corticofugal regulation of excitatory and inhibitory frequency tuning curves of bat inferior collicular neurons.

abstract：:Dorsal temporal pole (dTP) is a cortical region at the rostral end of the superior temporal gyrus that forms part of the ventral auditory object processing pathway. Anatomical connections with frontal and medial temporal areas, as well as a recent single-unit recording study, suggest this area may be an important part...

journal_title：Brain research

authors： Bigelow J,Ng CW,Poremba A

更新日期：2016-06-01 00:00:00

abstract：:Nasal and temporal microexplants from the retina of the chicken embryo (E6; White Leghorn) were cultured on a collagen gel in the presence of extract from anterior or posterior E18 optic tectum. After 4 days of incubation maximum neurite lengths were measured as a function of protein concentration (1-500 micrograms/ml...

journal_title：Brain research

authors： Carri NG,Ebendal T

更新日期：1987-01-01 00:00:00

abstract：:The effects of the sulfated octapeptide of cholecystokinin (CCK8-S), the non-sulfated homolog (CCK8-NS) as well as the C-terminal di-, tri- and tetrapeptidic fragments (respectively CCK2, CCK3 and CCK4) were studied in vitro in rat hippocampal slices by extracellular recording of the spontaneous action potential disch...

journal_title：Brain research

authors： Böhme GA,Stutzmann JM,Blanchard JC

更新日期：1988-06-07 00:00:00

abstract：:In situ hybridization (ISH) is an essential technique for mapping gene expression in the brain. Although many ISH protocols provide for quantitative analysis of individual mRNAs in different brain regions or across experimental conditions, this technique has lacked the necessary standardization for quantitative compar...

journal_title：Brain research

authors： Broide RS,Trembleau A,Ellison JA,Cooper J,Lo D,Young WG,Morrison JH,Bloom FE

更新日期：2004-03-12 00:00:00

abstract：:In this paper the response of cerebral phosphate metabolism to mild hypoxia in young, medium and old rats has been studied via in-vivo [31P]nuclear magnetic resonance (NMR). It was found that the young adults (5-6 months) were more sensitive to this mild stress than either the mature adult (11-12 months) or senescent ...

journal_title：Brain research

authors： Stolk JA,Olsen JI,Reeves PM,Chen M,Perry C,Alderman DW,Lee YC,Schweizer MP

更新日期：1989-03-13 00:00:00

abstract：:Levodopa (L-DOPA) is widely used for symptomatic management in Parkinson's disease. We recently showed that (-)-epigallocatechin-3-gallate, a tea polyphenol, not only inhibits L-DOPA methylation, but also protects against oxidative hippocampal neurodegeneration. In the present study, we sought to determine several oth...

journal_title：Brain research

authors： Kang KS,Yamabe N,Wen Y,Fukui M,Zhu BT

更新日期：2013-02-25 00:00:00

abstract：:Rats were trained on a radial maze and then given electrolytic lesions of the MS followed by a single intraseptal injection of 5 micrograms of NGF. Three days later they were re-tested on the maze. They were also post-operatively tested for hyperemotionality. MS lesions severely impaired performance on the radial maze...

journal_title：Brain research

authors： Janis LS,Glasier MM,Martin G,Stackman RW,Walsh TJ,Stein DG

更新日期：1995-05-08 00:00:00

abstract：:We have previously raised a monoclonal antibody (69A1) which recognises a cell-surface antigen expressed on rat cerebellar neurons both in culture and in tissue sections of the developing cerebellum prior to postnatal day 17. In our current study we have undertaken a detailed analysis of the loss of labelling from the...

journal_title：Brain research

authors： Pigott R,Kelly JS

更新日期：1986-09-01 00:00:00

abstract：:Conflicting results concerning the issue of whether or not chronic morphine exposure induces an increase in CCK biosynthesis have been found in many CNS sites, including the spinal cord, where CCK activity may contribute to the facilitation of the development of opiate tolerance. The present study was undertaken in or...

journal_title：Brain research

authors： Lucas GA,Hoffmann O,Alster P,Wiesenfeld-Hallin Z

更新日期：1999-03-06 00:00:00

abstract：:Preferential uptake of dopamine occurred in mesocortical vs striatal synaptosomes obtained from acutely fighting isolated male ICR mice. Specifically, both Km and Vmax were significantly increased in the prefrontal cortex but not the caudate-putamen. The findings are similar to selective changes in mesocortical activi...

journal_title：Brain research

authors： Hadfield MG

更新日期：1981-10-05 00:00:00

abstract：:The existence of multiple brain melanocortin receptor types has been postulated, based on the complex pharmacology of intracerebrally administered melanocortin (melanocyte-stimulating hormone-related) peptides. In this study, this hypothesis was tested by determining whether different brain melanocortin receptor popul...

journal_title：Brain research

authors： Tatro JB,Entwistle ML

更新日期：1994-01-28 00:00:00

abstract：:Frequency-current curves for CA1 hippocampal pyramidal neurons are shown to have basically the same shape as those for spinal motoneurones, with a region of shallow slope at low frequencies, preceding a sleep linear or upward convex region at higher frequencies. The frequency range is, however, displaced towards lower...

journal_title：Brain research

authors： Gustafsson B,Wigström H

更新日期：1981-11-02 00:00:00

abstract：UNLABELLED:This study examines the effects of progesterone on blood-brain barrier (BBB) integrity following thrombin administration. Thrombin is expressed in many diseases which affect neural tissue and is associated with breakdown of the BBB. Progesterone has shown protective effects on the BBB in stroke and traumatic...

journal_title：Brain research

authors： Hun Lee J,Won S,Stein DG

更新日期：2015-07-10 00:00:00

abstract：:To determine the involvement of vasoactive intestinal polypeptide (VIP) in the development of kindling in rats, VIP or antibody to VIP (anti-VIP) was injected into the third ventricle after the daily stimulation of the basolateral amygdala. The number of stimulations required to reach full amygdaloid kindling was sign...

journal_title：Brain research

authors： Funabashi T,Hiruma H,Arita J,Kimura F

更新日期：1991-02-08 00:00:00

abstract：:Propofol is an intravenous anesthetic with neuroprotective effects against cerebral ischemia-reperfusion (I/R) injury. Few studies regarding the neuroprotective and neurobehavioral effects of propofol have been conducted, and the underlying mechanisms are still unclear. Because I/R may result in neuronal apoptosis, th...

journal_title：Brain research

authors： Xi HJ,Zhang TH,Tao T,Song CY,Lu SJ,Cui XG,Yue ZY

更新日期：2011-09-02 00:00:00

abstract：:Excitotoxic neuronal death underlies many neurodegenerative disorders. Because cannabinoid receptor agonists act presynaptically to inhibit glutamate release, we examined the effects of Win 55212-2, a full agonist at CB(1) receptors, and Delta(9)-tetrahydrocannabinol (THC), a partial agonist, on the survival of neuron...

journal_title：Brain research

authors： Gilbert GL,Kim HJ,Waataja JJ,Thayer SA

更新日期：2007-01-12 00:00:00

abstract：:The pattern of generation of neurons in the albino rat superior colliculus has been studied in adult and fetal material. Neurons are generated between embryonic days 12 to 17, with rostrolateral colliculus in advance of caudomedial parts. More of the cells contributing to the deeper layers are generated early, while m...

journal_title：Brain research

authors： Mustari MJ,Lund RD,Graubard K

更新日期：1979-03-23 00:00:00

abstract：:The motivational effects of exclusively peripheral or central opiate receptor blockade were studied using place conditioning. Place aversions were observed with intraventricular (i.c.v.) methylnaloxone (MN) in both naive (200-1000 ng) and morphine-dependent rats (50-500 ng). Subcutaneous MN (0.03-10 mg/kg) was ineffec...

journal_title：Brain research

authors： Hand TH,Koob GF,Stinus L,Le Moal M

更新日期：1988-12-06 00:00:00

abstract：:Sustained neuroinflammation contributes to the pathogenesis of postoperative cognitive dysfunction. Dexmedetomidine, a selective α-2 adrenergic receptor agonist, exhibits a protective role in the brain. This study investigated whether dexmedetomidine pretreatment attenuates neuroinflammation induced by tibial fracture...

journal_title：Brain research

authors： Zhu YJ,Peng K,Meng XW,Ji FH

更新日期：2016-08-01 00:00:00

abstract：:In vitro assays offer a means of screening potential therapeutics and accelerating the drug development process. Here, we utilized neuronal cultures on planar microelectrode arrays (MEA) as a functional assay to assess the neurotoxicity of amyloid-β 1-42 (Aβ42), a biomolecule implicated in the Alzheimer׳s disease (AD)...

journal_title：Brain research

authors： Charkhkar H,Meyyappan S,Matveeva E,Moll JR,McHail DG,Peixoto N,Cliff RO,Pancrazio JJ

更新日期：2015-12-10 00:00:00

abstract：:An in vitro radioenzymatic assay and purification procedure by thin-layer chromatography were used to study the metabolism of dihydrotestosterone (DHT) into 3 alpha- and 3 beta-androstanediols by the brain and cloacal gland of Japanese quail. Kinetic studies showed that these 2 metabolites are produced in a linear fas...

journal_title：Brain research

authors： Deviche P,Delville Y,Balthazart J

更新日期：1987-09-22 00:00:00

abstract：:The effects of selective dopamine D1 (SKF 38393) and D2 (4-propyl-9-hydroxynaphthoxazine or PHNO) agonists on free-running rhythms of locomotor activity in rats were investigated under either constant light (LL) or dark (DD) condition. Rats under the DD condition exhibited clear circadian patterns of activity, while c...

journal_title：Brain research

authors： Yamada N,Martin-Iverson MT

更新日期：1991-01-11 00:00:00

abstract：:The formation of reactive oxygen species (ROS) has been suggested to be associated with excitotoxicity but the involvement of cytoplasmic enzymes in ROS formation is not clearly known. In the present study, we examined the role of xanthine oxidase (XO), nitric oxide synthase (NOS) and phospholipase A(2) (PLA(2)) in gl...

journal_title：Brain research

authors： Sanganahalli BG,Joshi PG,Joshi NB

更新日期：2005-03-10 00:00:00

abstract：:The present study was undertaken to investigate and compare the properties of noradrenaline release in the locus coeruleus (LC) and prefrontal cortex (PFC). For that aim the dual-probe microdialysis technique was applied for simultaneous detection of noradrenaline levels in the LC and PFC in conscious rats. Calcium om...

journal_title：Brain research

authors： Pudovkina OL,Kawahara Y,de Vries J,Westerink BH

更新日期：2001-07-06 00:00:00

abstract：:Individuals are found to have better recall for self-referent information than other types of information. However, attribution research has shown that self-reference is highly correlated with emotional valence. The present study attempted to identify and separate the processing of self-reference and emotional valence...

journal_title：Brain research

authors： Watson LA,Dritschel B,Obonsawin MC,Jentzsch I

更新日期：2007-06-04 00:00:00

abstract：:The effect of arginine vasopressin (AVP) on protein phosphorylation in rat hippocampal synaptic plasma membranes (SPM) was examined. With a crude SPM preparation, AVP (10(-8)-10(-5) M) stimulated phosphorylation of a number of proteins which included a brain-specific protein of 48 kDa called B50 or protein F1, which i...

journal_title：Brain research

authors： Hinko A,Kim Y,Pearlmutter AF

更新日期：1986-10-01 00:00:00

abstract：:Acute administration of diazepam (2 mg/kg i.p.) to rats decreased the number of head-dips, locomotor activity and the number of rears made in the holeboard apparatus, indicating sedative effects. After daily treatment for 7 days with diazepam (2 mg/kg) tolerance developed to all these behavioural effects, despite seru...

journal_title：Brain research

authors： Fernandes C,File SE,Berry D

更新日期：1996-09-23 00:00:00

abstract：:Recent evidence suggests that the primary visual cortex (V1) of rodents expresses surprisingly high levels of plasticity into adulthood. For example, long-term potentiation (LTP) is readily induced in the mature V1 of adult rodents in vivo. Here, adult, urethane-anesthetized rats were used for a detailed characterizat...

journal_title：Brain research

authors： Kuo MC,Dringenberg HC

更新日期：2012-12-07 00:00:00

abstract：:uinea pig antiserum specific to the purified bovine choline acetyltransferase was used to demonstrate the localization of this enzyme in rabbit forebrain by the peroxidase-antiperoxidase immunohistochemical method. Choline acetyltransferase was localized in olfactory bulb, olfactory tract, olfactory tubercle, piriform...

journal_title：Brain research

authors： Chao LP,Kan KS,Hung FM

更新日期：1982-03-04 00:00:00

abstract：:One of the fundamental tasks of neurobiology is to understand how the precision and specificity of the adult nervous system is achieved during development. This paper reviews the progress that has been made toward this end in studies of the developing mammalian cerebral cortex. Particular attention is focused on the p...

journal_title：Brain research

authors： McConnell SK

更新日期：1988-01-01 00:00:00