Abstract:
:Tenotomy is a commonly encountered clinical entity, whether traumatic or iatrogenic. This article reviews the response of skeletal muscle to tenotomy. The changes are subdivided into molecular, architectural, and functional categories. Architectural disruption of the muscle includes myofiber disorganization, central core necrosis, Z-line streaming, fibrosis of fibers and Golgi tendon organs, changes in sarcomere number, and alterations in the number of membrane particles. Molecular changes include transient changes in myosin heavy chain composition and expression of neural cell adhesion molecule (NCAM). Functionally, tenotomized muscle produces decreased maximum tetanic and twitch tension. Alterations in normal skeletal muscle structure and function are clinically applicable to the understanding of pathological states that follow tendon rupture and iatrogenic tenotomy.
journal_name
Muscle Nervejournal_title
Muscle & nerveauthors
Jamali AA,Afshar P,Abrams RA,Lieber RLdoi
10.1002/(sici)1097-4598(200006)23:6<851::aid-mus3>subject
Has Abstractpub_date
2000-06-01 00:00:00pages
851-62issue
6eissn
0148-639Xissn
1097-4598pii
10.1002/(SICI)1097-4598(200006)23:6<851::AID-MUS3>journal_volume
23pub_type
杂志文章,评审相关文献
MUSCLE & NERVE文献大全abstract:INTRODUCTION:Muscle fiber denervation increases with age, yet studies at the tissue level are sparse due to the challenging nature of establishing the relative role of regeneration and denervation. METHODS:Muscle biopsies were obtained from the vastus lateralis of 70 healthy men (aged 72 ± 6 years; range, 65-94). Mess...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.26638
更新日期:2019-10-01 00:00:00
abstract::We have developed an algorithm, called multi-motor unit action potential analysis (MMA), to aid quantification in routine needle EMG examination. In only 5-8 min, it was possible to extract, analyze, and validate 20 motor unit action potentials (MUAPs). In the biceps muscle of normal subjects, the MUAP measurements ar...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880181012
更新日期:1995-10-01 00:00:00
abstract::A prospective study was done on 222 consecutive new patients referred to our pediatric muscle clinic to assess the diagnostic value of ultrasound imaging. Ultrasound scans were interpreted without knowledge of clinical presentation or results of other tests. Muscular dystrophy produced a brightly speckled pattern of i...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880110110
更新日期:1988-01-01 00:00:00
abstract:INTRODUCTION:Two previously reported Norwegian patients with painful muscle cramps and giant myotonic discharges were genotyped and compared with those of members of 21 families harboring the same mutation. METHODS:Using primers specific for SCN4A and CLCN1, the DNA of the Norwegian family members was amplified and bi...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.24672
更新日期:2015-10-01 00:00:00
abstract:INTRODUCTION:Valosin-containing protein (VCP) variants that affect muscle, bone, and the nervous system are termed multisystem proteinopathy. VCP myopathy is manifested as limb-girdle weakness, distal weakness and scapuloperoneal weakness. METHODS:We reviewed clinical, genetic, and muscle biopsy data from 6 members of...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.26389
更新日期:2019-03-01 00:00:00
abstract::We report a patient who experienced progressive diplopia and distal weakness of the upper limbs. Magnetic resonance imaging of the brain showed extensive white matter lesions and analysis of cerebrospinal fluid revealed acute human T-lymphotropic virus type I (HTLV-I) infection. Myasthenia gravis (MG) was evidenced by...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.20694
更新日期:2007-04-01 00:00:00
abstract:INTRODUCTION:Nemaline myopathy is a rare disorder characterized by skeletal muscle weakness of varying severity and onset, with the presence of nemaline rods on muscle biopsy. Congenital nemaline body myopathy due to mutations in TNNT1 has hitherto only been described as a result of a single founder mutation in patient...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.24885
更新日期:2016-04-01 00:00:00
abstract::The purpose of this study was to determine whether initial muscle length influenced the extent of isometric force deficit following 20 in vitro lengthening contractions of the soleus muscle from Fischer 344 rats. Force deficit was evaluated following one of five protocols: (1) lengthening contractions from optimal mus...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.10112
更新日期:2002-06-01 00:00:00
abstract:INTRODUCTION:RASopathies are a group of genetic conditions due to alterations of the Ras/MAPK pathway. Neurocutaneous findings are hallmark features of the RASopathies, but musculoskeletal abnormalities are also frequent. The objective was to evaluate handgrip strength in the RASopathies. METHODS:Individuals with RASo...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.23324
更新日期:2012-09-01 00:00:00
abstract::Changes in contractile rate of force development (RFD), measured within a short time interval from contraction initiation, were measured after a period of strength training that led to increases in muscle fascicle length but no measurable change in neuromuscular activity. The relationship between training-induced shif...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.21259
更新日期:2009-04-01 00:00:00
abstract::The frequency of a recently described point mutation of the ciliary neurotrophic factor (CNTF) gene was investigated in a population of 154 German patients with motor neuron disease (MND). Twenty-two percent of the patients were heterozygous, 2% homozygous for the CNTF mutation. Since the gene defect is per se not lin...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/(sici)1097-4598(199802)21:2<236::aid-mus12
更新日期:1998-02-01 00:00:00
abstract::Voluntary and stimulation single-fiber electromyography were performed in the extensor digitorum communis muscle of 15 myasthenic patients. The increase in mean and individual mean consecutive difference as well as the proportion of blocking in the volitional activation were greater than in the stimulation method. The...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/(sici)1097-4598(199808)21:8<1081::aid-mus1
更新日期:1998-08-01 00:00:00
abstract::Dystrophic changes of Schwann cells and demyelination occurred in rats with chronic nerve edema induced by feeding a galactose-rich diet for two years. The mechanism for edema is the sorbitol pathway which generates osmotically active polyols from galactose or glucose. The blood-nerve barrier impedes diffusion of macr...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880060309
更新日期:1983-03-01 00:00:00
abstract::Muscle weakness in myasthenia gravis is due to autoantibody-induced loss of functional acetylcholine receptors (AChR). About 15% of myasthenia gravis patients, however, do not have detectable anti-AChR antibodies. To investigate the effect of their plasma immunoglobulins on neuromuscular transmission, mice were inject...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880171208
更新日期:1994-12-01 00:00:00
abstract:INTRODUCTION:We investigated the viscoelastic stress relaxation response before and after a 10-week hamstrings static stretch program. METHODS:The maximal range of motion (ROMmax ) and maximal torque (Torquemax ) were assessed before and after a 10-week stretching program. Six 30-s static stretches at a predetermined ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.24593
更新日期:2015-05-01 00:00:00
abstract:BACKGROUND:In adult males, cross-sectional area (CSA) for type II muscle fibers is generally larger than for type I fibers. In this cross-sectional study the aim was to compare sex-related CSAs of various muscle fiber types during childhood-to-adulthood transition. METHODS:Percutaneous biopsy samples were obtained fro...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.27151
更新日期:2020-12-21 00:00:00
abstract::Phospholipid methylation is thought to modulate such vital cellular processes as calcium transport, receptor function, and membrane microviscosity. As these processes are fundamental to the function of muscle cells and are thought to be altered in disease states, we have characterized several features of phospholipid ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880080513
更新日期:1985-06-01 00:00:00
abstract::There were 31 Duchenne patients placed on overnight mouth intermittent positive pressure ventilation for severe respiratory insufficiency at the average age of 19.9 years. Most patients had vital capacities less than 200 cc at their last evaluations. Of these, 23 patients are alive at the average age of 27 years and l...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880100212
更新日期:1987-02-01 00:00:00
abstract::This study attempts to gain a better understanding of the primary cause of doxorubicin myotoxicity to aid in the development of a protocol to increase its effectiveness in treating muscle spasm diseases. The time course of acute injury to the orbicularis oculi muscle after injection of doxorubicin into the eyelids of ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880160708
更新日期:1993-07-01 00:00:00
abstract:INTRODUCTION:Information related to the long-term follow-up of neuropathy in patients with familial amyloid polyneuropathy after liver transplantation is still scarce. METHODS:We describe the neuropathic features of 3 patients with the transthyretin Val30Met mutation. Each patient underwent liver transplantation at an...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.23480
更新日期:2012-12-01 00:00:00
abstract::A method for quantifying shape variability, the jiggle, or motor unit potentials (MUPs) recorded with conventional EMG electrodes is presented. Amplitude variability at each point of time of the MUP was analyzed. Two new parameters are proposed: the normalized value of the consecutive amplitude differences (CAD), and ...
journal_title:Muscle & nerve
pub_type: 临床试验,杂志文章
doi:10.1002/mus.880171003
更新日期:1994-10-01 00:00:00
abstract::This study was designed to compare electromyogram (EMG) and acoustic myogram (AMG) recordings of biceps brachii muscles in patients with spastic cerebral palsy (CP). The maximal voluntary contraction (MVC) in the CP group was approximately one half of that of the normal group even after being normalized by the muscle ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/(SICI)1097-4598(199610)19:10<1252::AID-MUS
更新日期:1996-10-01 00:00:00
abstract:INTRODUCTION:We performed a retrospective analysis of the clinical, pathological, and electrophysiological features of 21 cases of Asymptomatic vasculitic neuropathy (AsVN). METHODS:Among 270 patients with biopsy-proven vasculitic neuropathy, we identified 21 (7.8%) who had asymptomatic neuropathy. RESULTS:Of the 21 ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.24494
更新日期:2015-07-01 00:00:00
abstract:INTRODUCTION:We determined whether instrumenting timed functional tasks with wireless inertial motion sensors were responsive to facioscapulohumeral muscular dystrophy (FSHD) progression and movement pattern changes. METHODS:Ten individuals who were clinically affected with genetically confirmed FSHD, mean age 54 year...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.26681
更新日期:2019-11-01 00:00:00
abstract::During postnatal development of extensor digitorum longus (EDL) muscle, sodium withdrawal contractures were observed during the first 6 days after birth, and not after this time. In regenerating EDL muscles, zero-Na contractures were demonstrated: (1) 7 days after bupivacaine injection, but not 14 or 90 days after thi...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/(sici)1097-4598(199811)21:11<1530::aid-mus
更新日期:1998-11-01 00:00:00
abstract::Neuroinflammation is a characteristic of pathologically affected tissue in several neurodegenerative disorders. These changes can be observed in the brainstem and spinal cord of amyotrophic lateral sclerosis (ALS) cases and in mouse models of the disease. They include an accumulation of large numbers of activated micr...
journal_title:Muscle & nerve
pub_type: 杂志文章,评审
doi:10.1002/mus.10191
更新日期:2002-10-01 00:00:00
abstract:INTRODUCTION:In this study we noninvasively evaluated skeletal muscle mitochondrial capacity, muscle-specific endurance, and energy/fatigue feelings in persons with Friedreich ataxia (FRDA) and able-bodied controls (AB). METHODS:Forearm mitochondrial capacity was measured in FRDA (n = 16) and AB (n = 10) study partici...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.25524
更新日期:2017-10-01 00:00:00
abstract::Guillain-Barré syndrome (GBS) is an inflammatory polyradiculoneuropathy associated with numerous viral infections. Recently, there have been many case reports describing the association between coronavirus disease-2019 (COVID-19) and GBS, but much remains unknown about the strength of the association and the features ...
journal_title:Muscle & nerve
pub_type: 杂志文章,评审
doi:10.1002/mus.27024
更新日期:2020-10-01 00:00:00
abstract::Evidence suggests that sensory loss may occur in a proportion of patients affected by poliomyelitis. We hypothesize that sensory problems may be a lasting sequela in some polio survivors. Sensory pathways in polio survivors were evaluated clinically and electrophysiologically using sensory evoked potentials (SEPs). Pa...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.21093
更新日期:2008-10-01 00:00:00
abstract::Mutations of the valosin-containing protein gene (VCP) are responsible for autosomal-dominant hereditary inclusion-body myopathy associated with frontotemporal dementia and Paget's disease of bone. We identified the p.R155C missense mutation in the VCP gene segregating in an Italian family with three affected siblings...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.20890
更新日期:2008-01-01 00:00:00