Recent developments in tritium incorporation for radiotracer studies.

Abstract:

:The essential nature of rapid radiotracer synthesis very early in drug discovery programs has driven the need for better and more varied tritium incorporation methods. This review presents a summary of recent advances for tritium introduction via tritiated water, tritium gas, complex tritides, and a range of recently improved tritiation reagents. Access to a wider range of tritiated reagents (for tritioacetylation, tritioformylation, methylation, etc.) and commercial manifolds for the transfer and use of tritium gas is also discussed.

journal_name

Curr Pharm Des

authors

Saljoughian M,Williams PG

doi

10.2174/1381612003399969

subject

Has Abstract

pub_date

2000-07-01 00:00:00

pages

1029-56

issue

10

eissn

1381-6128

issn

1873-4286

journal_volume

6

pub_type

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