A novel biochemical approach to congestive heart failure: cardiac troponin T.

abstract：:We performed a chronologic investigation of left (LV) and right (RV) ventricular myosin ATPase activity and hemodynamics in newborn lambs. We found an elevation in myosin ATPase activity for the LV, which was achieved by 6 to 8 weeks of age and which correlated directly with increasing ventricular stroke work. Myosin ...

journal_title：American heart journal

authors： Riemenschneider TA,Brenner RA,Wikman-Coffelt J,Mason DT

更新日期：1982-05-01 00:00:00

abstract：:Although the Doppler mitral flow velocity pattern changes in accordance with the degree of left ventricular diastolic dysfunction, it is "normalized" in the presence of heart failure. In this study the pulmonary venous flow velocity pattern was characterized in 43 hypertensive patients with and without heart failure t...

journal_title：American heart journal

authors： Masuyama T,Lee JM,Yamamoto K,Tanouchi J,Hori M,Kamada T

更新日期：1992-10-01 00:00:00

abstract：:The acute electrophysiologic effects of a bolus injection of 100 mg. of lidocaine were investigated in 39 patients with impulse formation and conduction defects by means of His-bundle recording and were correlated with plasma lidocaine levels. The effects of therapeutic plasma levels on conduction intervals and refrac...

journal_title：American heart journal

authors： Roos JC,Dunning AJ

更新日期：1975-06-01 00:00:00

abstract：:Hypertensive cardiovascular risk may be related primarily to vascular overload, the sum of three vascular abnormalities: increased arteriolar resistance, increased large-artery stiffness, and the effect of increased early pulse-wave reflection. A method for quantifying vascular overload as an index can be derived from...

journal_title：American heart journal

authors： Franklin SS,Weber MA

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:Aortopulmonary collaterals (APCs) are frequently observed before and after the Fontan procedure. However, the mechanism of the development of APCs is unknown. We hypothesized that one or several antiangiogenic and/or angiogenic growth factors might play a role in the development of APCs. METHODS:Eighty-five...

journal_title：American heart journal

authors： Mori Y,Shoji M,Nakanishi T,Fujii T,Nakazawa M

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:The IMProved Reduction of Outcomes: Vytorin Efficacy International Trial (IMPROVE-IT) is evaluating the potential benefit for reduction in major cardiovascular (CV) events from the addition of ezetimibe versus placebo to 40 mg/d of simvastatin therapy in patients who present with acute coronary syndromes and...

journal_title：American heart journal

authors： Blazing MA,Giugliano RP,Cannon CP,Musliner TA,Tershakovec AM,White JA,Reist C,McCagg A,Braunwald E,Califf RM

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:There are limited data regarding the clinical correlates and prognostic significance of echocardiographically defined mitral regurgitation (MR) early after acute myocardial infarction (MI). The current study addressed these issues. METHODS:Seven hundred thirty-seven patients with acute MI who underwent tran...

journal_title：American heart journal

authors： Hillis GS,Møller JE,Pellikka PA,Bell MR,Casaclang-Verzosa GC,Oh JK

更新日期：2005-12-01 00:00:00

abstract：:In 30 years of follow-up in the Framingham study, routine biennial ECG examinations revealed 315 subjects with ECG-LVH and 164 with unrecognized ECG-MI without previous cardiac explanation. Among subjects initially free of clinically evident coronary heart disease and both ECG abnormalities, the incidence of ECG-LVH w...

journal_title：American heart journal

authors： Kannel WB,Abbott RD

更新日期：1986-02-01 00:00:00

abstract：OBJECTIVES:To define the incidence and cumulative risk of atrial fibrillation (AF) in a population-based cohort of whites and African Americans. BACKGROUND:African-Americans reportedly have a lower risk of AF than whites despite their higher exposure to AF risk factors. However, precise estimates of AF incidence in Af...

journal_title：American heart journal

authors： Alonso A,Agarwal SK,Soliman EZ,Ambrose M,Chamberlain AM,Prineas RJ,Folsom AR

更新日期：2009-07-01 00:00:00

abstract：:Motion of the posterior aortic root on echocardiography is related to left atrial volume changes. Early diastolic posterior motion of the aortic root reflects both LA emptying and filling and has been measured as the atrial emptying index. To study late diastolic motion of the aortic root, we measured the slope of pos...

journal_title：American heart journal

authors： Ambrose JA,Martinez EE,Meller J,Gorlin R,Pichard AD,Herman MV,Teichlolz LE

更新日期：1980-10-01 00:00:00

abstract：BACKGROUND:Elevated resting heart rate (RHR) is known to be associated with reduced survival but inconsistencies remain, including lack of significance in most studies of healthy women, lack of independence from systolic blood pressure (SBP) in some, and the suggestion that RHR is merely functioning as a marker of phys...

journal_title：American heart journal

authors： Cooney MT,Vartiainen E,Laatikainen T,Juolevi A,Dudina A,Graham IM

更新日期：2010-04-01 00:00:00

abstract：:MAT is an uncommon arrhythmia most often seen in elderly patients with chronic pulmonary disease who are critically ill due to acute respiratory or cardiac decompensation. Its importance lies in the fact that it is commonly mistaken for AF, since both disorders are characterized by narrow ventricular complexes, irregu...

journal_title：American heart journal

authors： Scher DL,Arsura EL

更新日期：1989-09-01 00:00:00

abstract：:The purpose of this study was to determine the normal pattern and magnitude of mitral annular velocities in diastole by Doppler tissue imaging (DTI) and to assess whether this is altered in patients with left ventricular hypertrophy. Mitral annulus velocities were measured by DTI. Peak and time-velocity integral were ...

journal_title：American heart journal

authors： Rodriguez L,Garcia M,Ares M,Griffin BP,Nakatani S,Thomas JD

更新日期：1996-05-01 00:00:00

abstract：:Recently developed unstable angina clinical practice guidelines have recommended risk stratification with dipyridamole thallium-201 myocardial imaging in patients at "intermediate" pretest clinical risk who cannot exercise maximally. The prognostic value of predischarge dipyridamole technetium 99m sestamibi (MIBI) tom...

journal_title：American heart journal

authors： Stratmann HG,Tamesis BR,Younis LT,Wittry MD,Amato M,Miller DD

更新日期：1995-10-01 00:00:00

abstract：:Adequate hydration is recommended for acute ST-elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PCI) to prevent contrast-induced nephropathy (CIN). However, the optimal hydration regimen has not been well established in these high-risk patients. The objective of t...

journal_title：American heart journal

authors： Liu Y,Chen JY,Huo Y,Ge JB,Xian Y,Duan CY,Chen SQ,Jiang W,Chen PY,Tan N,RESCIND group.

更新日期：2016-02-01 00:00:00

abstract：:Reperfusion therapy has lowered the mortality in patients suffering acute myocardial infarction. Failure to reperfuse is associated with significantly higher risk of short- and long-term mortality. Detection of reperfusion is thus important. In a prospective pilot study, we used continuous on-line computerized vectorc...

journal_title：American heart journal

authors： Dellborg M,Topol EJ,Swedberg K

更新日期：1991-10-01 00:00:00

abstract：BACKGROUND:The aim of this study was to describe the effect of intravenous metoprolol on the intensity of chest pain before hospital admission in patients with suspected acute myocardial infarction AMI). METHODS AND RESULTS:Two hundred sixty-two patients with acute chest pain and suspected AMI were randomly assigned b...

journal_title：American heart journal

authors： Gardtman M,Dellborg M,Brunnhage C,Lindkvist J,Waagstein L,Herlitz J

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:We review our 10-year experience of mitral valve (MV) repair in comparison with MV replacement in the elderly for floppy mitral valves/mitral valve prolapse (FMV/MVP). The use of MV repair for this entity has not been fully utilized by surgeons. METHODS:Two hundred ninety-two consecutive patients aged > or ...

journal_title：American heart journal

authors： Gogbashian A,Sepic J,Soltesz EG,Nascimben L,Cohn LH

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:Despite clopidogrel therapy, patients undergoing percutaneous coronary intervention (PCI) with stenting are at risk of recurrent coronary events. This could be partly explained by a reduced efficacy of clopidogrel to inhibit platelet aggregation, an ex vivo defined phenomenon called clopidogrel nonresponsive...

journal_title：American heart journal

authors： Snoep JD,Hovens MM,Eikenboom JC,van der Bom JG,Jukema JW,Huisman MV

更新日期：2007-08-01 00:00:00

abstract：:Acute myocardial infarction (MI) patients remain at high risk for recurrent events. Cholesterol efflux, mediated by apolipoprotein A-I, removes excess cholesterol from atherosclerotic plaque and transports it to the liver for excretion. Impaired cholesterol efflux is associated with higher cardiovascular (CV) event ra...

journal_title：American heart journal

authors： Gibson CM,Kastelein JJP,Phillips AT,Aylward PE,Yee MK,Tendera M,Nicholls SJ,Pocock S,Goodman SG,Alexander JH,Lincoff AM,Bode C,Duffy D,Heise M,Berman G,Mears SJ,Tricoci P,Deckelbaum LI,Steg PG,Ridker P,Mehran R

更新日期：2021-01-01 00:00:00

abstract：:Patients with intractable heart failure (New York Heart Association [NYHA] class III and IV) who were receiving maximal conventional treatment were enrolled in an outpatient program that included inotropic infusions, intensive patient education, and close follow-up. The effects of this approach to therapy were evaluat...

journal_title：American heart journal

authors： Marius-Nunez AL,Heaney L,Fernandez RN,Clark WA,Ranganini A,Silber E,Denes P

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND:The conventional use of 16-slice multidetector computed tomography (MDCT) remains somewhat limited for evaluating stenoses in vein graft distal anastomotic sites and in coronary arteries. We investigated the diagnostic accuracy of 64-slice MDCT for assessment of both grafts and coronary arteries in patients ...

journal_title：American heart journal

authors： Onuma Y,Tanabe K,Chihara R,Yamamoto H,Miura Y,Kigawa I,Fukuda S,Miyairi T,Nakajima H,Hara K

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:Declines in case fatality post-myocardial infarction (MI) have been observed over the past 3 decades. Few studies report socioeconomic disparities in survival post-MI. METHODS:We assessed 1-year case fatality among 9,116 incident MI patients included in the Atherosclerosis Risk in Communities community surv...

journal_title：American heart journal

authors： Foraker RE,Patel MD,Whitsel EA,Suchindran CM,Heiss G,Rose KM

更新日期：2013-01-01 00:00:00

abstract：:The prognostic significance of changes in the mode of induction of ventricular tachycardia (VT) noted during therapy was studied in 49 patients with sustained VT or ventricular fibrillation. Before treatment, all patients had inducible sustained VT by programmed stimulation (one to three extrastimuli) and frequent (gr...

journal_title：American heart journal

authors： Kim SG,Felder SD,Seiden SW,Waspe LE,Fisher JD

更新日期：1987-11-01 00:00:00

abstract：BACKGROUND:Subcortical small vessel disease, represented as white matter hyperintensity (WMH) on magnetic resonance images (MRI) is associated with functional decline in older people with hypertension. We evaluated the relationships of clinic and out-of-office blood pressures (BP) with WMH and functional status in olde...

journal_title：American heart journal

authors： White WB,Jalil F,Wakefield DB,Kaplan RF,Bohannon RW,Hall CB,Moscufo N,Fellows D,Guttmann CRG,Wolfson L

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVE:The study aimed to determine the impact on eptifibatide-associated bleeding by implementing a computerized dosing algorithm in the cardiac catheterization suite. BACKGROUND:Excessive dosing of eptifibatide is associated with increased bleeding rates and hospital mortality. Although dosing adjustments based o...

journal_title：American heart journal

authors： Putney DR,Kleiman NS,Fromm RE Jr,Buergler JM

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Although high-sensitivity cardiac troponin (hs-cTn) substantially improves the early detection of myocardial injury, it lacks specificity for acute myocardial infarction (MI). In suspected non-ST-elevation MI, invasive coronary angiography (ICA) remains necessary to distinguish between acute MI and noncorona...

journal_title：American heart journal

authors： Smulders MW,Kietselaer BL,Das M,Wildberger JE,Crijns HJ,Veenstra LF,Brunner-La Rocca HP,van Dieijen-Visser MP,Mingels AM,Dagnelie PC,Post MJ,Gorgels AP,van Asselt AD,Vogel G,Schalla S,Kim RJ,Bekkers SC

更新日期：2013-12-01 00:00:00

abstract：:Meta-analyses of major outcome trials have demonstrated that the benefits of antihypertensive treatment for reduction of the incidence of stroke are entirely consistent with the benefits predicted from epidemiologic data; however, there remains a shortfall in the expected reduction of the incidence of coronary heart d...

journal_title：American heart journal

authors： Meredith PA

更新日期：1996-07-01 00:00:00

abstract：:Occlusion of the right coronary artery (RCA) in the dog is associated with spontaneous sustained ventricular tachycardia (VT) during the 18 to 26 hours post occlusion period. Electrophysiologic studies suggest that these tachycardias are caused mainly by an automatic mechanism. In the present study we evaluated in 16 ...

journal_title：American heart journal

authors： Karagueuzian HS,Sugi K,Ohta M,Mandel WJ,Peter T

更新日期：1986-03-01 00:00:00

abstract：BACKGROUND:The diagnosis of angina is challenging because it relies on symptom descriptions. Natural language processing (NLP) of the electronic medical record (EMR) can provide access to such information contained in free text that may not be fully captured by conventional diagnostic coding. OBJECTIVE:To test the hyp...

journal_title：American heart journal

authors： Pakhomov SS,Hemingway H,Weston SA,Jacobsen SJ,Rodeheffer R,Roger VL

更新日期：2007-04-01 00:00:00