Psychotropic medication withdrawal and a home-based exercise program to prevent falls: a randomized, controlled trial.

Abstract:

OBJECTIVE:To assess the effectiveness of psychotropic medication withdrawal and a home-based exercise program in reducing falls in older people. DESIGN:A randomized controlled trial with a two by two factorial design. SETTING:Seventeen general practices in Dunedin, New Zealand. PARTICIPANTS:Women and men aged 65 years registered with a general practitioner and currently taking psychotropic medication (n = 93). INTERVENTIONS:Two interventions: (1) gradual withdrawal of psychotropic medication versus continuing to take psychotropic medication (double blind) and (2) a home-based exercise program versus no exercise program (single blind). MEASUREMENTS:Number of falls and falls risk during 44 weeks of follow-up. Analysis was on an intent to treat basis. RESULTS:After 44 weeks, the relative hazard for falls in the medication withdrawal group compared with the group taking their original medication was .34 (95% CI, .16-.74). The risk of falling for the exercise program group compared with those not receiving the exercise program was not significantly reduced. CONCLUSIONS:Withdrawal of psychotropic medication significantly reduced the risk of falling, but permanent withdrawal is very difficult to achieve.

journal_name

J Am Geriatr Soc

authors

Campbell AJ,Robertson MC,Gardner MM,Norton RN,Buchner DM

doi

10.1111/j.1532-5415.1999.tb03843.x

subject

Has Abstract

pub_date

1999-07-01 00:00:00

pages

850-3

issue

7

eissn

0002-8614

issn

1532-5415

journal_volume

47

pub_type

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