Abstract：
:A 56-year-old woman presented with the typical findings of cicatricial pemphigoid: vesicular lesions of the mucous membranes and skin. Ocular involvement included symblepharon and dryness. A regimen of 80 mg of oral trimcinolone per day healed the lesions of the skin and mucous membrane. The patient received three injections of 0.5 ml of triamcinolone acetonide into the area of the symblepharon without apparent effect on the ocular disease. Direct immunofluorescent microscopy of the patient's conjunctiva revealed fluorescence of the basement membrane when incubated with fluorescein labeled anti-IgG. The finding of immunologlobulin fixed to be basement membrane in cicatricial pepmhigoid indicates some type of immune mechanism, and would seem to place this entity in the spectrum of the pemphigus-pemphigoid group.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Herron BEdoi
10.1016/0002-9394(75)90081-1subject
Has Abstractpub_date
1975-02-01 00:00:00pages
271-8issue
2eissn
0002-9394issn
1879-1891pii
0002-9394(75)90081-1journal_volume
79pub_type
杂志文章abstract：PURPOSE:Low docosahexaenoic acid (DHA) in X-linked retinitis pigmentosa (XLRP) may influence retinal function. The goals of this study were to elevate blood DHA levels and determine the effect on the rate of disease progression. DESIGN:In a 4-year prospective randomized clinical trial, male patients with XLRP (mean ag...
journal_title：American journal of ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/j.ajo.2003.10.045
更新日期：2004-04-01 00:00:00
abstract：:Using the Cochet-Bonnet esthesiometer, we evaluated the corneal sensation of 11 patients with unilateral Adie's tonic pupil. We eliminated six other patients with bilateral Adie's pupil or disease that lowered corneal sensation. An observed unfamiliar with each patient's condition tested 12 clock hour positions in the...
journal_title：American journal of ophthalmology
pub_type： 临床试验,杂志文章
doi：10.1016/0002-9394(77)90440-8
更新日期：1977-10-01 00:00:00
abstract：PURPOSE:To quantify ocular higher-order aberrations (HOAs) in eyes with supernormal vision, that is, natural uncorrected visual acuity (UCVA) > or = 20/15, to analyze the correlation between ocular HOAs and age in these eyes, and to investigate the correlation of HOAs between right and left eyes. DESIGN:Observational ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2004.08.035
更新日期：2005-02-01 00:00:00
abstract：:A 6-year-old boy with a visual acuity of 6/30 (20/100) in each eye had a diffuse corneal epithelial disruption that was most severe in the interpalpebral area. Corneal anesthesia was demonstrated with the Cochet-Bonnet aesthesiometer. Artificial tears, lubricant ointments, and taping of the eyelids were unsuccessful i...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)77729-3
更新日期：1978-03-01 00:00:00
abstract：PURPOSE:To report a case of bilateral periopticoscleral hemorrhages associated with traumatic child abuse. METHODS:Postmortem gross examination and histopathologic studies of both eyes and the optic nerves of a 6-month-old infant who died from subdural hematoma. RESULTS:Gross examination and histopathologic step sect...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(98)00392-4
更新日期：1999-04-01 00:00:00
abstract：PURPOSE:To perform a reference case, cost-utility analysis of epiretinal membrane (ERM) surgery using current literature on outcomes and complications. DESIGN:Computer-based, value-based medicine analysis. METHODS:Decision analyses were performed under two scenarios: ERM surgery in better-seeing eye and ERM surgery i...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2007.12.037
更新日期：2008-05-01 00:00:00
abstract：PURPOSE:Immune checkpoint inhibitors (ICI) targeting the programmed cell death protein 1 (PD-1), or its ligand PD-L1, are the mainstay of metastatic cancer treatment. Patients receiving these treatments may develop immune-related adverse events (irAEs). This study aimed to estimate the prevalence and describe the clini...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2019.02.012
更新日期：2019-06-01 00:00:00
abstract：:We evaluated whether the rate of occurrence of glaucomatous disk damage in eyes with an optic disk hemorrhage differed from the rate of occurrence in control eyes. We compared 24 patients with a disk hemorrhage to 24 control patients, who had been matched for diagnosis, disk appearance, and visual fields. Cup volume a...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)74272-2
更新日期：1987-04-15 00:00:00
abstract：PURPOSE:To screen a population with primary open-angle glaucoma for mutations in the gene that encodes the trabecular meshwork inducible glucocorticoid response protein (TIGR), also known as myocilin (MYOC). METHODS:Ophthalmologic information was collected for study subjects with primary open-angle glaucoma and their ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(00)00536-5
更新日期：2000-08-01 00:00:00
abstract：PURPOSE:To assess socioeconomic disparity in global burden of cataract, by using disability-adjusted life years (DALYs). DESIGN:International, comparative burden-of-disease study. METHODS:Published data on national age-standardized DALY rates caused by cataract and human development index (HDI) between 1990 and 2013 ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2017.04.008
更新日期：2017-08-01 00:00:00
abstract：PURPOSE:To evaluate changes in contrast sensitivity after surgery for macula-on rhegmatogenous retinal detachment (RRD). DESIGN:Prospective, interventional, consecutive, case-control study. METHODS:This study included 84 eyes of 84 patients with unilateral macula-on RRD undergoing primary scleral buckling or vitrecto...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2013.05.017
更新日期：2013-10-01 00:00:00
abstract：PURPOSE:We sought to assess the correlation of corneal endothelial cell (CEC) density to alterations of collagen composition of Descemet membrane (DM) in advanced Fuchs endothelial corneal dystrophy (FECD) and to image such changes by slit-lamp biomicroscopy in vivo. DESIGN:Prospective, observational consecutive case ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2020.09.030
更新日期：2020-09-21 00:00:00
abstract：PURPOSE:To evaluate for which range of refractive error the optic disk size depends on, or is independent of, the refractive error. DESIGN:Clinical observational study. METHODS:The study included 1999 eyes of 1011 subjects with a mean refractive error of -0.97 +/- 2.72 diopters (range, -24.25 to +9.4 diopters). Optic...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2004.07.047
更新日期：2005-02-01 00:00:00
abstract：PURPOSE:To report the features of idiopathic intracranial hypertension in prepubertal children, with emphasis on presentation, treatment, and outcome. METHODS:We retrospectively reviewed the charts of all patients 11 years and younger diagnosed with idiopathic intracranial hypertension at two university-affiliated med...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(98)00386-9
更新日期：1999-02-01 00:00:00
abstract：PURPOSE:To delineate the clinical features, course, complications, and associated systemic diseases in patients with HLA-B27-associated uveitis. METHODS:We reviewed the records of 148 patients with HLA-B27-associated uveitis from two large uveitis practices. RESULTS:There were 127 (86%) white and 21 (14%) nonwhite pa...
journal_title：American journal of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/s0002-9394(14)70533-1
更新日期：1996-01-01 00:00:00
abstract：PURPOSE:To compare three phacoemulsification machines for measurement accuracy and postocclusion surge (POS) in human cadaver eyes. DESIGN:In vitro comparisons of machine accuracy and POS. METHODS:Tip vacuum and flow were compared with machine indicated vacuum and flow. All machines were placed in two human cadaver e...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2008.01.024
更新日期：2008-06-01 00:00:00
abstract：PURPOSE:To assess quantitatively the cumulative effect of hyperglycemia on lens transparency in patients with juvenile type 1 diabetes mellitus. METHODS:Subjects were 30 patients (30 eyes) with type 1 diabetes mellitus who had well-documented records on the duration of diabetes mellitus and condition of glycemic contr...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(00)00804-7
更新日期：2001-03-01 00:00:00
abstract：PURPOSE:To report the successful use of topical cysteamine formulated from the oral preparation in the treatment of severe photophobia from corneal crystal deposition in cystinosis. DESIGN:Interventional case report. METHODS:Retrospective chart review. RESULTS:An 8-year-old boy with nephropathic cystinosis was exper...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2004.05.005
更新日期：2004-10-01 00:00:00
abstract：PURPOSE:To present the first detailed assessment of the clinical features of CL-induced subconjunctival hemorrhage and associated risk factors. DESIGN:Cross-sectional and case-control study of age-matched randomized groups. METHODS:A total of 45 CL wearers with subconjunctival hemorrhage aged 18 to 45 years (CL-Hemor...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2010.05.028
更新日期：2010-11-01 00:00:00
abstract：PURPOSE:To determine the necessity for the heightened level of monitoring for cataract development in patients taking quetiapine (Seroquel, AstraZeneca Pharmaceuticals, Wilmington, Delaware) dictated by the Physicians' Desk Reference. Also, to explore the possibility of cataractogenesis because of quetiapine therapy. ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2004.05.038
更新日期：2004-11-01 00:00:00
abstract：:Recurrent erosion of the cornea has been well documented in patients with nontraumatic anterior membrane dystrophies of various types. We examined five patients who, in addition to an erosion, developed stromal keratitis. Three of these patients were subjected to a complete microbiologic workup, but the lesions were a...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)75006-8
更新日期：1985-07-15 00:00:00
abstract：PURPOSE:To describe a modified technique of haptic externalization during repositioning of dislocated posterior chamber lens implants, which facilitates placement of scleral fixation sutures around the haptic for implant stabilization. METHODS:We describe a technique of repositioning a dislocated posterior chamber imp...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(00)00650-4
更新日期：2001-01-01 00:00:00
abstract：PURPOSE:To measure the change of peripapillary retinal vessel density (VD) in eyes with a history of acute primary angle-closure glaucoma (PACG). DESIGN:Case-control study. METHODS:Twenty-one consecutive Chinese patients with history of unilateral acute PACG were enrolled. Eyes with acute PACG constituted the case gr...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2017.07.024
更新日期：2017-10-01 00:00:00
abstract：PURPOSE:To compare polymerase chain reaction (PCR) results to presumptive clinical diagnosis in patients with vitritis. DESIGN:Retrospective review of PCR laboratory records from vitreous samples. METHODS:Fifty consecutive laboratory records of vitreous samples sent for PCR testing were reviewed. Three reviewers with...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2005.10.011
更新日期：2006-03-01 00:00:00
abstract：PURPOSE:To compare the effects of extracapsular cataract extraction with posterior chamber intraocular lens (ECCE/PC-IOL) vs intracapsular cataract extraction with aphakic glasses (ICCE-AG) on everyday visual functioning and quality of life. METHODS:In a nonmasked randomized controlled clinical trial, 3,400 bilateral ...
journal_title：American journal of ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0002-9394(99)80231-1
更新日期：1998-01-01 00:00:00
abstract：PURPOSE:To evaluate the ocular surface inflammatory response to the presence of preservatives in nonselective beta-blocker eyedrops. DESIGN:Prospective, crossover, single-masked, randomized clinical study. METHODS:study population: Twenty primary open-angle glaucoma or ocular hypertensive patients were divided in two...
journal_title：American journal of ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/j.ajo.2004.08.028
更新日期：2005-01-01 00:00:00
abstract：PURPOSE:To evaluate the correlation between tear film lipid layer thickness and other objective measurements such as tear film break-up time (TBUT), upper and lower meibomian gland losses, and Schirmer 1 test in patients with obstructive meibomian gland dysfunction (MGD) and normal controls. DESIGN:Cross-sectional stu...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2013.01.008
更新日期：2013-06-01 00:00:00
abstract：PURPOSE:To evaluate the contribution of maximal removal of the deep lateral wall of the orbit to exophthalmos reduction in Graves' orbitopathy and its influence on the onset of consecutive diplopia. DESIGN:Case-control study. METHODS:The medical records of two cohorts of patients affected by Graves' orbitopathy with ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2005.04.023
更新日期：2005-10-01 00:00:00
abstract：PURPOSE:To determine whether an association exists between dry eye disease (DED) and statin use and/or dyslipidemia. DESIGN:Retrospective, case-control study. METHODS:Setting: University of North Carolina (UNC)-affiliated healthcare facilities. STUDY POPULATION:72,931 patients seen at UNC ophthalmology clinics over ...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2020.05.007
更新日期：2020-10-01 00:00:00
abstract：PURPOSE:To report the efficacy of an aggressive systematic regimen for the treatment of acute nonarteritic central retinal artery occlusion (CRAO). METHODS:Eleven patients who had unilateral CRAO with symptoms of fewer than 48 hours' duration were treated with an aggressive stepwise systematic regimen until retinal ci...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(99)00359-1
更新日期：1999-12-01 00:00:00
