive whe...

journal_title：Mechanisms of development

authors： Katsuyama T,Paro R

更新日期：2013-02-01 00:00:00

abstract：:The Polycomb group genes in Drosophila are involved in the stable and inheritable repression of gene expression. The Polycomb group proteins probably operate as multimeric complexes that bind to chromatin. To investigate molecular mechanisms of stable repression of gene activity in vertebrates we have begun to study X...

journal_title：Mechanisms of development

authors： Reijnen MJ,Hamer KM,den Blaauwen JL,Lambrechts C,Schoneveld I,van Driel R,Otte AP

更新日期：1995-09-01 00:00:00

abstract：:Epimorphic regeneration is a process allowing the animal to regain its lost structure which depends on the resident pluripotent stem cells as well as de-differentiation of existing cells to form multi-potent stem cells. Many studies have been done to understand the appendage regeneration mechanism. The animal model us...

journal_title：Mechanisms of development

authors： Murawala H,Ranadive I,Patel S,Desai I,Balakrishnan S

更新日期：2018-04-01 00:00:00

abstract：:We present a complete staging table of normal development for the lungless salamander, Hemidactylium scutatum (Caudata: Plethodontidae). Terrestrial egg clutches from naturally ovipositing females were collected and maintained at 15 °C in the laboratory. Observations, photographs, and time-lapse movies of embryos were...

journal_title：Mechanisms of development

authors： Hurney CA,Babcock SK,Shook DR,Pelletier TM,Turner SD,Maturo J,Cogbill S,Snow MC,Kinch K

更新日期：2015-05-01 00:00:00

abstract：:The runt gene plays an important role in the genetic hierarchy that generates the segmented body pattern during the early stages of Drosophila embryogenesis. We studied mRNA expression in mutant embryos in order to investigate the regulation of runt transcription during these stages. We used sensitive whole-mount in s...

journal_title：Mechanisms of development

authors： Klingler M,Gergen JP

更新日期：1993-09-01 00:00:00

abstract：:We have identified a Drosophila gene encoding a putative receptor tyrosine kinase by screening a genomic DNA library with a DNA probe for a Drosophila homolog of fibroblast growth factor receptors. The newly isolated gene codes for a transmembrane protein most similar in sequence to a mammalian proto-oncogene ret; thu...

journal_title：Mechanisms of development

authors： Sugaya R,Ishimaru S,Hosoya T,Saigo K,Emori Y

更新日期：1994-02-01 00:00:00

abstract：:The segmentation of vertebrate embryos depends on a complex genetic network that generates highly dynamic gene expression. Many of the elements of the network have been identified, but their interaction and their influence on segmentation remain poorly understood. A few mathematical models have been proposed to explai...

journal_title：Mechanisms of development

authors： Cinquin O

更新日期：2007-08-01 00:00:00

abstract：:The embryonic fins and the tip of adult fins of teleost fish are supported by rows of straight, unmineralized fibrils called actinotrichia. The proximal ends of the actinotrichia are bundled and the mineralized bones called lepidotrichia are made along them. Since malformation in actinotrichia causes wavy fin bones, t...

journal_title：Mechanisms of development

authors： Kuroda J,Iwane AH,Kondo S

更新日期：2018-10-01 00:00:00

abstract：:We present the first time/space analysis using in situ hybridization for PTTG and prc1 genes during development of the mouse telencephalon. During the stages E11.5-E13.5 PTTG and prc1 are expressed in most tissues of the embryo. Within the telencephalon, PTTG and prc1 are found exclusively inside of the ventricular zo...

journal_title：Mechanisms of development

authors： Tarabykin V,Britanova O,Fradkov A,Voss A,Katz LS,Lukyanov S,Gruss P

更新日期：2000-04-01 00:00:00

abstract：:Although the molecular mechanisms directing anteroposterior patterning of the Drosophila embryo (long-germband mode) are well understood, how these mechanisms were evolved from an ancestral mode of insect embryogenesis remains largely unknown. In order to gain insight into mechanisms of evolution in insect embryogenes...

journal_title：Mechanisms of development

authors： Shinmyo Y,Mito T,Matsushita T,Sarashina I,Miyawaki K,Ohuchi H,Noji S

更新日期：2005-02-01 00:00:00

abstract：:The dual nature of pancreatic tissue permits both endocrine and exocrine functions. Enzymatic secretions by the exocrine pancreas help digestive processes while the pancreatic hormones regulate glucose homeostasis and energy metabolism. Pancreas organogenesis is defined by a conserved array of signaling pathways that ...

journal_title：Mechanisms of development

authors： Dumasia NP,Pethe PS

更新日期：2020-12-01 00:00:00

abstract：:The cloning of a Pax6 orthologue from the sepiolid squid Euprymna scolopes and its developmental expression pattern are described. The data are consistent with the presence of a single gene encoding a protein with highly conserved DNA-binding paired and homeodomains. A detailed expression analysis by in situ hybridiza...

journal_title：Mechanisms of development

authors： Hartmann B,Lee PN,Kang YY,Tomarev S,de Couet HG,Callaerts P

更新日期：2003-02-01 00:00:00

abstract：:In Drosophila melanogaster, the patterning of dorsal appendages on the eggshell is strictly controlled by EGFR signaling. However, the number of dorsal appendages is remarkably diverse among Drosophila species. For example, D. melanogaster and D. virilis have two and four dorsal appendages, respectively. Here we show ...

journal_title：Mechanisms of development

authors： Nakamura Y,Matsuno K

更新日期：2003-08-01 00:00:00

abstract：:Polycomb group (PcG) proteins regulate and maintain expression pattern of genes set early during development. Although originally isolated as regulators of homeotic genes, PcG members play a key role in epigenetic mechanisms that maintain the expression state of a large number of genes. All members of the two polycomb...

journal_title：Mechanisms of development

authors： Sowpati DT,Ramamoorthy S,Mishra RK

更新日期：2015-11-01 00:00:00

abstract：:Adhesion differences are the main driver of cell sorting and related processes such as boundary formation or tissue positioning. In the early amphibian embryo, graded variations in cadherin density and localized expression of adhesion-modulating factors are associated with regional differences in adhesive properties i...

journal_title：Mechanisms of development

authors： Winklbauer R,Parent SE

更新日期：2017-04-01 00:00:00

abstract：:To investigate the origin and nature of the signals responsible for specification of the dermatomal lineage, excised axial organs in 2-day-old chick embryos were replaced by grafts of the dorsal neural tube, or the ventral neural tube plus the notochord, or aggregates of cells engineered to produce Sonic hedgehog (Shh...

journal_title：Mechanisms of development

authors： Olivera-Martinez I,Thélu J,Teillet MA,Dhouailly D

更新日期：2001-02-01 00:00:00

abstract：:In the process of cloning murine proteins capable of binding to a regulatory module of the Ncam promoter, we isolated a novel homeobox gene, Barx1, the first vertebrate member of the structural subclass defined by Drosophila BarH1. Here we report its sequence, chromosomal localisation and embryonic expression pattern....

journal_title：Mechanisms of development

authors： Tissier-Seta JP,Mucchielli ML,Mark M,Mattei MG,Goridis C,Brunet JF

更新日期：1995-05-01 00:00:00

abstract：:All body pigment cells in vertebrates are derived from the neural crest. In fish the neural crest can generate up to six different types of pigment cells, as well as various non-pigmented derivatives. In mouse and zebrafish, extensive collections of pigmentation mutants have enabled dissection of many aspects of pigme...

journal_title：Mechanisms of development

authors： Kelsh RN,Inoue C,Momoi A,Kondoh H,Furutani-Seiki M,Ozato K,Wakamatsu Y

更新日期：2004-07-01 00:00:00

abstract：:The homeotic or Hox genes encode a network of conserved transcription factors which provide axial positional information and control segment morphology in development and evolution. During embryonic brain development of Drosophila, the Hox gene labial (lab) is essential for tritocerebral neuromere specification; lab l...

journal_title：Mechanisms of development

authors： Meier S,Sprecher SG,Reichert H,Hirth F

更新日期：2006-01-01 00:00:00

abstract：:In chick embryos, naso-temporal polarity of the retina becomes established before Hamburger-Hamilton stage 10. To examine the plasticity of the early eye anlage, double-temporal eyes were made using stage 10-11 (E1.5) chick embryos and stage 8-9 quail embryos. In vivo and in vitro experiments revealed that these doubl...

journal_title：Mechanisms of development

authors： Mueller BK,Dütting D,Haase A,Feucht A,Macchi P

更新日期：1998-06-01 00:00:00

abstract：:The neural crest (NC) is one of the most fascinating structures during embryonic development. Unique to vertebrate embryos, these cells give rise to important components of the craniofacial skeleton, such as the jaws and skull, as well as melanocytes and ganglia of the peripheral nervous system. Worldwide, several gro...

journal_title：Mechanisms of development

authors： Pescador GS,Trentin AG,Garcez RC

更新日期：2018-10-01 00:00:00

abstract：:During vertebrate eye development, the expression of the homeobox gene Six6 is restricted to the neural retina and is initiated later than Rx and Pax6 in the presumptive retina field. We show here that overexpression of mouse Six6 in Xenopus embryos can induce transformation of competent tissue of the anterior neural ...

journal_title：Mechanisms of development

authors： Bernier G,Panitz F,Zhou X,Hollemann T,Gruss P,Pieler T

更新日期：2000-05-01 00:00:00

abstract：:Cell fate specification during inner ear development is dependent upon regional gene expression within the otic vesicle. One of the earliest cell fate determination steps in this system is the specification of neural precursors, and regulators of this process include the Atonal-related basic helix-loop-helix genes, Ng...

journal_title：Mechanisms of development

authors： Friedman RA,Makmura L,Biesiada E,Wang X,Keithley EM

更新日期：2005-05-01 00:00:00

abstract：:The diencephalon is the caudal part of the developing forebrain that gives rise to the epithalamus, thalamus, hypothalamus and retina. The mature diencephalon is functionally and anatomically parceled into well-defined nuclei. In an effort to understand how this region of the brain develops we examined the expression ...

journal_title：Mechanisms of development

authors： Lim Y,Golden JA

更新日期：2002-07-01 00:00:00

abstract：:Five chick homeodomain proteins (CHOXs), CHOX-1.7, -1.1, -1.4, -4.2 and -2.6, had different transcription-regulating activities in a chick cultured cell line, LMH. In particular, CHOX-1.7 highly activated transcription when NP6 was used as the target site whereas CHOX-1.4 did not. This was mainly due to differences in...

journal_title：Mechanisms of development

authors： Sasaki H,Yamamoto M,Kuroiwa A

更新日期：1992-03-01 00:00:00

abstract：:Six/sine oculis (Six/so) class genes, with representatives in vertebrates and invertebrates, include members with key developmental roles in the anterior part of the central nervous system (CNS) and eye. Having characterized the role of the first planarian gene of the Six/so family in eye development, we attempted to ...

journal_title：Mechanisms of development

authors： Pineda D,Saló E

更新日期：2002-12-01 00:00:00

abstract：:The tramtrack (ttk) gene of Drosophila encodes 69-kDa and 88-kDa proteins through alternative splicing of the primary ttk transcript. The two proteins share a common amino-terminal sequence, but contain different carboxy-terminal portions, each of which has a distinct zinc finger domain with a unique DNA binding speci...

journal_title：Mechanisms of development

authors： Read D,Levine M,Manley JL

更新日期：1992-09-01 00:00:00