Abstract:
:We evaluated the association of Chlamydia pneumoniae (CP) infection with progression of diabetic nephropathy. Type 2 diabetic patients (60) were divided into two groups, those with incipient nephropathy and those with advanced nephropathy, based on the severity of diffuse glomerular lesions using Gellman's criteria. Type 2 (34) diabetic patients without nephropathy (normoalbuminuria) and 59 nondiabetics served as control groups. Serum IgG-antibody against CP was measured using ELISA. CP antibody was detected in 45.8% of nondiabetic controls, in 47.1% of diabetic patients without nephropathy, in 52.6% of diabetic patients with incipient nephropathy, and 78% of diabetic patients with advanced nephropathy. There was 4.22-fold increase in the risk of advanced nephropathy associated with the presence of CP antibody. Our findings indicate an association between chronic CP infection and advanced diabetic nephropathy.
journal_name
Diabetes Res Clin Practjournal_title
Diabetes research and clinical practiceauthors
Kanauchi M,Kawano T,Dohi Kdoi
10.1016/s0168-8227(99)00108-4subject
Has Abstractpub_date
2000-01-01 00:00:00pages
45-8issue
1eissn
0168-8227issn
1872-8227pii
S0168-8227(99)00108-4journal_volume
47pub_type
杂志文章abstract::Previously, we have reported that the lipoprotein fraction containing intermediate density lipoprotein (IDL) and low density lipoprotein (LDL) isolated from diabetics stimulates an atherogenic cytokine in cultured endothelial cells. To study which lipoprotein fraction isolated from diabetics can modulate the gene expr...
journal_title:Diabetes research and clinical practice
pub_type: 杂志文章
doi:10.1016/s0168-8227(99)00147-3
更新日期:2000-05-01 00:00:00
abstract::In the last decades the survival rate of patients diagnosed with cancer - both in childhood and adulthood - significantly improved, leading to a growing number of cancer survivors (CS) within general population. Despite the better survival rate related to the cancer diagnosis, CS show increased mortality and morbidity...
journal_title:Diabetes research and clinical practice
pub_type: 杂志文章,评审
doi:10.1016/j.diabres.2018.02.016
更新日期:2018-09-01 00:00:00
abstract:AIMS:The aim of the present study was to determine the prevalence of abnormal glucose tolerance and the metabolic syndrome in a cohort of previously gestational diabetic (GDM) women 4 years after delivery. METHODS:Sixty-eight prior GDM and a control group of 39 women with normal glucose tolerance during pregnancy were...
journal_title:Diabetes research and clinical practice
pub_type: 杂志文章
doi:10.1016/j.diabres.2009.05.001
更新日期:2009-08-01 00:00:00
abstract::In a case-control analysis comparing 303 patients with diabetes and 303 without (matched on age, race, sex and height), diabetics had reduced lung diffusion (DLCO) independent of smoking, obesity, clinical heart failure, asymptomatic left ventricular systolic and diastolic dysfunction: DLCO (mean±SE: 15.5±0.9 vs. 16.4...
journal_title:Diabetes research and clinical practice
pub_type: 杂志文章
doi:10.1016/j.diabres.2012.02.014
更新日期:2012-06-01 00:00:00
abstract:AIM:To describe coverage, cost and care of type 1 diabetes (T1D) in 2 regions of China--Beijing and Shantou--including: METHODS:This is a mixed-methods descriptive study with three arms--coverage, cost and care. It is taking place in 4 tertiary hospitals, 3 secondary hospitals and 4 primary health facilities in Beijin...
journal_title:Diabetes research and clinical practice
pub_type: 杂志文章,多中心研究
doi:10.1016/j.diabres.2011.10.016
更新日期:2011-11-01 00:00:00
abstract:OBJECTIVE:To examine the association between screen time and the metabolic syndrome (MetS) in a nationally representative sample of children and adolescents. METHODS:A cross-sectional survey was conducted in 845 children and adolescents (10-18 years of age) from the 2005 Korean National Health and Nutrition Examinatio...
journal_title:Diabetes research and clinical practice
pub_type: 杂志文章
doi:10.1016/j.diabres.2010.02.016
更新日期:2010-07-01 00:00:00
abstract:AIMS:Aim of the study was to determine the role of perfusion chest computed tomography (pCT) in evaluation of pulmonary diabetic angiopathy. METHODS:18 never-smoking patients (10 diabetic patients and 8 healthy controls) underwent chest high resolution CT (HRCT) and then pCT scanning. In both groups, blood tests, bioc...
journal_title:Diabetes research and clinical practice
pub_type: 杂志文章
doi:10.1016/j.diabres.2010.11.004
更新日期:2011-01-01 00:00:00
abstract::The prevalence of diabetes mellitus (DM) and impaired glucose tolerance (IGT) and their relationship to age and obesity was estimated in a population-based survey in urban and rural areas in Baluchistan province, Pakistan. Cluster sampling of 834 adults (260 men, 574 women) in the urban and 570 adults (175 men, 395 wo...
journal_title:Diabetes research and clinical practice
pub_type: 杂志文章
doi:10.1016/s0168-8227(99)00017-0
更新日期:1999-04-01 00:00:00
abstract::Several models of blood glucose meters are available to diabetic patients. They all require several steps for their operation, which increases the potential for user error. A new meter (One Touch TM System, Lifescan Inc., a Johnson & Johnson Company, Mountain View, CA) was designed to minimise the operational steps an...
journal_title:Diabetes research and clinical practice
pub_type: 杂志文章
doi:10.1016/0168-8227(89)90045-4
更新日期:1989-06-20 00:00:00
abstract::Patients with diabetes mellitus have a higher rate of mortality than the general population. This higher mortality may be attributed mainly to cardiovascular disease. A high prevalence of dyslipidemia in diabetics can be one of the reasons for this. The most commonly recognized lipid abnormality in non-insulin-depende...
journal_title:Diabetes research and clinical practice
pub_type: 杂志文章,评审
doi:10.1016/0168-8227(96)01263-6
更新日期:1996-06-01 00:00:00
abstract:INTRODUCTION:The COVID-19 pandemic has forced governments to take exceptional measures to minimize its spread, imposing lockdown policies. The aim of this study was to evaluate the impact of lockdown on type 1 diabetes (T1D) glycemic control. MATERIAL AND METHODS:People with T1D using flash glucose monitoring were inc...
journal_title:Diabetes research and clinical practice
pub_type: 杂志文章
doi:10.1016/j.diabres.2020.108348
更新日期:2020-08-01 00:00:00
abstract:AIMS:The objective of the present analysis was to evaluate and quantify the risk for gestational diabetes mellitus (GDM) according to maternal age. METHODS:Three electronic databases were searched for publications from inception to July 2018. Odds ratio (OR) and 95% confidence interval (95% CI) were calculated. A dose...
journal_title:Diabetes research and clinical practice
pub_type: 杂志文章,meta分析
doi:10.1016/j.diabres.2020.108044
更新日期:2020-04-01 00:00:00
abstract:AIMS:Insulin resistance (IR) and sympathetic over-activation play a critical role in diabetic cardiomyopathy (DCM). Percutaneous renal sympathetic denervation (RDN) was tested to treat refractory hypertension. However, the benefits of RDN for DCM and IR still remain unknown. The present study aimed to investigate the e...
journal_title:Diabetes research and clinical practice
pub_type: 杂志文章
doi:10.1016/j.diabres.2015.12.012
更新日期:2016-05-01 00:00:00
abstract::We studied cognition in the Finnish Diabetes Prevention Study (DPS), a trial of lifestyle intervention that prevented diabetes in persons with impaired glucose tolerance. Cognition was similar in the randomization arms 9 years after the intervention in 364 participants, suggesting that the intervention did not benefit...
journal_title:Diabetes research and clinical practice
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.diabres.2015.02.023
更新日期:2015-06-01 00:00:00
abstract::We report a case of chronic hepatitis C presenting insulin-dependent diabetes mellitus (IDDM) associated with various autoantibodies including possible anti-insulin receptor antibody (AIRA) during interferon (IFN) therapy. A 57-year-old man having chronic hepatitis C virus (HCV) infection with chronic thyroiditis rece...
journal_title:Diabetes research and clinical practice
pub_type: 杂志文章
doi:10.1016/s0168-8227(00)00143-1
更新日期:2000-08-01 00:00:00
abstract:AIMS:To investigate experiences of people with type 2 diabetes (T2DM) at the clinic visit when an additional oral antidiabetes drug (OAD) is prescribed, and how this affects their quality of life, self-management and key outcomes. METHODS:We surveyed adults with T2DM from a large multinational study of patient-physici...
journal_title:Diabetes research and clinical practice
pub_type: 杂志文章
doi:10.1016/j.diabres.2019.01.020
更新日期:2019-03-01 00:00:00
abstract:AIM:To summarize the existing literature concerning the association between polypharmacy and adverse health consequences in elderly patients with type 2 diabetes mellitus. METHODS:We searched four literature databases (PubMed/Medline, ScienceDirect and Web of Science) through April 2019. We included all studies that a...
journal_title:Diabetes research and clinical practice
pub_type: 杂志文章,meta分析
doi:10.1016/j.diabres.2019.107804
更新日期:2019-09-01 00:00:00
abstract::The aim of this study was to examine distinctive clinical characteristics of non-insulin dependent diabetes mellitus (NIDDM) patients in Kuwait including mode of presentation at diagnosis, family history of diabetes, therapeutic management and response to treatment. We studied 3299 Kuwaiti patients (1454 male (M) and ...
journal_title:Diabetes research and clinical practice
pub_type: 杂志文章
doi:10.1016/0168-8227(95)01128-5
更新日期:1995-08-01 00:00:00
abstract:BACKGROUND:High sensitivity C-reactive protein (hsCRP) is more sensitive than standard C-reactive protein (CRP) assay in evaluating the risk of coronary heart disease and other atherosclerotic events. By this time, there are several reports that type 2 diabetic subjects have higher serum levels of hsCRP than those of n...
journal_title:Diabetes research and clinical practice
pub_type: 杂志文章
doi:10.1016/j.diabres.2004.05.009
更新日期:2004-12-01 00:00:00
abstract:OBJECTIVE:Clinical trials have demonstrated that in individuals with type 1 diabetes the use of CSII pump resulted in better glucose control. Advantages of pumps therapy include many features such as the bolus calculators (wizard). These features are optional and therefore it is important to determine whether their use...
journal_title:Diabetes research and clinical practice
pub_type: 杂志文章
doi:10.1016/j.diabres.2011.01.002
更新日期:2011-04-01 00:00:00
abstract:AIMS:The aim of this study was to investigate the effect of yoga intervention on the biochemical, oxidative stress markers and inflammatory markers and sleep quality among subjects with type 2 diabetes. METHODS:Subjects with type 2 diabetes attending a tertiary care centre for diabetes during Feb 2017 to Oct 2019 in C...
journal_title:Diabetes research and clinical practice
pub_type: 杂志文章
doi:10.1016/j.diabres.2020.108644
更新日期:2020-12-25 00:00:00
abstract:OBJECTIVE:To investigate the changes of serum anti-aging protein Klotho and neutrophil gelatinase-associated lipocalin (NGAL) levels and their correlation in type 2 diabetes mellitus (T2DM) patients at different stages of diabetic kidney disease (DKD) determined by urinary albuminuria. METHODS:462 cases with T2DM were...
journal_title:Diabetes research and clinical practice
pub_type: 杂志文章
doi:10.1016/j.diabres.2014.08.026
更新日期:2014-11-01 00:00:00
abstract:AIMS:To compare the ability of definitions of Metabolic Syndrome (MetS) in the prediction of type 2 diabetes. METHODS:We examined 4756 subjects in an Iranian population who were non-diabetic at baseline. After 3.6 years, 188 individuals developed diabetes. RESULTS:Impaired glucose tolerance (IGT) and MetS definitions...
journal_title:Diabetes research and clinical practice
pub_type: 杂志文章
doi:10.1016/j.diabres.2008.01.003
更新日期:2008-05-01 00:00:00
abstract::To assess whether plasma retinol-binding protein (RBP) is a marker of insulin resistance we measured RBP, insulin and glucose in 285 fasting subjects attending a Lipid Disorders Clinic as outpatients. They were grouped as either subjects without diabetes mellitus and with varying degrees of insulin resistance or subje...
journal_title:Diabetes research and clinical practice
pub_type: 杂志文章
doi:10.1016/j.diabres.2007.12.002
更新日期:2008-04-01 00:00:00
abstract:AIMS:We examined whether 0.9 mg/day liraglutide plus basal insulin (Lira-basal) is superior to basal-bolus insulin therapy (BBIT) for type 2 diabetes (T2DM) without severe insulin deficiency as determined by glucagon stimulation. METHODS:Fifty patients receiving BBIT were enrolled in this 24-week, prospective, randomi...
journal_title:Diabetes research and clinical practice
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.diabres.2018.03.032
更新日期:2018-06-01 00:00:00
abstract::Glucose-induced insulin secretion from beta-cells is often impaired in diabetic condition and by exposure to diabetogenic pharmacological agents. In pancreatic beta-cells, intracellular glucose metabolism regulates exocytosis of insulin granules, according to metabolism-secretion coupling in which glucose-induced mito...
journal_title:Diabetes research and clinical practice
pub_type: 杂志文章,评审
doi:10.1016/j.diabres.2007.01.026
更新日期:2007-09-01 00:00:00
abstract:AIMS:We evaluated quality of diabetes care in low- and middle-income countries (LMIC) of Central and South America by documenting the ability to meet the guideline-recommended targets. We also identified barriers to achieving goals of treatment and characteristics of successful programs. METHODS:We searched the Nation...
journal_title:Diabetes research and clinical practice
pub_type: 杂志文章,评审
doi:10.1016/j.diabres.2013.01.010
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND:Clinical trials have shown very modest short-term improvements in glycemic control among participants with diabetes after periodontitis treatment. Few longitudinal studies suggest that periodontitis may be related to prediabetes/diabetes risk. METHODS:We evaluated 1206 diabetes free participants in the San ...
journal_title:Diabetes research and clinical practice
pub_type: 杂志文章
doi:10.1016/j.diabres.2018.04.028
更新日期:2018-07-01 00:00:00
abstract:AIMS:To compare the abilities of Intergrowth-21st standards, Institute of Medicine (IOM) recommendations and a Chinese reference on gestational weight gain (GWG) to identify women at risk of gestational diabetes (GDM) and GDM-related adverse outcomes. METHODS:A retrospective cohort study was conducted on 13,366 women ...
journal_title:Diabetes research and clinical practice
pub_type: 杂志文章
doi:10.1016/j.diabres.2019.107912
更新日期:2019-12-01 00:00:00
abstract::We examined trends and associated factors of disability among Spanish elderly with diabetes from data of three National Health Surveys (NHS) from 2000 to 2007. Prevalence of disability was higher among diabetic elderly versus non-sufferers and increased over time. Adjusted OR for activities of daily living 1.66 (1.37-...
journal_title:Diabetes research and clinical practice
pub_type: 杂志文章
doi:10.1016/j.diabres.2011.07.024
更新日期:2011-11-01 00:00:00