Crossreactive neutralizing antibodies induced by immunization with caprine arthritis-encephalitis virus surface glycoprotein.

abstract：:The safety and immunogenicity of a single dose of virosome-formulated hepatitis A vaccine was evaluated in healthy seronegative Thai volunteers. Immunization elicited primarily mild transient reactions which did not interfere with normal activities. All subjects possessed > 20 mIU of anti-hepatitis A virus antibody pe...

journal_title：Vaccine

authors： Poovorawan Y,Theamboonlers A,Chumdermpadetsuk S,Glück R,Cryz SJ Jr

更新日期：1995-07-01 00:00:00

abstract：:As a step in the development of an oral vaccine against ETEC, we evaluated the safety and immunogenicity of CS6, a polymeric protein commonly found on the surface of ETEC. Formulations included 1 and 5mg doses of CS6, either encapsulated in biodegradable polymer poly(D, L)-lactide-co-glycolide (PLG), or as free protei...

journal_title：Vaccine

authors： Katz DE,DeLorimier AJ,Wolf MK,Hall ER,Cassels FJ,van Hamont JE,Newcomer RL,Davachi MA,Taylor DN,McQueen CE

更新日期：2003-01-17 00:00:00

abstract：:The development of live attenuated vaccines, allowing for the safe and effective immunisation at mucosal surfaces, is a strategy of great interest for vaccinologists. The main advantage of this approach over conventional parenteral vaccines is the induction of strong mucosal immune responses, allowing targeting of the...

journal_title：Vaccine

authors： Viret JF,Dietrich G,Favre D

更新日期：2004-06-23 00:00:00

abstract：:Insoluble, nanostructured delta inulin particles enhance the immunogenicity of co-administered protein antigens and consequently are used as a vaccine adjuvant (Advax™). To better understand their immunomodulatory properties, the in vitro hydrolysis and in vivo distribution of delta inulin particles were investigated....

journal_title：Vaccine

authors： Wang L,Barclay T,Song Y,Joyce P,Sakala IG,Petrovsky N,Garg S

更新日期：2017-08-03 00:00:00

abstract：:Pertussis vaccine development has mainly focused on Bordetella pertussis, and consequently these vaccines contain B. pertussis antigens only. However, the related species Bordetella parapertussis can also cause pertussis, although symptoms associated with the disease are generally considered to be milder. Recent field...

journal_title：Vaccine

authors： David S,van Furth R,Mooi FR

更新日期：2004-05-07 00:00:00

abstract：:A new microparticulate delivery system composed of a stabilizing gelatin/poloxamer microcore surrounded by a PLGA coat was designed to improve the stability of tetanus toxoid (TT) encapsulated in PLGA microspheres. Microcores were prepared by a spray-congealing technique and encapsulated within PLGA using an oil-in-oi...

journal_title：Vaccine

authors： Tobío M,Schwendeman SP,Guo Y,McIver J,Langer R,Alonso MJ

更新日期：1999-11-12 00:00:00

abstract：:Modified Vaccinia virus Ankara (MVA) is an attenuated strain of vaccinia virus that is being considered as a safer alternative to replicating vaccinia vaccine strains such as Dryvax(®) and ACAM2000. Its excellent safety profile and large genome also make it an attractive vector for the delivery of heterologous genes f...

journal_title：Vaccine

authors： Hermanson G,Chun S,Felgner J,Tan X,Pablo J,Nakajima-Sasaki R,Molina DM,Felgner PL,Liang X,Davies DH

更新日期：2012-01-11 00:00:00

abstract：OBJECTIVE:Implementing national-level vaccination programs involves long-term investment, which can be a significant financial burden, particularly in resource-limited settings. Although many studies have assessed the economic impacts of providing vaccinations, evidence on the positive and negative implications of huma...

journal_title：Vaccine

authors： Chootipongchaivat S,Chantarastapornchit V,Kulpeng W,Ceria JA,Tolentino NI,Teerawattananon Y

更新日期：2016-09-14 00:00:00

abstract：INTRODUCTION:Adolescents and young adults are at a high risk of developing human papillomavirus (HPV) infections, which can be prevented with the use of vaccines. Moreover, a combined immunization strategy for administration of HPV vaccines with other routine vaccines may lead to better compliance. We aim to comprehens...

journal_title：Vaccine

authors： Li Y,Zhu P,Wu M,Zhang Y,Li L

更新日期：2020-01-10 00:00:00

abstract：:Real, perceived and unknown adverse events secondary to vaccinations are a source of concern for care providers of children. In the USA large linked databases have provided helpful information regarding the safety of vaccines. Very little prospectively collected data on vaccine safety is available from resource poor c...

journal_title：Vaccine

authors： Ali M,Canh DG,Clemens JD,Park JK,von Seidlein L,Thiem VD,Tho le H,Trach DD

更新日期：2003-04-02 00:00:00

abstract：:One hundred healthy Caucasian medical students (age 22 +/- 1 years) were vaccinated with a recombinant hepatitis B vaccine and their haptoglobin types were determined. A relationship between haptoglobin type and immune response to the vaccine was observed. Subjects with a 2-2 haptoglobin phenotype produced significant...

journal_title：Vaccine

authors： Louagie H,Delanghe J,Desombere I,De Buyzere M,Hauser P,Leroux-Roels G

更新日期：1993-09-01 00:00:00

abstract：:To evaluate the usefulness of a DNA vaccine for chickens, we constructed a plasmid vector expressing the Newcastle disease virus F protein (NDV-F) under the control of the human cytomegalovirus immediate early enhancer and chicken beta-actin gene promoter. One-week-old chickens injected intramusculary with the circula...

journal_title：Vaccine

authors： Sakaguchi M,Nakamura H,Sonoda K,Hamada F,Hirai K

更新日期：1996-06-01 00:00:00

abstract：:Safety of and humoral immune response to the anti-influenza vaccine in coronary artery disease (CAD) patients were evaluated. The trivalent vaccine was administered to 137 eligible CAD patients and 67 age- and sex-matched healthy individuals. Antibody (Ab) titers were measured before and 1 month after vaccination. CAD...

journal_title：Vaccine

authors： Keshtkar-Jahromi M,Vakili H,Rahnavardi M,Gholamin S,Razavi SM,Eskandari A,Sadeghi R,Vatan-Pour H,Keshtkar-Jahromi M,Haghighat B,Ghaffaripour M,Mokhtari-Azad T

更新日期：2009-12-10 00:00:00

abstract：:In a severe pandemic, rapid production and deployment of vaccines will potentially be critical in mitigating the impact on populations and essential services. We compared access to vaccines and timing of delivery relative to identification of A(H1N1)pdm09 and the geographic progression of the pandemic in the WHO Europ...

journal_title：Vaccine

authors： Jorgensen P,Wasley A,Mereckiene J,Cotter S,Weber JT,Brown CS

更新日期：2013-08-28 00:00:00

abstract：:The ability to elicit humoral and cell-mediated immune (CMI) responses from DNA immunization by combinational use of codon optimization and C3d component of complement was evaluated in this study. DNA vaccines that express either the wild type or the codon optimized gp120 gene coding for the envelope (Env) glycoprotei...

journal_title：Vaccine

authors： Liu F,Mboudjeka I,Shen S,Chou TH,Wang S,Ross TM,Lu S

更新日期：2004-04-16 00:00:00

abstract：:The treatment effect against psoriasis of an antigen (delipidated, deglycolipidated form of M. vaccae-PVAC) was investigated. One hundred and sixty-five patients were enrolled in three arms (50 or 15 microg or placebo), each receiving a total of two intradermal injections (days 0 and 21). At week 12, a 75% decrease in...

journal_title：Vaccine

authors： Netto EM,Takahashi D,de Fátima Paim de Oliveira M,Barbosa P,Ferraz N,Paixão A,Oyafuso LK,Bortoletto C,Matos D,Paixão M,da Silva AO,Badaro R

更新日期：2006-06-05 00:00:00

abstract：:Respiratory syncytial virus is one of the major respiratory pathogens for infants and immunocompromized children. With the exception of young children, all the population has encountered RSV and is seropositive. Recent reports have demonstrated however that the virus also affects the elderly and represents a major cau...

journal_title：Vaccine

authors： Goestch L,Plotnicky-Gilquin H,Champion T,Beck A,Haeuw JF,Nguyen T,Bonnefoy JY,Corvaïa N

更新日期：2000-06-01 00:00:00

abstract：:Influenza becomes epidemic worldwide every year, and many individuals receive vaccination annually. Quality control relating to safety and potency of influenza vaccines is important to maintain public confidence. The safety of influenza vaccines has been assessed by clinical trials, and animal safety tests are perform...

journal_title：Vaccine

authors： Momose H,Sasaki E,Kuramitsu M,Hamaguchi I,Mizukami T

更新日期：2018-10-15 00:00:00

abstract：:The Salmonella rfc gene encodes the O-antigen polymerase. We constructed three strains in which we replaced the native rfc promoter with the arabinose-dependent araC P(BAD) promoter so that rfc expression was dependent on exogenously supplied arabinose provided during in vitro growth. The three mutant strains were des...

journal_title：Vaccine

authors： Kong Q,Liu Q,Jansen AM,Curtiss R 3rd

更新日期：2010-08-23 00:00:00

abstract：:In clinical trials, the specificity of the disease endpoint is critical to an accurate estimate of vaccine efficacy. We used a logistic regression model to analyse parasite densities among children before and after treatment with antimalarials, in order to estimate the impact that clearing asymptomatic parasitaemia ha...

journal_title：Vaccine

authors： Bejon P,Mwangi T,Lowe B,Peshu N,Hill AV,Marsh K

更新日期：2007-11-23 00:00:00

abstract：BACKGROUND:The Institute of Medicine, in a 2013 report, recommended that the Vaccine Safety Datalink (VSD) expand collaborations to include more diversity in the study population. Kaiser Permanente Colorado (KPCO), an established VSD site, partnered with Denver Health (DH), an integrated safety net healthcare system, t...

journal_title：Vaccine

authors： Narwaney KJ,Breslin K,Ross CA,Shoup JA,Wain KF,Weintraub ES,McNeil MM,Hambidge SJ

更新日期：2017-03-01 00:00:00

abstract：:A number of challenges for developing a protective pre-pandemic influenza A vaccine exists including predicting the target influenza strain and designing the vaccine for an immunologically naïve population. Manufacturing and supply of the vaccine would also require implementing ways to increase coverage for the larges...

journal_title：Vaccine

authors： Allen JD,Owino SO,Carter DM,Crevar CJ,Reese VA,Fox CB,Coler RN,Reed SG,Baldwin SL,Ross TM

更新日期：2017-09-12 00:00:00

abstract：:A synthetic T cell immunogen (TCI) has been designed as a candidate DNA-based vaccine against Human immunodeficiency virus (HIV)-1 using cytotoxic T lymphocytes (CD8(+) CTL) and T-helper lymphocytes (CD4(+) Th) epitopes retrieved from the Los Alamos HIV Molecular Immunology Database. The protein 392 amino acids in len...

journal_title：Vaccine

authors： Bazhan SI,Belavin PA,Seregin SV,Danilyuk NK,Babkina IN,Karpenko LI,Nekrasova NA,Lebedev LR,Ignatyev GM,Agafonov AP,Poryvaeva VA,Aborneva IV,Ilyichev AA

更新日期：2004-04-16 00:00:00

abstract：OBJECTIVE:To assess whether recipients and non-recipients of the human papillomavirus (HPV) vaccine subsequently differ in terms of sexual risk taking behaviour. DESIGN:Cross-sectional survey. Sequential analyses constructed from self-reported age at vaccination, age at first intercourse and age at response. SETTING:...

journal_title：Vaccine

authors： Hansen BT,Kjær SK,Arnheim-Dahlström L,Liaw KL,Jensen KE,Thomsen LT,Munk C,Nygård M

更新日期：2014-09-03 00:00:00

abstract：:During the pandemic (H1N1) 2009 vaccination campaign, vaccine providers collected immunization data using hybrid (paper-based and electronic methods) and electronic data systems. We measured staff time in seconds spent on data collection tasks to compare system efficiencies. The sample consisted of 38 organizations ac...

journal_title：Vaccine

authors： Quach S,Hamid JS,Pereira JA,Heidebrecht CL,Foisy J,Bettinger JA,Rosella L,Crowcroft NS,Deeks SL,Quan SD,Finkelstein M,Guay M,Buckeridge DL,Sikora CA,Kwong JC,Public Health Agency of Canada\/Canadian Institutes of Health Res

更新日期：2011-02-24 00:00:00

abstract：:Given the ethical aspects of vaccination policies and current threats to public trust in vaccination, it is important that governments follow clear criteria for including new vaccines in a national programme. The Health Council of the Netherlands developed such a framework of criteria in 2007, and has been using this ...

journal_title：Vaccine

authors： Verweij MF,Houweling H

更新日期：2014-12-12 00:00:00

abstract：:One hundred and fourteen children, born to HBsAg-positive mothers received in the first year of life passive active prophylaxis for hepatitis B virus (HBV). They have been followed up to 10 years. A booster dose given in a cohort at the 5th year does not seem to increase protection against HBV. No difference in immuno...

journal_title：Vaccine

authors： Resti M,Azzari C,Mannelli F,Rossi ME,Lionetti P,Vierucci A

更新日期：1997-08-01 00:00:00

abstract：:This study examines the potential clinical and economic benefits for adults arising from paediatric pneumococcal vaccination in the UK. A UK birth cohort model with a 10-year horizon and using a primary 4-dose paediatric 7-valent pneumococcal conjugate vaccine (PCV) schedule was populated with 1999 morbidity and morta...

journal_title：Vaccine

authors： McIntosh ED,Conway P,Willingham J,Hollingsworth R,Lloyd A

更新日期：2005-02-25 00:00:00

abstract：:We compared the protection afforded by three different DNA application methods against bovine respiratory syncytial virus (BRSV) infection in cattle. A synthetic gene that codes for the G protein of BRSV was inserted into a eukaryotic vector and was used in the vaccine. Intradermal (i.d.) application with a needleless...

journal_title：Vaccine

authors： Schrijver RS,Langedijk JP,Keil GM,Middel WG,Maris-Veldhuis M,Van Oirschot JT,Rijsewijk FA

更新日期：1998-01-01 00:00:00

abstract：:Europe is not ready for the next pandemic. Nonetheless, several positive developments are cause for optimism. The European Centre for Disease Control (ECDC) was founded in May 2005 and has explicitly identified influenza as one of its top four priorities. Europe is also taking steps to streamline the regulatory approv...

journal_title：Vaccine

authors：

更新日期：2006-11-10 00:00:00