Abstract:
:We took biopsies from similar sites on the scalps of normal controls, normal looking and hair loss areas of patients with alopecia areata. The specimens were sectioned serially and horizontally. We measured morphological parameters, such as the diameter of the hair shaft, the thickness of the inner root sheath, the diameter of the outer root sheath, the irregularity of the outer root sheath and the ratio between the diameters of the hair shaft and the outer root sheath, using a computerized image analysis system. There were significant differences in 5 parameters between hair loss areas and normal controls. The proportions of vellus and telogen hair were significantly higher in the areata areas than in the controls. The 5 morphological parameters and most quantitative-measured parameters of normal-looking areas from patients with alopecia values intermediate between the other groups.
journal_name
Acta Derm Venereoljournal_title
Acta dermato-venereologicaauthors
Kim IH,Jo HY,Cho CG,Choi HC,Oh CHdoi
10.1080/000155599750011002subject
Has Abstractpub_date
1999-05-01 00:00:00pages
214-6issue
3eissn
0001-5555issn
1651-2057journal_volume
79pub_type
杂志文章abstract::We used T-cell receptor excision circles (TREC) to evaluate thymic function in adult patients with atopic dermatitis and psoriasis. We observed that men, but not women, with atopic dermatitis had a significantly faster decline in TREC content with increasing age compared with healthy men. In contrast, both men and wom...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.2340/00015555-0550
更新日期:2008-01-01 00:00:00
abstract::Nineteen immunocompromised patients with extensive skin lesions caused by Pseudomonas aeruginosa with or without P. aeruginosa bacteremia were analysed. Patients whose lesions originated in the skin were in the majority (14 patients). Skin lesions were located at the site of entry of bacteria (apocrine areas in 12 pat...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract::Eosinophilic pustular folliculitis is an inflammatory skin disease characterized by pruritic follicular papulopustules. It is usually resistant to topical and/or systemic corticosteroids, but it responds well to systemic indomethacin. We report here two patients with classical-type disease who were treated with system...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.2340/00015555-0759
更新日期:2010-01-01 00:00:00
abstract::Intraepidermal collections of neutrophils and lymphocytes are unique features of the inflammatory reaction of psoriasis. Migration of leukocytes from dermis to the epidermis suggests a role for chemotactic agent(s). In recent years, increased levels of chemokines such as IL-8 , GRO-a and MCP-1 have been reported in th...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.1080/000155599750011615
更新日期:1999-01-01 00:00:00
abstract::Skin microdialysis is an established method for in vivo sample collection from the extracellular fluid space. This method has been extensively used in studies of inflammatory reactions in the skin of animals and humans. Skin microdialysis consists of the implantation of semi-permeable probes into the upper dermis, per...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章,评审
doi:10.2340/00015555-1878
更新日期:2014-09-01 00:00:00
abstract::Patients with mood depression have been found to have a higher prevalence of seborrheic dermatitis (SD), possibly related to their tendency to live indoors. The prevalence of outpatients with SD has now been found to be directly related to the number of gloomy days in the area. Since UV light might not be the only rea...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract::The delayed-type immune reactivities of 39 patients suffering from moderate to severe papulopustular or nodulo-cystic forms of Acne vulgaris were compared with healthy acne-free controls. In vivo reactivity was assessed by skin testing with four common recall antigens. In vitro the afferent arm of the immune system wa...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:
更新日期:1980-01-01 00:00:00
abstract::Skin biopsies from a collodion baby, spontaneously healing at the end of the third month, were taken on the 1st and 15th day after delivery and examined by light and electron microscopy. The microscopical features observed were different from those known to occur in collodion babies evolving into lamellar ichthyosis a...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:
更新日期:1981-01-01 00:00:00
abstract::The proportions of suppressor T cells (TG) and helper T cells (TM) were determined in 5 patients with Mycosis fungoides (MF), 4 patients with parapsoriasis en plaques/poikiloderma atrophicans vasculare and 3 patients with generalized chronic dermatitis. All the MF patients showed increased proportions of suppressor T ...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:
更新日期:1980-01-01 00:00:00
abstract::The effect on dermographic wealing of an H1 and H2 receptor antagonist was studied separately and in combination. a double-blind protocol was used and dermographism was measured as the diameter of weal response to a measured force. Both H1 and H2 antagonists had a small but non-significant effect, but the combination ...
journal_title:Acta dermato-venereologica
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1983-01-01 00:00:00
abstract::Twenty-six patients with chronic dermatophytosis (CD) by Trichophyton rubrum (TR) through one year were included in a double-blind clinical trial with Levamisole/Placebo. All patients were treated with griseofulvin concomitantly. Before, during and after the trial, studies of the cellular and humoral immune response w...
journal_title:Acta dermato-venereologica
pub_type: 临床试验,杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract::This is the first case in the literature describing naevi spili, café-au-lait spots and melanocytic naevi aggregated along-side Blaschko's lines. The pattern of melanocytic lesions in our patient is different from the congenital pigmentary syndromes and the segmental distribution of melanocytic naevi, the quadrant dis...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章,评审
doi:10.1080/000155598443114
更新日期:1998-09-01 00:00:00
abstract::Mast cells are thought to be involved in neurogenic inflammation in skin, and numerous neuropeptides are known to degranulate mast cells. We monitored histamine release in skin in situ with the microdialysis method after skin challenge with neuropeptide injections (10 microM substance P, vasoactive intestinal peptide ...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.2340/0001555576205209
更新日期:1996-05-01 00:00:00
abstract::Both spontaneous and inducible forms of chronic urticaria pose a significant economic burden and have an adverse effect on patients' quality of life. The international guidelines and US practice parameters for the diagnosis and management of chronic urticaria both recommend performing a thorough patient history and ph...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章,评审
doi:10.2340/00015555-2496
更新日期:2017-02-08 00:00:00
abstract::Cutaneous adverse effects of imatinib mesylate (Glivec) are common and various types of skin eruptions have been reported. We report here a 57-year-old man who presented with lichen planus-like lesions on his extremities and palmoplantar hyperkeratosis due to the use of imatinib mesylate for chronic myeloid leukaemia....
journal_title:Acta dermato-venereologica
pub_type: 杂志文章,评审
doi:10.2340/00015555-0758
更新日期:2010-01-01 00:00:00
abstract::Generalized normolipemic plane xanthomatosis is a rare cutaneous disorder, frequently associated with reticuloendothelial diseases and some disorders with inflammation. Relapsing polychondritis is also a rare disease that shows an association with various immune-mediated diseases. We report a case of generalized normo...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.2340/0001555574221223
更新日期:1994-05-01 00:00:00
abstract::Eosinophilic pustular folliculitis is a rare dermatosis. Recently, in addition to oral indomethacin, other treatments have been applied for eosinophilic pustular folliculitis. The aim of this study was to assess the effectiveness of various therapies encompassing conventional to newly applied drugs for eosinophilic pu...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.2340/00015555-0578
更新日期:2009-01-01 00:00:00
abstract::Atopic dermatitis (AD) has a big impact on quality of life. The usefulness of health-related quality of life questionnaires for children with AD in general practice, and the relationship of quality of life to disease severity, as assessed by parents and by investigators, however, is not known. This study used the Infa...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.2340/00015555-1026
更新日期:2011-03-01 00:00:00
abstract::Retinoid transfer into breast milk was studied in a psoriatric woman receiving oral acitretin at a dosage of 40 mg once daily. Concentrations of the parent compound and its main metabolite, 13-cis acitretin, were measured in serum and mature milk during the initial nine days of therapy, using reverse-phase high perfor...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:102340/0001555570487490
更新日期:1990-01-01 00:00:00
abstract::Pigmented basal cell carcinomas can be difficult to distinguish clinically from melanoma. Dermoscopy has proven to be useful in the differential diagnosis of the two tumour types. SIAscopy (Spectrophotometric intracutaneous analysis) is a fairly new technique of imaging pigmented skin lesions that has been presented p...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.2340/00015555-0234
更新日期:2007-01-01 00:00:00
abstract::The immunological activity in the cerebrospinal fluid (CSF) was studied in 47 patients with early syphilis. The immunoglobulin production within the central nervous system (CNS) was estimated by analysing immunoglobulin G and albumin in CSF and serum and constructing an IgG index according to Tibbling et al. and calcu...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:
更新日期:1983-01-01 00:00:00
abstract::We set out to show that the assumption is incorrect that continuous treatment with cyclosporin is necessary in psoriasis, as this tenet forms a basis for current recommended treatment regimens. Sixty patients with mild to moderate plaque psoriasis were allocated at random to treatment with oral cyclosporin 5 mg/kg/day...
journal_title:Acta dermato-venereologica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.2340/00015555756569
更新日期:1995-01-01 00:00:00
abstract::The ultrastructure of oral lesions in 6 patients with erythema multiforme (EM) and of one apparently clinically healthy oral mucosa in one patient with recurrent EM during remission is described. Alterations were observed in epithelium, basal lamina and lamina propria. Both intercellular and intracellular oedema, intr...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:102340/0001555570199203
更新日期:1990-01-01 00:00:00
abstract::Cutaneous larva migrans is a dermatitis, typically acquired in warm tropical or sub-tropical countries, caused by migration of the larvae of nematodes (hookworm; mainly Ancylostoma braziliense and, occasionally, Ancylostoma caninum or Uncinaria stenocephala), which are parasitic on animals such as cats and dogs, into ...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章,评审
doi:10.2340/00015555-3217
更新日期:2019-07-01 00:00:00
abstract::The effect of five corticosteroid ointments on epidermal thickness was studied using occlusive chamber application. Thinning of the epidermis and telangiectasia were noted 3 weeks after application of betamethasone-17-valerate (BV), budesonide (BD), clobetasol-17-propionate (CP), and fluocinolone acetonide (FA), but n...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract::Despite advances in atopic dermatitis (AD) treatments, research into AD prevention has been slow. Systematic reviews of prevention strategies promoting exclusive and prolonged breastfeeding, or interventions that reduce ingested or airborne allergens during pregnancy and after birth have generally not shown convincing...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.2340/00015555-3516
更新日期:2020-06-09 00:00:00
abstract::Infection of skin with Candida albicans is usually followed by infiltration of neutrophil granulocytes (PMN). So far, chemotaxins for PMN have been isolated from C. albicans cultures grown in the presence of glucose. However, since glucose is not present in skin in vivo, a contribution of such factors to Candida-trigg...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:102340/000155557213
更新日期:1992-01-01 00:00:00
abstract::Four patients with classic recalcitrant prurigo nodularis had symptomatic and physical responses to thalidomide with remissions. Three of the four patients had increased IgE levels that decreased during therapy. In two patients, short-term treatment (2 to 3 months) was not sufficient to produce remission, but retreatm...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract::The role of cell-mediated immunity in controlling Basal Cell Carcinoma (BCC) growth was studied by measuring the transformation of lymphocytes when challenged in vitro with aqueous extracts of the patients' BCCs and of control skin. Tests were carried out in the presence of autologous and heat-treated plasma. Three pa...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:
更新日期:1981-01-01 00:00:00
abstract::Eye colour, hair colour and skin colour are important risk factors for malignant melanoma and non-melanoma skin cancers. There are few studies in which the distribution of these pigmentary factors in risk populations has been assessed. The purpose of this study was to investigate the prevalence of the major eye and ha...
journal_title:Acta dermato-venereologica
pub_type: 杂志文章
doi:10.1080/000155598441567
更新日期:1998-05-01 00:00:00