Abstract:
:In sub-Saharan Africa, tick infestation and tick-borne infections together with tsetse-transmitted trypanosomosis arguably constitute the main parasitological disease complex constraining livestock production. Resistance to tick attack and tick-borne micro-organisms (TBMs) varies among different breeds of cattle. The magnitude of losses due to these parasites is related to an extent to the degree of breed resistance. Generally, zebu (Bos indicus) cattle possess a higher resistance to ticks and TBMs than European (Bos taurus) cattle. The host's immune system would appear to be the single most important factor that regulates this resistance. This paper reports on the main effector immune mechanisms governing resistance against ticks and TBMs. The cellular immune response appears more effective and stable than humoral immunity in modulating resistance to ticks and TBMs. Similarities between the immune mechanisms employed by trypanotolerant N'Dama (B. taurus) cattle, when infected with trypanosomes, and those elicited by tick bites and TBMs seem to exist, particularly at the skin level in the early phases of parasitic invasion. Moreover, there is evidence that in the N'Dama breed, resistance against ticks per se also has a genetic basis. Therefore, the N'Dama appears to be a unique breed in that it exhibits resistance to several parasitic diseases and/or infections, including helminths, when compared to other cattle breeds in West Africa. It is concluded that the multi-parasite resistant traits of the N'Dama breed should be exploited in those areas where trypanosomosis, ticks and tick-borne diseases constrain animal production. This should be of benefit for low-input farming systems where the use of chemicals for prophylaxis and therapy is limited by their relatively high cost. Additionally, the potential contribution of multiple disease resistant N'Dama cattle should be considered in crossbreeding programmes with exotic dairy breeds for increasing milk production in West Africa.
journal_name
Acta Tropjournal_title
Acta tropicaauthors
Mattioli RC,Pandey VS,Murray M,Fitzpatrick JLdoi
10.1016/s0001-706x(00)00063-2subject
Has Abstractpub_date
2000-05-31 00:00:00pages
263-77issue
3eissn
0001-706Xissn
1873-6254pii
S0001706X00000632journal_volume
75pub_type
杂志文章,评审相关文献
ACTA TROPICA文献大全abstract::The aim of this study was to assess, whether polymerase chain reaction (PCR) allows sensitive screening of treatment failure suspicions in areas, where drug resistance against African animal trypanosomosis (AAT) appears to be a problem. PCR was used to detect trypanosome infections prior to, 14 and 28 days after contr...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2004.04.003
更新日期:2004-09-01 00:00:00
abstract::Benflumetol, a novel antimalarial compound belonging to the fluorenes (2,3-benzindenes), has high blood schizontocidal activity, in vitro and in vivo, against mammalian plasmodia, including chloroquine-resistant Plasmodium falciparum. Due to its molecular structure benflumetol occurs in the dextrorotatory and the laev...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/s0001-706x(97)00141-1
更新日期:1998-06-15 00:00:00
abstract::A randomized controlled trial was carried out in Assab under the auspices of the National Organization for the Control of Malaria and other Vectorborne Diseases of Ethiopia to assess the effectiveness of an indigenous cyprinodontid fish, Aphanius dispar, in controlling mosquito larvae, including the local malaria vect...
journal_title:Acta tropica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0001-706x(92)90032-s
更新日期:1992-12-01 00:00:00
abstract::Species of Haemoproteus (Haemosporida, Haemoproteidae) are widespread and often prevalent blood parasites of birds all over the word. They are particularly diverse in tropical countries. Due to limited knowledge of life cycles, these pathogens usually have been considered relatively benign and were neglected in veteri...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2019.105051
更新日期:2019-09-01 00:00:00
abstract::Swine influenza is responsible for one of the most prevalent disease affecting the swine industry worldwide. Epidemiological surveys rarely focus on remote areas, because traditional farming systems characterized by locally consumed production and low pig densities are considered as having little influence on the emer...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2011.11.012
更新日期:2012-04-01 00:00:00
abstract::The present work examines the thermal preference of adult Rhodnius prolixus along a temperature gradient. The mean preferred temperature differed slightly between sexes: 25.0 degrees C for males versus 25.4 degrees C for females. This preference was not constant, but varied daily by about 0.2 degrees C for both sexes,...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2003.11.006
更新日期:2004-03-01 00:00:00
abstract::Studies elucidate conflicting results about the relationships between ABO blood groups and Plasmodium infection outcomes in humans. This study examined association between ABO blood group and Plasmodium falciparum (P. falciparum) malaria related outcomes among 1065 malaria suspected febrile patients who attended Dore ...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2012.04.012
更新日期:2012-09-01 00:00:00
abstract::Macrophages infected with amastigotes of Leishmania mexicana mexicana as compared to normal macrophages show decreased migration both randomly and through a 5 microns pore in response to a known chemotaxin, an increased ability to pinocytose and an increased bactericidal ability. Unless very heavily parasitized their ...
journal_title:Acta tropica
pub_type: 杂志文章
doi:
更新日期:1983-03-01 00:00:00
abstract::As Guinea worm eradication programmes have got under way in endemic countries over the last decade, there has been a shift towards more participatory methods. The approach to surveillance has changed from periodic cross-sectional surveys to monthly village-based reporting of cases by a volunteer village health worker....
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/0001-706x(95)00106-o
更新日期:1996-04-01 00:00:00
abstract::Bashagard is an important malaria endemic area in south of Iran. An epidemiological and entomological survey was performed during 2002-2010. The aim of study was to determine malaria situation, species composition of anopheline mosquitoes and susceptibility status of main vectors to insecticides/larvicides. A total of...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2011.04.017
更新日期:2012-02-01 00:00:00
abstract::By using the criteria that define emerging infectious diseases (EIDs) of humans, we can identify a similar group of EIDs in wildlife. In the current review we highlight an important series of wildlife EIDs: amphibian chytridiomycosis; diseases of marine invertebrates and vertebrates and two recently-emerged viral zoon...
journal_title:Acta tropica
pub_type: 杂志文章,评审
doi:10.1016/s0001-706x(00)00179-0
更新日期:2001-02-23 00:00:00
abstract::Pangonius theodori a new horse fly species (Diptera: Tabanidae: Pangoniinae) from northern Israel and southern Lebanon is described. The zoogeography, habitat preference and taxonomic position within the genus of the new species is discussed in detail. ...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2012.11.009
更新日期:2013-03-01 00:00:00
abstract::We have developed a molecular method using PCR-direct sequencing to identify the infective 3rd juvenile stage of Angiostrongylus cantonensis, a nematode parasite of rodents that can accidentally infect humans and cause eosinophilic meningitis. We demonstrate that the 5' end of the small subunit (SSU) ribosomal (r) RNA...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2007.10.007
更新日期:2008-02-01 00:00:00
abstract::Leishmania infantum is a protozoan that causes visceral leishmaniasis, a potentially deadly neglected tropical disease. The gold standard for diagnosis has traditionally been detection of amastigotes in bone marrow or spleen aspirates, but this is an invasive procedure that carries the risk of serious complications. N...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2017.12.011
更新日期:2018-02-01 00:00:00
abstract::The objective of this study was to determine the presence of Trypanosoma cruzi in blood samples of mothers with chronic Chagas disease and their newborn by conventional PCR targeted to minicircle kinetoplastidic DNA (kDNA), and to determine the lineages in mother/newborn pairs of the congenital cases by hybridization ...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2012.08.001
更新日期:2012-12-01 00:00:00
abstract::A cross-sectional sero-epidemiological study was conducted to determine the prevalence of dengue in Trinidad. Two commercial rapid test kits, PanBio Dengue Duo IgM and IgG Rapid Strip Test and the Bio-Check Plus Dengue G/M Cassette Test (Brittney) were used. The immunosorbent assay (ELISA) (FOCUS Technologies, Califor...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2006.11.009
更新日期:2007-02-01 00:00:00
abstract::Microorganisms harbored by Chilean autochthonous ticks have been scarcely studied and current knowledge is restricted to three species of hard ticks only. The current study aimed to assess the presence of Anaplasmataceae, Borrelia and Hepatozoon agents in ticks collected directly from the environment, on reptiles, bir...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2019.02.002
更新日期:2019-04-01 00:00:00
abstract::Schistosomiasis is one of the most common parasitic diseases in tropical and subtropical areas, including Brazil. A national control programme was initiated in Brazil in the mid-1970s and proved successful in terms of morbidity control, as the number of cases with hepato-splenic involvement was reduced significantly. ...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2013.12.007
更新日期:2014-04-01 00:00:00
abstract::Resistance of trypanosomes to melarsoprol is ascribed to reduced uptake of the drug via the P2 nucleoside transporter. The aim of this study was to look for evidence of drug resistance in Trypanosoma brucei gambiense isolates from sleeping sickness patients in Ibba, South Sudan, an area of high melarsoprol failure rat...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2007.07.007
更新日期:2007-11-01 00:00:00
abstract::This study aimed to investigate the prevalence of cercarial infections in freshwater snails collected from the Chai Nat province of Central Thailand. Moreover, we aimed to develop a duplex PCR technique, using the ITS2 and candidate MT-ND1 gene, to determine the dissemination of H. taichui and H. pumilio, respectively...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2020.105795
更新日期:2020-12-10 00:00:00
abstract::Opisthorchis viverrini infection, opisthorchiasis, is a food-borne trematodiasis that is the main cause of cholangiocarcinoma, a bile duct cancer, in the Lower Mekong sub-region of Lao PDR, Cambodia, Vietnam, and Thailand. Despite extensive research on opisthorchiasis, the eradication of this disease has yet to be ach...
journal_title:Acta tropica
pub_type: 杂志文章,评审
doi:10.1016/j.actatropica.2019.05.011
更新日期:2019-08-01 00:00:00
abstract::A schistosomiasis control project was undertaken from 1994 to 1998 in Guruve District, Zimbabwe, based on the active involvement of local communities in the growing and application of the molluscicidal plant Phytolacca dodecandra as a supplement to other control measures such as chemotherapy and health education. The ...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/s0001-706x(02)00256-5
更新日期:2003-03-01 00:00:00
abstract::Population replacement/elimination strategies based on mass-release of sterile or otherwise genetically modified (male) mosquitoes are being considered in order to expand the malaria vector control arsenal on the way to eradication. A challenge in this context, is to produce male mosquitoes that will be able to compet...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2013.11.014
更新日期:2014-04-01 00:00:00
abstract::The involvement of the central nervous system (CNS) by Schistosoma mansoni may or may not cause clinical manifestations. When symptomatic, neuroschistosomiasis mansoni (NSM) is one of the most severe presentations of this infection. The neurological manifestations are due to numerous granulomas grouped in confined are...
journal_title:Acta tropica
pub_type: 杂志文章,评审
doi:10.1016/j.actatropica.2008.04.007
更新日期:2008-11-01 00:00:00
abstract::The geographical distribution of snail (i.e., the intermediate host of schistosomiasis) is consistent with that of endemic areas. The suitable snail habitus requires necessary environmental conditions for snail population. The high-resolution remote sensing provides an important tool for the spatio-temporal analysis o...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2019.105077
更新日期:2019-10-01 00:00:00
abstract::Schistosoma mansoni, being transmitted by some freshwater Biomphalaria snails, is a major causative agent of human schistosomiasis. In the absence of effective vaccine and alternative drug designs to fight against the disease, and with the limitations of molluscicide application, developing more efficient strategies t...
journal_title:Acta tropica
pub_type: 杂志文章,评审
doi:10.1016/j.actatropica.2017.07.021
更新日期:2017-12-01 00:00:00
abstract::The presentation of the World Health Organization (WHO)'s roadmap for neglected tropical diseases (NTDs) in January 2012 raised optimism that many NTDs can indeed be eliminated. To make this happen, the endemic, often low-income countries with still heavy NTD burdens must substantially strengthen their health systems....
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2014.09.017
更新日期:2015-01-01 00:00:00
abstract::Parenteral quinine is the most frequently used first line treatment for severe Plasmodium falciparum malaria in the developed world. Quinine is known to have a number of toxic side effects including cardiotoxicity, ototoxicity and ocular toxicity. Many therefore advocate routine monitoring of quinine levels for patien...
journal_title:Acta tropica
pub_type: 杂志文章,评审
doi:10.1016/j.actatropica.2005.11.006
更新日期:2006-02-01 00:00:00
abstract::Manipulating the endogenous immune responses of the mosquito such as temporal and spatial expression of antimicrobial peptides may help in the development of a refractory mosquito, unable to transmit malaria. In mosquito several small antimicrobial peptides are activated locally in the midgut and salivary glands upon ...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2008.01.001
更新日期:2008-04-01 00:00:00
abstract::This paper reviews various imaging techniques in different organs. Ultrasound is the most popular and readily available technique. Special emphasis is given to computerized tomography (CT) and magnetic resonance imaging (MRI) findings and their advantages for a confident diagnosis and treatment. ...
journal_title:Acta tropica
pub_type: 杂志文章,评审
doi:10.1016/s0001-706x(97)00052-1
更新日期:1997-09-15 00:00:00