Mild hypothermia on anoxic depolarization and subsequent cortical injury following transient ischemia.

abstract：INTRODUCTION:Alzheimer's disease (AD) is the most common neurodegenerative disease across the world. The major cause of AD is extensive oxidative stress and inflammation in central nervous system (CNS). Vitamin D3 and E are the most known vitamins that control oxidative stress and mitochondrial respiratory function. Th...

journal_title：Neurological research

authors： Mehrabadi S,Sadr SS

更新日期：2020-10-01 00:00:00

abstract：:Cyclic GMP (cGMP) mediates smooth muscle relaxation in the central nervous system. In subarachnoid hemorrhage (SAH), decreases in intrinsic nitric oxide (NO) cause cerebral vasospasms due to the regulation of cGMP formation by NO-mediated pathways. As phosphodiesterase type V (PDE V) selectively hydrolyzes cGMP, we hy...

journal_title：Neurological research

authors： Inoha S,Inamura T,Ikezaki K,Nakamizo A,Amano T,Fukui M

更新日期：2002-09-01 00:00:00

abstract：:Endolymphatic sac tumors are rare, low-grade adenocarcinomas of the petrous bone. These tumors are highly vascularized and surgical removal is often challenging. We present a staged endovascular-neurosurgical approach consisting of stent-assisted angioplasty of the petrous carotid, selective endovascular embolization ...

journal_title：Neurological research

authors： Cohen JE,Spektor S,Valarezo J,Fellig Y,Umansky F

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND:Neurocysticercosis is a parasitic infection of the central nervous system caused by the larval stage of the tapeworm Taenia solium and is the most common parasitic infection involving the human nervous system. Neurocysticercosis represents one of the most common causes of symptomatic epilepsy in developing c...

journal_title：Neurological research

authors： Ramírez-Zamora A,Alarcón T

更新日期：2010-04-01 00:00:00

abstract：:In order to investigate the role of the endothelium in the regulation of cerebrovascular tone, we studied selective intraluminal and extraluminal vasoactive mechanisms of acetylcholine, potassium and serotonin. We also examined the effects of removal of the endothelium on these vasoactive responses. With 0.75 g of ten...

journal_title：Neurological research

authors： Ogawa R,Ohta T,Tsuji M,Mori M

更新日期：1993-06-01 00:00:00

abstract：:Cerebral aneurysms are composed principally of collagen, a birefringent protein which is responsible for withstanding the forces of blood pressure. The known correlation between collagen birefringence and its mechanics provides the basis for using polarizing microscopy to evaluate the strength of collagen, layer by la...

journal_title：Neurological research

authors： Canham PB,Finlay HM,Kiernan JA,Ferguson GG

更新日期：1999-10-01 00:00:00

abstract：OBJECTIVE:The actual relationship between neural stem cells and SDF-1alpha/CXCR4 after brain injury has not yet been elucidated, although recent studies have speculated that stromal cell-derived factor-1alpha (SDF-1alpha) and its receptor, CXCR4, could contribute to neural stem cells migration after brain injury. In th...

journal_title：Neurological research

authors： Itoh T,Satou T,Ishida H,Nishida S,Tsubaki M,Hashimoto S,Ito H

更新日期：2009-02-01 00:00:00

abstract：:The frequency of skull metastasis from hepatocellular carcinoma (HCC) is increasing together with the recent progress in the management of the primary lesion. Cases are often complicated with poor general conditions or metastasis to the other organs, and not readily indicated for surgery. A direct injection of ethanol...

journal_title：Neurological research

authors： Isaka T,Yoshimine T,Fujimoto K,Masuzawa M,Maruno M,Hayakawa T,Nakatani S

更新日期：1998-12-01 00:00:00

abstract：:Aspirin and ticlopidine are two commonly used drugs in the prevention of cerebral embolic ischemic events. No direct comparisons in a cross-over design of the effects of ticlopidine and aspirin on asymptomatic circulating cerebral microemboli are available. We investigated 53 patients with cerebrovascular disease. Twe...

journal_title：Neurological research

authors： Droste DW,Sonne M,Siemens HJ,Kaps M

更新日期：1996-10-01 00:00:00

abstract：OBJECTIVE:To explore the primary regularity of cerebral electrical impedance (CEI) change in healthy people, patients with intracerebral hemorrhage (ICH) and patients with cerebral infarction (CI). METHODS:CEI of 200 healthy volunteers, 78 patients with ICH and 51 patients with CI were measured by noninvasive brain-ed...

journal_title：Neurological research

authors： Liu L,Dong W,Ji X,Chen L,Chen L,He W,Jia J

更新日期：2006-01-01 00:00:00

abstract：:Decreased metabolic rate may precede cognitive impairment in Alzheimer's disease (AD) and is thus an early occurring hallmark. Several observations in post-mortem brain indicate that activated neurons are better able to withstand aging and AD, a phenomenon paraphrased by us as 'use it or lose it'. Moreover, a number o...

journal_title：Neurological research

authors： Swaab DF

更新日期：2003-09-01 00:00:00

abstract：OBJECTIVES:The stroke-prone spontaneously hypertensive rat is a genetic model of severe hypertension with secondary vascular alterations. The aim of this study was to determine the influence of chronic hypertension and ramipril treatment on the extracellular matrix in the cerebral microvasculature. METHODS:The study c...

journal_title：Neurological research

authors： Liebetrau M,Burggraf D,Büscher C,Linz W,Hamann GF

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVE:To review past, present and future applications of near-infrared spectroscopy (NIRS) in clinical neuroscience. METHODS:The literature and personal experience of the authors were critically reviewed in order to provide a balanced overview of the basic principles, clinical validation, previous experience and c...

journal_title：Neurological research

authors： Calderon-Arnulphi M,Alaraj A,Slavin KV

更新日期：2009-07-01 00:00:00

abstract：:Before extending the application of motor cortex stimulation it is important to investigate the intimate mechanisms by which it alleviates intractable pain and to consider possible side effects. Self-mutilation in animals following extensive neurectomy or posterior rhizotomy of a limb is thought to reveal severe dyses...

journal_title：Neurological research

authors： Pioli EY,Gross CE,Meissner W,Bioulac BH,Bezard E

更新日期：2003-03-01 00:00:00

abstract：OBJECTIVES:The purpose of this study is to use diffusion tensor imaging (DTI) parameters to evaluate cerebral ischemia/reperfusion injury in the infarct core (IC) and ischemic penumbra (IP) in a rhesus transient middle cerebral artery occlusion (MCAO) model. METHODS:Seven rhesus monkeys were used to construct the MCAO...

journal_title：Neurological research

authors： Guo J,Zheng HB,Duan JC,He L,Chen N,Gong QY,Tang HH,Li HX,Wang L,Cheng JQ

更新日期：2011-01-01 00:00:00

abstract：:Sinus pericranii is a rare circumscribed fluctuating vascular swelling of the scalp that communicates with the intracranial venous system. It has been associated with other intracranial vascular malformations. The tumour is usually round, fluctuant, nonpulsatile, and disappears with compression. Its size increases dur...

journal_title：Neurological research

authors： Vinas FC,Valenzuela S,Zuleta A

更新日期：1994-12-01 00:00:00

abstract：:Ninety percent of cerebral aneurysms were diagnosed after their first rupture with consecutive subarachnoid haemorrhage. In order to detect the aneurysms before rupture investigation by transcranial Doppler sonography was used on the basis of intra-operative evaluation of the normal aneurysmal flow pattern. In 34 pati...

journal_title：Neurological research

authors： Gilsbach JM,Harders AG

更新日期：1989-03-01 00:00:00

abstract：:Fifteen patients with symptoms of cerebral ischaemia and angiographically confirmed unilateral stenoses or occlusions of the extracranial internal carotid artery (ICA) and 20 controls were studied by a 2 MHz transcranial Doppler (TCD) at rest and after stimulation with 1 g acetazolamide i.v., a cerebral vasodilator. I...

journal_title：Neurological research

authors： Rosenkranz K,Hierholzer J,Langer R,Hepp W,Palenker J,Felix R

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVE:A reproducible brain tumor model using experimental animals is required to study biological behavior and develop more potent antineoplastic drugs and effective therapeutic modalities. In this work, we attempted to establish diffuse leptomeningeal gliomatosis in the rat by intracarotid injection of C6 glioma c...

journal_title：Neurological research

authors： Wasita B,Kamitani H,Kinoshita Y,Mamun MH,Watanabe T

更新日期：2009-06-01 00:00:00

abstract：:This study comprises scientific-theoretic fundamental investigations of laserneedle technology, a new and painless method of acupuncture stimulation. Laserneedles are not inserted in the skin, but are merely placed on the surface of the acupuncture point. The study documents the significant changes in peripheral micro...

journal_title：Neurological research

authors： Litscher G

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVES:Intracranial aneurysms (IAs) of the posterior circulation (PC) rupture more frequently and their morbidity and mortality rates are higher compared to anterior circulation. Morphological parameters such as size ratio (SR), inflow angle and parent artery geometry are believed to contribute significantly in det...

journal_title：Neurological research

authors： Tykocki T,Nauman P,Dow Enko A

更新日期：2014-08-01 00:00:00

abstract：:We describe a case of rebleeding from an intracranial vertebral dissecting aneurysm following proximal clipping. This case suggests that proximal clipping alone may not be an adequate surgical procedure to prevent rebleeding. Surgical treatment of intracranial dissecting aneurysms in the vertebral artery presenting as...

journal_title：Neurological research

authors： Kawamata T,Tanikawa T,Takeshita M,Onda H,Takakura K,Toyoda C

更新日期：1994-04-01 00:00:00

abstract：:We examined whether or not NF-kappaB, a factor that regulates expression of the genes that code for pro-inflammatory cytokines, is activated in cerebrospinal fluid (CSF) cells to investigate the production of pro-inflammatory cytokines by CSF cells in patients with meningitis. Western blotting demonstrated that NF-kap...

journal_title：Neurological research

authors： Ichiyama T,Isumi H,Yoshitomi T,Nishikawa M,Matsubara T,Furukawa S

更新日期：2002-10-01 00:00:00

abstract：:The therapeutic effect of insulin alone or insulin combined with 30 min delayed thrombolytic therapy was investigated in rats embolized in the right hemisphere with a fibrin clot made from autologous blood. Animals were killed seven days after embolization and the infarct volumes were measured in % of the affected hem...

journal_title：Neurological research

authors： Meden P,Andersen M,Overgaard K,Rasmussen RS,Boysen G

更新日期：2002-06-01 00:00:00

abstract：OBJECTIVE:Transcranial Doppler (TCD) measures blood flow velocities (BFV) and is an indirect method of assessing cerebral blood flow (CBF). Positron emission tomography (PET) is a direct method to measure CBF. This study evaluates the correlations between TCD and PET findings Methods: Nine patients with a symptomatic c...

journal_title：Neurological research

authors： Rijbroek A,Boellaard R,Vriens EM,Lammertsma AA,Rauwerda JA

更新日期：2009-02-01 00:00:00

abstract：:Objective: The protective effects of 2%-4% hydrogen gas in delayed encephalopathy after acute carbon monoxide poisoning (DEACMP) have been previously reported. This study aimed to assess the neuroprotective effects of high concentration hydrogen (HCH) on DEACMP.Methods: A total of 36 male Sprague-Dawley rats were divi...

journal_title：Neurological research

authors： Shen M,Zheng Y,Zhu K,Cai Z,Liu W,Sun X,Liu J,Zhu D

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVES:To assess prospectively the significance of sonographic measurements of the median nerve in the diagnosis of carpal tunnel syndrome (CTS), to look for proper parameters and cutoff values for the sonographic diagnosis, and to correlate with the electrophysiological findings. MATERIALS AND METHODS:This study ...

journal_title：Neurological research

authors： Guan J,Ji F,Chen W,Chu H,Lu Z

更新日期：2011-11-01 00:00:00

abstract：:This paper reviews our recent studies of the role of cortical spreading depression (CSD) in the pathogenesis of brain disorders. Our investigation is a computational one, involving the development and utilization of a complex neuro-metabolic model of the interactions assumed to occur in the cortex during the passage o...

journal_title：Neurological research

authors： Ruppin E,Reggia JA

更新日期：2001-07-01 00:00:00

abstract：:We examined regional cerebral blood flow (rCBF) and oxygen metabolism (rCMRO2) in 10 patients with progressive dementia and amyotrophic lateral sclerosis (DALS), in 21 patients with classical amyotrophic lateral sclerosis without dementia (ALS), and in 17 controls. The mean rCBF and rCMRO2, especially in the anterior ...

journal_title：Neurological research

authors： Tanaka M,Ichiba T,Kondo S,Hirai S,Okamoto K

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:Hemorrhagic transformation (HT) is a common complication of ischemic stroke. We performed this study to determine whether aspartate aminotransferase (AST) to alanine aminotransferase (ALT) ratio (AAR) was related to HT, as well as compare the predictive values of AAR, ALT and AST for HT in patients with isch...

journal_title：Neurological research

authors： Wang Y,Qiu K,Song Q,Cheng Y,Liu J,Liu M

更新日期：2020-11-01 00:00:00