Intracranial malignant meningioma with abdominal metastases associated with hypoglycemic shock: a case report.

Abstract:

:A thirty-year-old male with an intracranial malignant meningioma, first diagnosed 9 years ago, with three recurrences was admitted with a hypoglycemic shock. The blood glucose level was 17 mg/dl, requiring treatment with high doses of intravenous and oral dextrose for improvement. A large metastatic tumor in the liver was noted. All hormones and peptides influencing blood glucose levels were in their normal levels. Chemo-embolization and injection of anti-cancer drugs was employed in the management of the metastatic tumor. Positron emission tomography was performed to measure the glucose metabolism of the abdominal tumor and it indicated that glucose consumption within the tumor was much elevated than the surrounding abdominal organs. Hypoglycemia secondary to primary hepatoma or islet-cell cancer has been frequently described, but a complication of metastatic meningioma is an exceedingly rare event. Elevated glucose consumption within the tumor might be addressed as one of the reasons for hypoglycemia, not due to the elevated serum levels of insulin or IGF, but due to the closely related blood glucose level.

journal_name

J Neurooncol

authors

Yoshida D,Sugisaki Y,Tamaki T,Saitoh N,Node Y,Shimura T,Teramoto A

doi

10.1023/a:1006460827300

subject

Has Abstract

pub_date

2000-03-01 00:00:00

pages

51-8

issue

1

eissn

0167-594X

issn

1573-7373

journal_volume

47

pub_type

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