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New pyrrole derivatives as antimycobacterial agents analogs of BM212.

Abstract：

:During the course of our investigations in the field of azole antimicrobial agents, we have identified BM212 a pyrrole derivative with good in vitro activity against mycobacteria and candidae. These findings prompted us to prepare new pyrrole derivatives 2-6 in the hope of increasing the activity. The microbiological data showed interesting in vitro activity against Mycobacterium tuberculosis and atypical mycobacteria.

journal_name

Bioorg Med Chem Lett

journal_title

Bioorganic & medicinal chemistry letters

authors

Biava M,Fioravanti R,Porretta GC,Deidda D,Maullu C,Pompei R

doi

10.1016/s0960-894x(99)00510-7

subject

Has Abstract

pub_date

1999-10-18 00:00:00

pages

2983-8

issue

20

eissn

0960-894X

issn

1464-3405

pii

S0960894X99005107

journal_volume

9

pub_type

杂志文章

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