Abstract：
:To examine the association between alcohol consumption and mortality in Japan, where mortality and lifestyle differ substantially from Western countries, a population-based prospective study was conducted in four public health center areas as part of the Japan Public Health Center-based prospective study on cancer and cardiovascular disease (JPHC). After excluding subjects with self-reported serious diseases at baseline, 19,231 men aged 40-59 years who reported their alcohol intake were followed from 1990 through 1996, and 548 deaths were documented. The association between all-cause mortality and alcohol consumption was J-shaped. The lowest risk was observed for men who consumed 1-149 g/week (relative risk (RR) = 0.64, 95% confidence interval (CI) 0.46, 0.88), while the highest risk was seen for men who consumed > or =450 g/week (RR = 1.32, 95% CI 1.00, 1.74), after adjustment for possible confounders. The association did not change after excluding deaths that occurred in the first 2 years of follow-up. However, the association was modified by smoking, and beneficial effects of moderate drinking were largely limited to nonsmokers. The risk of cancer death showed a similar trend, but increased more in heavy drinkers. The background characteristics of moderate drinkers were healthier than either nondrinkers or heavy drinkers. The authors conclude that moderate alcohol consumption was associated with the lowest risks of all-cause and cancer mortality, especially among nonsmokers.
journal_name
Am J Epidemioljournal_title
American journal of epidemiologyauthors
Tsugane S,Fahey MT,Sasaki S,Baba Sdoi
10.1093/oxfordjournals.aje.a009946subject
Has Abstractpub_date
1999-12-01 00:00:00pages
1201-7issue
11eissn
0002-9262issn
1476-6256journal_volume
150pub_type
杂志文章abstract：:To assess recall of childhood socioeconomic position for public health research, the authors conducted a cross-sectional study of 352 adult women twin pairs enrolled in Examination II of the Kaiser Permanente Women Twins Study carried out in 1989-1990 in Oakland, California. Among twin pairs, 91% (95% confidence inter...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a009512
更新日期：1998-04-01 00:00:00
abstract：:Racial and ethnic differences in associations between socioeconomic position (SEP) and risk of childhood acute lymphoblastic leukemia (ALL) were investigated using data from population-based cancer registries in the Surveillance, Epidemiology, and End Results Program in the United States. The study included 8,383 ALL ...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kww164
更新日期：2017-06-15 00:00:00
abstract：:Evaluation of adult health risks from exposures that occurred in childhood may require case-control studies in which subjects who are now adults are asked to provide information that might be more accurately provided by their parents. The quality of parental smoking and drinking histories provided by adult offspring w...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a114453
更新日期：1986-11-01 00:00:00
abstract：:The isolation of chlamydial trachomatis in sera of patients with gon ococcal urethritis (GU), non-gonococcal urethritis (NGU), post-gonococca l urethritis (PGU) and trachomainclusion conjunctivitis (TRIC) is discussed. Chlamydiae were isolated in 40% of men with NGU, 20-30% with GU and 0-7% of men with symptomatic or...
journal_title：American journal of epidemiology
pub_type： 杂志文章,评审
doi：10.1093/oxfordjournals.aje.a112243
更新日期：1976-05-01 00:00:00
abstract：:In this paper, the authors report on the design of a population-based case-control study of family history as a risk factor for coronary heart disease (CHD). They studied the characteristics of subjects who completed a detailed family history questionnaire in 1992-1994 as well as the accuracy of recall of family histo...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a009410
更新日期：1998-06-15 00:00:00
abstract：:In a case-control study, matching on a disease risk score (DRS), which includes many confounders, should theoretically result in greater precision than matching on only a few confounders; however, this has not been investigated. We simulated 1,000 hypothetical cohorts with a binary exposure, a time-to-event outcome, a...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwv269
更新日期：2016-05-15 00:00:00
abstract：:Leptin is an important regulator of the mass of adipose tissue and of body weight; it operates by inhibiting food intake and stimulating energy expenditure. Some polymorphic genes involved in the regulation of leptin-the leptin gene (LEP A19G), the leptin receptor gene (LEPR Q223R, K109R, and K656N), and the peroxisom...
journal_title：American journal of epidemiology
pub_type： 杂志文章,meta分析,评审
doi：10.1093/aje/kwi174
更新日期：2005-07-15 00:00:00
abstract：:During the period from September 8 to October 2, 1970, 44 of the 120 children and 78 of 141 adults questioned at the Children's Asthma Research Institute and Hospital experienced gastroenteritis characterized by nausea, vomiting, and fever and/or chills. Diarrhea was rare in children (4.5%) and common in adults (74%)....
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a112154
更新日期：1975-09-01 00:00:00
abstract：:An estimated 3.1 million children die each year because of undernutrition. Although cross-sectional and longitudinal studies have found a protective association between greater parental education and undernutrition in their children, no randomized trial has identified a causal effect, to our knowledge. Using the 1980 ...
journal_title：American journal of epidemiology
pub_type： 临床试验,杂志文章
doi：10.1093/aje/kwx195
更新日期：2018-01-01 00:00:00
abstract：:As a scientific discipline, epidemiology has helped liberate the practice of public health and medicine from dogmatic thinking over the past century. This commentary highlights some integrating principles to explain why epidemiology is a problem-solving discipline. The first of these is that epidemiology is an informa...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwn311
更新日期：2009-01-15 00:00:00
abstract：:Diabetes mellitus is a heterogeneous disease. The better classification of types of diabetes mellitus among adults will improve epidemiologic studies of determinants of risk factors and genetic host susceptibility. Recently, an antibody to a specific enzyme, glutamic acid decarboxylase, has been closely linked to insu...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a117316
更新日期：1994-10-15 00:00:00
abstract：:Prolonged sitting time is associated with several health outcomes; limited evidence indicates associations with frailty. Our aims in this study were to identify patterns of sitting time over 12 years in middle-aged (ages 50-55 years) women and examine associations of these patterns with frailty in older age. We examin...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwy111
更新日期：2018-11-01 00:00:00
abstract：:Retinal arteriolar narrowing is a marker of microvascular damage from elevated blood pressure. Between August 2004 and June 2006, the authors examined the association between retinal vascular diameter and chronic kidney disease in a population-based cohort of 3,280 community-dwelling adults of Malay ethnicity aged 40-...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwn367
更新日期：2009-03-01 00:00:00
abstract：:Maternal angiogenic factors (placental growth factor, soluble fms-like tyrosine kinase 1 (Flt-1), and soluble endoglin) may be associated with fetal growth restriction, and the associations may differ according to stage of pregnancy. Among children born to pregnant women without preeclampsia in Norway between 1992 and...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwq373
更新日期：2011-03-15 00:00:00
abstract：:In the period August 10-29, 1986, 29 confirmed cases of Legionnaires' disease occurred in Sheboygan, Wisconsin; two cases were fatal. No common source of indoor exposure was identified. Water specimens were obtained from all known cooling tower units in Sheboygan; Legionella pneumophila serogroup 1 was isolated at 1 x...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a115370
更新日期：1989-09-01 00:00:00
abstract：:Accurate measurement of central fat patterning is difficult to obtain by conventional anthropometry. Direct measurement of intra-abdominal fat area by magnetic resonance imaging, while accurate, is impractical for large-scale observational studies. This report examines the sex-specific associations of conventional ant...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a008934
更新日期：1996-08-15 00:00:00
abstract：:Observational studies and randomized controlled trials of menopausal hormone therapy (HT) and chronic disease risk appear to have divergent results for cardiovascular disease. However, differences may be related to a modifying effect of age, time since menopause, and HT formulation. In the Nurses' Health Study (NHS) (...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwx131
更新日期：2017-09-15 00:00:00
abstract：:A recent study of two communities in Massachusetts showed that a group of high school sophomores exposed to 107 mg/liter sodium in their municipal drinking water had significantly higher systolic and diastolic blood pressures than a control group exposed to 8 mg/liter. The present study was undertaken to determine if ...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a113252
更新日期：1981-12-01 00:00:00
abstract：:A case-control study of women with cervical abnormalities identified through Pap smears, was conducted in the Bronx, New York, to explore the relationship between nutritional intake and cervical dysplasia. Nutrient intake was estimated from computer analysis of three-day food records and 24-hour recall for 169 study p...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a113243
更新日期：1981-11-01 00:00:00
abstract：:There is growing interest in understanding how food environments affect diet, but characterizing the food environment is challenging. The authors investigated the relation between global diet measures (an empirically derived "fats and processed meats" (FPM) dietary pattern and the Alternate Healthy Eating Index (AHEI)...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwm394
更新日期：2008-04-15 00:00:00
abstract：:The aim of this study was to assess the accuracy and utility of administrative health data in identifying persons with inflammatory bowel disease on a population basis and to determine the incidence and prevalence of this disease in the Canadian province of Manitoba. The data from Manitoba Health (the province's singl...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a009735
更新日期：1999-05-15 00:00:00
abstract：:There is broad agreement that religion is a social determinant of health. In the article by Chen and VanderWeele (Am J Epidemiol. 2018;187(11):2355-2364), the authors took an outcome-wide approach to demonstrate associations between religious practices early in the life course (regular service attendance and prayer/me...
journal_title：American journal of epidemiology
pub_type： 评论,杂志文章
doi：10.1093/aje/kwz204
更新日期：2020-12-01 00:00:00
abstract：:Does a rise in crime result in increased sitting time and a reduction in physical activity? We used unobserved ("fixed")-effects models to examine associations between change in objectively measured crime (nondomestic violence, malicious damage, breaking and entering, and stealing, theft, and robbery) in Australia and...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kww106
更新日期：2016-12-15 00:00:00
abstract：:Several groups of variola isolates were compared in DNA structure, and by four independent biologic markers. Isolates of variola minor from Europe and South America (alastrim virus) could be distinguished from African isolates of variola minor by DNA structure and by two of the four biologic markers. Taken as a group,...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a114255
更新日期：1986-03-01 00:00:00
abstract：:To assess whether recent coffee consumption is related to the incidence of large bowel cancer, the authors analyzed data from a multipurpose hospital-based case-control study of several cancers, conducted from 1978 to 1986 in Boston, Massachusetts, New York, New York, Philadelphia, Pennsylvania, and Baltimore, Marylan...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a115422
更新日期：1989-11-01 00:00:00
abstract：:Case-control differences in prediagnostic serum levels of retinol, beta-carotene, vitamin E, and selenium are compared for 10 cancer sites in 10 study populations. For all four nutrients, the majority of results showed lower levels among persons who subsequently became cases than among controls. Low levels of beta-car...
journal_title：American journal of epidemiology
pub_type： 临床试验,杂志文章,多中心研究,评审
doi：10.1093/oxfordjournals.aje.a116264
更新日期：1992-01-15 00:00:00
abstract：:Efficient control of confounding is well recognized as a legitimate motive for restriction, matching, and conditional analysis in case-control studies. Some investigators, however, have advocated use of the same techniques for another purpose: to achieve a balance of "opportunity" or "potential" for past exposure betw...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a114244
更新日期：1986-02-01 00:00:00
abstract：:Agreement between frequency and quantitative dietary methods was assessed for the ability of frequency intake data to substitute for quantitative intake data in diet-disease investigations. Frequency and quantitative intakes of 342 male subjects participating in an ongoing case-control study in Hawaii during 1981-1982...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a113751
更新日期：1984-03-01 00:00:00
abstract：:Iron, potassium, zinc, and other minerals might impact the development of premenstrual syndrome (PMS) through multiple mechanisms, but few studies have evaluated these relations. We conducted a case-control study nested within the prospective Nurses' Health Study II (1991-2001). Participants were free from PMS at base...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kws363
更新日期：2013-05-15 00:00:00
abstract：:The authors report the results of the first 2 years of follow-up of a prospective cohort study on the mother-to-child transmission of human immunodeficiency virus type 1 (HIV-1) and its determinants which started in November 1988 in Kigali, Rwanda. The study sample consists of 218 newborns of 215 HIV-1 seropositive wo...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a116716
更新日期：1993-03-15 00:00:00
