Benefits and safety of hepatic resection for colorectal metastases.

Abstract:

BACKGROUND:Metastatic colorectal carcinoma to the liver is a potentially curable disease. The purpose of this study was to determine the safety and efficacy of hepatic resection for metastatic colorectal carcinoma. METHODS:One hundred twenty-one consecutive hepatic resections in 110 patients with metastatic colorectal cancer between January 1978 and September 1998 performed by a single surgeon were reviewed. RESULTS:The actuarial 5-year survival for all patients in the series was 46%. Of the patients operated on before 1993, the actual 5-year survival was 43% and actual disease-free 5-year survival was 28%. The actual 10-year survival was 27%, and of all patients operated on in the last 20 years, 48% are alive today. When comparing initial regional lymph node status, the 5-year survival was 54% for the patients with negative lymph nodes and 40% for patients with positive nodes. Only 18% of patients required a perioperative blood transfusion, and the median length of stay was 7 days. There were complications in 34% of cases, and the operative mortality was 4%. CONCLUSIONS:Hepatic resection for metastatic colon cancer is safe, and significant longevity and cure can be obtained after resection.

journal_name

Am J Surg

authors

Harmon KE,Ryan JA Jr,Biehl TR,Lee FT

doi

10.1016/s0002-9610(99)00070-7

subject

Has Abstract

pub_date

1999-05-01 00:00:00

pages

402-4

issue

5

eissn

0002-9610

issn

1879-1883

pii

S0002-9610(99)00070-7

journal_volume

177

pub_type

杂志文章
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    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

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    authors: Garcia-Rodriguez JA,Puig-LaCalle J,Arnau C,Porta M,Vallvé C

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    更新日期:2020-06-01 00:00:00

  • Blood management in orthopedic surgery.

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  • Orthopedic surgery.

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    journal_title:American journal of surgery

    pub_type: 历史文章,杂志文章

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  • Experience with 998 cutaneous melanomas of the head and neck over 30 years.

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    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/0002-9610(91)90138-4

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  • Laparoscopic cholecystectomy under spinal anesthesia.

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    journal_title:American journal of surgery

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.amjsurg.2007.05.043

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  • Operative morbidity and risk factor assessment in melanoma patients undergoing inguinal lymph node dissection.

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    pub_type: 杂志文章

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  • Palisade dorsoventral lavage for neglected peritonitis.

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  • Single dose prophylaxis in elective cholecystectomy. A prospective, double-blind randomized study.

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    pub_type: 临床试验,杂志文章,随机对照试验

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    authors: Kaufman Z,Dinbar A

    更新日期:1986-11-01 00:00:00

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    pub_type: 杂志文章

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