Abstract:
:Although patients with schizophrenia have reduced brain size, there is no conclusive evidence that they have reduced head size. This begs the question: 'What is the precise relationship between head size and brain size?' We used a unique osteological collection to explore the relationship between external head measures and cranial capacity. The external measures accounted for, at most, 60% of the variance in cranial capacity - a value low enough to question the oft-assumed tight relationship between head measures and brain size. Obviously, various tissues and spaces [skull, sinus, muscle (frontalis, temporalis and occipitalis), subcutaneous fat and epidermal layers] contribute to head size without contributing to brain volume. The contribution of these other tissues and spaces tends to decrease the signal and increase the noise in the estimation of brain volume. Thus, it is understandable that patients with schizophrenia can have reduced cranial capacity and not reduced head size.
journal_name
Schizophr Resjournal_title
Schizophrenia researchauthors
Friedman L,Wiechers IR,Cerny CA,Schulz SC,Buckley Pdoi
10.1016/s0920-9964(99)00098-5subject
Has Abstractpub_date
2000-03-16 00:00:00pages
1-6issue
1eissn
0920-9964issn
1573-2509pii
S0920-9964(99)00098-5journal_volume
42pub_type
杂志文章abstract:BACKGROUND:Superior temporal gyrus (STG/BA22) volume is reduced in schizophrenia and to a milder degree in schizotypal personality disorder (SPD), representing a less severe disorder in the schizophrenia spectrum. SPD and Borderline personality disorder (BPD) are severe personality disorders characterized by social and...
journal_title:Schizophrenia research
pub_type: 杂志文章
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更新日期:2009-07-01 00:00:00
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journal_title:Schizophrenia research
pub_type: 杂志文章,meta分析
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journal_title:Schizophrenia research
pub_type: 杂志文章
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更新日期:2008-02-01 00:00:00
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journal_title:Schizophrenia research
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journal_title:Schizophrenia research
pub_type: 临床试验,杂志文章
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journal_title:Schizophrenia research
pub_type: 杂志文章
doi:10.1016/j.schres.2016.04.050
更新日期:2016-11-01 00:00:00
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journal_title:Schizophrenia research
pub_type: 杂志文章
doi:10.1016/s0920-9964(00)00002-5
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journal_title:Schizophrenia research
pub_type: 杂志文章
doi:10.1016/j.schres.2013.12.014
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journal_title:Schizophrenia research
pub_type: 杂志文章
doi:10.1016/j.schres.2011.03.034
更新日期:2011-08-01 00:00:00
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journal_title:Schizophrenia research
pub_type: 杂志文章,meta分析,评审
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更新日期:2012-06-01 00:00:00
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journal_title:Schizophrenia research
pub_type: 杂志文章
doi:10.1016/s0920-9964(98)00142-x
更新日期:1999-02-15 00:00:00
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journal_title:Schizophrenia research
pub_type: 杂志文章
doi:10.1016/j.schres.2019.08.009
更新日期:2019-10-01 00:00:00
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journal_title:Schizophrenia research
pub_type: 杂志文章,多中心研究
doi:10.1016/j.schres.2014.09.042
更新日期:2015-04-01 00:00:00
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journal_title:Schizophrenia research
pub_type: 杂志文章
doi:10.1016/j.schres.2015.06.027
更新日期:2015-10-01 00:00:00
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journal_title:Schizophrenia research
pub_type: 杂志文章,评审
doi:10.1016/j.schres.2014.06.027
更新日期:2016-09-01 00:00:00
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journal_title:Schizophrenia research
pub_type: 杂志文章
doi:10.1016/j.schres.2011.08.004
更新日期:2011-12-01 00:00:00
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journal_title:Schizophrenia research
pub_type: 杂志文章
doi:10.1016/j.schres.2006.04.001
更新日期:2006-07-01 00:00:00
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journal_title:Schizophrenia research
pub_type: 杂志文章,多中心研究
doi:10.1016/j.schres.2013.12.004
更新日期:2014-02-01 00:00:00
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journal_title:Schizophrenia research
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.schres.2019.07.013
更新日期:2019-09-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/0920-9964(93)90008-7
更新日期:1993-03-01 00:00:00
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journal_title:Schizophrenia research
pub_type: 杂志文章
doi:10.1016/j.schres.2009.09.002
更新日期:2009-12-01 00:00:00
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journal_title:Schizophrenia research
pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2011-02-01 00:00:00
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journal_title:Schizophrenia research
pub_type: 杂志文章
doi:10.1016/0920-9964(94)90067-1
更新日期:1994-05-01 00:00:00
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journal_title:Schizophrenia research
pub_type: 杂志文章
doi:10.1016/j.schres.2015.08.029
更新日期:2015-10-01 00:00:00
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journal_title:Schizophrenia research
pub_type: 杂志文章
doi:10.1016/s0920-9964(98)00106-6
更新日期:1998-11-30 00:00:00
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pub_type: 杂志文章,随机对照试验
doi:10.1016/j.schres.2017.09.012
更新日期:2019-01-01 00:00:00
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journal_title:Schizophrenia research
pub_type: 杂志文章
doi:10.1016/0920-9964(93)90022-b
更新日期:1993-01-01 00:00:00
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journal_title:Schizophrenia research
pub_type: 杂志文章
doi:10.1016/j.schres.2006.03.001
更新日期:2006-07-01 00:00:00