Pharmacology of eprosartan, an angiotensin II receptor antagonist: exploring hypotheses from clinical data.

abstract：:Electrophysiologic studies were prospectively performed in 91 consecutive patients referred for evaluation of sustained ventricular tachycardia or sudden cardiac death. Fifty-two patients had a history of sustained ventricular tachycardia and 39 patients had a history of sudden cardiac death. The identical stimulation...

journal_title：American heart journal

authors： Oseran DS,Gang ES,Hamer AW,Zaher CA,Rosenthal ME,Mandel WJ,Peter T

更新日期：1985-09-01 00:00:00

abstract：BACKGROUND:Left atrial appendage flow velocity (LAAFV) is a predictor of thromboembolism in atrial fibrillation (AF) patients, as well as CHA2DS2-VASc score. However, little is known about LAAFV in sinus rhythm (SR) after catheter ablation. The aim of this study was to determine clinical predictors of low LAAFV in pati...

journal_title：American heart journal

authors： Kusa S,Komatsu Y,Taniguchi H,Uchiyama T,Takagi T,Nakamura H,Miyazaki S,Hachiya H,Iesaka Y

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Apparent treatment-resistant hypertension (aTRH) is associated with an increased risk of adverse cardiovascular outcomes. We studied the frequency and intensity of care for aTRH among participants aged 65 years and older in the US-based REGARDS study linked with Medicare claims. METHODS:Blood pressure (BP) ...

journal_title：American heart journal

authors： Vemulapalli S,Deng L,Patel MR,Kilgore ML,Jones WS,Curtis LH,Irvin MR,Svetkey LP,Shimbo D,Calhoun DA,Muntner P

更新日期：2017-04-01 00:00:00

abstract：:The results of percutaneous transluminal coronary angioplasty (PTCA) in 307 lesions in 235 patients within 60 days of myocardial infarction (MI) were compared with the PTCA results in 591 lesions in 489 patients without recent MI, and the effect of fibrinolysis to treat recurring occlusive clot during angioplasty was ...

journal_title：American heart journal

authors： Haft JI,Goldstein JE,Homoud MK,Aaronoff M

更新日期：1990-08-01 00:00:00

abstract：BACKGROUND:Older adults presenting with acute myocardial infarction (MI) often have multivessel coronary artery disease amenable to percutaneous coronary intervention (PCI), yet the risks of multivessel intervention may outweigh potential benefits in these patients. We sought to determine if nonculprit intervention dur...

journal_title：American heart journal

authors： Wang TY,McCoy LA,Bhatt DL,Rao SV,Roe MT,Resnic FS,Cavender MA,Messenger JC,Peterson ED

更新日期：2016-02-01 00:00:00

abstract：:There is evidence that the endothelium plays an important role in the control of human vascular tone by releasing endothelium-derived nitric oxide and, therefore, a defective endothelial function could be involved in the increased peripheral vasoconstriction of patients with chronic congestive heart failure. To invest...

journal_title：American heart journal

authors： Drexler H,Hayoz D,Münzel T,Just H,Zelis R,Brunner HR

更新日期：1993-09-01 00:00:00

abstract：:Given the preventable morbidity and mortality associated with atrial fibrillation (AF), increased awareness of undiagnosed AF, and advances in mobile electrocardiogram (ECG) technology, there is a critical need to assess the effectiveness of using such technology to routinely screen for AF in clinical practice. VITAL-...

journal_title：American heart journal

authors： Ashburner JM,Atlas SJ,McManus DD,Chang Y,Trisini Lipsanopoulos AT,Borowsky LH,Guan W,He W,Ellinor PT,Singer DE,Lubitz SA

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Cardiac magnetic resonance (cMR) perfusion imaging is a promising technique to assess coronary artery disease (CAD). Our objective was to evaluate accuracy of various cMR imaging parameters to detect significant CAD as compared with angiography or fractional flow reserve (FFR). METHODS:We prospectively enro...

journal_title：American heart journal

authors： Futamatsu H,Wilke N,Klassen C,Shoemaker S,Angiolillo DJ,Siuciak A,Morikawa-Futamatsu K,Suzuki N,von Ziegler F,Bass TA,Costa MA

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:Embolic events to the central nervous system are a major cause of morbidity and mortality in patients with infective endocarditis (IE). The appropriate role of valvular surgery in reducing such embolic events is unclear. The purpose of this study was to determine the relationship between the initiation of an...

journal_title：American heart journal

authors： Dickerman SA,Abrutyn E,Barsic B,Bouza E,Cecchi E,Moreno A,Doco-Lecompte T,Eisen DP,Fortes CQ,Fowler VG Jr,Lerakis S,Miro JM,Pappas P,Peterson GE,Rubinstein E,Sexton DJ,Suter F,Tornos P,Verhagen DW,Cabell CH,ICE In

更新日期：2007-12-01 00:00:00

abstract：:Two double-blind multicenter studies compared acebutolol with placebo (acebutolol, N = 121; placebo, N = 116) and with propranolol (acebutolol, N = 186; propranolol, N = 190) in essential hypertension. Acebutolol significantly reduced mean sitting diastolic blood pressure from 99.2 +/- 0.3 mm Hg at baseline to 89.1 +/...

journal_title：American heart journal

authors： Davidov M

更新日期：1985-05-01 00:00:00

abstract：:The effects and possible mechanisms of actions of indomethacin on systemic and coronary hemodynamics were studied in 17 patients with coronary artery disease. Group I patients (12) were given either indomethacin or placebo in the absence of prior cyclooxygenase inhibition and group II (five) were given indomethacin af...

journal_title：American heart journal

authors： Forman MB,Uderman H,Jackson EK,Roy L,Bostick D,Robertson D,Robertson RM

更新日期：1985-08-01 00:00:00

abstract：BACKGROUND:Surgical ventricular restoration (SVR) is an operation that demonstrates promise to improve outcomes for patients with left ventricular dysfunction. Current use and operative outcomes of SVR have come from centers of expertise, and operative risks of SVR in community practice are unknown. We sought to charac...

journal_title：American heart journal

authors： Hernandez AF,Velazquez EJ,Dullum MK,O'Brien SM,Ferguson TB,Peterson ED

更新日期：2006-09-01 00:00:00

abstract：:The recognition that the onset of cardiovascular events follows a circadian periodicity and is frequently triggered by physical or mental stresses has created new possibilities for disease prevention. Morning peaks in occurrence are now well-documented for acute myocardial infarction, sudden cardiac death, transient m...

journal_title：American heart journal

authors： Muller JE

更新日期：1999-04-01 00:00:00

abstract：:To evaluate the potential for hyperbaric oxygen (HBO) to produce transient improvement in function in areas of myocardium ischemic at rest (hibernating myocardium), 24 patients were studied within 1 week of acute myocardial infarction. Results were compared with single-photon emission computed tomography (SPECT) thall...

journal_title：American heart journal

authors： Swift PC,Turner JH,Oxer HF,O'Shea JP,Lane GK,Woollard KV

更新日期：1992-11-01 00:00:00

abstract：:Four hundred and ninety-two patients with coronary artery disease underwent analysis of their electrocardiograms, coronary arteriograms, and ventriculograms. Significant Q-waves were correlated with critical coronary occlusions (greater than or equal 75 per cent obstruction) and ventricular contractility. It was found...

journal_title：American heart journal

authors： Gottlieb RS,Duca PR,Kasparian H,Scariato A,Brest AN

更新日期：1975-10-01 00:00:00

abstract：BACKGROUND:ISAR-REACT was a trial designed to evaluate whether the glycoprotein IIb/IIIa inhibitor abciximab is beneficial in patients undergoing elective percutaneous coronary intervention (PCI) with stent placement after pretreatment with a 600 mg loading dose of clopidogrel. Objective for the angiographic substudy w...

journal_title：American heart journal

authors： Schühlen H,Kastrati A,Mehilli J,Hausleiter J,Dirschinger J,Dotzer F,Bollwein H,Schömig A

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:Diastolic dysfunction induced by ischemia may alter transmitral blood flow, but this reflects global ventricular function, and pseudonormalization may occur with increased preload. Tissue Doppler may assess regional diastolic function and is relatively load-independent, but limited data exist regarding its a...

journal_title：American heart journal

authors： Najos-Valencia O,Cain P,Case C,Wahi S,Marwick TH

更新日期：2002-09-01 00:00:00

abstract：:The QRS complex and ST segment in the ECGs of 80 patients who died of an acute myocardial infarction (MI) were studied in relation to the extent of the MI (subendocardial vs. transmural). Changes in the QRS complex developed in nine out of the 15 cases with an acute subendocardial MI. Five of these cases fulfilled the...

journal_title：American heart journal

authors： Raunio H,Rissanen V,Romppanen T,Jokinen Y,Rehnberg S,Helin M,Pyörälä K

更新日期：1979-08-01 00:00:00

abstract：BACKGROUND:Anginal chest pain without creatine kinase (CK) elevation is frequently observed in the first hours after coronary stenting. Possible causes of ischemic episodes are microembolism, side branch occlusion, coronary vasospasm, and disturbances of microvascular circulation. In a prospective, double-blind, random...

journal_title：American heart journal

authors： Kurz DJ,Naegeli B,Bertel O

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Many US studies have documented an association between operator volume and outcomes after percutaneous coronary intervention (PCI). No study has assessed whether this relationship exists in Canada, where PCI is performed only at a limited number of regional centers and operator volumes are higher. METHODS:A...

journal_title：American heart journal

authors： Cantor WJ,Hall R,Tu JV

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:Dual antiplatelet therapy with aspirin and clopidogrel is currently recommended in off-pump coronary artery bypass (OPCAB). However, no data exist concerning platelet reactivity on clopidogrel after OPCAB. The aim of this study was to assess the relationship between platelet reactivity and late major adverse...

journal_title：American heart journal

authors： Youn YN,Yi G,Lee S,Joo HC,Yoo KJ

更新日期：2014-06-01 00:00:00

abstract：:Plasma concentrations of immunoreactive alpha-human atrial natriuretic polypeptide (i alpha-hANP) and cyclic guanosine monophosphate (cGMP) were measured in 70 patients with heart disease. Plasma concentrations of i alpha-hANP were directly related to the severity of heart disease (F = 29.61, p less than 0.001). Plasm...

journal_title：American heart journal

authors： Hirata Y,Ishii M,Matsuoka H,Sugimoto T,Iizuka M,Uchida Y,Serizawa T,Sato H,Kohmoto O,Mochizuki T

更新日期：1987-06-01 00:00:00

abstract：:We tested the efficacy of microwave-frequency energy for ablating atrial tachycardia in eight open-chest dogs. Five other dogs served as controls. Atrial tachycardia was induced by direct application of aconitine crystals to the epicardial atrial surface or by injection of aconitine solution (0.15 mg/ml) into the righ...

journal_title：American heart journal

authors： Rho TH,Ito M,Pride HP,Waller B,Zipes DP

更新日期：1995-05-01 00:00:00

abstract：:Quinidine binding was studied in 15 survivors of prehospital cardiac arrest and was compared to 18 normal individuals and 20 patients with coronary artery disease. The unbound quinidine fraction was 6.3 +/- 2.8% in the survivors of prehospital cardiac arrest, a value significantly lower than normal individuals (unboun...

journal_title：American heart journal

authors： Kessler KM,Lisker B,Conde C,Silver J,Ho-Tung P,Hamburg C,Myerburg RJ

更新日期：1984-04-01 00:00:00

abstract：:We evaluated the use of simple balloon overinflation to induce neointimal hyperplasia in a porcine model of coronary artery restenosis. By using standard percutaneous transluminal coronary angioplasty techniques, left anterior descending (LAD) and/or left circumflex (LCX) coronary arteries of either juvenile feeder pi...

journal_title：American heart journal

authors： Humphrey WR,Simmons CA,Toombs CF,Shebuski RJ

更新日期：1994-01-01 00:00:00

abstract：:Abnormal interventricular septal motion is a frequent finding after cardiac surgery. However, the time course and underlying mechanisms are not well understood. Nineteen patients, mean age 54 years (range 20 to 82 years), were studied with intraoperative transesophageal echocardiography at five specific times: with th...

journal_title：American heart journal

authors： Wranne B,Pinto FJ,Siegel LC,Miller DC,Schnittger I

更新日期：1993-07-01 00:00:00

abstract：BACKGROUND:Patients with chronic kidney disease (CKD) experience poor outcomes after acute myocardial infarction (AMI). We sought to compare clinical characteristics of advanced CKD, dialysis, and non-CKD patients hospitalized with AMI. METHODS:This observational study used record-linked data from the US Renal Data Sy...

journal_title：American heart journal

authors： Shroff GR,Frederick PD,Herzog CA

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:In patients with severe pulmonary hypertension (PH), right ventricular function is a main determinant of clinical stability and outcome. Supraventricular tachyarrhythmias (SVTs) may compromise cardiac function and threaten prognosis in patients with PH, but the incidence and clinical relevance of SVTs in PH ...

journal_title：American heart journal

authors： Tongers J,Schwerdtfeger B,Klein G,Kempf T,Schaefer A,Knapp JM,Niehaus M,Korte T,Hoeper MM

更新日期：2007-01-01 00:00:00

abstract：:We developed a new angiographic score of the extent of coronary disease (extent score), which we compared with conventional stenosis and vessel scores that emphasize the severity of stenosis. Scores were determined in 132 patients (29 women, 103 men with a mean age of 55 +/- 10 years) who underwent elective coronary a...

journal_title：American heart journal

authors： Sullivan DR,Marwick TH,Freedman SB

更新日期：1990-06-01 00:00:00

abstract：:Release of thromboxane (TXA2) during acute myocardial infarction may be an important contributing factor in the genesis of ventricular fibrillation (VF). We assessed the effect of selective TXA2 inhibition on vulnerability to VF after total occlusion of the anterior descending coronary artery in chloralose-anesthetize...

journal_title：American heart journal

authors： O'Connor KM,Friehling TD,Kelliher GJ,MacNab MW,Wetstein L,Kowey PR

更新日期：1986-04-01 00:00:00