The role of endoscopy in acute recurrent and chronic pancreatitis and pancreatic cancer.

abstract：:Radionuclide studies of the upper gastrointestinal tract have been useful in many gastrointestinal disorders. However, the literature relating to radionuclide techniques in morbid obesity is limited and, at times, controversial. It is hoped that this brief review will stimulate interest in the use of tracer techniques...

journal_title：Gastroenterology clinics of North America

authors： DeRogatis AJ

更新日期：1987-06-01 00:00:00

abstract：:Chronic pelvic pain is pain lasting longer than 6 months and is estimated to occur in 15% of women. Causes of pelvic pain include disorders of gynecologic, urologic, gastroenterologic, and musculoskeletal systems. The multidisciplinary nature of chronic pelvic pain may complicate diagnosis and treatment. Treatments va...

journal_title：Gastroenterology clinics of North America

authors： Stein SL

更新日期：2013-12-01 00:00:00

abstract：:In patients with Crohn's disease on biologic medications, the use of therapeutic drug monitoring leads to a personalized approach to optimize treatment. Using an algorithmic approach, measurement of drug concentrations and anti-drug antibodies can be used to improve treatment outcomes. Therapeutic drug concentrations ...

journal_title：Gastroenterology clinics of North America

authors： Heron V,Afif W

更新日期：2017-09-01 00:00:00

abstract：:Endoscopic retrograde cholangiopancreatography is an effective platform for a variety of therapies in the management of benign and malignant disease of the pancreas. Over the last 50 years, endotherapy has evolved into the first-line therapy in the majority of acute and chronic inflammatory diseases of the pancreas. A...

journal_title：Gastroenterology clinics of North America

authors： Riff BP,Chandrasekhara V

更新日期：2016-03-01 00:00:00

abstract：:Adenomatous polyps are the benign precursors of colorectal adenocarcinoma. Colonic adenomas occur commonly in adults in Western countries. There is recent evidence that inheritance may play an important role in the etiology of these adenomatous polyps. Colonic adenomatous polyposis (numerous colonic adenomas) is the c...

journal_title：Gastroenterology clinics of North America

authors： Burt RW,Samowitz WS

更新日期：1988-12-01 00:00:00

abstract：:Studies of ontogenesis contribute to better understanding of regulatory events underlying the striking heterogeneity in B-cell differentiation pathways employed in the human mucosal immune system. This disparity is probably explained by exogenous environmental factors, although regional differences probably also exist...

journal_title：Gastroenterology clinics of North America

authors： Brandtzaeg P,Nilssen DE,Rognum TO,Thrane PS

更新日期：1991-09-01 00:00:00

abstract：:If one reviews the literature with zeal, it is increasingly apparent that few organs escape recruitment when IBD is chronic or progressive. Insights into mucosal pathophysiology have helped with understanding the more frequent extraintestinal manifestations, but the mechanisms attendant to the development of less comm...

journal_title：Gastroenterology clinics of North America

authors： Levine JB,Lukawski-Trubish D

更新日期：1995-09-01 00:00:00

abstract：:Numerous extraintestinal diseases have been associated with IBD. The role of the gastrointestinal tract in host response to the foreign antigens present in the gut makes the enteric immune system highly susceptible to any external perturbation to the system. Dysregulation of the enteric immune response results in path...

journal_title：Gastroenterology clinics of North America

authors： Su CG,Judge TA,Lichtenstein GR

更新日期：2002-03-01 00:00:00

abstract：:The view of surgical treatment of esophageal carcinoma is pessimistic. This is so because (1) most patients present late in the disease and are beyond the benefits of surgical therapy for cure, (2) resection is associated with a high operative mortality, and (3) the poor 5-year survival rates for surgical resection ci...

journal_title：Gastroenterology clinics of North America

authors： Bremner RM,DeMeester TR

更新日期：1991-12-01 00:00:00

abstract：:Several hepatobiliary diseases appear to be mediated by the host immune response. They can be subdivided into those in which the immune reaction is against an infectious agent such as hepatitis viruses, those in which the immune reaction appears to be against an autoantigen expressed on hepatobiliary cells, and those ...

journal_title：Gastroenterology clinics of North America

authors： Vierling JM

更新日期：1992-06-01 00:00:00

abstract：:Pediatric patients with inflammatory bowel disease (IBD) stand to benefit from quality improvement (QI) due to the chronic nature of the disease, frequent interaction with the health care system, and exposure to high-risk treatments. The use of QI in health care has led to significant improvements in quality and relia...

journal_title：Gastroenterology clinics of North America

authors： Egberg MD,Kappelman MD,Gulati AS

更新日期：2018-12-01 00:00:00

abstract：:Women have started to enter gastroenterology (GI) in significant numbers over the past 5 years, although they are still underrepresented compared with the proportion of female graduating medical students. This underrepresentation is most likely caused by the culture of GI where female students and residents have felt ...

journal_title：Gastroenterology clinics of North America

authors： Elta GH

更新日期：2011-06-01 00:00:00

abstract：:Because there are no reliable biological or laboratory markers associated with the condition, the diagnosis of irritable bowel syndrome(IBS) is based on patient descriptions of common symptoms such as abdominal pain accompanied by changes in stool form or frequency and associated symptoms such as bloating and distensi...

journal_title：Gastroenterology clinics of North America

authors： Cash BD,Chey WD

更新日期：2005-06-01 00:00:00

abstract：:Radiation therapy is a rapidly evolving field, and recent technical advances have spurred an increasing number of new treatments as well as marked improvements in previously existing treatments. Despite a growing body of published evidence demonstrating that radiotherapy for the treatment of pancreatic cancer is impro...

journal_title：Gastroenterology clinics of North America

authors： Trakul N,Koong AC,Maxim PG,Chang DT

更新日期：2012-03-01 00:00:00

abstract：:CD and UC represent a spectrum of chronic IBD that present in protean ways and are accompanied by a variety of systemic sequelae. Sulfasalazine and the newer 5-aminosalicylates are important in the management of mild-to-moderate disease, whereas corticosteroids remain the primary therapy for most patients with moderat...

journal_title：Gastroenterology clinics of North America

authors： Stein RB,Hanauer SB

更新日期：1999-06-01 00:00:00

abstract：:Living donor intestinal transplantation (LDIT) has been improved leading to results comparable to those obtained with deceased donors. LDIT should be limited to specific indications and patient selection. The best indication is combined living donor intestinal/liver transplantation in pediatric recipients with intesti...

journal_title：Gastroenterology clinics of North America

authors： Tzvetanov IG,Tulla KA,D'Amico G,Benedetti E

更新日期：2018-06-01 00:00:00

abstract：:Esophageal high-resolution manometry (HRM) improves the management of patients with nonobstructive dysphagia. It has increased the diagnostic yield for detecting achalasia and defined three clinically relevant achalasia subtypes. Esophagogastric junction (EGJ) outflow obstruction, defined as an impaired EGJ relaxation...

journal_title：Gastroenterology clinics of North America

authors： Roman S,Kahrilas PJ

更新日期：2011-12-01 00:00:00

abstract：:Hepatic angiosarcoma is the second most common primary malignant neoplasm of the liver. Although comprising only 2 per cent of all hepatic primary tumors, it represents a major clinical problem because of its strong association with industrial vinyl chloride exposure and its incurability. Strict ceilings on the amount...

journal_title：Gastroenterology clinics of North America

authors： Weinman MD,Chopra S

更新日期：1987-12-01 00:00:00

abstract：:Overall, fecal markers have been found to be more accurate than serum markers. However, fecal markers are not specific for IBD and may be elevated in a range of organic conditions. Fecal calprotectin and lactoferrin can still differentiate inflammatory disease from functional bowel disorders. Comparison studies have f...

journal_title：Gastroenterology clinics of North America

authors： Abraham BP,Kane S

更新日期：2012-06-01 00:00:00

abstract：:Obesity-related disorders derive from a combination of genetic susceptibility and environmental factors. Recent evidence supports the role of gut microbiota in the pathogenesis of obesity, type 2 diabetes mellitus, and insulin resistance by increasing energy harvest from diet and by inducing chronic, low-grade inflamm...

journal_title：Gastroenterology clinics of North America

authors： Molinaro F,Paschetta E,Cassader M,Gambino R,Musso G

更新日期：2012-12-01 00:00:00

abstract：:There is sparse information regarding exercise and inflammatory bowel disease (IBD). Furthermore, the importance of regular exercise in the optimal management of IBD has not received attention in guidelines and is often overlooked by practitioners. This article summarizes evidence regarding health benefits of exercise...

journal_title：Gastroenterology clinics of North America

authors： Hashash JG,Binion DG

更新日期：2017-12-01 00:00:00

abstract：:Corticosteroids are of proven value for the treatment of active ulcerative colitis and Crohn's disease, but are of little value for the maintenance of remission. The development of new steroid compounds with low systemic bioavailability should allow higher doses to be given for longer periods without risking serious a...

journal_title：Gastroenterology clinics of North America

authors： Jewell DP

更新日期：1989-03-01 00:00:00

abstract：:Fecal incontinence affects up to 20% of community-dwelling adults and more than 50% of nursing home residents, and is one of the major risk factors for elderly persons in the nursing home. Institutionalization itself is a risk factor (eg, immobility due to physical restraints). Management should focus on identifying a...

journal_title：Gastroenterology clinics of North America

authors： Leung FW,Rao SS

更新日期：2009-09-01 00:00:00

abstract：:Lymphocyte homing antagonists represent promising therapeutic agents for the treatment of idiopathic inflammatory bowel disease (IBD). Several critical molecules involved in the recruitment of inflammatory cells in the intestine, including integrins and chemokine receptors, have been successfully targeted for the trea...

journal_title：Gastroenterology clinics of North America

authors： Saruta M,Papadakis KA

更新日期：2014-09-01 00:00:00

abstract：:Gastric cancer (GC) is third leading cause of cancer-related death. Only 28.3% of new GC cases survive more than 5 years. Although incidence has declined in the United States, an increase is estimated for 2016. Risk factors include sex (risk is higher in men), Helicobacter pylori infection, heredity, and lifestyle. GC...

journal_title：Gastroenterology clinics of North America

authors： Marqués-Lespier JM,González-Pons M,Cruz-Correa M

更新日期：2016-09-01 00:00:00

abstract：:Celiac disease is a common immune-mediated disorder that occurs in individuals with permissive genetics (HLA-DQ2/DQ8 genotype) following exposure to certain wheat proteins. The histopathologic manifestations of small intestinal mucosal injury (villus atrophy, crypt hyperplasia, and intraepithelial lymphocytosis) are w...

journal_title：Gastroenterology clinics of North America

authors： Lagana SM,Bhagat G

更新日期：2019-03-01 00:00:00

abstract：:Gastroesophageal reflux disease (GERD) is defined by either subjective complaints indicative of problematic gastroesophageal reflux or objective complications directly attributable to reflux. Studies focused on GERD-related symptoms suggest a worldwide increase in prevalence of approximately 4% per year. Epidemiologic...

journal_title：Gastroenterology clinics of North America

authors： Pandolfino JE,Kwiatek MA,Kahrilas PJ

更新日期：2008-12-01 00:00:00

abstract：:Because functional bowel disorders have no reliable markers, they must be defined by their symptoms. The various constellations of symptoms (syndromes) may have different mechanisms, differential diagnoses, and treatments. Therefore, precise classification is important on clinical and scientific grounds. Functional bo...

journal_title：Gastroenterology clinics of North America

authors： Thompson WG

更新日期：1991-06-01 00:00:00

abstract：:In conclusion, H. pylori infection can be detected by a variety of methods. The simplest, least expensive noninvasive method is serologic testing. Unfortunately, positive serology can only presume current infection. Urea breath testing is also noninvasive and is positive only in the setting of current infection; it is...

journal_title：Gastroenterology clinics of North America

authors： Brown KE,Peura DA

更新日期：1993-03-01 00:00:00

abstract：:This article reviews the role of therapeutic endoscopy in the diagnosis and treatment of nonvariceal upper and lower gastrointestinal (GI) hemorrhage. The initial approach to patients with GI bleeding is reviewed. Endoscopic treatment of various stigmata of recent peptic ulcer hemorrhage is discussed in detail. Manage...

journal_title：Gastroenterology clinics of North America

authors： Savides TJ,Jensen DM

更新日期：2000-06-01 00:00:00