Ossification centers of human femur.

abstract：:The aim of this study was to investigate bone mineral density (BMD) and bone turnover in patients with primary knee osteoarthritis (KOA) and to compare them with generalized OA (GOA) and nonGOA patients. A total of 88 postmenopausal primary KOA patients were studied. OA was graded by using knee radiographs. BMD of the...

journal_title：Calcified tissue international

authors： Naitou K,Kushida K,Takahashi M,Ohishi T,Inoue T

更新日期：2000-05-01 00:00:00

abstract：:We compared the effects of four vitamin D metabolites, 1 alpha,25 dihydroxy vitamin D3 (1 alpha,25(OH)2D3), 1 alpha hydroxy vitamin D3 (1 alpha OH D3), 25 hydroxy vitamin D3 (25 OH D3), and 24R,25 dihydroxy vitamin D (24R,25(OH)sD3) on resorption and collagen synthesis in fetal rat bone maintained in organ culture. Re...

journal_title：Calcified tissue international

authors： Raisz LG,Kream BE,Smith MD,Simmons HA

更新日期：1980-01-01 00:00:00

abstract：:Results from previous quasi-static mechanical tests indicate that femurs from elderly subjects fail in vitro at forces 50% below those available in a fall from standing height. However, bone is a rate-dependent material, and it is not known whether this imbalance is present at rates of loading which occur in a fall. B...

journal_title：Calcified tissue international

authors： Courtney AC,Wachtel EF,Myers ER,Hayes WC

更新日期：1994-07-01 00:00:00

abstract：:Pleiotrophin (PTN) was found to have potent effects on regulation of osteoblast recruitment, proliferation and differentiation. The present study examined the long-term effects of targeted PTN over-expression on bone development and repair in a transgenic mouse model. Femurs and tibiae from the PTN transgenic mice and...

journal_title：Calcified tissue international

authors： Li G,Bunn JR,Mushipe MT,He Q,Chen X

更新日期：2005-04-01 00:00:00

abstract：:A case-control study was undertaken to understand the etiopathology of the bone deformities among young children in a fluoride-affected village of the Bihar State. Two villages were selected: one village with high fluoride in drinking water (7.9 +/- 4.15 ppm), and the other village with normal levels of fluoride (0.6 ...

journal_title：Calcified tissue international

authors： Khandare AL,Harikumar R,Sivakumar B

更新日期：2005-06-01 00:00:00

abstract：:Abnormal PTH secretion and cell growth in hyperparathyroid tissues are accompanied with reduced expression of Ca2+-sensing receptor (CaR) which plays a key role in Ca-regulated PTH release. In this study, we examined the receptor expression in parathyroid adenomas using specific anti-CaR antibody and investigated rela...

journal_title：Calcified tissue international

authors： Kaneko C,Mizunashi K,Tanaka M,Uzuki M,Kikuchi M,Sawai T,Goto MM

更新日期：1999-03-01 00:00:00

abstract：:Osteoporosis is characterized by low bone mass and a deterioration of bone architecture and likely is influenced by genetic factors. The ovariectomized (OVX) mouse is well suited for osteoporosis research, as shown to date by cross-sectional studies. Here, we investigate longitudinal changes by in vivo micro-computed ...

journal_title：Calcified tissue international

authors： Klinck J,Boyd SK

更新日期：2008-07-01 00:00:00

abstract：:Age-related loss of skeletal muscle is associated with increased risk of functional limitation and cardiovascular (CV) mortality. In the elderly abdominal aortic calcification (AAC) can increase CV risk by altering aortic properties which may raise blood pressure and increase cardiac workload. This study investigated ...

journal_title：Calcified tissue international

authors： Rodríguez AJ,Scott D,Khan B,Khan N,Hodge A,English DR,Giles GG,Ebeling PR

更新日期：2016-10-01 00:00:00

abstract：:Hypophosphatemic rickets (HR) is a group of rare disorders caused by excessive renal phosphate wasting. The purpose of this cross-sectional study of 38 HR patients was to characterize the phenotype of adult HR patients. Moreover, skeletal and endodontic severity scores were defined to assess possible gender difference...

journal_title：Calcified tissue international

authors： Beck-Nielsen SS,Brusgaard K,Rasmussen LM,Brixen K,Brock-Jacobsen B,Poulsen MR,Vestergaard P,Ralston SH,Albagha OM,Poulsen S,Haubek D,Gjørup H,Hintze H,Andersen MG,Heickendorff L,Hjelmborg J,Gram J

更新日期：2010-08-01 00:00:00

abstract：:Twenty-five female Caucasians, aged 19-57 years, with the hypermobility syndrome had bone density measurements using established noninvasive techniques such as dual X-ray absorptiometry (DXA), single photon absorptiometry (SPA), heel ultrasound (US), and peripheral computed tomography (pQCT) acquisitions of the radius...

journal_title：Calcified tissue international

authors： Nijs J,Van Essche E,De Munck M,Dequeker J

更新日期：2000-07-01 00:00:00

abstract：:Calcium-acidic phospholipid-phosphate complexes (Ca-PL-PO4) cause hydroxyapatite (HA) deposition in vitro. The acidic phospholipids--phosphatidylserine (PS), phosphatidylinositol (PI), phosphatidylglycerol (PG), and diphosphatidylglycerol (DPG)--all form Ca-PL-PO4 complexes: Nonacidic phospholipids--sphingomyelin (SPL...

journal_title：Calcified tissue international

authors： Boskey AL,Posner AS

更新日期：1982-01-01 00:00:00

abstract：:This article reviews the effects of restrictive eating disorders on bone health. The relationship between eating disorders and amenorrhea is discussed in detail. The pathologic impact of malnutrition on bone is explored by examining the results of studies using various available imaging techniques. The multiple hormon...

journal_title：Calcified tissue international

authors： Thornton D,Gordon CM

更新日期：2017-05-01 00:00:00

abstract：:A number of osteoporotic patients under bisphosphonate treatment present persistent fragility fractures and bone loss despite good compliance. The objective of this 18-month prospective study was to investigate the effect of teriparatide [rhPTH(1-34)] in 25 female osteoporotics who were inadequate responders to oral b...

journal_title：Calcified tissue international

authors： Jobke B,Muche B,Burghardt AJ,Semler J,Link TM,Majumdar S

更新日期：2011-08-01 00:00:00

abstract：:We have examined the effect of the anti-tumor compound taxol, on osteoclastic bone resorption. In the bone slice assay, taxol (0.1-0.001 microM) dose-dependently inhibited bone resorption with an IC50 of 0.08 microM. Osteoclast survival on bone slices was unaffected by 0.01-1 microM taxol, but 10 microM was cytotoxic....

journal_title：Calcified tissue international

authors： Hall TJ,Jeker H,Schaueblin M

更新日期：1995-12-01 00:00:00

abstract：:This study aimed to evaluate the association between objectively measured habitual physical activity and calcaneal and forearm bone mineral density (BMD, g/cm(2)), one mechanically more loaded and one less loaded skeletal region, in children aged 6-8 years. BMD was measured in 297 boys and 265 girls by peripheral dual...

journal_title：Calcified tissue international

authors： Hasselstrøm H,Karlsson KM,Hansen SE,Grønfeldt V,Froberg K,Andersen LB

更新日期：2007-01-01 00:00:00

abstract：:The aim of this study was to evaluate the association among phalangeal morphometric parameters, amplitude-dependent speed of sound (AD-SOS), ultrasound bone profile index (UBPI), and spinal bone mineral density (BMD) and fracture status. One hundred women (controls, mean age 53 +/- 12 years) and 40 osteoporotic women ...

journal_title：Calcified tissue international

authors： Guglielmi G,Njeh CF,de Terlizzi F,De Serio DA,Scillitani A,Cammisa M,Fan B,Lu Y,Genant HK

更新日期：2003-04-01 00:00:00

abstract：:The European Forsteo Observational Study was designed to examine the effectiveness of teriparatide in postmenopausal women with osteoporosis treated for up to 18 months in normal clinical practice in eight European countries. The incidence of clinical vertebral and nonvertebral fragility fractures, back pain, and heal...

journal_title：Calcified tissue international

authors： Langdahl BL,Rajzbaum G,Jakob F,Karras D,Ljunggren O,Lems WF,Fahrleitner-Pammer A,Walsh JB,Barker C,Kutahov A,Marin F

更新日期：2009-12-01 00:00:00

abstract：:We assessed the relationship of bone density and microarchitecture between hand, peripheral, and axial skeletal sites using high-resolution peripheral quantitative computed tomography (HR-pQCT) and dual-energy X-ray absorptiometry (DXA) in patients with rheumatoid arthritis (RA) and which factors influence these param...

journal_title：Calcified tissue international

authors： Zhu TY,Griffith JF,Qin L,Hung VW,Fong TN,Kwok AW,Leung PC,Li EK,Tam LS

更新日期：2012-11-01 00:00:00

abstract：:Prosected vertebrae and phalanges from 32 cadavera were examined using noninvasive methods commonly used for assessment of osteoporosis. Bone measures were then compared with a strength variable obtained by mechanically crushing or breaking the bones. All of the phalangeal density assessment techniques were found to b...

journal_title：Calcified tissue international

authors： Oyster N,Smith FW

更新日期：1988-08-01 00:00:00

abstract：:Micro-computed tomography (microCT) has become a standard tool for the evaluation of bone morphology in preclinical studies. Unfortunately, the user-dependent definition of contour lines that separate trabecular from cortical bone is not only extremely time-consuming but may also represent a source of data bias and in...

journal_title：Calcified tissue international

authors： Lublinsky S,Ozcivici E,Judex S

更新日期：2007-10-01 00:00:00

abstract：:Human osteoblasts were obtained by migration and proliferation of cells from embryonic membranous bone on glass fragments. Light and electron microscopy analyses revealed a typical osteoblast-like appearance with high protein synthesis activity. The cells showed high alkaline phosphatase activity that was associated w...

journal_title：Calcified tissue international

authors： Oliva A,Marrone G,Della Ragione F,Riccio V,Palumbo R,Rossano F,Zappia V

更新日期：1992-11-01 00:00:00

abstract：:This study aimed to investigate the effects of recombinant human bone morphogenetic protein (rhBMP-7) on human cancellous bone grafts (BGs) while differentiating between anabolic and catabolic events. Human BGs alone or supplemented with rhBMP-7 were harvested 14 weeks after subcutaneous implantation into NOD/Scid mic...

journal_title：Calcified tissue international

authors： Lahr CA,Wagner F,Shafiee A,Rudert M,Hutmacher DW,Holzapfel BM

更新日期：2019-09-01 00:00:00

abstract：:The purpose of this study was to establish the smallest dose of nasally administered salmon calcitonin (SCT) which, if given in conjunction with a previously published calcium/thiazide treatment, would be as effective as parenteral SCT in the treatment of Paget's disease of bone. Forty patients suffering from symptoma...

journal_title：Calcified tissue international

authors： Evans RA,Somers NM,Dunstan CR,Hills E,Evans M

更新日期：1991-09-01 00:00:00

abstract：:Several rare inherited disorders have been described that show phenotypic overlap with Paget's disease of bone (PDB) and in which PDB is a component of a multisystem disorder affecting muscle and the central nervous system. These conditions are the subject of this review article. Insertion mutations within exon 1 of t...

journal_title：Calcified tissue international

authors： Ralston SH,Taylor JP

更新日期：2019-05-01 00:00:00

abstract：:We studied the relationship between serum calcium (Ca) and parathyroid hormone (PTH) in patients with idiopathic hypoparathyroidism (IHP) to investigate the diversity of the degree of parathyroid insufficiency and a regulation of PTH secretion by Ca in IHP. Serum intact PTH concentrations ranged from < 1.0 to 10.3 pg/...

journal_title：Calcified tissue international

authors： Mizunashi K,Furukawa Y,Abe K,Yoshinaga K

更新日期：1993-12-01 00:00:00

abstract：:The tumor-suppressor p53 is a transcription factor that regulates a number of genes in the process of cell-cycle inhibition, apoptosis, and DNA damage. Recent studies have revealed a crucial role for p53 in bone remodeling. In our previous studies we have shown that p53 is an important regulator of osteoblast differen...

journal_title：Calcified tissue international

authors： Chen H,Hays E,Liboon J,Neely C,Kolman K,Chandar N

更新日期：2011-11-01 00:00:00

abstract：:The extractions of 85Sr2+, 18F-, sucrose-14C, EDTA-51Cr, and antipyrine-14C in bone were determined by the multiple indicator-dilution method. Fluoride and strontium extractions were 18 to 70% during a single transcapillary passage, and those of EDTA and sucrose were from 11 to 59%, whereas extraction of antipyrine wa...

journal_title：Calcified tissue international

authors： Lemon GJ,Davies DR,Hughes SP,Bassingthwaighte JB,Kelly PJ

更新日期：1980-01-01 00:00:00

abstract：:Yerba mate (Ilex paraguariensis) is a xanthine-containing beverage, which is also rich in caffeine. Because caffeine has a negative impact on bone mineral density (BMD) mainly associated with low calcium (Ca) diets, there would be expected a negative effect of yerba mate on bone. In this study, Sprague-Dawley rats wer...

journal_title：Calcified tissue international

authors： Brun LR,Brance ML,Lombarte M,Maher MC,Di Loreto VE,Rigalli A

更新日期：2015-11-01 00:00:00

abstract：:Inoculation of Moloney murine sarcoma virus (M-MSV) into shank muscles of adult NMRI mice resulted in localized sarcoma and periosteal membrane proliferation with subsequent periosteal bone formation. Newly formed bone arose from outer surface of shank bones. Two weeks after M-MSV inoculation the width of bone cortex ...

journal_title：Calcified tissue international

authors： Włodarski K,Kobus M,Luczak M,Dołowy J

更新日期：1981-01-01 00:00:00

abstract：:Ultrasound measurements of the calcaneus are related to incidence of osteoporotic fracture. Such measurements are generally made at fixed coordinates relative to a footplate. This study compares measurements at an anatomically located region of interest (ROIanat) and at fixed coordinates (ROIfixed), with bone mineral ...

journal_title：Calcified tissue international

authors： Brooke-Wavell K,Jones PR,Pye DW

更新日期：1995-07-01 00:00:00