Morphology and barrier function of the corneal epithelium after penetrating keratoplasty: association with original diseases, tear function, and suture removal.

abstract：PURPOSE:To evaluate the epidemiology of ocular surface squamous neoplasia (OSSN) and its associated risk factors in a South Florida Veterans Affairs Hospital population. METHODS:Retrospective case-control study. Twenty-eight confirmed cases of OSSN from 24,179 veterans who received care at the Miami Veterans Affairs H...

journal_title：Cornea

authors： McClellan AJ,McClellan AL,Pezon CF,Karp CL,Feuer W,Galor A

更新日期：2013-10-01 00:00:00

abstract：PURPOSE:To evaluate the suitability of corneas from septic donors for transplantation by analyzing the discard rate in the eye bank and the clinical outcome of Descemet membrane endothelial keratoplasty (DMEK) using organ-cultured corneal grafts from septic versus nonseptic donors. METHODS:This retrospective study inc...

journal_title：Cornea

authors： Vasiliauskaitė I,de Jong M,Quilendrino R,van der Wees J,Oellerich S,Melles GRJ

更新日期：2021-01-01 00:00:00

abstract：:The present study describes biochemical and morphological differences of pseudophakic bullous keratopathy (PBK) corneas as compared with normal corneas. At the ultrastructural level, all PBK corneas studied had abnormal fibrillar material posterior to the Descemet's membrane. In addition, two of the six PBK buttons ha...

journal_title：Cornea

authors： Kenney MC,Chwa M

更新日期：1990-04-01 00:00:00

abstract：PURPOSE:To quantify all minor/major adverse events in a large cohort of consecutive corneal transplants, particularly in respect to penetrating keratoplasty (PKP). METHODS:All corneal transplants in the Auckland region over a 10-year period (2000-2009) were identified through the New Zealand National Eye Bank. Relevan...

journal_title：Cornea

authors： Crawford AZ,Krishnan T,Ormonde SE,Patel DV,McGhee CN

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:Intrastromal corneal ring segments (ICRSs) are small arc-like implants that are being used increasingly as a minimally invasive treatment for patients with keratoconus. This study assessed the effectiveness of KeraRing implants, a type of ICRS, to treat keratoconus. METHODS:Retrospective case series descriptiv...

journal_title：Cornea

authors： Gharaibeh AM,Muhsen SM,AbuKhader IB,Ababneh OH,Abu-Ameerh MA,Albdour MD

更新日期：2012-02-01 00:00:00

abstract：:A randomized, double-blind, placebo-controlled, multicenter clinical trial was conducted in five centers to assess safety, ocular tolerance, and efficacy of an ophthalmic solution of epidermal growth factor (EGF) for the treatment of traumatic corneal epithelial defects. One hundred four patients completed the study: ...

journal_title：Cornea

authors： Pastor JC,Calonge M

更新日期：1992-07-01 00:00:00

abstract：PURPOSE:The aim of this study was to determine the effect of nicergoline in patients with neurotrophic keratopathy. METHODS:This is a prospective, noncomparative interventional study. The study included 27 eyes of 24 patients with neurotrophic keratopathy who were unresponsive to conventional therapy. Patients were tr...

journal_title：Cornea

authors： Lee YC,Kim SY

更新日期：2015-03-01 00:00:00

abstract：:Fourteen patients presenting with neuropsychiatric manifestations of Wilson's disease were treated with oral tetrathiomolybdate (TM) for 8 weeks followed by oral zinc (Zn) maintenance therapy. The patients were evaluated prospectively at baseline and at yearly intervals for up to 5 years by slit-lamp biomicroscopy and...

journal_title：Cornea

authors： Esmaeli B,Burnstine MA,Martonyi CL,Sugar A,Johnson V,Brewer GJ

更新日期：1996-11-01 00:00:00

abstract：PURPOSE:To investigate the effects of pterygium excision with conjunctival autograft plus corneal polishing on ocular higher-order aberrations (HOAs) and to monitor the changes throughout the first postoperative year. METHODS:A total of 18 eyes of 16 patients with primary pterygium who had an indication for surgical e...

journal_title：Cornea

authors： Gumus K,Topaktas D,Göktaş A,Karakucuk S,Oner A,Mirza GE

更新日期：2012-12-01 00:00:00

abstract：PURPOSE:To describe the incidence and prevalence of glaucoma in a patient population with severe ocular surface disease (OSD). METHODS:A retrospective case series was compiled from all charts of patients in the Cincinnati Eye Institute/University of Cincinnati and University of Minnesota population with a diagnosis of...

journal_title：Cornea

authors： Tsai JH,Derby E,Holland EJ,Khatana AK

更新日期：2006-06-01 00:00:00

abstract：:The pharmacokinetics and toxicity of subconjunctival (S/C) amphotericin B (AmB) were evaluated in Dutch-belted rabbits. Following the S/C injection of 1,500 micrograms of AmB, corneal and aqueous levels were determined by bioassay. The highest levels were present in the periphery of debrided corneas at 1 h (90.12 +/- ...

journal_title：Cornea

authors： O'Day DM,Smith R,Stevens JB,Williams TE,Robinson RD,Head WS

更新日期：1991-09-01 00:00:00

abstract：:The many published studies on sterile procedures used by eye banks have included none until now on ways to optimize sterile handling of corneas procured in the morgues of forensic pathologists. The present study sought to discover if fewer positive cultures would be reported at the time of surgery from corneas which h...

journal_title：Cornea

authors： Farge EJ,Fort RA

更新日期：1985-01-01 00:00:00

abstract：PURPOSE:This review discusses cellular senescence, the state in which normal cells do not respond to growth stimuli, and shows characteristic alterations in their cytologic and biochemical properties and their gene expression profiles. METHODS AND RESULTS:Cellular senescence is elicited by various stresses. It was rec...

journal_title：Cornea

authors： Ishikawa F

更新日期：2006-12-01 00:00:00

abstract：PURPOSE:To report a case of recurrent herpes simplex virus (HSV) epithelial keratitis after intravitreal triamcinolone acetonide injection for the treatment of diabetic macular edema. METHODS:Case report. RESULTS:We describe a case of a 59-year-old woman with a history of ocular HSV disease and severe proliferative d...

journal_title：Cornea

authors： Shtein RM,Stahl RM,Saxe SJ,Mian SI

更新日期：2007-06-01 00:00:00

abstract：PURPOSE:To measure the refractive index (RI) of the human corneal stroma in vivo using an objective Abbé refractometer (VCH-1) and to determine if RI of the stroma is related to age. METHODS:The VCH-1 was calibrated against a standard subjective Abbé refractometer using 7 randomly selected turbid semiliquid media. VCH...

journal_title：Cornea

authors： Patel S,Alió JL,Amparo F,Rodriguez-Prats JL

更新日期：2011-12-01 00:00:00

abstract：PURPOSE:To compare higher-order aberrations (HOAs) after small incision lenticule extraction (SMILE) in patients with and without intraoperative angle kappa adjustments. METHODS:This is a retrospective case series. One hundred six eyes of 106 patients who underwent SMILE at Tianjin Eye Hospital (Tianjin Medical Univer...

journal_title：Cornea

authors： Shao T,Wang Y,Ng ALK,Chan TCY,Hao W,Zhang J,Cheng GPM,Jhanji V

更新日期：2020-05-01 00:00:00

abstract：PURPOSE:To retrospectively evaluate the results of myopic photorefractive keratectomy (PRK) for different levels of intended correction, including analysis of loss of best spectacle-corrected visual acuity. METHODS:Four hundred seventy-five consecutive eyes with 1 year of follow-up that had PRK for the correction of 1...

journal_title：Cornea

authors： Kapadia MS,Wilson SE

更新日期：2000-03-01 00:00:00

abstract：PURPOSE:The study aimed to determine whether detectable concentrations of colchicine are present in the tear fluid of treated patients with familial Mediterranean fever (FMF) and thus demonstrate a possible route by which colchicine reaches the corneal surface. METHODS:Tear fluid samples (50-100 microL) were collected...

journal_title：Cornea

authors： Leibovitch I,Alster Y,Scherrmann JM,Azmon B,Barequet IS,Livneh A,O'Brien TP,Lazar M,Loewenstein A

更新日期：2003-04-01 00:00:00

abstract：PURPOSE:To compare dry eye disease parameters between small incision lenticule extraction (SMILE) and laser subepithelial keratomileusis (LASEK). METHODS:This prospective, nonrandomized study included 39 eyes of 39 patients who underwent SMILE (n = 19) and LASEK (n = 20). Dry eye disease parameters included Ocular Sur...

journal_title：Cornea

authors： Chung B,Choi M,Lee KY,Kim EK,Seo KY,Jun I,Kim KY,Kim TI

更新日期：2020-04-01 00:00:00

abstract：PURPOSE:To investigate the distribution and relative level of expression of the receptor tyrosine kinases, epidermal growth factor receptor (EGFR), ErbB2 and ErbB3, in human ocular surface epithelia. METHODS:Immunofluorescent staining was performed to identify expression of the EGFR, ErbB2 and ErbB3 in the corneal, li...

journal_title：Cornea

authors： Liu Z,Carvajal M,Carraway CA,Carraway K,Pflugfelder SC

更新日期：2001-01-01 00:00:00

abstract：PURPOSE:Microbial keratitis (MK) is a major cause of corneal blindness worldwide. Variations in season and temperature can affect MK incidence due to specific causative organisms; however, few studies have examined these factors in the UK. METHODS:Retrospective review of all corneal scrapes from patients with MK prese...

journal_title：Cornea

authors： Walkden A,Fullwood C,Tan SZ,Au L,Armstrong M,Brahma AK,Chidambaram JD,Carley F

更新日期：2018-12-01 00:00:00

abstract：PURPOSE:To investigate if amniotic membrane incubated with antibiotics could inhibit bacterial growth in vitro. METHODS:Amniotic membrane fragments were incubated with the antibiotics (netilmicin) solution; the washed and drained fragments were either tested after treatment or further incubated in antibiotic-free medi...

journal_title：Cornea

authors： Mencucci R,Menchini U,Dei R

更新日期：2006-05-01 00:00:00

abstract：PURPOSE:To investigate the feasibility of corneal reconstruction utilizing cultured human corneal endothelial cells (HCECs). METHODS:We cultivated HCECs using culture dishes pre-coated with bovine corneal endothelial extracellular matrix. The effect of donor age on HCECs was investigated. We reconstructed corneas usin...

journal_title：Cornea

authors： Amano S

更新日期：2003-10-01 00:00:00

abstract：PURPOSE:To evaluate the potential of human anterior lens capsule (HALC) as a carrier matrix for cultivating and transplanting human corneal endothelial cells (HCECs). METHODS:HALCs obtained from 12 patients during cataract surgery were exposed to enzyme digestion to dissolve the lens epithelium and were plated with th...

journal_title：Cornea

authors： Yoeruek E,Saygili O,Spitzer MS,Tatar O,Bartz-Schmidt KU,Szurman P

更新日期：2009-05-01 00:00:00

abstract：PURPOSE:To evaluate the morphological features of the corneal limbus as measured by in vivo confocal microscopy (IVCM) following standard and accelerated corneal collagen cross-linking (CXL) for keratoconus. METHODS:Patients with progressive keratoconus scheduled to undergo standard CXL (group 1; 31 patients, 3 mW/cm,...

journal_title：Cornea

authors： Uçakhan ÖÖ,Bayraktutar B

更新日期：2017-01-01 00:00:00

abstract：PURPOSE:To investigate the association of systemic diseases with keratoconus in the general Korean population. METHODS:This is a nationwide population-based retrospective cohort study using the Korean National Health Insurance Service-National Sample Cohort database from 2002 to 2015, involving 1,108,369 individuals. ...

journal_title：Cornea

authors： Lee HK,Jung EH,Cho BJ

更新日期：2020-03-01 00:00:00

abstract：PURPOSE:Pterygium excision with conjunctival limbal autograft (CLAG) has been used successfully for prevention of pterygium recurrence. However, long-term follow-up data in the literature are lacking regarding CLAG. METHODS:Retrospective chart review and standard statistical analysis were performed. The records of 289...

journal_title：Cornea

authors： Masters JS,Harris DJ Jr

更新日期：2015-12-01 00:00:00

abstract：PURPOSE:To assess donor rim culture results and outcomes of ocular infections in the Cornea Preservation Time Study (CPTS). METHODS:Donor corneal rim cultures were optional. Donor characteristics were assessed for association with positive cultures using the Fisher exact test and Poisson regression analyses. Incidence...

journal_title：Cornea

authors： Mian SI,Aldave AJ,Tu EY,Ayres BD,Jeng BH,Macsai MS,Nordlund ML,Penta JG,Pramanik S,Szczotka-Flynn LB,Ayala AR,Liang W,Maguire MG,Lass JH

更新日期：2018-09-01 00:00:00

abstract：PURPOSE:To assess the long-term clinical course of dry eye in patients with chronic graft-versus-host disease (cGVHD). METHODS:A prospective case series of 49 patients with cGVHD was conducted. Complete history and ophthalmic examination were performed at baseline and at 36 months (range, 26-53). All patients received...

journal_title：Cornea

authors： Sáles CS,Johnston LJ,Ta CN

更新日期：2011-02-01 00:00:00

abstract：PURPOSE:To describe the management and outcome of an ocular surface alkali burn in the setting of previous laser in situ keratomileusis (LASIK). METHODS:This is a case report and review of relevant literature. RESULTS:A 25-year-old man with a history of LASIK presented 4 weeks after a sodium hydroxide splash to his l...

journal_title：Cornea

authors： Witsberger EM,Patel SV

更新日期：2020-12-03 00:00:00